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1. 发明申请

US20050244410A1 Toll-like receptor 9 effector agents and uses thereof 审中-公开
标题翻译： Toll样受体9效应物及其用途
公开(公告)号：US20050244410A1
公开(公告)日：2005-11-03
申请号：US10835475
申请日：2004-04-29
申请人： Ashlyn Bassiri , Anuk Das , Susan Dillon , Karen Duffy , Jonathan Seideman , M. Mbow , Lars Karlsson , Siquan Sun , Jian Zhu , Mark Cunningham
发明人： Ashlyn Bassiri , Anuk Das , Susan Dillon , Karen Duffy , Jonathan Seideman , M. Mbow , Lars Karlsson , Siquan Sun , Jian Zhu , Mark Cunningham
IPC分类号： A61K39/395 , A61K48/00 , C07K16/28
CPC分类号： C07K16/2896 , C07K2317/34
摘要： Cell surface TLR9 and TLR9 ligand binding agents are disclosed. The binding agents include antibodies and other proteins. The binding agents are useful as therapeutics, diagnostics or research reagents.
摘要翻译：公开了细胞表面TLR9和TLR9配体结合剂。结合剂包括抗体和其它蛋白质。结合剂可用作治疗剂，诊断或研究试剂。

2. 发明申请

US20060115475A1 Toll like receptor 3 antagonists, methods and uses 有权
标题翻译： Toll样受体3拮抗剂，方法和用途
公开(公告)号：US20060115475A1
公开(公告)日：2006-06-01
申请号：US11291140
申请日：2005-11-30
申请人： Jill Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Mouhamadou Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
发明人： Jill Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Mouhamadou Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译： Toll样受体3（TLR3）拮抗剂，编码TLR3拮抗剂或其片段的多核苷酸，以及制备和使用前述物质的方法。

3. 发明授权

US08153583B2 Toll like receptor 3 antagonists, methods and uses 有权
标题翻译： Toll样受体3拮抗剂，方法和用途
公开(公告)号：US08153583B2
公开(公告)日：2012-04-10
申请号：US11291140
申请日：2005-11-30
申请人： Jill M. Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill M. Giles-Komar , Theresa J. Goletz , David M. Knight , Roberta Lamb , Mouhamadou L. Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert T. Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
发明人： Jill M. Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill M. Giles-Komar , Theresa J. Goletz , David M. Knight , Roberta Lamb , Mouhamadou L. Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert T. Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
IPC分类号： A61K38/00 , C07K16/00
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists, and methods of making and using the foregoing are disclosed.
摘要翻译：公开了Toll样受体3（TLR3）拮抗剂，编码TLR3拮抗剂的多核苷酸，以及制备和使用前述物质的方法。

4. 发明申请

US20140255388A1 TOLL LIKE RECEPTOR 3 ANTAGONISTS, METHODS AND USES 审中-公开
标题翻译： TOLL LIKE RECEPTOR 3 ANTAGONISTS，METHODS AND USES
公开(公告)号：US20140255388A1
公开(公告)日：2014-09-11
申请号：US13799476
申请日：2013-03-13
申请人： Jill M. Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Lamine Mbow , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Nicole Stowell , Raymond Sweet , Shanrong Zhao
发明人： Jill M. Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Lamine Mbow , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Nicole Stowell , Raymond Sweet , Shanrong Zhao
IPC分类号： C07K16/28
CPC分类号： C07K16/2866 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/74 , C07K2317/76
摘要： Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments, and methods of making and using the foregoing are disclosed.
摘要翻译： Toll样受体3（TLR3）拮抗剂，编码TLR3拮抗剂或片段的多核苷酸，以及制备和使用前述物质的方法。

5. 发明申请

US20120189643A1 Toll Like Receptor 3 Antagonists, Methods and Uses 审中-公开
标题翻译： Toll Like Receptor 3 Antagonists，Methods and Uses
公开(公告)号：US20120189643A1
公开(公告)日：2012-07-26
申请号：US13412259
申请日：2012-03-05
申请人： Jill M. Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill M. Giles-Komar , Theresa J. Goletz , David M. Knight , Roberta Lamb , Mouhamadou L. Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert T. Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
发明人： Jill M. Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill M. Giles-Komar , Theresa J. Goletz , David M. Knight , Roberta Lamb , Mouhamadou L. Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert T. Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
IPC分类号： A61K39/395 , C12N15/13 , C12N15/63 , C12N1/21 , A61P3/10 , C12P21/00 , C12N5/16 , A61P29/00 , A61P1/00 , A61P11/00 , C07K16/28 , C12N5/10
CPC分类号： C07K16/2866 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/74 , C07K2317/76
摘要： Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译： Toll样受体3（TLR3）拮抗剂，编码TLR3拮抗剂或其片段的多核苷酸，以及制备和使用前述物质的方法。

6. 发明申请

US20070203064A1 TLR3 Glycosylation Site Muteins and Methods of Use 审中-公开
标题翻译： TLR3糖基化位点突变蛋白和使用方法
公开(公告)号：US20070203064A1
公开(公告)日：2007-08-30
申请号：US11554253
申请日：2006-10-30
申请人： Karen Duffy , Mark Cunningham , M. Mbow , Robert Sarisky
发明人： Karen Duffy , Mark Cunningham , M. Mbow , Robert Sarisky
IPC分类号： A61K38/17 , A61K48/00 , C07K14/705
CPC分类号： C07K14/705 , A61K38/00 , A61K48/00
摘要： TLR3 glycosylation site muteins, nucleic acids encoding the muteins, and methods of modulating TLR3 activity in a cell are disclosed.
摘要翻译：公开了TLR3糖基化位点突变蛋白，编码突变蛋白的核酸和调节细胞中TLR3活性的方法。

7. 发明授权

US4824071A An apparatus used to fabricate a custom female urine collection device 失效
标题翻译：用于制造定制的尿液收集装置的装置
公开(公告)号：US4824071A
公开(公告)日：1989-04-25
申请号：US065325
申请日：1987-08-06
申请人： Karen Duffy , Helfer, Joel , Terese Campion
发明人： Karen Duffy , Helfer, Joel , Terese Campion
IPC分类号： A61F5/455 , B29C39/24 , B29C39/26
CPC分类号： A61F5/455
摘要： An impression cup of a female unogenital region for use in fabricating a customized female urine receptacle and having a rim and connecting wall portions defining an opening sufficient to surround the urethral opening, the wall portion also having another opening for introducing an impression material into the receptacle and means suitable for introducing an impression material into the opening in the wall portion.
摘要翻译：用于制造定制的女性尿液容器的女性非生殖区域的印模杯，并且具有限定足以包围尿道开口的开口的边缘和连接壁部分，壁部分还具有用于将印模材料引入到容器中的另一个开口以及适于将印模材料引入壁部分中的开口中的装置。

8. 发明申请

US20070098716A1 Toll Like Receptor 3 Modulators, Methods and Uses 有权
标题翻译： Toll Like Receptor 3调制器，方法和用途
公开(公告)号：US20070098716A1
公开(公告)日：2007-05-03
申请号：US11553633
申请日：2006-10-27
申请人： Karen Duffy , Chong Huang , Roberta Lamb , Mouhamadou Mbow , Robert Sarisky , Lani San Mateo
发明人： Karen Duffy , Chong Huang , Roberta Lamb , Mouhamadou Mbow , Robert Sarisky , Lani San Mateo
IPC分类号： A61K39/395 , C07H21/04 , C12P21/06 , C12N5/06 , C07K16/28
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2317/56 , C07K2317/567 , C07K2317/75
摘要： Toll Like Receptor 3 (TLR3) modulators, such as antibodies, polynucleotides encoding TLR3 antibodies or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译：公开了Toll样受体3（TLR3）调节剂，例如抗体，编码TLR3抗体的多核苷酸或其片段，以及制备和使用前述物质的方法。

9. 发明申请

US20130287777A1 ST2L Antagonists and Methods of Use 有权
公开(公告)号：US20130287777A1
公开(公告)日：2013-10-31
申请号：US13798226
申请日：2013-03-13
申请人： Karen Duffy , Natalie Fursov , LeRoy Hall , Catherine Healy , Roberta Lamb , Jinquan Luo , Ravi Malaviya , Michael Naso , Michael Pratta , Mark Tornetta , John Wheeler , Sheng-Jiu Wu
发明人： Karen Duffy , Natalie Fursov , LeRoy Hall , Catherine Healy , Roberta Lamb , Jinquan Luo , Ravi Malaviya , Michael Naso , Michael Pratta , Mark Tornetta , John Wheeler , Sheng-Jiu Wu
IPC分类号： C07K16/28
CPC分类号： C07K16/2866 , A61K38/012 , A61K39/3955 , A61K2039/505 , C07K16/44 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

10. 发明申请

US20090108205A1 NIRS SENSOR MOUNTING APPARATUS 审中-公开
标题翻译： NIRS传感器安装设备
公开(公告)号：US20090108205A1
公开(公告)日：2009-04-30
申请号：US12248556
申请日：2008-10-09
申请人： Karen Duffy , Paul Benni , George Brocksieper
发明人： Karen Duffy , Paul Benni , George Brocksieper
IPC分类号： G01J5/02
CPC分类号： A61B5/14552 , A61B5/14553 , A61B5/6814 , A61B5/6831 , G01N21/359 , G01N21/49
摘要： A near infrared spectrophotometric (NIRS) sensor apparatus is provided that includes at least one NIRS sensor and a mounting device. The sensor has at least one light source, at least one light detector, and a flexible pad. The light source and the light detector are mounted on the flexible pad, which flexible pad has a peripheral edge that extends around the entire periphery of the pad. The light source and light detectors are configured for connection to an electro-optical cable. The mounting device is operable to secure the sensor to a subject, which mounting device is sized to cover the sensor and contact the subject around the entire peripheral edge of the pad. The mounting device includes a light barrier that at least substantially blocks light from passing through the mounting device.
摘要翻译：提供了一种近红外分光光度计（NIRS）传感器装置，其包括至少一个NIRS传感器和安装装置。传感器具有至少一个光源，至少一个光检测器和柔性垫。光源和光检测器安装在柔性垫上，该柔性垫具有围绕垫的整个周边延伸的周边边缘。光源和光检测器被配置为连接到电光缆。安装装置可操作以将传感器固定到被检体，该安装装置的尺寸被设计成覆盖传感器并且将物体接触围绕垫的整个周边边缘。安装装置包括至少基本上阻挡光通过安装装置的光屏障。

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