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    • 1. 发明授权
    • Devices for carrying out chemical and clinical tests, and their use
    • 用于进行化学和临床测试的设备及其使用
    • US4742011A
    • 1988-05-03
    • US740918
    • 1985-05-30
    • Anthony BlakeJohn ColeyRonald Smith
    • Anthony BlakeJohn ColeyRonald Smith
    • G01N33/493B01L3/00C12M1/34G01N33/48G01N33/53G01N33/543B01L9/00G01N33/76
    • B01L3/502G01N33/5302G01N33/54366Y10S436/807Y10S436/81Y10S436/818
    • A device for carrying out chemical or clinical testing of a liquid sample, for example a urine sample, by a specific binding assay, said device comprising a test component (2) which has a sensitized solid surface (2a) carrying an immobilized component of a specific binding pair relevant to the assay, and a handling piece (1), and characterized in that the test component (2) bearing the sensitized surface (2a) is removably mounted in spaced relationship with a removably mounted accessory component (4) carrying an accessory solid surface (5), and in that there is a space (4a) between the sensitized surface (2a) and the removable accessory component (4) to act as a container for sample liquid, so that when the device is contacted with a sample liquid source or immersed in liquid which is to provide the test sample, liquid of the sample can enter the space (4a) to contact the sensitized surface (2a), and the accessory surface (5) acts to retain and contain sample liquid in contact with the sensitized surface (2a) even after removal of the device from further contact with or immersion in the source of sample liquid, and in that the test component (2) is so formed that after removal of the removable accessory component (4) the sensitized surface (2a) is left exposed and accessible to further treatment liquid such as washing liquid and/or reagents.
    • PCT No.PCT / GB85 / 00102 Sec。 371日期1985年5月30日第 102(e)日期1985年5月30日PCT提交1985年3月15日PCT公布。 公开号WO85 / 04255 1985年9月26日,一种用于通过特异性结合测定对液体样品例如尿样进行化学或临床测试的装置,所述装置包括具有敏化固体表面(2a)的测试组分(2) )和操作件(1),其特征在于,承载感光表面(2a)的测试部件(2)可拆卸地安装成与可拆卸地安装在一起的间隔开的关系 附着固体表面(5)的辅助部件(4),并且在致敏表面(2a)和可拆卸附件(4)之间存在空间(4a),以用作样品液体的容器,使得 当设备与样品液体源接触或浸入要提供测试样品的液体中时,样品的液体可以进入空间(4a)以接触致敏表面(2a),并且附件表面(5)起作用 保留并容纳样品液体 即使在将装置从样品液体进一步接触或浸没在样品液体源中之后,也与致敏表面(2a)接触,并且测试部件(2)被形成为在去除可移除的附件部件(4)之后 )致敏表面(2a)被暴露并可进一步处理液体如洗涤液体和/或试剂。
    • 5. 发明申请
    • ENHANCED LIFETIME ILLUMINATOR
    • 增强型寿命照明灯
    • US20080086116A1
    • 2008-04-10
    • US11867932
    • 2007-10-05
    • Ronald SmithJaime CanedoMark Buczek
    • Ronald SmithJaime CanedoMark Buczek
    • A61B18/18
    • A61B3/0008A61B90/30A61B2090/306A61F9/007
    • An ophthalmic illuminator is disclosed, one embodiment comprising: an illumination source, wherein the illumination source produces an arc; a lens, such as a condensing lens, for focusing light produced by the illumination source arc; and an optical fiber for carrying the focused light to a surgical site, such as an eye. The illumination source is positioned offset from a longitudinal axis of the optical fiber to compensate for shifting of the illumination source arc over time. The offset position can be such that the illumination source is positioned in a vertically offset position from the longitudinal axis of the optical fiber. The longitudinal axis corresponds to the optical path axis of the optical fiber. The ophthalmic illuminator can further comprise a reflector for reflecting the light produced by the illumination source arc, wherein the reflector is positioned offset from the illumination source to decrease the rate of erosion of an illumination source cathode.
    • 公开了一种眼科照明器,一个实施例包括:照明源,其中照明源产生电弧; 用于聚焦由照明源电弧产生的光的诸如聚光透镜的透镜; 以及用于将聚焦光携带到诸如眼睛的手术部位的光纤。 照明源定位成偏离光纤的纵向轴线,以补偿照明源电弧随时间的移动。 偏移位置可以使得照明源位于离光纤的纵向轴线的垂直偏移位置。 纵轴对应于光纤的光路轴。 眼用照明器还可以包括用于反射由照明源弧产生的光的反射器,其中反射器定位成偏离照明源,以降低照明源阴极的侵蚀速率。
    • 7. 发明申请
    • Surgical variable-angle illuminator
    • 手术可变角度照明器
    • US20070100326A1
    • 2007-05-03
    • US11590011
    • 2006-10-31
    • Ronald Smith
    • Ronald Smith
    • A61B18/18
    • A61F9/007A61B2090/306
    • A variable-angle, wide-angle illuminator is disclosed, one embodiment being a small-gauge, variable-angle illumination surgical system comprising: a light source for providing a light beam; an optical cable, optically coupled to the light source for receiving and transmitting the light beam; a handpiece, operably coupled to the optical cable; an optical fiber, operably coupled to the handpiece, wherein the optical fiber is optically coupled to the optical cable to receive and transmit the light beam; an optical assembly, optically coupled to a distal end of the optical fiber, for receiving the light beam and providing the light beam to illuminate a surgical field; and a cannula, operably coupled to the handpiece and optical assembly, for housing and directing the optical assembly to illuminate a selected area, such as a surgical site. The optical assembly can comprise, for example, a fiber/polymer-dispersed-liquid-crystal (“PDLC”) diffuser optically coupled to an optical needle or a nested compound parabolic concentrator (“CPC”) cone. In the PDLC diffuser/needle embodiment, the fiber can be a standard endo-illuminator optical fiber with 0.50 NA or similar value. The light beam from the light source is emitted from the distal end of the optical fiber and provided to the PDLC diffuser for further transmission. The degree of diffusion of the light beam at the PDLC diffuser can be electrically controlled and can be varied from no diffusion to very high degree of diffusion. After passing through the PDLC diffuser, the light beam is provided to a needle or fiber, such as a glass needle or fiber, that transmits the light beam to the surgical site in the eye.
    • 公开了一种可变角度的广角照明器,一个实施例是小规模可变角度照明手术系统,包括:用于提供光束的光源; 光缆,光学耦合到光源,用于接收和传输光束; 可操作地耦合到所述光缆的手持件; 光纤,其可操作地耦合到所述手持件,其中所述光纤光耦合到所述光缆以接收和传输所述光束; 光学组件,其光耦合到所述光纤的远端,用于接收所述光束并提供所述光束以照射外科视野; 以及可操作地联接到所述手持件和光学组件的插管,用于容纳和引导所述光学组件以照亮所选择的区域,例如外科手术部位。 光学组件可以包括例如光学耦合到光学针或嵌套复合抛物面聚光器(“CPC”)锥的纤维/聚合物分散液晶(“PDLC”)扩散器。 在PDLC扩散器/针实施例中,光纤可以是具有0.50NA或相似值的标准内照射光纤。 来自光源的光束从光纤的远端发射并提供给PDLC扩散器用于进一步传输。 在PDLC扩散器处的光束的扩散程度可以被电控制,并且可以从不扩散到非常高的扩散程度来改变。 在通过PDLC扩散器之后,将光束提供给将光束传输到眼睛中的手术部位的针或纤维,例如玻璃针或纤维。
    • 8. 发明申请
    • System and method for calibrating a tod clock
    • 校准时钟的系统和方法
    • US20070058491A1
    • 2007-03-15
    • US11223642
    • 2005-09-09
    • Dennis DahlenDavid ElkoRonald SmithLi Zhang
    • Dennis DahlenDavid ElkoRonald SmithLi Zhang
    • G04C13/00
    • G06F1/14G04G7/00H04J3/0644H04J3/0685H04L69/28
    • A system, method and computer program product for calibrating a Time Of Day (TOD)-clock in a computing system node provided in a multi-node network. The network comprises an infrastructure of computing devices each having a physical clock providing a time base for executing operations that is stepped to a common oscillator. The system implements steps for obtaining samples of timing values of a computing device in the network, the values including a physical clock value maintained at that device and a TOD-offset value; computing an oscillator skew value from the samples; setting a fine steering rate value as equal to the opposite of the computed oscillator skew value; and, utilizing the fine steering rate value to adjust the physical clock value and correct for potential oscillator skew errors occurring in the oscillator crystal at the computing device.
    • 一种用于在多节点网络中提供的计算系统节点中校准时钟(TOD)时钟的系统,方法和计算机程序产品。 该网络包括计算设备的基础设施,每个设备具有提供用于执行步进到公共振荡器的操作的时基的物理时钟。 该系统实现用于获得网络中计算设备的定时值的采样的步骤,该值包括在该设备处保持的物理时钟值和TOD偏移值; 从样本计算振荡器偏移值; 将精细的转向率值设置为等于所计算的振荡器偏移值的相反; 并且利用精细转向率值来调整物理时钟值并校正在计算装置处发生在振荡器晶体中的潜在的振荡器偏斜误差。
    • 9. 发明申请
    • Harmonic drive motor with flex-spline interlock
    • 谐波驱动电机带有曲面花键互锁
    • US20060283289A1
    • 2006-12-21
    • US11450883
    • 2006-06-09
    • Thomas BaudendistelRonald SmithHarald Klode
    • Thomas BaudendistelRonald SmithHarald Klode
    • F16H35/00
    • F16H49/001H02K41/06Y10T74/19
    • A harmonic drive motor includes a first annular member, concentric second and third members, and a device for flexing the first annular member. The first annular member has a longitudinal axis and is flexible. The second member is relatively rigid and is substantially coaxially aligned externally of the first annular member, and the third member is relatively rigid and is substantially coaxially aligned internally of the first annular member. One of the second and third members is rotatable about the longitudinal axis and the other is relatively non-rotatable. The flexing device flexes the first annular member into at least two spaced-apart points of contact with the inner diameter surface of the second member and into at least two spaced-apart points of contact with the outer diameter surface of the third member. The flexing device sequentially flexes the first annular member to rotate both sets of at least two points of contact about the longitudinal axis which effects relative rotation between the second and third members.
    • 谐波驱动马达包括第一环形构件,同心第二和第三构件,以及用于使第一环形构件弯曲的装置。 第一环形构件具有纵向轴线并且是柔性的。 第二构件相对刚性并且基本上同轴地对准于第一环形构件的外部,并且第三构件相对刚性并且在第一环形构件的内部基本上同轴地对准。 第二和第三构件中的一个可围绕纵向轴线旋转,而另一个相对不可旋转。 弯曲装置将第一环形构件弯曲成与第二构件的内径表面成至少两个间隔开的接触点并且与第三构件的外径表面接触的至少两个间隔开的点。 弯曲装置顺序地弯曲第一环形构件以使围绕纵向轴线的两组至少两个接触点旋转,这两个接触点影响第二和第三构件之间的相对旋转。
    • 10. 发明申请
    • High throughput endo-illuminator probe
    • 高通量内照明探头
    • US20060184162A1
    • 2006-08-17
    • US11354615
    • 2006-02-15
    • Ronald Smith
    • Ronald Smith
    • A61B18/18
    • A61F9/007A61B3/0008A61B90/36A61B2090/306
    • A high throughput endo-illuminator and illumination surgical system are disclosed. One embodiment of the high throughput endo-illumination surgical system comprises: a light source for providing a light beam; a proximal optical fiber, optically coupled to the light source for receiving and transmitting the light beam; a distal optical fiber, optically coupled to a distal end of the proximal optical fiber, for receiving the light beam and emitting the light beam to illuminate a surgical site, wherein the distal optical fiber comprises a tapered section having a proximal-end diameter larger than a distal-end diameter; a handpiece, operably coupled to the distal optical fiber; and a cannula, operably coupled to the handpiece, for housing and directing the distal optical fiber. The tapered section's proximal end diameter can be the same as the diameter of the proximal optical fiber, and can be, for example, a 20 gauge diameter. The tapered section's distal end diameter can be, for example, a 25 gauge compatible diameter. The cannula can be a 25 gauge inner-diameter cannula. The proximal optical fiber can preferably have an NA equal to or greater than the NA of the light source beam and the distal optical fiber preferably can have an NA greater than that of the proximal optical fiber and greater than that of the light source beam at any point in the distal optical fiber (since the light beam NA can increase as it travels through the tapered section).
    • 公开了一种高通量内照明器和照明手术系统。 高通量内照射手术系统的一个实施例包括:用于提供光束的光源; 近端光纤,光学耦合到光源,用于接收和传输光束; 远端光纤,光学耦合到近端光纤的远端,用于接收光束并发射光束以照射手术部位,其中远端光纤包括具有近端直径大于 远端直径; 可操作地耦合到远端光纤的手持件; 以及可操作地联接到所述手持件的插管,用于容纳和引导远端光纤。 锥形部的近端直径可以与近端光纤的直径相同,并且可以是例如20号的直径。 锥形部分的远端直径可以是例如25度相容的直径。 套管可以是25号内径插管。 近端光纤优选地具有等于或大于光源束的NA的NA,并且远端光纤优选地可以具有比近端光纤更大的NA,并且大于光源束的NA (因为光束NA可以随着其穿过锥形部分而增加)。