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1. 发明授权

US07534336B2 Continuous flow particle concentrator 有权
标题翻译：连续流粒子集中器
公开(公告)号：US07534336B2
公开(公告)日：2009-05-19
申请号：US10838570
申请日：2004-05-04
申请人： Armin R. Volkel , Meng H. Lean , H Ben Hsieh , Jurgen H Daniel
发明人： Armin R. Volkel , Meng H. Lean , H Ben Hsieh , Jurgen H Daniel
IPC分类号： G01N27/453
CPC分类号： B03C5/028 , G01N2030/0035
摘要： An apparatus for extracting and concentrating bioagents within a continuously flowing fluid medium includes a flow channel fluid inlet, in which bioagents are concentrated from three dimensions to a two-dimensional transport layer in a preconcentration area. Traveling wave grids cause the preconcentrated bioagents to migrate to one side of the flow channel and then to an extraction port. Each of the traveling wave grids includes a substrate, a collection of closely spaced and parallel electrically conductive electrodes extending across said substrate, and a collection of buses providing electrical communication with the collection of conductive electrodes. A voltage controller provides a multiphase electrical signal to the collection of buses and electrodes of the traveling wave grids. Fluid exits through an outlet port.
摘要翻译：用于在连续流动的流体介质中提取和浓缩生物体的装置包括流动通道流体入口，其中生物体从三维集中到预浓缩区域中的二维输送层。旅行波谷使预浓缩的生物标签迁移到流动通道的一侧，然后迁移到提取口。每个行波波谷包括基板，跨越所述基板的紧密间隔且平行的导电电极的集合，以及提供与导电电极集合电连通的总线的集合。电压控制器提供多相电信号，用于收集行波网格的总线和电极。流体通过出口排出。

2. 发明授权

US07491307B2 Portable bioagent concentrator 失效
标题翻译：便携式生物聚焦器
公开(公告)号：US07491307B2
公开(公告)日：2009-02-17
申请号：US10838937
申请日：2004-05-04
申请人： H Ben Hsieh , Meng H. Lean , Bryan T. Preas , Armin R. Volkel
发明人： H Ben Hsieh , Meng H. Lean , Bryan T. Preas , Armin R. Volkel
IPC分类号： G01N27/453
CPC分类号： G01N27/453
摘要： A portable apparatus for extracting and concentrating bioagents within a fluid medium includes a container with sample solution inlet port and traveling wave grids patterned on surfaces of the container. The traveling wave grids cause bioagents to migrate to a specified surface within the container and then to an extraction port. The traveling wave grids include a substrate, across which extend a collection of closely spaced and parallel electrically conductive electrodes, and a collection of buses providing electrical communication with the collection of conductive electrodes. A voltage controller provides a multiphase electrical signal to the collection of buses and electrodes of the traveling wave grids.
摘要翻译：用于在流体介质中提取和浓缩生物体的便携式设备包括具有样品溶液入口的容器和在容器表面上图案化的行波网格。行波网格使生物体迁移到容器内的指定表面，然后迁移到提取口。行波网格包括基板，跨越其延伸紧密间隔且平行的导电电极的集合，以及提供与导电电极集合电连通的总线的集合。电压控制器提供多相电信号，用于收集行波网格的总线和电极。

3. 发明授权

US07268868B2 Anti-resonant waveguide sensors 有权
标题翻译：反谐振波导传感器
公开(公告)号：US07268868B2
公开(公告)日：2007-09-11
申请号：US10976434
申请日：2004-10-29
申请人： Peter Kiesel , Oliver H. Wolst , Michael A. Kneissl , H Ben Hsieh
发明人： Peter Kiesel , Oliver H. Wolst , Michael A. Kneissl , H Ben Hsieh
IPC分类号： G01J3/44 , G01J3/30 , G01N21/64 , G01N21/65
CPC分类号： G02B6/10 , G01N21/03 , G01N21/0303 , G01N21/33 , G01N21/35 , G01N21/3577 , G01N21/64 , G01N21/65 , G01N2021/651 , G02B6/032 , G02B6/34
摘要： An improved method of analyzing target analytes in a sample is described. The method is based on anti-resonant guided optical waveguides which enables a strongly improved light-target interaction since the light can be guided within the target-containing medium. The light-target interaction can be monitored by many different means to determine characteristics of the target analyte. The anti-resonant waveguide concept is suitable for a large variety of characterization methods and combinations of them, since it is relatively unaffected by changes to both wavelength and film thickness.
摘要翻译：描述了一种分析样品中目标分析物的改进方法。该方法基于反谐振导向光波导，其能够实现强烈改善的光 - 目标相互作用，因为可以在含靶介质的介质内引导光。光靶相互作用可以通过许多不同的手段来监测，以确定目标分析物的特征。反谐振波导概念适用于各种表征方法及其组合，因为它相对不受波长和膜厚度变化的影响。

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