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1. 发明授权

US09662368B2 Formulation comprising whey protein and hydrolysates for improving muscle recovery 有权
公开(公告)号：US09662368B2
公开(公告)日：2017-05-30
申请号：US12304356
申请日：2007-06-15
申请人： Michelle Rowney , Andrew Brown , Yu Pan , Jonathan David Buckley
发明人： Michelle Rowney , Andrew Brown , Yu Pan , Jonathan David Buckley
IPC分类号： A61K38/18 , A61K38/01 , A23L33/18 , A23L33/19
CPC分类号： A61K38/018 , A23L33/18 , A23L33/19
摘要： The present invention relates to a formulation comprising whey protein or a hydrolysate of whey protein, which formulation is capable of inhibiting the expression of TNFα in lipopolysaccharide-stimulated macrophages in vitro. Also provided are uses of the formulation for attenuating a reduction in muscle function which results from muscle damage and/or for enhancing recovery from muscle damage and/or for enhancing the force generating capacity of muscle and methods of making the formulation.

2. 发明申请

US20100136172A1 PROCESS FOR THE PREPARATION OF ANGIOGENIN 有权
标题翻译：制备血管生成素的方法
公开(公告)号：US20100136172A1
公开(公告)日：2010-06-03
申请号：US12447889
申请日：2007-11-09
申请人： Andrew Brown , Michelle Rowney , Peter Hobman , Matthew McDonagh , Angus Tester , Benjamin Cocks
发明人： Andrew Brown , Michelle Rowney , Peter Hobman , Matthew McDonagh , Angus Tester , Benjamin Cocks
IPC分类号： A23C9/146
CPC分类号： A23C9/146 , A23L33/18 , A23L33/19 , A61K35/20 , A61K38/00 , C07K14/515
摘要： The invention provides a process for the preparation of an angiogenin-enriched fraction from a milk product, the process comprising contacting the milk product with a cation exchange resin and eluting the angiogenin-enriched fraction from the cation exchange resin with a mobile phase. The invention also provides angiogenin-enriched fractions produced by process and food products, neutraceuticals and pharmaceutical comprising such angiogenin.
摘要翻译：本发明提供了一种从乳制品制备富含血管生成素的级分的方法，该方法包括使乳制品与阳离子交换树脂接触，并用流动相从阳离子交换树脂中洗脱含血管生成素的部分。本发明还提供了通过方法和食品产生的血管生成素富集级分，包含这种血管生成素的中性药物和药物。

3. 发明申请

US20090214567A1 Immunoglobulin Fraction and Process Therefor 有权
标题翻译：免疫球蛋白分数及其过程
公开(公告)号：US20090214567A1
公开(公告)日：2009-08-27
申请号：US11920198
申请日：2006-05-10
申请人： Andrew Brown , Peter Hobman , Richard Paine , Michelle Rowney
发明人： Andrew Brown , Peter Hobman , Richard Paine , Michelle Rowney
IPC分类号： A61K39/395
CPC分类号： C07K16/04 , A23C9/1465 , A23C21/00 , A23L33/19 , C07K16/065 , C07K2317/12
摘要： The invention relates to the production of compositions containing IgA for use as a food additive. More specifically, it relates to a process to prepare an IgA-enriched milk product extract composition and to such compositions.
摘要翻译：本发明涉及含有用作食品添加剂的IgA的组合物的生产。更具体地，本发明涉及一种制备富含IgA的乳制品提取物组合物和这种组合物的方法。

4. 发明授权

US08282927B2 Immunoglobulin fraction and process therefor 有权
$Immunoglobulin fraction and process therefor$
标题翻译：免疫球蛋白分数及其过程
公开(公告)号：US08282927B2
公开(公告)日：2012-10-09
申请号：US11920198
申请日：2006-05-10
申请人： Andrew Brown , Peter Hobman , Richard Paine , Michelle Rowney
发明人： Andrew Brown , Peter Hobman , Richard Paine , Michelle Rowney
IPC分类号： A61K39/00 , A61K35/20
CPC分类号： C07K16/04 , A23C9/1465 , A23C21/00 , A23L33/19 , C07K16/065 , C07K2317/12
摘要： The invention relates to the production of compositions containing IgA for use as a food additive. More specifically, it relates to a process to prepare an IgA-enriched milk product extract composition and to such compositions.
摘要翻译：本发明涉及含有用作食品添加剂的IgA的组合物的生产。更具体地，本发明涉及一种制备富含IgA的乳制品提取物组合物和这种组合物的方法。

5. 发明申请

US20110098254A1 COMPOSITIONS COMPRISING PHOSPHOLIPIDS 审中-公开
标题翻译：包含磷脂的组合物
公开(公告)号：US20110098254A1
公开(公告)日：2011-04-28
申请号：US12673300
申请日：2008-08-15
申请人： Andrew Brown , Michelle Rowney
发明人： Andrew Brown , Michelle Rowney
IPC分类号： A61K31/683 , A61K8/55 , A61P29/00 , A61P35/00 , A61P25/00 , C12P9/00 , A23C9/20 , A23C9/12 , A23C7/04
CPC分类号： A61K31/688 , A23C2240/05 , A23J3/343 , A23J7/00 , A23L33/115 , A23L33/19 , A23V2002/00 , A61K31/683 , A61K31/685 , A61K38/018 , A23V2200/308 , A23V2250/5424 , A23V2250/1846 , A23V2250/185 , A23V2250/1852 , A23V2250/1848 , A23V2200/322
摘要： The present invention provides compositions comprising phospholipids and particularly those comprising at least 40% phospholipid and at least 80% phospholipid as a percentage of total fat in the extract, comprising polyunsaturated and saturated phospholipids, in a ratio of saturated phospholipid to monounsaturated to polyunsaturated phospholipid of about 6:3:1 respectively, or comprising at least 40% phospholipid and less than 40% protein and methods for their production from dairy products.
摘要翻译：本发明提供包含磷脂的组合物，特别是包含至少40％磷脂和至少80％磷脂的提取物中包含多不饱和和饱和磷脂的总脂肪百分比的组合物，其以饱和磷脂与单不饱和至多不饱和磷脂的比例约6：3：1，或包含至少40％的磷脂和小于40％的蛋白质及其从乳制品生产的方法。

6. 发明授权

US08551547B2 Process for the preparation of angiogenin 有权
标题翻译：血管生成素的制备方法
公开(公告)号：US08551547B2
公开(公告)日：2013-10-08
申请号：US12447889
申请日：2007-11-09
申请人： Andrew Brown , Michelle Rowney , Peter Hobman , Matthew McDonagh , Angus Tester , Benjamin Cocks
发明人： Andrew Brown , Michelle Rowney , Peter Hobman , Matthew McDonagh , Angus Tester , Benjamin Cocks
IPC分类号： C12H1/04 , A23C9/12
CPC分类号： A23C9/146 , A23L33/18 , A23L33/19 , A61K35/20 , A61K38/00 , C07K14/515
摘要： The invention provides a process for the preparation of an angiogenin-enriched fraction from a milk product, the process comprising contacting the milk product with a cation exchange resin and eluting the angiogenin-enriched fraction from the cation exchange resin with a mobile phase. The invention also provides angiogenin-enriched fractions produced by process and food products, nutraceuticals and pharmaceutical comprising such angiogenin.
摘要翻译：本发明提供了一种从乳制品制备富含血管生成素的级分的方法，该方法包括使乳制品与阳离子交换树脂接触，并用流动相从阳离子交换树脂中洗脱含血管生成素的部分。本发明还提供由方法和食品，营养药物和包含这种血管生成素的药物产生的富含血管生成素的级分。

7. 发明申请

US20090298767A1 FORMULATION COMPRISING WHEY PROTEIN AND HYDROLYSATES FOR IMPROVING MUSCLE RECOVERY 有权
标题翻译：包含WHEY蛋白质和水解物质的改善肌肉恢复的配方
公开(公告)号：US20090298767A1
公开(公告)日：2009-12-03
申请号：US12304356
申请日：2007-06-15
申请人： Michelle Rowney , Andrew Brown , Yu Pan , Jonathan David Buckley
发明人： Michelle Rowney , Andrew Brown , Yu Pan , Jonathan David Buckley
IPC分类号： A61K38/00 , A23J1/00
CPC分类号： A61K38/018 , A23L33/18 , A23L33/19
摘要： The present invention relates to a formulation comprising whey protein or a hydrolysate of whey protein, which formulation is capable of inhibiting the expression of TNFα in lipopolysaccharide-stimulated macrophages in vitro. Also provided are uses of the formulation for attenuating a reduction in muscle function which results from muscle damage and/or for enhancing recovery from muscle damage and/or for enhancing the force generating capacity of muscle and methods of making the formulation.
摘要翻译：本发明涉及包含乳清蛋白或乳清蛋白的水解产物的制剂，该制剂能够在体外抑制脂多糖刺激的巨噬细胞中TNFα的表达。还提供了用于减轻由肌肉损伤引起的肌肉功能降低和/或增强肌肉损伤恢复和/或增强肌肉的力产生能力和制备制剂的方法的用途。

8. 发明申请

US20190200127A1 Speaker Syncronizing System 审中-公开
公开(公告)号：US20190200127A1
公开(公告)日：2019-06-27
申请号：US15855166
申请日：2017-12-27
申请人： Andrew Brown , Anthony Mulder
发明人： Andrew Brown , Anthony Mulder
IPC分类号： H04R3/12 , G06F3/16
CPC分类号： H04R3/12 , G06F3/165 , H04R2420/07
摘要： A speaker synchronizing system for pairing multiple speakers to a single electronic device includes a housing that has a front wall, a back wall and a perimeter wall that is attached to and extends between the front wall and the back wall. A plurality of speakers is included wherein each of the speakers is positioned remote of the housing. An extrinsic electronic device is positioned remote of the housing and has an audio file stored thereon. A communication unit is mounted in the housing and is in electronic communication with each of the speakers and the extrinsic electronic device. The communication unit sends a signal that is discretely assigned to each of the speakers.

9. 发明授权

US09352775B2 Method for determining assist torque offset and system using same 有权
标题翻译：用于确定辅助扭矩偏移的方法和使用它的系统
公开(公告)号：US09352775B2
公开(公告)日：2016-05-31
申请号：US13537214
申请日：2012-06-29
申请人： Andrew Brown , Darrel Alan Recker
发明人： Andrew Brown , Darrel Alan Recker
IPC分类号： G06F17/00 , G06F19/00 , B62D6/00 , B62D15/02 , B62D5/00 , B62D5/04
CPC分类号： B62D6/008 , B62D5/008 , B62D5/0463 , B62D15/027
摘要： A vehicle having a driving assist system and an electric power assist steering system coupled to the driving assist system. The driving assist system transmits an assist torque request for reception by the electric power assist steering system for enabling the electric power assist steering system to adjust its outputted assist torque to accommodate requirements of the driving assist system. The assist torque request specifies a requested additional assist torque required by the driving assist system from the electric power assist steering system. In response to receiving the assist torque request, the electric power assist steering system performs an operation for determining a column torque offset as a function of both a force being applied by a driver of the vehicle on a steering column of the vehicle and the requested additional assist torque required by the driving assist system.
摘要翻译：具有驾驶辅助系统的车辆和耦合到驾驶辅助系统的电动助力转向系统。驾驶辅助系统通过电动助力转向系统发送用于接收的辅助转矩请求，以使得电动助力转向系统能够调整其输出的辅助转矩以适应驾驶辅助系统的要求。辅助转矩请求指定驾驶辅助系统从电动助力转向系统所要求的附加辅助转矩。响应于接收到辅助转矩请求，电动助力转向系统执行用于确定作为车辆驾驶员在车辆的转向柱上施加的力与所请求的附加值的函数的列扭矩偏移的操作驾驶辅助系统所需的辅助扭矩。

10. 发明授权

US09247766B2 Angiogenin-enriched milk fractions 有权
$Angiogenin-enriched milk fractions$
标题翻译：富含血管生成素的牛奶级分
公开(公告)号：US09247766B2
公开(公告)日：2016-02-02
申请号：US12992530
申请日：2009-05-14
申请人： Matthew McDonagh , Benjamin Cocks , Angus Tester , Peter Hobman , Andrew Brown
发明人： Matthew McDonagh , Benjamin Cocks , Angus Tester , Peter Hobman , Andrew Brown
IPC分类号： A61K38/46 , C12N9/22 , A23L1/305 , A23J1/20 , C07K14/515 , A61K38/00
CPC分类号： A23L1/3053 , A23J1/20 , A23L33/18 , A23L33/19 , A61K38/00 , C07K14/515
摘要： The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.
摘要翻译：本发明提供了用于富集血管生成素的乳提取物的方法，所述方法涉及通过大小，电荷或免疫亲和力分离。本发明还提供了通过该方法产生的血管生成素富集的提取物，并将其提供于药物和营养组合物以及用于治疗可被血管生成素治疗的多种疾病或病症的食物。

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