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1. 发明授权

US07194117B2 System and method for performing a three-dimensional virtual examination of objects, such as internal organs 有权
标题翻译：对物体（如内脏）进行三维虚拟检查的系统和方法
公开(公告)号：US07194117B2
公开(公告)日：2007-03-20
申请号：US09777120
申请日：2001-02-05
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
IPC分类号： G06K9/00
CPC分类号： A61B5/055 , A61B5/726 , A61B6/032 , A61B8/483 , G06T7/11 , G06T15/08 , G06T19/00 , G06T2207/10072 , G06T2207/30028 , G06T2207/30084 , G06T2207/30172 , G06T2210/41 , G06T2219/028 , G06T2219/2004 , G09B23/28
摘要： Methods for generating a three-dimensional visualization image of an object, such as an internal organ, using volume visualization techniques are provided. The techniques include a multi-scan imaging method; a multi-resolution imaging method; and a method for generating a skeleton of a complex three dimension object. The applications include virtual cystoscopy, virtual laryngoscopy, virtual angiography, among others.
摘要翻译：提供了使用体积可视化技术来生成诸如内部器官的对象的三维可视化图像的方法。该技术包括多扫描成像方法; 多分辨率成像方法; 以及用于生成复杂三维物体的骨架的方法。应用包括虚拟膀胱镜检查，虚拟喉镜检查，虚拟血管造影等。

2. 发明授权

US07486811B2 System and method for performing a three-dimensional virtual examination of objects, such as internal organs 有权
公开(公告)号：US07486811B2
公开(公告)日：2009-02-03
申请号：US11613297
申请日：2006-12-20
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T17/00 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/64 , G06T15/08 , G06T19/00 , G06T2207/10081 , G06T2207/20044 , G06T2207/20064 , G06T2207/30028 , G06T2207/30101
摘要： Methods for generating a three-dimensional visualization image of an object, such as an internal organ, using volume visualization techniques are provided. The techniques include a multi-scan imaging method; a multi-resolution imaging method; and a method for generating a skeleton of a complex three dimension object. The applications include virtual cystoscopy, virtual laryngoscopy, virtual angiography, among others.

3. 发明授权

US07477768B2 System and method for performing a three-dimensional virtual examination of objects, such as internal organs 有权
公开(公告)号：US07477768B2
公开(公告)日：2009-01-13
申请号：US11613306
申请日：2006-12-20
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
IPC分类号： G06K9/00
CPC分类号： G06T17/00 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/64 , G06T15/08 , G06T19/00 , G06T2207/10081 , G06T2207/20044 , G06T2207/20064 , G06T2207/30028 , G06T2207/30101
摘要： Methods for generating a three-dimensional visualization image of an object, such as an internal organ, using volume visualization techniques are provided. The techniques include a multi-scan imaging method; a multi-resolution imaging method; and a method for generating a skeleton of a complex three dimension object. The applications include virtual cystoscopy, virtual laryngoscopy, virtual angiography, among others.

4. 发明授权

US07474776B2 System and method for performing a three-dimensional virtual examination of objects, such as internal organs 有权
标题翻译：对物体（如内脏）进行三维虚拟检查的系统和方法
公开(公告)号：US07474776B2
公开(公告)日：2009-01-06
申请号：US11613283
申请日：2006-12-20
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
IPC分类号： G06K9/00
CPC分类号： A61B5/055 , A61B5/726 , A61B6/032 , A61B8/483 , G06T7/11 , G06T15/08 , G06T19/00 , G06T2207/10072 , G06T2207/30028 , G06T2207/30084 , G06T2207/30172 , G06T2210/41 , G06T2219/028 , G06T2219/2004 , G09B23/28
摘要： Methods for generating a three-dimensional visualization image of an object, such as an internal organ, using volume visualization techniques are provided. The techniques include a multi-scan imaging method; a multi-resolution imaging method; and a method for generating a skeleton of a complex three dimension object. The applications include virtual cystoscopy, virtual laryngoscopy, virtual angiography, among others.
摘要翻译：提供了使用体积可视化技术来生成诸如内部器官的对象的三维可视化图像的方法。该技术包括多扫描成像方法; 多分辨率成像方法; 以及用于生成复杂三维物体的骨架的方法。应用包括虚拟膀胱镜检查，虚拟喉镜检查，虚拟血管造影等。

5. 发明授权

US07630750B2 Computer aided treatment planning 有权
标题翻译：计算机辅助治疗计划
公开(公告)号：US07630750B2
公开(公告)日：2009-12-08
申请号：US10182217
申请日：2001-02-05
申请人： Zhengrong Liang , Bin Li , Dongqing Chen , Eric E. Smouha , Clemente T. Roque , Arie E. Kaufman , Mark R. Wax , Kevin Kreeger
发明人： Zhengrong Liang , Bin Li , Dongqing Chen , Eric E. Smouha , Clemente T. Roque , Arie E. Kaufman , Mark R. Wax , Kevin Kreeger
IPC分类号： A61B5/05
CPC分类号： G06T19/003 , A61B34/10 , A61B90/36 , G06F19/00 , G06F19/321 , G06F19/3481 , G06T15/08 , G06T2210/41 , G16H50/50 , Y10S128/922
摘要： A method of computer aided treatment planning is performed by generating and manipulating a three dimensional (3D) image of a region which includes at least one anatomical structure for which treatment, such as surgery, biopsy, tissue component analysis, prosthesis implantation, radiation, chemotherapy and the like, is contemplated. A virtual intervention, which simulates at least a portion of the contemplated treatment, is performed in the 3D image. The user can then determine the effect of the intervention and interactively modify the intervention for improved treatment results. Preferably, a warning is automatically provided if the intervention poses a risk of detrimental effect. The user can navigate through the contemplated region in the 3D image and assess the results. The treatment plans can be saved for comparison and post treatment evaluation.
摘要翻译：计算机辅助治疗计划的方法通过生成和操纵包括至少一个解剖结构的区域的三维（3D）图像来进行，所述解剖结构例如手术，活组织检查，组织成分分析，假体植入，放射，化疗等等。在3D图像中执行模拟预期治疗的至少一部分的虚拟介入。然后，用户可以确定干预的效果并交互地修改干预以改善治疗结果。优选地，如果干预造成有害影响的风险，则自动提供警告。用户可以浏览3D图像中的预期区域并评估结果。治疗计划可以节省进行比较和治疗后评估。

6. 发明授权

US06343936B1 System and method for performing a three-dimensional virtual examination, navigation and visualization 有权
标题翻译：用于执行三维虚拟检查，导航和可视化的系统和方法
公开(公告)号：US06343936B1
公开(公告)日：2002-02-05
申请号：US09493559
申请日：2000-01-28
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen
IPC分类号： G09B2328
CPC分类号： G06T19/003 , G06K9/209 , G06K9/38 , G06K2209/05 , G06T15/08 , G06T2210/28 , G06T2210/41 , Y10S128/92 , Y10S128/922 , Y10S345/952 , Y10S345/959
摘要： A system and method for generating a three-dimensional visualization image of an object such as an organ using volume visualization techniques and exploring the image using a guided navigation system which allows the operator to travel along a flight path and to adjust the view to a particular portion of the image of interest in order, for example, to identify polyps, cysts or other abnormal features in the visualized organ. An electronic biopsy can also be performed on an identified growth or mass in the visualized object. Improved fly-path generation and volume rendering techniques provide enhanced navigation through, and examination of, a region of interest.
摘要翻译：一种用于使用体积可视化技术产生诸如器官的物体的三维可视化图像的系统和方法，并且使用导航系统探索图像，该导航系统允许操作者沿着飞行路径行进并且将视图调整到特定的例如，为了识别可视化器官中的息肉，囊肿或其他异常特征，感兴趣的图像的一部分。电子活检也可以对可视化物体中的识别生长或质量进行。改进的飞行路径生成和体积渲染技术通过和感兴趣的区域提供了增强的导航。

7. 发明授权

US07356367B2 Computer aided treatment planning and visualization with image registration and fusion 失效
标题翻译：计算机辅助治疗计划和可视化与图像配准和融合
公开(公告)号：US07356367B2
公开(公告)日：2008-04-08
申请号：US10297349
申请日：2001-06-06
申请人： Zhengrong Liang , Dongqing Chen , Bin Li , Clemente T. Roque , Eric E. Smouha , Arie E. Kaufman , Mark R. Wax , Kevin Kreeger
发明人： Zhengrong Liang , Dongqing Chen , Bin Li , Clemente T. Roque , Eric E. Smouha , Arie E. Kaufman , Mark R. Wax , Kevin Kreeger
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B5/726 , A61B90/36 , A61B2090/364 , G06F19/00
摘要： A computer based system and method of visualizing a region using multiple image data sets is provided. The method includes acquiring first volumetric image data of a region and acquiring at least second volumetric image data of the region. The first image data is generally selected such that the structural features of the region are readily visualized. At least one control point is determined in the region using an identifiable structural characteristic discernable in the first volumetric image data. The at least one control point is also located in the at least second image data of the region such that the first image data and the at least second image data can be registered to one another using the at least one control point. Once the image data sets are registered, the registered first image data and at least second image data can be fused into a common display data set. The multiple image data sets have different and complimentary information to differentiate the structures and the functions in the region such that image segmentation algorithms and user interactive editing tools can be applied to obtain 3d spatial relations of the components in the region. Methods to correct spatial inhomogeneity in MR image data is also provided.
摘要翻译：提供了一种基于计算机的系统和使用多个图像数据集可视化区域的方法。该方法包括获取区域的第一体积图像数据并且获取该区域的至少第二体积图像数据。通常选择第一图像数据，使得该区域的结构特征容易可视化。使用在第一体积图像数据中可识别的可识别的结构特征在该区域中确定至少一个控制点。至少一个控制点也位于区域的至少第二图像数据中，使得可以使用至少一个控制点将第一图像数据和至少第二图像数据彼此对准。一旦注册了图像数据集，就可将注册的第一图像数据和至少第二图像数据融合到公共显示数据集中。多个图像数据集具有不同的和互补的信息以区分该区域中的结构和功能，使得可以应用图像分割算法和用户交互式编辑工具来获得该区域中的部件的3d空间关系。还提供了校正MR图像数据的空间不均匀性的方法。

8. 发明授权

US07574024B2 Centerline and tree branch skeleton determination for virtual objects 有权
标题翻译：虚拟对象的中心线和树枝骨架确定
公开(公告)号：US07574024B2
公开(公告)日：2009-08-11
申请号：US10380211
申请日：2001-10-02
申请人： Ingmar Bitter , Ming Wan , Arie E. Kaufman , Frank Dachille , Kevin Kreeger , Zhengrong Liang , Mark R. Wax
发明人： Ingmar Bitter , Ming Wan , Arie E. Kaufman , Frank Dachille , Kevin Kreeger , Zhengrong Liang , Mark R. Wax
IPC分类号： G06K9/00
CPC分类号： G06T19/20 , G06T7/12 , G06T7/62 , G06T7/64 , G06T15/08 , G06T15/10 , G06T2200/04 , G06T2207/10072 , G06T2207/20044 , G06T2207/20132 , G06T2207/30028 , G06T2207/30061 , G06T2207/30172 , G06T2210/41 , G06T2219/028 , G06T2219/2012
摘要： In accordance with the present invention, a method for determining a centerline through a region of interest in a 3D image dataset is provided. The method includes identifying the boundaries of the region of interest and identifying the endpoints of the region of interest. For those points within the boundaries, a penalty value which is a function of the proximity of the point to a boundary is determined. A centerline is then identified by the path connecting the endpoints which has the minimum penalized distance wherein the penalized distance reflects the actual accumulated pathlength and the penalties associated with the points along the path. From the centerline, branches of a complete skeleton can be established by determining branch endpoints and then finding the minimum penalized distance from each endpoint the centerline or another intersecting branch.
摘要翻译：根据本发明，提供了一种通过3D图像数据集中的感兴趣区域确定中心线的方法。该方法包括识别感兴趣区域的边界并识别感兴趣区域的端点。对于边界内的那些点，确定作为点到边界的接近度的函数的惩罚值。然后通过连接具有最小惩罚距离的端点的路径来识别中心线，其中惩罚距离反映实际累积路径长度和与沿着路径的点相关联的惩罚。从中心线，可以通过确定分支端点，然后从中心线或另一个相交分支的每个端点找到最小惩罚距离来建立完整骨架的分支。

9. 发明授权

US07148887B2 System and method for performing a three-dimensional virtual segmentation and examination with optical texture mapping 有权
公开(公告)号：US07148887B2
公开(公告)日：2006-12-12
申请号：US09974548
申请日：2001-10-10
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongquing Chen
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongquing Chen
IPC分类号： G06T15/00
CPC分类号： G06T15/08 , G06K9/209 , G06K9/38 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T15/04 , G06T19/20 , G06T2207/10081 , G06T2207/20156 , G06T2207/30032 , G06T2210/28 , G06T2210/41 , G06T2219/2021
摘要： A system and method for generating a three-dimensional visualization image of an object such as an organ using volume visualization techniques and exploring the image using a guided navigation system which allows the operator to travel along a flight path and to adjust the view to a particular portion of the image of interest in order, for example, to identify polyps, cysts or other abnormal features in the visualized organ. An electronic biopsy can also be performed on an identified growth or mass in the visualized object. Virtual colonoscopy can be enhanced by electronically removing residual stool, fluid and non-colonic tissue from the image of the colon, by employing bowel preparation followed by image segmentation operations. Methods are also employed for virtually expanding regions of colon collapse using image segmentation results.

10. 发明授权

US06331116B1 System and method for performing a three-dimensional virtual segmentation and examination 有权
标题翻译：用于执行三维虚拟分割和检查的系统和方法
公开(公告)号：US06331116B1
公开(公告)日：2001-12-18
申请号：US09343012
申请日：1999-06-29
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongquing Chen
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongquing Chen
IPC分类号： G09B2328
CPC分类号： G06T15/08 , G06K9/209 , G06K9/38 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T15/04 , G06T19/20 , G06T2207/10081 , G06T2207/20156 , G06T2207/30032 , G06T2210/28 , G06T2210/41 , G06T2219/2021
摘要： A system and method for generating a three-dimensional visualization image of an object such as an organ using volume visualization techniques and exploring the image using a guided navigation system which allows the operator to travel along a flight path and to adjust the view to a particular portion of the image of interest in order, for example, to identify polyps, cysts or other abnormal features in the visualized organ. An electronic biopsy can also be performed on an identified growth or mass in the visualized object. Virtual colonoscopy can be enhanced by electronically removing residual stool, fluid and non-colonic tissue from the image of the colon, by employing bowel preparation followed by image segmentation operations. Methods are also employed for virtually expanding regions of colon collapse using image segmentation results.
摘要翻译：一种用于使用体积可视化技术产生诸如器官的物体的三维可视化图像的系统和方法，并且使用导航系统探索图像，该导航系统允许操作者沿着飞行路径行进并且将视图调整到特定的例如，为了识别可视化器官中的息肉，囊肿或其他异常特征，感兴趣的图像的一部分。电子活检也可以对可视化物体中的识别生长或质量进行。通过使用排便，然后进行图像分割操作，可以通过电子方式从结肠图像中去除残留的粪便，流体和非结肠组织来增强虚拟结肠镜检查。方法也用于使用图像分割结果实际扩张结肠崩溃区域。

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