专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20180067136A1 ATOMIC THERAPEUTIC INDICATOR 审中-公开
公开(公告)号：US20180067136A1
公开(公告)日：2018-03-08
申请号：US15717246
申请日：2017-09-27
申请人： Atomic Oncology Pty Ltd
发明人： George L. Gabor Miklos
IPC分类号： G01N33/84 , G01N33/574
CPC分类号： G01N33/84 , G01N21/3103 , G01N21/718 , G01N22/00 , G01N23/085 , G01N23/223 , G01N33/574 , G01N2223/402 , G01N2223/6126 , G01N2800/52 , H01J49/161
摘要： The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X′xY′xZ. The ATI is used to assess the radio-responsiveness i.e. sensitivity or resistance to radiation treatment, of a cancer i.e. a tumour/neoplasm. In a preferred embodiment, the present invention relates to a method of generating the ATI, assessing the radio-responsiveness of a tumour/neoplasm based on the ATI and, based on the assessment, either treating or not treating the tumour with radiation.The present invention also relates to a method of determining if a cancer is likely to reoccur post radiation treatment comprising quantifying the level of manganese in voxels of a 3D region of a test sample from the cancer and determining the frequency of high metallomic regions (HMRs) in the cancer, wherein a high frequency of HMRs is indicative that the cancer is likely to reoccur and a low frequency of HMRs is indicative that the cancer is unlikely to reoccur; and associated methods of treatment.The invention further relates to a method of determining the radio-responsiveness of a melanoma, the method comprising determining the level of melanin in a test sample from the melanoma, wherein the lower the level of melanin the more sensitive the melanoma is to radiation and the higher the level of melanin the more resistant the melanoma is to radiation; and associated methods of treatment.

2. 发明授权

US10302661B2 Method for treating a cancer patient based on atomic therapeutic indexes and non-radiation therapy 有权
公开(公告)号：US10302661B2
公开(公告)日：2019-05-28
申请号：US15717246
申请日：2017-09-27
申请人： Atomic Oncology Pty Ltd
发明人： George L. Gabor Miklos
IPC分类号： G01N21/31 , G01N21/71 , G01N22/00 , G01N33/84 , H01J49/16 , G01N23/085 , G01N23/223 , G01N33/574 , G01N33/48
摘要： The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X′×Y′×Z. The ATI is used to assess the radio-responsiveness i.e. sensitivity or resistance to radiation treatment, of a cancer i.e. a tumor/neoplasm. In a preferred embodiment, the present invention relates to a method of generating the ATI, assessing the radio-responsiveness of a tumor/neoplasm based on the ATI and, based on the assessment, either treating or not treating the tumor with radiation.The present invention also relates to a method of determining if a cancer is likely to reoccur post radiation treatment comprising quantifying the level of manganese in voxels of a 3D region of a test sample from the cancer and determining the frequency of high metallomic regions (HMRs) in the cancer, wherein a high frequency of HMRs is indicative that the cancer is likely to reoccur and a low frequency of HMRs is indicative that the cancer is unlikely to reoccur; and associated methods of treatment.The invention further relates to a method of determining the radio-responsiveness of a melanoma, the method comprising determining the level of melanin in a test sample from the melanoma, wherein the lower the level of melanin the more sensitive the melanoma is to radiation and the higher the level of melanin the more resistant the melanoma is to radiation; and associated methods of treatment.

3. 发明授权

US10254284B2 Method for treating a cancer patient based on atomic therapeutic indexes and radiation 有权
公开(公告)号：US10254284B2
公开(公告)日：2019-04-09
申请号：US15517112
申请日：2016-07-11
申请人： ATOMIC ONCOLOGY PTY LTD
发明人： George L. Gabor Miklos
IPC分类号： A61N5/10 , G01N33/50 , G01N33/84 , G01N33/483 , G01N33/574 , G01N33/48
摘要： The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X′×Y′×Z. The ATI is used to assess the radio-responsiveness i.e. sensitivity or resistance to radiation treatment, of a cancer i.e. a tumor/neoplasm. In a preferred embodiment, the present invention relates to a method of generating the ATI, assessing the radio-responsiveness of a tumor/neoplasm based on the ATI and, based on the assessment, either treating or not treating the tumor with radiation. The present invention also relates to a method of determining if a cancer is likely to reoccur post radiation treatment comprising quantifying the level of manganese in voxels of a 3D region of a test sample from the cancer and determining the frequency of high metallomic regions (HMRs) in the cancer, wherein a high frequency of HMRs is indicative that the cancer is likely to reoccur and a low frequency of HMRs is indicative that the cancer is unlikely to reoccur; and associated methods of treatment.

4. 发明申请

US20180143197A1 ATOMIC THERAPEUTIC INDICATOR 审中-公开
公开(公告)号：US20180143197A1
公开(公告)日：2018-05-24
申请号：US15517112
申请日：2016-07-11
申请人： ATOMIC ONCOLOGY PTY LTD
发明人： George L. Gabor Miklos
IPC分类号： G01N33/574 , G01N33/84
CPC分类号： G01N33/574 , A61N5/1039 , G01N33/4833 , G01N33/5035 , G01N33/84 , G01N2800/52
摘要： The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X′×Y′×Z. The ATI is used to assess the radio-responsiveness i.e. sensitivity or resistance to radiation treatment, of a cancer i.e. a tumour/neoplasm. In a preferred embodiment, the present invention relates to a method of generating the ATI, assessing the radio-responsiveness of a tumour/neoplasm based on the ATI and, based on the assessment, either treating or not treating the tumour with radiation. The present invention also relates to a method of determining if a cancer is likely to reoccur post radiation treatment comprising quantifying the level of manganese in voxels of a 3D region of a test sample from the cancer and determining the frequency of high metallomic regions (HMRs) in the cancer, wherein a high frequency of HMRs is indicative that the cancer is likely to reoccur and a low frequency of HMRs is indicative that the cancer is unlikely to reoccur; and associated methods of treatment.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式