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1. 发明授权

US07862541B2 Catheter having a soft distal tip 有权
标题翻译：导管具有软的远端
公开(公告)号：US07862541B2
公开(公告)日：2011-01-04
申请号：US11766662
申请日：2007-06-21
申请人： Andrew Jeffrey , Louise Balfe , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula , Ib Joergensen , Randolf von Oepen
发明人： Andrew Jeffrey , Louise Balfe , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula , Ib Joergensen , Randolf von Oepen
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61F2/958 , A61M25/0069 , A61M25/1006 , A61M25/1027 , A61M25/104 , A61M2025/0081 , A61M2025/1093 , Y10T29/49826
摘要： The present invention relates to a catheter having a soft distal tip that can be manufactured at lower cost than catheters in the prior art. In one embodiment, the catheter is produced by coupling a soft sleeve to the distal end of a catheter tube. The sleeve may affixed to the catheter tube under temperature and pressure conditions that cause the proximal end of the sleeve to taper against the outer surface of the catheter tube, avoiding or minimizing discontinuities in the insertion profile of the catheter, and that also cause the inner wall of the sleeve to taper against the distal end of the catheter tube, avoiding or minimizing discontinuities in the lumen of the catheter.
摘要翻译：本发明涉及一种导管，其具有可以以比现有技术中的导管低的成本制造的软远侧末端。在一个实施例中，通过将软套管连接到导管管的远端来产生导管。套管可在温度和压力条件下固定到导管上，导致套筒的近端相对于导管的外表面逐渐变细，避免或最小化导管插入轮廓中的不连续性，并且还使得内套管的壁与导管管的远端成锥形，避免或最小化导管内腔的不连续性。

2. 发明申请

US20080004568A1 CATHETER HAVING A SOFT DISTAL TIP 有权
标题翻译：导管带有一个软的距离
公开(公告)号：US20080004568A1
公开(公告)日：2008-01-03
申请号：US11766662
申请日：2007-06-21
申请人： Andrew Jeffrey , Louise Balfe , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula , Ib Joergensen , Randolf von Oepen
发明人： Andrew Jeffrey , Louise Balfe , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula , Ib Joergensen , Randolf von Oepen
IPC分类号： A61M25/10
CPC分类号： A61M25/10 , A61F2/958 , A61M25/0069 , A61M25/1006 , A61M25/1027 , A61M25/104 , A61M2025/0081 , A61M2025/1093 , Y10T29/49826
摘要： The present invention relates to a catheter having a soft distal tip that can be manufactured at lower cost than catheters in the prior art. In one embodiment, the catheter is produced by coupling a soft sleeve to the distal end of a catheter tube. The sleeve may affixed to the catheter tube under temperature and pressure conditions that cause the proximal end of the sleeve to taper against the outer surface of the catheter tube, avoiding or minimizing discontinuities in the insertion profile of the catheter, and that also cause the inner wall of the sleeve to taper against the distal end of the catheter tube, avoiding or minimizing discontinuities in the lumen of the catheter.
摘要翻译：本发明涉及一种导管，其具有可以以比现有技术中的导管低的成本制造的软远侧末端。在一个实施例中，通过将软套管连接到导管管的远端来产生导管。套管可在温度和压力条件下固定到导管上，导致套筒的近端相对于导管的外表面逐渐变细，避免或最小化导管插入轮廓中的不连续性，并且还使得内套管的壁与导管管的远端成锥形，避免或最小化导管内腔的不连续性。

3. 发明申请

US20110172696A1 CATHETER HAVING A SOFT DISTAL TIP 审中-公开
标题翻译：导管带有一个软的距离
公开(公告)号：US20110172696A1
公开(公告)日：2011-07-14
申请号：US12983504
申请日：2011-01-03
申请人： Andrew Jeffrey , Louise Corcoran , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula , Ib Joergensen , Randolf von Oepen
发明人： Andrew Jeffrey , Louise Corcoran , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula , Ib Joergensen , Randolf von Oepen
IPC分类号： A61B17/22 , B23P17/04
CPC分类号： A61M25/10 , A61F2/958 , A61M25/0069 , A61M25/1006 , A61M25/1027 , A61M25/104 , A61M2025/0081 , A61M2025/1093 , Y10T29/49826
摘要： The present invention relates to a catheter having a soft distal tip that can be manufactured at lower cost than catheters in the prior art. In one embodiment, the catheter is produced by coupling a soft sleeve to the distal end of a catheter tube. The sleeve may affixed to the catheter tube under temperature and pressure conditions that cause the proximal end of the sleeve to taper against the outer surface of the catheter tube, avoiding or minimizing discontinuities in the insertion profile of the catheter, and that also cause the inner wall of the sleeve to taper against the distal end of the catheter tube, avoiding or minimizing discontinuities in the lumen of the catheter.
摘要翻译：本发明涉及一种导管，其具有可以以比现有技术中的导管低的成本制造的软远侧末端。在一个实施例中，通过将软套管连接到导管管的远端来产生导管。套管可在温度和压力条件下固定到导管上，导致套筒的近端相对于导管的外表面逐渐变细，避免或最小化导管插入轮廓中的不连续性，并且还使得内套管的壁与导管管的远端成锥形，避免或最小化导管内腔的不连续性。

4. 发明申请

US20070282367A1 Catheter having a soft distal tip 审中-公开
标题翻译：导管具有软的远端
公开(公告)号：US20070282367A1
公开(公告)日：2007-12-06
申请号：US11335931
申请日：2006-01-20
申请人： Andrew Jeffrey , Louise Balfe , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula
发明人： Andrew Jeffrey , Louise Balfe , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula
IPC分类号： A61M29/02
CPC分类号： A61M25/104 , A61F2/958 , A61M25/0045 , A61M25/0068 , A61M25/0069 , A61M25/008 , A61M25/1034 , A61M25/1036 , A61M2025/0034 , A61M2025/0039 , A61M2025/0081 , A61M2025/1093 , Y10T29/49879
摘要： The present invention relates to a catheter for POBA or stent delivery applications. More specifically, the present invention relates to a balloon catheter having a soft distal tip member and methods for manufacturing the same.
摘要翻译：本发明涉及用于POBA或支架递送应用的导管。更具体地说，本发明涉及一种具有软末端部件的球囊导管及其制造方法。

5. 发明申请

US20120203172A1 CATHETER HAVING A SOFT DISTAL TIP 审中-公开
标题翻译：导管带有一个软的距离
公开(公告)号：US20120203172A1
公开(公告)日：2012-08-09
申请号：US13349317
申请日：2012-01-12
申请人： Andrew Jeffrey , Louise Corcoran , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula
发明人： Andrew Jeffrey , Louise Corcoran , Lorcan Coffey , Arik Zucker , Kay Unzicker , Zdravkica Dzakula
IPC分类号： A61M25/10 , B23P17/04
CPC分类号： A61M25/104 , A61F2/958 , A61M25/0045 , A61M25/0068 , A61M25/0069 , A61M25/008 , A61M25/1034 , A61M25/1036 , A61M2025/0034 , A61M2025/0039 , A61M2025/0081 , A61M2025/1093 , Y10T29/49879
摘要： The present invention relates to a catheter for POBA or stent delivery applications. More specifically, the present invention relates to a balloon catheter having a soft distal tip member and methods for manufacturing the same.
摘要翻译：本发明涉及用于POBA或支架递送应用的导管。更具体地说，本发明涉及一种具有软末端部件的球囊导管及其制造方法。

6. 发明授权

US07967836B2 Dilatation balloon having reduced rigidity 有权
标题翻译：具有降低刚度的膨胀气球
公开(公告)号：US07967836B2
公开(公告)日：2011-06-28
申请号：US11455382
申请日：2006-06-19
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在弯曲通道中的更好的机动性。

7. 发明授权

US08292913B2 Method of reducing rigidity of angioplasty balloon sections 有权
标题翻译：降低血管成形术气囊截面刚度的方法
公开(公告)号：US08292913B2
公开(公告)日：2012-10-23
申请号：US13152081
申请日：2011-06-02
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在曲折通道中的更好的机动性。

8. 发明授权

US08986339B2 Method of reducing rigidity of angioplasty balloon sections 有权
标题翻译：降低血管成形术气囊截面刚度的方法
公开(公告)号：US08986339B2
公开(公告)日：2015-03-24
申请号：US13615096
申请日：2012-09-13
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00 , A61M25/10 , B23K26/40 , B29C59/16 , B29L31/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在曲折通道中的更好的机动性。

9. 发明申请

US20080097404A1 Catheter having markers to indicate rotational orientation 审中-公开
标题翻译：导管具有指示旋转取向的标记
公开(公告)号：US20080097404A1
公开(公告)日：2008-04-24
申请号：US11505697
申请日：2006-08-16
申请人： Travis R. Yribarren , Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Arik Zucker
发明人： Travis R. Yribarren , Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Arik Zucker
IPC分类号： A61M25/098 , A61M29/00 , A61F2/06 , A61F2/00
CPC分类号： A61M25/0108 , A61F2/856 , A61F2/954 , A61F2/958 , A61F2250/0098 , A61M2025/0008 , A61M2025/1079
摘要： Various improved catheter marking arrangements are described. In a first aspect of the invention, a first longitudinally extending radiopaque marker is positioned on the catheter. A second longitudinally extending radiopaque marker is positioned opposite the first marker at a rotational orientation that is approximately 180 degrees offset from the first marker. The second marker has a length that is sufficiently different from the first marker such that a surgeon utilizing the catheter in a surgical procedure would be able to readily differentiate the first and second markers in a fluoroscopic image based on their respective lengths in order to determine the rotational orientation of the catheter.In some embodiments, the catheter includes a lumen that has a side port that opens to a side of the catheter. The first marker is composed of a pair of axially aligned marker segments located on opposite ends of the side port. The length of the first longitudinal extending marker defined as an end-to-end length of the pair of axially aligned marker segments is longer than the length of the second marker. The markers may be formed from any suitable materials that can be clearly detected by an imaging system.
摘要翻译：描述了各种改进的导管标记装置。在本发明的第一方面，第一纵向延伸的不透射线的标记位于导管上。第二纵向延伸的不透射线标记物以与第一标记物大约180度偏离的旋转方向定位成与第一标记相对。第二标记具有与第一标记足够不同的长度，使得在外科手术中利用导管的外科医生能够根据它们各自的长度容易地区分荧光镜图像中的第一和第二标记，以便确定导管的旋转取向。在一些实施例中，导管包括具有向导管侧面开口的侧端口的内腔。第一标记由位于侧端口的相对端上的一对轴向对齐的标记段组成。被定义为一对轴向对准的标记段的端到端长度的第一纵向延伸标记的长度比第二标记的长度长。标记可以由能够被成像系统清楚地检测到的任何合适的材料形成。

10. 发明申请

US20090292241A1 BALLOON CATHETER 审中-公开
标题翻译：气球导管
公开(公告)号：US20090292241A1
公开(公告)日：2009-11-26
申请号：US12506066
申请日：2009-07-20
申请人： Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Travis R. Yribarren , Arik Zucker
发明人： Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Travis R. Yribarren , Arik Zucker
IPC分类号： A61M25/10 , B29C41/00
CPC分类号： A61F2/958 , A61M25/1002 , A61M25/1011 , A61M25/1027 , A61M25/1029 , A61M29/02 , A61M2025/0183 , A61M2025/1056 , A61M2025/107
摘要： A catheter arrangement is described that is arranged to permit a guide wire or other structure to be fed laterally from the region of an expandable working element. The catheter includes an elongate flexible tubular member and an inflatable structure carried by a distal portion of the flexible tubular member. The flexible tubular member has a guide wire lumen and at least one fluid supply lumen that is in fluid communication with the inflatable structure. The inflatable structure includes at least one, and preferably two, inflatable members (which may take the form of balloons). In the case of two inflatable members, the first and second inflatable members are radially spaced about the guide wire lumen such that at least one gap is formed between the inflatable members. With this arrangement, the distal end of a guide wire may be advanced through the guide lumen and out of a side opening such that the guide wire passes laterally between the first and second inflatable members. With such an arrangement, a guide wire passing out of the side opening in the region between the inflatable members can readily be directed into a second branch of a vessel bifurcation while the device is positioned in a first branch.
摘要翻译：描述了布置成允许导丝或其他结构从可扩张工作元件的区域横向地供给的导管装置。导管包括细长的柔性管状构件和由柔性管状构件的远侧部分承载的可膨胀结构。柔性管状构件具有导丝腔和与可充气结构流体连通的至少一个流体供应腔。可膨胀结构包括至少一个，优选两个可膨胀构件（其可以采取气球的形式）。在两个可膨胀构件的情况下，第一和第二可膨胀构件围绕导丝管腔径向隔开，使得在可膨胀构件之间形成至少一个间隙。通过这种布置，导丝的远端可以通过引导腔前进并且从侧开口排出，使得导丝横向地在第一和第二可膨胀构件之间通过。通过这样的布置，在可膨胀构件之间的区域中的侧开口中的引导线可以容易地被引导到容器分叉的第二分支中，同时装置位于第一分支中。

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