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1. 发明授权

US5985120A Rapid analysis of analyte solutions 失效
标题翻译：快速分析分析物溶液
公开(公告)号：US5985120A
公开(公告)日：1999-11-16
申请号：US873473
申请日：1997-06-12
申请人： Ashok L. Cholli , Eugene F. Barry , Sukant K. Tripathy , Jayant Kumar
发明人： Ashok L. Cholli , Eugene F. Barry , Sukant K. Tripathy , Jayant Kumar
IPC分类号： G01N27/447 , G01N27/26
CPC分类号： G01N27/44721 , G01N27/44717
摘要： The separation profile results of capillary zone electrophoresis can be analyzed very rapidly, e.g., in 45 seconds or less, if the results are analyzed using a successive subtracting procedure to establish the separation profile as a function of time and projecting this separation profile forward in time to quantitatively analyze the separate species in the profile. The projection step can be accomplished using an algorithm along with or without Fourier transform (FT) techniques and the quantitative analysis can be carried out using principle component regression analysis (PCA) or suitable calibration procedures.
摘要翻译：毛细管区带电泳的分离曲线结果可以非常快速地分析，例如，在45秒或更短时间内，如果使用连续的减法程序分析结果以建立作为时间的函数的分离曲线并且在时间上向前投影该分离曲线定量分析轮廓中的单独物种。投影步骤可以使用与傅立叶变换（FT）技术一起使用的算法来实现，并且可以使用主成分回归分析（PCA）或适当的校准程序进行定量分析。

2. 发明授权

US5846753A Chemiluminescence-based method for rapid and sensitive in-situ detection of organophosphorus compounds and metal ions 失效
标题翻译：基于化学发光的方法，用于快速和灵敏地原位检测有机磷化合物和金属离子
公开(公告)号：US5846753A
公开(公告)日：1998-12-08
申请号：US445565
申请日：1995-05-30
申请人： Joseph A. Akkara , David L. Kaplan , Madhu S. R. Ayyagari , Kenneth A. Marx , Sanjay Kamtekar , Rajiv Pande , Sukant K. Tripathy , Jayant Kumar
发明人： Joseph A. Akkara , David L. Kaplan , Madhu S. R. Ayyagari , Kenneth A. Marx , Sanjay Kamtekar , Rajiv Pande , Sukant K. Tripathy , Jayant Kumar
IPC分类号： C12Q1/42 , C07D305/14 , C12Q1/44
CPC分类号： C12Q1/42 , C12Q2334/00
摘要： A method of detecting the presence of a substance being monitored in a medium, selected from the group of substances including organophosphorus compounds and the metal ions Zn, Be and Bi, including the steps of: providing a 1,2-dioxetane phenyl phosphate compound; providing a phosphatase that catalytically degrades the 1,2-dioxetane phenyl phosphate compound to produce light, the catalytic activity of the phosphatase toward 1,2-dioxetane phenyl phosphate compound being altered by the substance being monitored; exposing the 1,2-dioxetane phenyl phosphate compound and the phosphatase together to a medium which may contain the substance being monitored; detecting light produced after the exposing step; and determining, from the detected light, the presence and concentration in the medium of the substance being monitored.
摘要翻译：一种检测在包括有机磷化合物和金属离子Zn，Be和Bi的物质组中的介质中被监测物质的存在的方法，包括以下步骤：提供1,2-二氧环乙烷苯基磷酸酯化合物; 提供催化降解1,2-二氧杂环丁烷苯基磷酸酯化合物以产生光的磷酸酶，磷酸酯对正在监测的物质的1,2-二氧环乙烷苯基磷酸酯化合物的催化活性改变; 将1,2-二氧环乙烷苯基磷酸酯化合物和磷酸酶一起暴露于可能含有被监测物质的介质中; 检测曝光步骤后产生的光; 并且从检测到的光中确定被监测物质的介质中的存在和浓度。

3. 发明授权

US5433895A Silicon-containing networked non-linear optical compositions 失效
标题翻译：含硅网络非线性光学组合物
公开(公告)号：US5433895A
公开(公告)日：1995-07-18
申请号：US950398
申请日：1992-09-23
申请人： Ru J. Jeng , Yong M. Chen , Aloke K. Jain , Jayant Kumar , Sukant K. Tripathy
发明人： Ru J. Jeng , Yong M. Chen , Aloke K. Jain , Jayant Kumar , Sukant K. Tripathy
IPC分类号： G02F1/355 , G02F1/361 , F21V9/00
CPC分类号： G02F1/3555 , G02F1/361 , G02F1/3615
摘要： A nonlinear optical composition and a method of forming the nonlinear optical composition are disclosed. The nonlinear optical composition includes a silicon-containing component and a nonlinear optical component which causes the nonlinear optical composition to exhibit second order nonlinear optical polarization of electromagnetic radiation, such as light. The method includes forming a sol of the silicon-containing component and the nonlinear optical component of the composition. A gel is formed from the sol. The nonlinear optical component is then poled while the gel is exposed to conditions sufficient to cause formation of a nonlinear optical composition which exhibits second order nonlinear optical polarization of electromagnetic radiation.
摘要翻译：公开了非线性光学组合物和形成非线性光学组合物的方法。非线性光学组合物包括含硅组分和非线性光学组分，其使得非线性光学组合物显示诸如光的电磁辐射的二阶非线性光学偏振。该方法包括形成含硅组分的溶胶和该组合物的非线性光学组分。由溶胶形成凝胶。然后将非线性光学部件极化，同时将凝胶暴露于足以形成非线性光学组合物的条件，其呈现电磁辐射的二阶非线性光学偏振。

4. 发明授权

US6018018A Enzymatic template polymerization 失效
标题翻译：酶模板聚合
公开(公告)号：US6018018A
公开(公告)日：2000-01-25
申请号：US999542
申请日：1997-11-21
申请人： Lynne A. Samuelson , K. Shridhara Alva , Jayant Kumar , Sukant K. Tripathy
发明人： Lynne A. Samuelson , K. Shridhara Alva , Jayant Kumar , Sukant K. Tripathy
IPC分类号： C08G73/02 , H01B1/12 , C08G73/00
CPC分类号： C08G73/0266 , H01B1/128 , Y10S977/747
摘要： Polymers are formed enzymatically in the presence of an oligomeric or polymeric template. The method includes combining at least one redox monomer or, in some cases, a redox oligomer, with a template and an enzyme, such as horseradish peroxidase, to form a reaction mixture. The redox monomer or oligomer aligns along the template before or during the polymerization, the template thereby affecting at least one physical property of the resulting polymer, such as the molecular weight or shape of the polymer. In one embodiment, the template can be a polyelectrolyte or an optically active polymer.
摘要翻译：在低聚或聚合物模板存在下，酶促形成聚合物。该方法包括将至少一种氧化还原单体，或在一些情况下，将氧化还原低聚物与模板和酶如辣根过氧化物酶组合以形成反应混合物。氧化还原单体或低聚物在聚合之前或期间沿模板排列，从而影响所得聚合物的至少一种物理性能，例如聚合物的分子量或形状。在一个实施方案中，模板可以是聚电解质或旋光聚合物。

5. 发明授权

US5260004A Process of making Langmuir-Blodgett films having photo-electronic properties 失效
标题翻译：制作具有光电特性的Langmuir-Blodgett薄膜的工艺
公开(公告)号：US5260004A
公开(公告)日：1993-11-09
申请号：US802675
申请日：1991-12-02
申请人： Lynne A. Samuelson , David L. Kaplan , Kenneth A. Marx , Sukant K. Tripathy , Jayant Kumar
发明人： Lynne A. Samuelson , David L. Kaplan , Kenneth A. Marx , Sukant K. Tripathy , Jayant Kumar
IPC分类号： B05D1/20 , B29C41/12 , B29C67/24 , B29C41/02 , B29C71/02 , B29C71/04
CPC分类号： B82Y30/00 , B05D1/202 , B29C41/12 , B29C67/24 , B82Y40/00 , B29K2089/00
摘要： Langmuir-Blodgett films having photo-electronic properties and methods of making the same. The instant films may be made, for example, by spreading a mixture of one or more types of biotinylated lipids and one or more types of electrically-conductive lipids over a water-miscible liquid subphase. Conjugated molecules comprising a biotin-binding component made up of an avidin or streptavidin molecule or a fragment or derivative thereof having biotin-binding activity and a photodynamic proteinaceous component are then injected into the subphase. Because of the affinity between biotin and the biotin-binding component, the conjugated molecules bind to the biotinylated lipids. The air-subphase interface is then compressed, causing the biotinylated lipids and electrically-conductive lipids to form a monolayer thereat. In one embodiment, the biotin-binding component has biotin-binding sites available on its underside which may be used to bind biotinylated derivatives of one or more different species of photodynamic proteinaceous components and/or to build up a multilayered complex of biotin-binding molecules and functional proteinaceous components using biotinylated rigid or flexible couplers.
摘要翻译：具有光电特性的Langmuir-Blodgett薄膜及其制造方法。可以例如通过将一种或多种类型的生物素化脂质和一种或多种类型的导电脂质的混合物铺在水混溶液体相上来制备即时膜。然后将包含由具有生物素结合活性的抗生物素蛋白或链霉抗生物素蛋白分子或其片段或衍生物的生物素结合组分的结合分子和光动力学蛋白质组分注入到亚相中。由于生物素与生物素结合成分之间的亲和力，共轭分子与生物素化的脂质结合。然后将空气 - 亚相界面压缩，导致生物素化的脂质和导电脂质在其上形成单层。在一个实施方案中，生物素结合组分在其下侧具有可用的生物素结合位点，其可用于结合一种或多种不同种类的光动力蛋白质组分的生物素化衍生物和/或建立生物素结合分子的多层复合物和使用生物素化的刚性或柔性耦合剂的功能蛋白质组分。

6. 发明授权

US06569651B1 Enzymatic polymerization of anilines or phenols around a template 失效
标题翻译：苯胺或酚类在模板周围的酶聚合
公开(公告)号：US06569651B1
公开(公告)日：2003-05-27
申请号：US09334105
申请日：1999-06-16
申请人： Lynne A. Samuelson , Sukant K. Tripathy , Ferdinando Bruno , Ramaswamy Nagarajan , Jayant Kumar , Wei Liu
发明人： Lynne A. Samuelson , Sukant K. Tripathy , Ferdinando Bruno , Ramaswamy Nagarajan , Jayant Kumar , Wei Liu
IPC分类号： C12P1300
CPC分类号： C12P13/001 , C12P7/22 , Y10S435/817 , Y10S977/898
摘要： The micelle contains multiple units, each of which contains a hydrophobic part and a hydrophilic part. A preferred unit is dodecyl benzene sulfonic acid. Borate-containing electrolytes include trifluoroborate, trimethylborate and hydrobis(pyridine)boron. Enzymes include peroxidases such as horseradish peroxidase or lignin peroxidase, and laccase. Monomers include unsubstituted and substituted anilines and unsubstituted and substituted phenols. A method is provided for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction mixture for a time and under conditions sufficient for the monomer to align along the template and polymerize to form a polymer-template complex. The template can be a micelle, a borate-containing electrolyte, or lignin sulfonate. The polymer-template complex may be conductive, and possesses exceptional electrical and optical stability, water solubility, and processibility, and can be used in applications such as light-weight energy storage devices (e.g., rechargeable batteries), electrolytic capacitors, anti-static and anti-corrosive coatings for smart windows, and biological sensors.
摘要翻译：胶束含有多个单元，每个单元含有疏水部分和亲水部分。优选的单元是十二烷基苯磺酸。含硼酸盐的电解质包括三氟硼酸盐，硼酸三甲酯和氢化双（吡啶）硼。酶包括过氧化物酶如辣根过氧化物酶或木质素过氧化物酶，以及漆酶。单体包括未取代的和取代的苯胺和未取代的和取代的酚。提供了一种用于酶促聚合的方法，其包括（1）获得包含单体，模板和酶的反应混合物; 和（2）将反应混合物温育一段时间并在足以使单体沿着模板排列的聚合物形成聚合物 - 模板复合物的条件下。模板可以是胶束，含硼酸盐的电解质或木质素磺酸盐。聚合物 - 模板复合物可以是导电的，并且具有优异的电和光学稳定性，水溶性和可加工性，并且可以用于诸如轻量储能装置（例如可再充电电池），电解电容器，防静电以及智能窗户和生物传感器的防腐涂料。

7. 发明授权

US5532320A Second order nonlinear optical interpenetrating polymer networks 失效
标题翻译：二阶非线性光学互穿聚合物网络
公开(公告)号：US5532320A
公开(公告)日：1996-07-02
申请号：US361278
申请日：1994-12-21
申请人： Sukant K. Tripathy , Ru-Jong Jeng , Jayant Kumar , Sutiyao Marturunkakul , Jeng-I Chen
发明人： Sukant K. Tripathy , Ru-Jong Jeng , Jayant Kumar , Sutiyao Marturunkakul , Jeng-I Chen
IPC分类号： C08F8/14 , G02F1/361 , G03F7/00 , G03F7/038 , C08L63/00 , C08F20/34 , C08L83/08
CPC分类号： G03F7/001 , C08F8/14 , G02F1/3617 , G03F7/0388 , Y10S525/903
摘要： A nonlinear optical interpenetrating polymer network which can exhibit nonlinear optical properties includes a first polymer, and a second polymer interpenetrating the first polymer. At least one of the polymers includes a nonlinear optical component. A method of forming a nonlinear optical interpenetrating polymer network which can exhibit nonlinear optical properties includes combining a first prepolymer, which can react to form a first polymer, with at least one monomer which can react to form a second polymer. At least one of either the first prepolymer or the monomer include a nonlinear optical component. The nonlinear optical component is poled and the first prepolymer and the monomer, or monomers, of the second prepolymer are reacted while the nonlinear optical component is being poled. The reaction of the first prepolymer forms a first polymer network and reaction of the monomer(s) form a second polymer network which interpenetrates the first polymer network to form an interpenetrating polymer network. The interpenetrating polymer network fixes the nonlinear optical component in the poled position, thereby forming an interpenetrating polymer network which exhibits nonlinear optical properties.
摘要翻译：可以显示非线性光学性质的非线性光学互穿聚合物网络包括第一聚合物和互穿第一聚合物的第二聚合物。聚合物中的至少一种包括非线性光学部件。形成可显示非线性光学性质的非线性光学互穿聚合物网络的方法包括将可与反应形成第一聚合物的第一预聚物与至少一种可反应形成第二聚合物的单体组合。第一预聚物或单体中的至少一种包括非线性光学组分。非线性光学部件被极化，并且第二预聚物的第一预聚物和单体或单体在非线性光学部件被极化的同时反应。第一预聚物的反应形成第一聚合物网络，并且单体的反应形成第二聚合物网络，其互穿第一聚合物网络以形成互穿聚合物网络。互穿聚合物网络将非线性光学部件固定在极化位置，从而形成呈现非线性光学性质的互穿聚合物网络。

8. 发明授权

US5112881A Photocrosslinked second order nonlinear optical polymers 失效
标题翻译：光交联二阶非线性光学聚合物
公开(公告)号：US5112881A
公开(公告)日：1992-05-12
申请号：US573253
申请日：1990-08-24
申请人： Braja K. Mandal , Sukant K. Tripathy , Jan-Chan Huang , Jayant Kumar
发明人： Braja K. Mandal , Sukant K. Tripathy , Jan-Chan Huang , Jayant Kumar
IPC分类号： C08F2/46 , C08F8/14 , G02F1/361 , G03F7/00 , G03F7/038
CPC分类号： G03F7/001 , C08F8/14 , G02F1/3617 , G03F7/0388 , C08F2810/30 , Y10S430/12
摘要： A novel photocrosslinkable polymeric system has been developed for processing into films having stable second-order nonlinear optical properties. In the present system, polymers bearing photocrosslinkable chromophores, such as polyvinylcinnamate and are reacted with appropriately designed nonlinear optical molecules with the cinnamate or other photocrosslinkable functionalities for photocrosslinking at one, two or more points. The system can be poled and photocrosslinked in the poled state to yield a material with stable optical nonlinearity and large electro-optic coefficients.
摘要翻译：已经开发了一种新颖的可光交联聚合物体系，用于加工成具有稳定二阶非线性光学性质的膜。在本系统中，含有光可交联发色团的聚合物如聚乙烯基肉桂酸酯，并与适当设计的非线性光学分子与肉桂酸酯或其它可光交联官能团反应，以在一个，两个或更多个点进行光致交联。该系统可以在极化状态下被极化和光交联，以产生具有稳定的光学非线性和大的电光系数的材料。

9. 发明授权

US5484821A Photocrosslinked second order nonlinear optical polymers 失效
标题翻译：光交联二阶非线性光学聚合物
公开(公告)号：US5484821A
公开(公告)日：1996-01-16
申请号：US192785
申请日：1994-02-07
申请人： Braja K. Mandal , Sukant K. Tripathy , Jan-Chan Huang , Jayant Kumar
发明人： Braja K. Mandal , Sukant K. Tripathy , Jan-Chan Huang , Jayant Kumar
IPC分类号： C08F2/46 , C08F8/14 , G02F1/361 , G03F7/00 , G03F7/038 , C08J3/28
CPC分类号： G03F7/001 , C08F8/14 , G02F1/3617 , G03F7/0388 , C08F2810/30 , Y10S430/12
摘要： A novel photocrosslinkable polymeric system has been developed for processing into films having stable second-order nonlinear optical properties. In the present system, polymers bearing photo-crosslinkable chromophores, such as polyvinylcinnamate and are reacted with appropriately designed nonlinear optical molecules with the cinnamate or other photocrosslinkable functionalities for photocrosslinking at one, two or more points. The system can be poled and photocrosslinked in the poled state to yield a material with stable optical nonlinearity and large electro-optic coefficients.
摘要翻译：已经开发了一种新颖的可光交联聚合物体系，用于加工成具有稳定二阶非线性光学性质的膜。在本系统中，含有光可交联发色团的聚合物如聚乙烯基肉桂酸酯，并与适当设计的非线性光学分子与肉桂酸酯或其它可光交联官能团反应，用于在一个，两个或更多个点进行光致交联。该系统可以在极化状态下被极化和光交联，以产生具有稳定的光学非线性和大的电光系数的材料。

10. 发明授权

US5438192A Photodynamic protein-based photodetector and photodetector system for image detection and processing 失效
标题翻译：光动力蛋白质光电探测器和光电探测器系统，用于图像检测和处理
公开(公告)号：US5438192A
公开(公告)日：1995-08-01
申请号：US166398
申请日：1993-12-09
申请人： David L. Kaplan , Lynne A. Samuelson , Bonnie J. Wiley , Kenneth A. Marx , Jayant Kumar , Sukant K. Tripathy , Sandip K. Sengupta , Mario J. Cazeca
发明人： David L. Kaplan , Lynne A. Samuelson , Bonnie J. Wiley , Kenneth A. Marx , Jayant Kumar , Sukant K. Tripathy , Sandip K. Sengupta , Mario J. Cazeca
IPC分类号： G01J1/42 , H01L31/08 , H01L51/30 , H01J40/14
CPC分类号： H01L51/42 , B82Y10/00 , H01L51/0093 , H01L27/307 , Y02E10/549 , Y10S428/919
摘要： A photodetection device uses configurations of photodynamic proteins which exhibit a change in electrical conductivity in response to a corresponding change in incident light intensity in the presence of an applied voltage. The photodynamic proteins are coupled to an electrical conductor, a voltage source and a conductivity sensor. The photodynamic protein complex includes at least one layer of a photodynamic protein and preferably includes a multi-layered thin-film structure with each layer comprised of either a photodynamic protein or a conductive polymer or oligomer. Groups of linked photodetectors where the photodetectors have different, but overlapping, spectral response ranges are used to detect specific wavelengths of incident light. An array of these groups of linked photodetectors arranged in a predetermined spatial pattern allows detection of both colon and images. An image processing system is constructed from this array of groups of linked photodetectors by coupling the output of the array to a processing component and the output of the processing component to an output device. A dynamic adaptive camouflage system is derived from the image processing system by mounting the photodetectors and display devices on an apparatus to be camouflaged and displaying a spatially shifted image of the incident ambient light.
摘要翻译：光电检测装置使用光动力学蛋白质的配置，其响应于存在施加电压的入射光强度的相应变化而呈现导电性变化。光动力学蛋白质耦合到电导体，电压源和电导率传感器。光动力学蛋白质复合物包括至少一层光动力学蛋白质，并且优选地包括具有由光动力学蛋白质或导电聚合物或低聚物组成的每层的多层薄膜结构。光电探测器具有不同但重叠的光谱响应范围的联接光电检测器组被用于检测入射光的特定波长。以预定的空间图案布置的这些组的相连的光电探测器的阵列允许检测结肠和图像。通过将阵列的输出耦合到处理部件和将处理部件的输出耦合到输出装置，从这组连接的光电检测器组构成图像处理系统。通过将光电检测器和显示装置安装在要伪装的装置上并显示入射环境光的空间位移图像，从图像处理系统得到动态适应伪装系统。

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