专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07932259B2 Pyrrolo[2,3-d]pyrimidine derivatives substituted with a cyclic amino group 失效
标题翻译：被环状氨基取代的吡咯并[2,3-d]嘧啶衍生物
公开(公告)号：US07932259B2
公开(公告)日：2011-04-26
申请号：US12106873
申请日：2008-04-21
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Mikako Yamaguchi , Tomoko Tamita , Ludo E. J. Kennis , Marcel F. L. De Bruyn , Jean-Pierre A. M. Bongartz , Frans M. A. Van Den Keybus , Yves E. M. Van Roosbroeck , Marcel G. M. Luyckx , Robert J. M. Hendrickx
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Mikako Yamaguchi , Tomoko Tamita , Ludo E. J. Kennis , Marcel F. L. De Bruyn , Jean-Pierre A. M. Bongartz , Frans M. A. Van Den Keybus , Yves E. M. Van Roosbroeck , Marcel G. M. Luyckx , Robert J. M. Hendrickx
IPC分类号： C07D487/04 , A61K31/519 , A61P25/24 , A61P25/28 , A61P25/18 , A61P29/00
CPC分类号： C07D471/04 , C07D487/04 , C07F9/6561
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. This problem can be solved with a pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by formula [I] below which has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，脱发，肠易激综合征，睡眠障碍，癫痫，皮肤病，精神分裂症等。可以用由以下式[I]表示的环氨基取代的吡咯并嘧啶或吡咯并吡啶衍生物来解决问题，其具有对CRF受体的高亲和力，并且对于CRF被认为涉及的疾病是有效的。

2. 发明授权

US08455511B2 Pyrrolopyridine derivatives substituted with cyclic amino group 失效
标题翻译：被环状氨基取代的吡咯并吡啶衍生物
公开(公告)号：US08455511B2
公开(公告)日：2013-06-04
申请号：US12951556
申请日：2010-11-22
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Mikako Yamaguchi , Tomoko Tamita , Ludo E. J. Kennis , Marcel F. L. De Bruyn , Jean-Pierre A. M. Bongartz , Frans M. A. Van Den Keybus , Yves E. M. Van Roosbroeck , Marcel G. M. Luyckx , Robert J. M. Hendrickx
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Mikako Yamaguchi , Tomoko Tamita , Ludo E. J. Kennis , Marcel F. L. De Bruyn , Jean-Pierre A. M. Bongartz , Frans M. A. Van Den Keybus , Yves E. M. Van Roosbroeck , Marcel G. M. Luyckx , Robert J. M. Hendrickx
IPC分类号： C07D471/04 , A61K31/437 , C07D487/04 , A61K31/519 , A61P25/28 , A61P25/24 , A61P25/18
CPC分类号： C07D471/04 , C07D487/04 , C07F9/6561
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. This problem can be solved with a pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by formula [I] below which has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，脱发，肠易激综合征，睡眠障碍，癫痫，皮肤病，精神分裂症等。可以用由以下式[I]表示的环氨基取代的吡咯并嘧啶或吡咯并吡啶衍生物来解决问题，其具有对CRF受体的高亲和力，并且对于CRF被认为涉及的疾病是有效的。

3. 发明授权

US08106194B2 Pyrrolopyrimidine and pyrrolotriazine derivatives 失效
标题翻译：吡咯并嘧啶和吡咯并三嗪衍生物
公开(公告)号：US08106194B2
公开(公告)日：2012-01-31
申请号：US10584946
申请日：2005-01-06
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
IPC分类号： C07D251/02 , C07D251/42 , C07D239/70
CPC分类号： C07D487/04
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, dermatitides, schizophrenia, pain, etc. A pyrrolopyrimidine or pyrrolotriazine derivative substituted with a carbamoyl group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，特异性，肠易激综合征，睡眠障碍，皮肤病，精神分裂症，疼痛等。由下式[I]表示的氨基甲酰基取代的吡咯并嘧啶或吡咯并三嗪衍生物：对CRF受体具有高亲和力，并且对于认为涉及CRF的疾病是有效的。

4. 发明授权

US07951811B2 Pyrrolo[2,3-D]pyrimidine derivatives substituted with a cyclic amino group 失效
标题翻译：被环状氨基取代的吡咯并[2,3-D]嘧啶衍生物
公开(公告)号：US07951811B2
公开(公告)日：2011-05-31
申请号：US11630042
申请日：2005-06-24
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
IPC分类号： C07D487/04 , A61K31/519 , A61P25/24 , A61P25/28 , A61P25/16 , A61P29/00
CPC分类号： C07D471/04 , C07D487/04
摘要： [PROBLEM TO BE SOLVED]An object of the present invention is to provide an antagonist against CRF receptors and/or an agonist for δ receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal diseases, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, pain, etc.[SOLUTION]A pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by the following a [I] has a high affinity for CRF receptors and/or δ receptors, and is effective against diseases in which CRF is considered to be involved.
摘要翻译： [待解决的问题]本发明的目的是提供一种抗CRF受体拮抗剂和/或对δ受体的激动剂，其有效作为涉及CRF的疾病的治疗或预防剂，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食障碍，高血压，胃肠道疾病，药物依赖，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，脱发，肠易激综合征，睡眠障碍，癫痫，皮肤病，精神分裂症，疼痛等。解决方案：由以下[I]表示的环状氨基取代的吡咯并嘧啶或吡咯并吡啶衍生物对CRF受体和/或δ受体具有高亲和性，并且是对抗CRF被认为参与的疾病有效。

5. 发明授权

US07557111B2 Substituted thieno[3,2-d]pyrimidines as CRF receptor antagonists 失效
标题翻译：取代的噻吩并[3,2-d]嘧啶作为CRF受体拮抗剂
公开(公告)号：US07557111B2
公开(公告)日：2009-07-07
申请号：US10584951
申请日：2005-01-06
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
IPC分类号： C07D495/04 , A61K31/519
CPC分类号： C07D495/04
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc.A thienopyrimidine or thienopyridine derivative substituted with a cyclic amino group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，特异性，肠易激综合征，睡眠障碍，癫痫，皮肤病，精神分裂症等。由下式[I]表示的环状氨基取代的噻吩并嘧啶或噻吩并吡啶衍生物对CRF受体具有高亲和力，对于认为涉及CRF的疾病有效。

6. 发明授权

US07365078B2 Triaza-cyclopenta[cd]indene derivatives 失效
标题翻译：三氮杂 - 环戊二烯并[cd]茚衍生物
公开(公告)号：US07365078B2
公开(公告)日：2008-04-29
申请号：US10584952
申请日：2005-01-06
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E. J. Kennis
IPC分类号： A01N43/54 , A61K31/505 , C07D239/00 , C07D471/00 , C07D487/00 , C07D491/00
CPC分类号： C07D487/16
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, dermatitides, schizophrenia, pain, etc. A triaza-cyclopenta[cd]indene derivative represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，特异性，肠易激综合征，睡眠障碍，皮肤病，精神分裂症，疼痛等。由下式[I]表示的三氮杂 - 环戊二烯并[cd]茚衍生物：对CRF受体具有高亲和力，并且对于CRF被认为涉及的疾病有效

7. 发明申请

US20110137031A1 PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES 失效
标题翻译：吡咯并嘧啶和吡咯烷酮衍生物
公开(公告)号：US20110137031A1
公开(公告)日：2011-06-09
申请号：US10584946
申请日：2005-01-06
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E.J. Kennis
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo E.J. Kennis
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, dermatitides, schizophrenia, pain, etc. A pyrrolopyrimidine or pyrrolotriazine derivative substituted with a carbamoyl group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，特异性，肠易激综合征，睡眠障碍，皮肤病，精神分裂症，疼痛等。由下式[I]表示的氨基甲酰基取代的吡咯并嘧啶或吡咯并三嗪衍生物：对CRF受体具有高亲和力，并且对于认为涉及CRF的疾病是有效的。

8. 发明申请

US20080287397A1 Pyrrolopyrimidine Derivatives Substituted with Cyclic Amino Group 失效
标题翻译：用环状氨基取代的吡咯并嘧啶衍生物
公开(公告)号：US20080287397A1
公开(公告)日：2008-11-20
申请号：US12106873
申请日：2008-04-21
申请人： Atsuro NAKAZATO , Taketoshi Okubo , Dai Nozawa , Mikako Yamaguchi , Tomoko Tamita , Ludo E.J. Kennis , Marcel F.L. De Bruyn , Jean-Pierre A.M. Bongartz , Frans M.A. Van Den Keybus , Yves E.M. Van Roosbroeck , Marcel G.M. Luyckx , Robert J.M. Hendrickx
发明人： Atsuro NAKAZATO , Taketoshi Okubo , Dai Nozawa , Mikako Yamaguchi , Tomoko Tamita , Ludo E.J. Kennis , Marcel F.L. De Bruyn , Jean-Pierre A.M. Bongartz , Frans M.A. Van Den Keybus , Yves E.M. Van Roosbroeck , Marcel G.M. Luyckx , Robert J.M. Hendrickx
IPC分类号： A61K31/661 , C07D487/04 , A61P25/00 , A61P17/00 , A61P1/00 , A61P29/00 , A61K31/519
CPC分类号： C07D471/04 , C07D487/04 , C07F9/6561
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. This problem can be solved with a pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by formula [I] below which has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗塞，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，脱发，肠易激综合征，睡眠障碍，癫痫，皮肤病，精神分裂症等。可以用由以下式[I]表示的环氨基取代的吡咯并嘧啶或吡咯并吡啶衍生物来解决问题，其具有对CRF受体的高亲和力，并且对于CRF被认为涉及的疾病是有效的。

9. 发明申请

US20070254898A1 Thienopyrimidine and Thienopyridine Derivatives Substituted with Cyclic Amino Group 失效
标题翻译：用环氨基取代的噻吩并嘧啶和噻吩并吡啶衍生物
公开(公告)号：US20070254898A1
公开(公告)日：2007-11-01
申请号：US10584951
申请日：2005-01-06
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo Kennis
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo Kennis
IPC分类号： A61K31/519 , A61K31/435 , C07D471/02 , C07D487/00
CPC分类号： C07D495/04
摘要： [Problem to be Solved] An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. [Solution] A thienopyrimidine or thienopyridine derivative substituted with a cyclic amino group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译： [待解决的问题]本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物有效，其中CRF被认为是涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默病，帕金森病疾病，亨廷顿氏舞蹈病，饮食失调，高血压，胃疾病，药物依赖，癫痫，脑梗死，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，特发性，肠易激综合征，睡眠障碍，癫痫，皮肤病，精神分裂症等。[溶液]由下式[I]表示的环状氨基取代的噻吩并嘧啶或噻吩并吡啶衍生物对CRF受体具有高亲和力，对于CRF被认为是涉及的疾病有效。

10. 发明申请

US20050209253A1 Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group 审中-公开
标题翻译：吡咯并嘧啶和环状氨基取代的吡咯并吡啶衍生物
公开(公告)号：US20050209253A1
公开(公告)日：2005-09-22
申请号：US10504981
申请日：2003-12-24
申请人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Mikato Yamaguchi , Tomoko Tamita , Ludo Kennis , Marcel De Bruyn , Jean-Pierre Bongartz , Frans Van Den Keybus , Yves Van Roosbroeck , Marcel Luyckx , Robert Hendrickx
发明人： Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Mikato Yamaguchi , Tomoko Tamita , Ludo Kennis , Marcel De Bruyn , Jean-Pierre Bongartz , Frans Van Den Keybus , Yves Van Roosbroeck , Marcel Luyckx , Robert Hendrickx
IPC分类号： A61K31/436 , A61K31/437 , A61K31/519 , A61K31/661 , A61P1/00 , A61P1/04 , A61P9/10 , A61P9/12 , A61P17/00 , A61P17/14 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/36 , A61P29/00 , A61P37/00 , A61P43/00 , C07D471/04 , C07D471/08 , C07D487/04 , C07D491/08 , C07D519/00 , C07F9/59 , C07F9/6561 , C07D471/02 , A61K31/4745
CPC分类号： C07D471/04 , C07D487/04 , C07F9/6561
摘要： An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. [Solution] A pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
摘要翻译：本发明的目的是提供一种抗CRF受体的拮抗剂，其作为治疗或预防药物是有效的，其涉及CRF被认为涉及的疾病，例如抑郁症，焦虑症，阿尔茨海默氏病，帕金森病，亨廷顿氏舞蹈病，进食疾病，高血压，胃疾病，药物依赖，癫痫，脑梗死，脑缺血，脑水肿，头部外伤，炎症，免疫相关疾病，脱发，肠易激综合征，睡眠障碍，癫痫，皮肤病，精神分裂症等。溶液]由下式[I]表示的环状氨基取代的吡咯并嘧啶或吡咯并吡啶衍生物对CRF受体具有高亲和力，对于被认为涉及CRF的疾病有效。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式