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1. 发明申请

US20130109762A1 SILK PARTICLES FOR CONTROLLED AND SUSTAINED DELIVERY OF COMPOUNDS 有权
标题翻译：用于控制和持续输送化合物的丝状颗粒
公开(公告)号：US20130109762A1
公开(公告)日：2013-05-02
申请号：US13512789
申请日：2010-11-30
申请人： Andreas Lammel , Thomas Scheibel , Martin Schwab , Gerhard Winter , Markus Hofer , Julia Myschik
发明人： Andreas Lammel , Thomas Scheibel , Martin Schwab , Gerhard Winter , Markus Hofer , Julia Myschik
IPC分类号： A61K9/00
CPC分类号： A61K9/0002 , A61K31/137 , A61K31/138 , A61K31/245 , A61K31/285 , A61K31/40 , A61K31/485 , A61K38/00 , C07K14/43518
摘要： The present invention relates to a method of producing and loading silk particles, preferably spider silk particles, with a compound. In particular, the present invention provides a novel two step method for loading silk particles, preferably spider silk particles, with small and water-soluble compounds. Also disclosed are silk particles, preferably spider silk particles, loaded with at least one compound which are eminently suited as carriers for controlled and sustained delivery applications. Furthermore, the invention relates to pharmaceutical or cosmetic compositions comprising said silk particles, preferably spider silk particles, and a pharmaceutically active compound or cosmetic compound for controlled and sustained release. The present invention is also directed to silk particles, preferably spider silk particles, loaded with a compound obtainable by the method according to the invention.
摘要翻译：本发明涉及一种用化合物生产和加载丝粒子，优选蜘蛛丝粒子的方法。特别地，本发明提供了一种用于将丝状颗粒，优选蜘蛛丝颗粒加载到小的和水溶性化合物的新颖的两步法。还公开了装载有至少一种非常适合用作控制和持续递送应用的载体的化合物的丝粒子，优选蜘蛛丝粒子。此外，本发明涉及包含所述丝粒，优选蜘蛛丝颗粒的药物或化妆品组合物，以及用于受控和持续释放的药学活性化合物或化妆品化合物。本发明还涉及装有可通过本发明方法获得的化合物的丝粒子，优选蜘蛛丝粒子。

2. 发明授权

US09233067B2 Silk particles for controlled and sustained delivery of compounds 有权
标题翻译：用于控制和持续输送化合物的丝粒
公开(公告)号：US09233067B2
公开(公告)日：2016-01-12
申请号：US13512789
申请日：2010-11-30
申请人： Andreas Lammel , Thomas Scheibel , Martin Schwab , Gerhard Winter , Markus Hofer , Julia Myschik
发明人： Andreas Lammel , Thomas Scheibel , Martin Schwab , Gerhard Winter , Markus Hofer , Julia Myschik
IPC分类号： A61K9/00 , A61K31/137 , A61K31/138 , A61K31/245 , A61K31/285 , A61K31/40 , A61K31/485 , C07K14/435 , A61K38/00
CPC分类号： A61K9/0002 , A61K31/137 , A61K31/138 , A61K31/245 , A61K31/285 , A61K31/40 , A61K31/485 , A61K38/00 , C07K14/43518
摘要： The present invention relates to a method of producing and loading silk particles, preferably spider silk particles, with a compound. In particular, the present invention provides a novel two step method for loading silk particles, preferably spider silk particles, with small and water-soluble compounds. Also disclosed are silk particles, preferably spider silk particles, loaded with at least one compound which are eminently suited as carriers for controlled and sustained delivery applications. Furthermore, the invention relates to pharmaceutical or cosmetic compositions comprising said silk particles, preferably spider silk particles, and a pharmaceutically active compound or cosmetic compound for controlled and sustained release. The present invention is also directed to silk particles, preferably spider silk particles, loaded with a compound obtainable by the method according to the invention.
摘要翻译：本发明涉及一种用化合物生产和加载丝粒子，优选蜘蛛丝粒子的方法。特别地，本发明提供了一种用于将丝状颗粒，优选蜘蛛丝颗粒加载到小的和水溶性化合物的新颖的两步法。还公开了装载有至少一种非常适合用作控制和持续递送应用的载体的化合物的丝粒子，优选蜘蛛丝粒子。此外，本发明涉及包含所述丝粒，优选蜘蛛丝颗粒的药物或化妆品组合物，以及用于受控和持续释放的药学活性化合物或化妆品化合物。本发明还涉及装有可通过本发明方法获得的化合物的丝粒子，优选蜘蛛丝粒子。

3. 发明申请

US20130099085A1 HEXAPOD 审中-公开
标题翻译：昆虫
公开(公告)号：US20130099085A1
公开(公告)日：2013-04-25
申请号：US13807575
申请日：2011-06-21
申请人： Martin Schwab
发明人： Martin Schwab
IPC分类号： F16M13/02
CPC分类号： F16M13/022 , B23Q1/5462 , B25J17/0266 , F16H21/46
摘要： The hexapod comprising a preferably plate-shaped receptacle on which at least five, preferably six rods mounted in joints are arranged wherein the other end of each rod is articulated on a mounting, wherein all the mountings can be moved along a circular railway of movement characterized by each mounting being arranged on a separate support ring wherein the respective support ring including the mounting arranged on it are movable, and by each support ring constitute the rotor or part of a rotor of an electromotive drive means comprising also a ring-shaped stator assigned to the individual support ring.
摘要翻译：六足体包括优选板状容器，其上布置有至少五个，优选六个安装在接头中的杆，其中每个杆的另一端铰接在安装件上，其中所有安装件可以沿着运动的圆形铁路运动，其特征在于通过每个安装件布置在单独的支撑环上，其中包括布置在其上的安装件的相应支撑环可移动，并且每个支撑环构成电动驱动装置的转子或转子的一部分，该电动驱动装置还包括环形定子到个人支撑环。

4. 发明授权

US08096284B2 Method for determining a rail pressure setpoint value 有权
标题翻译：确定轨道压力设定值的方法
公开(公告)号：US08096284B2
公开(公告)日：2012-01-17
申请号：US12308205
申请日：2007-07-16
申请人： Stefan Koidl , Guido Baumann , Antoine Combelle , Anthony Dieryckxvisschers , Jean-Daniel Mettetal , Pierre Mathis , Enrique Naupari , Martin Schwab , Roland Hafner
发明人： Stefan Koidl , Guido Baumann , Antoine Combelle , Anthony Dieryckxvisschers , Jean-Daniel Mettetal , Pierre Mathis , Enrique Naupari , Martin Schwab , Roland Hafner
IPC分类号： F02M59/36
CPC分类号： F02D41/3836 , F02D41/0225 , F02D41/22 , F02D2250/31
摘要： In a method for determining a rail pressure setpoint value for a high-pressure rail of an internal combustion engine, the rail pressure setpoint value is modified to a maximum degree using a maximum gradient for changing the rail pressure setpoint value, and the maximum gradient is read from a characteristics map as a function of operating parameters of the internal combustion engine. The operating parameters include an engaged gear of a gear-change transmission.
摘要翻译：在用于确定内燃机的高压轨道的轨道压力设定点值的方法中，使用用于改变轨道压力设定点值的最大坡度将轨道压力设定值修改为最大程度，并且最大梯度为根据内燃机的运行参数从特征图读出。操作参数包括齿轮变速器的啮合齿轮。

5. 发明申请

US20050260616A1 Nucleotide and protein sequences of Nogo genes and methods based thereon 失效
标题翻译： Nogo基因的核苷酸和蛋白质序列及其基础的方法
公开(公告)号：US20050260616A1
公开(公告)日：2005-11-24
申请号：US11044899
申请日：2005-01-26
申请人： Martin Schwab , Maio Chen
发明人： Martin Schwab , Maio Chen
IPC分类号： A01K67/027 , A61K31/7088 , A61K38/00 , A61K48/00 , A61P25/28 , A61P35/00 , C07K14/435 , C07K14/47 , C07K14/475 , C07K14/82 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12R1/91 , C12Q1/68 , C07H21/04 , C07K14/705 , C12P21/06
CPC分类号： C07K16/22 , A61K38/00 , C07K14/475 , C07K2317/76
摘要： The present invention relates to the gene, Nogo, its encoded protein products, as well as derivatives and analogs thereof. Production of Nogo proteins, derivatives, and antibodies is also provided. The invention further relates to therapeutic compositions and methods of diagnosis and therapy.
摘要翻译：本发明涉及基因，Nogo，其编码的蛋白质产物，以及其衍生物和类似物。还提供了Nogo蛋白质，衍生物和抗体的生产。本发明还涉及治疗组合物和诊断和治疗方法。

6. 发明申请

US20060183678A1 Nogo a binding molecules and pharmaceutical use thereof 有权
标题翻译： Nogo是一种结合分子及其药物用途
公开(公告)号：US20060183678A1
公开(公告)日：2006-08-17
申请号：US10538201
申请日：2003-12-09
申请人： Carmen Barske , Anis Mir , Thomas Oertle , Lisa Schnell , Martin Schwab , Alessandra Vitaliti , Mauro Zurini
发明人： Carmen Barske , Anis Mir , Thomas Oertle , Lisa Schnell , Martin Schwab , Alessandra Vitaliti , Mauro Zurini
IPC分类号： A61K38/17 , C07K14/47
CPC分类号： C07K14/47 , A61K2039/505 , C07K16/18 , C07K2317/55 , C07K2317/565
摘要： This invention relates to molecules, such as for example monoclonal antibodies or Fab fragments thereof, which are capable of binding to the human NogoA polypeptide or human NiG or human NiG- or human NogoA_623-640 with a dissociation constant
摘要翻译：本发明涉及能够以解离常数<1000nM与人NogoA多肽或人类NiG或人类NogoA_623-640结合的分子，例如单克隆抗体或Fab片段; 编码这种结合分子的多核苷酸; 包含这种多核苷酸的表达载体; 在治疗神经修复中使用这种结合分子，包含这种结合分子的药物组合物; 以及治疗与神经修复相关的疾病的方法。

7. 发明授权

US06327887B1 Process for shaping a work piece 有权
标题翻译：工件成形工艺
公开(公告)号：US06327887B1
公开(公告)日：2001-12-11
申请号：US09555797
申请日：2000-07-18
申请人： Otto Kunz , Martin Schwab
发明人： Otto Kunz , Martin Schwab
IPC分类号： B21D2800
CPC分类号： B21J5/12 , B21K1/30
摘要： The invention relates to process for working a workpiece (1) held between a counterholder (4) and a guide (5, 5.2) by a clamping force (14.1, 14.2) by forming a profile (3, 3.1), e.g. precision toothing, in a surface (2) of the workpiece (1) by means of a forming element (8, 8.2), the forming element (8, 8.2) being guided toward the surface (2) of the workpiece (1) at an acute angle (w) to the clamping force (14.1, 14.2) or with a rotary/thrust movement.
摘要翻译：本发明涉及通过形成轮廓（3,3.1），例如通过夹紧力（14.1,14.2）来工作在夹持器（4）和引导件（5,5.2）之间保持的工件（1）的工艺。通过成形元件（8,8.2）在工件（1）的表面（2）中精确地进行齿轮啮合，成形元件（8,8.2）被引导到工件（1）的表面（2）与夹紧力（14.1,14.2）或旋转/推力运动的锐角（w）。

8. 发明授权

US4069522A Baby commode 失效
标题翻译：婴儿车
公开(公告)号：US4069522A
公开(公告)日：1978-01-24
申请号：US680792
申请日：1976-04-27
申请人： Heinz Messmer , Martin Schwab
发明人： Heinz Messmer , Martin Schwab
IPC分类号： A47K11/04 , A47K11/06 , A47K11/02
CPC分类号： A47K11/04
摘要： A commode for a child being a body formed by a central wall defining a pot and an outer wall spaced therefrom and including a repository attached or enclosed therein for toilet accessories.
摘要翻译：一个小孩是一个由中央壁形成的身体，该中心壁形成一个锅和一个与之隔开的外壁，并包括一个附着或封闭在其中的厕所用于马桶配件。

9. 发明授权

US07356459B2 Program-controlled household appliance and method of operating the appliance 失效
标题翻译：程控家用电器及其操作方法
公开(公告)号：US07356459B2
公开(公告)日：2008-04-08
申请号：US10680382
申请日：2003-10-06
申请人： Heinz-Jürgen Bergemann , Gunnar Pautzke , Matthias Salein , Martin Schwab
发明人： Heinz-Jürgen Bergemann , Gunnar Pautzke , Matthias Salein , Martin Schwab
IPC分类号： G06F17/22
CPC分类号： D06F39/005
摘要： A household appliance with a simple to use selected operating language includes activating the programs by taking into account the special characteristics of specific languages. The household appliance includes a display unit that displays all information in a simple language. The selected language, the selected programming of the household appliance, and the selected additional functions in addition to error messages are shown on the display unit so that operational mistakes are basically prevented.
摘要翻译：具有简单使用选择的操作语言的家用电器包括通过考虑特定语言的特殊特征来激活程序。家用电器包括以简单语言显示所有信息的显示单元。显示单元上显示所选择的语言，所选择的家用电器的编程以及除了错误消息之外的所选择的附加功能，从而基本上防止了操作错误。

10. 发明授权

US07104512B2 Articulated arm especially for a device for optically capturing objects 有权
标题翻译：铰接臂特别适用于光学捕获物体的装置
公开(公告)号：US07104512B2
公开(公告)日：2006-09-12
申请号：US10498123
申请日：2003-02-19
申请人： Martin Wolf , Wilfried Pfister , Martin Schwab
发明人： Martin Wolf , Wilfried Pfister , Martin Schwab
IPC分类号： E04G3/00
CPC分类号： F16M11/38 , F16M11/10 , F16M2200/024 , H04N1/19594 , H04N2201/0436 , H04N2201/045
摘要： An articulated arm for the alignment or a capturing device for optically capturing an object to be placed on a support surface, has—as a conventional double parallelogram arm—a base part, a top part, an articulate part and two pairs of rods which connect the base part or the top part to the articulated part. The articulated arm furthermore has a shaft which is rotatably fastened to the top part and has an operative mechanical connection to one of the rods pivotably fastened to the top part. This operative connection results in a rotation of the shaft relative to the top part on pivoting of the rod.
摘要翻译：用于对准的铰接臂或用于光学地捕获待放置在支撑表面上的物体的捕获装置具有如常规的双平行四边形臂 - 基部，顶部，铰接部和两对连杆基部或顶部到铰接部。铰接臂还具有可旋转地固定到顶部的轴，并且具有与可枢转地固定到顶部的杆中的一个的可操作的机械连接。该操作连接导致杆在杆的枢转时相对于顶部的旋转。

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