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1. 发明授权

US4538605A Anesthetic apparatus 失效
标题翻译：麻醉仪器
公开(公告)号：US4538605A
公开(公告)日：1985-09-03
申请号：US473315
申请日：1983-03-08
申请人： Andras Gedeon , Leif Odselius
发明人： Andras Gedeon , Leif Odselius
IPC分类号： A61M16/00
CPC分类号： A61M16/009 , Y10S128/91
摘要： An anesthetic apparatus for administering a gaseous anesthetic comprises a breathing mask which is connected to the inspiration pipe and the expiration pipe of the apparatus and used for connecting the apparatus to the airways of a patient. To prevent harmful gaseous anesthetic from being released to the surroundings when the mask is temporarily lifted from the patient's face during anesthesia in order to check the condition of the patient, the apparatus is provided with a gas suction device which can be connected to the mask through a controllable valve. The gas suction device may be continuously operated or may be started automatically when the valve is opened. A signal emitter for generating control signals and applying these to the valve is arranged on, or in the vicinity of the mask in a manner such that it can either be activated manually by the anesthetist, or is activated automatically when the mask is lifted from the patient's face, at which time it generates a control signal for opening the valve. In this way, the suction device is connected with both the inspiration pipe of the anesthetic apparatus and with the mask, whereby all gaseous anesthetic supplied through the inspiration pipe is removed by suction, and also at least the major part of the gas exhaled by the patient is caught and removed by suction through the mask. The suction device has a capacity which at least corresponds to, and preferably exceeds, the maximum flow of gaseous anesthetic capable of being delivered by the anesthetic apparatus any one moment in time.
摘要翻译：用于施用气体麻醉剂的麻醉装置包括呼吸面罩，其连接到所述装置的吸气管和呼吸管，并用于将所述装置连接到患者的气道。为了防止在麻醉期间当面罩从患者的面部临时抬起以检查患者的状况时，有害气体麻醉剂被释放到周围环境中，该装置设置有气体吸引装置，其可以通过可控阀门。吸气装置可以连续操作，或者当阀打开时可以自动启动。用于产生控制信号并将其施加到阀的信号发射器以这样的方式布置在掩模上或其附近，使得其可以由麻醉师手动激活，或者当面罩从患者的脸部，此时它产生用于打开瓣膜的控制信号。以这种方式，抽吸装置与麻醉装置的吸气管和面罩连接，通过抽吸除去通过吸气管供给的所有气体麻醉剂，并且至少大部分由气体呼出的气体患者被吸入并通过面罩抽吸除去。抽吸装置具有至少对应于并且优选地超过能够由麻醉装置在一段时间内被输送的气体麻醉剂的最大流量的能力。

2. 发明授权

US4421113A Method and apparatus for controlling lung ventilators 失效
标题翻译：肺通气机控制方法及装置
公开(公告)号：US4421113A
公开(公告)日：1983-12-20
申请号：US269782
申请日：1981-06-02
申请人： Andras Gedeon , Ulf Lundell , Goran Pilenvik
发明人： Andras Gedeon , Ulf Lundell , Goran Pilenvik
IPC分类号： A61M16/00
CPC分类号： A61M16/00
摘要： For the purpose of carrying out an MMV-treatment (Mandatory Minute Volume) by means of a lung ventilator which includes a breathing-gas source from which a patient connected to the ventilator is able to breath spontaneously through an inspiratory line, and a ventilator unit which can be activated by means of a control signal so as to deliver to the patient through the inspiratory line a mandatory breath of determinable tidal volume from the breathing-gas source, the flow of breathing gas through the inspiratory line is continuously sensed by means of a flow meter. In a control unit there is generated a signal which is representative of the continuous integral of the difference between a reference signal and the flow signal from the flow meter. The value of the integrated difference signal is compared with a given limit value. Each time the value of the integrated difference signal reaches the limit value, the ventilator unit is activated to deliver to the patient a mandatory breath of given tidal volume. Alternatively, the ventilator unit may be arranged to deliver to the patient mandatory breaths of a constant given frequency and of a tidal volume, whose magnitude is determined with each mandatory breath, by the difference prevailing between the value of the integrated difference signal and the limit value.
摘要翻译：为了通过肺呼吸机进行MMV治疗（强制分钟体积），其包括呼吸气体来源，连接到呼吸机的患者能够通过呼吸气源自发地通过吸气管线呼吸，呼吸机单元其可以通过控制信号激活，以便通过吸气管线向患者传递来自呼吸气体源的可确定的潮气量的强制性呼吸，通过吸气管线的呼吸气体的流动通过一个流量计。在控制单元中，产生代表参考信号和来自流量计的流量信号之间的差的连续积分的信号。将积分差分信号的值与给定的极限值进行比较。每当积分差分信号的值达到极限值时，呼吸机单元被激活，以向患者输送给定潮气量的强制呼吸。或者，呼吸机单元可以被布置成将恒定给定频率的强制性呼吸和其强度由每个强制性呼吸确定的潮气量通过积分差分信号的值和极限之间的差异传递给患者值。

3. 发明授权

US4753245A Apparatus for measuring the oxygen uptake of a person 失效
标题翻译：用于测量人的氧摄取的装置
公开(公告)号：US4753245A
公开(公告)日：1988-06-28
申请号：US840916
申请日：1986-03-18
申请人： Andras Gedeon
发明人： Andras Gedeon
IPC分类号： G01F13/00 , A61B5/083 , A61M16/00 , A61M16/22 , A61B5/08
CPC分类号： A61M16/00 , A61B5/0833 , A61M16/0081 , A61M16/22 , A61M2205/3389
摘要： Apparatus for measuring the oxygen uptake of a person connected to a respirator (23) includes a closed container (1) of variable volume. The container (1) can be connected to the respiratory passages of the person, via an inspiration line (2) and an expiration line (3), so that the person can inspire from and expire to the container (1). One of the lines incorporates a carbon dioxide absorber (19) for removing carbon dioxide from the respiratory gas. Means (17,18) are provided for monitoring the volume of the container (1), and controllable means (8,9,10) are found for supplying pure oxygen gas to the container (1). The oxygen-gas supply means (8,9,10) are so controlled by the means (17,18) monitoring the volume of the bellows (1) that the volume of the bellows at a given predetermined point in the breathing cycle of the person connected to the apparatus is held substantially unchanged. Means are also provided for determining the amount of oxygen gas supplied to the container (1) herewith. The interior of the container (1) is connected to the respirator (23), via a line (11) incorporating closure means (12), so that prior to the actual measuring process the person connected to the apparatus obtains assistance in breathing from the respirator via the interior of the container (4) and the volume of gas therein assumes a state of equilibrium with respect to temperature and relative humidity prior to commencing the measuring operation. The variable container (1) is enclosed in an outer, rigid vessel (13), the interior of which communicates with the respirator (23), so as to provide requisite breathing assistance during the actual measuring process. (FIG. 1).
摘要翻译：用于测量与呼吸器（23）连接的人的氧摄取的装置包括可变体积的密闭容器（1）。容器（1）可以通过吸气管线（2）和呼吸管线（3）连接到人的呼吸通道，使得人可以启动并过期到容器（1）。其中一条线包括用于从呼吸气体中除去二氧化碳的二氧化碳吸收器（19）。提供用于监测容器（1）的体积的装置（17,18），并且发现用于向容器（1）供应纯氧气的可控制装置（8,9,10）。氧气供应装置（8,9,10）由监测波纹管（1）的体积的装置（17,18）来控制，波纹管的体积在呼吸循环中的给定预定点处的波纹管的体积与设备连接的人员基本上保持不变。还提供了用于确定供应到容器（1）的氧气的量的装置。容器（1）的内部经由包括封闭装置（12）的管线（11）连接到呼吸器（23），使得在实际测量过程之前，连接到设备的人从呼吸器通过容器（4）的内部，并且其中的气体体积在开始测量操作之前相对于温度和相对湿度呈现平衡状态。可变容器（1）被封闭在外部刚性容器（13）中，其内部与呼吸器（23）连通，以便在实际测量过程中提供必要的呼吸辅助。（图。1）。

4. 发明授权

US4200094A Apparatus for warming and moistening a respiration gas 失效
标题翻译：用于加热和润湿呼吸气体的装置
公开(公告)号：US4200094A
公开(公告)日：1980-04-29
申请号：US883125
申请日：1978-03-03
申请人： Andras Gedeon , Sven-Gunnar Olsson , Georgios Psaros
发明人： Andras Gedeon , Sven-Gunnar Olsson , Georgios Psaros
IPC分类号： A61M16/16 , A61M16/10 , A61M16/00
CPC分类号： A61M16/1045
摘要： In the illustrated embodiment, the moisture reservoir comprises a tube of gas-permeable, hygroscopic material. The exhalation flow path is into a blind axial bore of a spool like member having a series of transverse notches or cuts at the top and bottom which provide interspaces leading from the bore to the tube which covers the notches at their periphery. The notches leave integral fins or lamellae with large surface area exposed to the in-flow of dry respiration gas radially through the tube wall and into the interspaces which provide further reservoirs for moisture and warmth.
摘要翻译：在所示实施例中，湿气储存器包括透气吸湿材料管。呼出流动路径进入具有在顶部和底部具有一系列横向凹口或切口的卷轴状构件的盲轴向孔，其提供从孔到达其周边的凹口的管的空间。切口留下整体的散热片或薄片，其表面积大大地暴露于干燥呼吸气体的入口径向通过管壁并进入间隙，为进一步的水分和温度提供储存。

5. 发明授权

US5965061A Method of increasing the shelf life of a colorimetric device for indicating carbon dioxide and package containing such device 失效
标题翻译：提高用于指示二氧化碳的比色装置和含有这种装置的包装的保质期的方法
公开(公告)号：US5965061A
公开(公告)日：1999-10-12
申请号：US594059
申请日：1996-01-30
申请人： Anders Larsson , Gunilla Ostberg , Paul Krill , Andras Gedeon
发明人： Anders Larsson , Gunilla Ostberg , Paul Krill , Andras Gedeon
IPC分类号： G01N31/00 , G01N31/22 , G01J1/48
CPC分类号： G01N31/223
摘要： A method of increasing the shelf life of a reversible calorimetric device for indicating carbon dioxide is disclosed, which method comprises placing said device together with at least one non-toxic pH-lowering gas in a gas-tight wrapping or casing. A package is also disclosed which is prepared by means of said method. The invention also relates to the use of a non-toxic pH-lowering gas for increasing the shelf life of a device of the above mentioned type.
摘要翻译：公开了一种增加用于指示二氧化碳的可逆量热装置的保质期的方法，该方法包括将所述装置与至少一种无毒的降低pH的气体放置在气密包装或套管中。还公开了通过所述方法制备的包装。本发明还涉及使用无毒的降低pH的气体来提高上述类型的装置的保质期。

6. 发明授权

US4509359A Method and apparatus for measuring the concentration of a given component in a gas inhaled and/or exhaled by a patient 失效
标题翻译：用于测量由患者吸入和/或呼出的气体中的给定组分的浓度的方法和装置
公开(公告)号：US4509359A
公开(公告)日：1985-04-09
申请号：US448802
申请日：1982-12-10
申请人： Andras Gedeon , Lennart Mathiasson
发明人： Andras Gedeon , Lennart Mathiasson
IPC分类号： A61B5/08 , A61B5/083 , G01N33/00 , G01N33/497 , G01N31/00
CPC分类号： G01N33/497 , A61B5/083 , G01N33/0016
摘要： For the purpose of measuring the concentration of one or more given components of the breathing gas of a patient there is removed a small part of the breathing gas at a location immediately in front of the mouth of the patient. The withdrawn gas is passed to a measuring instrument sensitive to the component or components of interest through a line which comprises, at least in part, a thin tube of a fluorosulfonyl polymer, and the outer surface of which is in free contact with the ambient air. In this way, the temperature and relative humidity of the breathing gas supplied to the measuring instrument are brought into agreement with the temperature and relative humidity of the ambient air. By calibrating the measuring instrument with respect to the temperature and relative humidity of the surrounding air prior to carrying out the measuring operation, the measuring procedure can be carried out without disturbances caused by variations in the relative humidity and temperature of the breathing gas removed for measuring purposes.
摘要翻译：为了测量患者呼吸气体的一个或多个给定组分的浓度，在立即在患者口腔前面的位置处除去少部分呼吸气体。抽出的气体通过线至少部分地被传送到对感兴趣的组分或组分的测量仪器，该管线至少部分地包括氟磺酰聚合物的细管，并且其外表面与环境空气自由接触。这样，提供给测量仪器的呼吸气体的温度和相对湿度与环境空气的温度和相对湿度一致。通过在进行测量操作之前相对于周围空气的温度和相对湿度校准测量仪器，可以进行测量程序，而不会由于测量的呼吸气体的相对湿度和温度的变化而导致的干扰目的

7. 发明授权

US06302851B1 Method and apparatus for determining a pulmonary function parameter for gas exchange 有权
标题翻译：用于确定气体交换的肺功能参数的方法和装置
公开(公告)号：US06302851B1
公开(公告)日：2001-10-16
申请号：US09554441
申请日：2000-05-15
申请人： Andras Gedeon
发明人： Andras Gedeon
IPC分类号： A61B508
CPC分类号： A61B5/083
摘要： A method and apparatus for determining a pulmonary function parameter, EVG, indicative of a living subject's effective lung volume, namely the lung volume in which gas exchange between respiratory air and pulmonary blood takes place efficiently. The apparatus carries out the steps of the method: (1) determining for a first breath during normal steady state breathing of the subject the end-tidal carbon dioxide or oxygen concentration Pet1 and the average rate of flow Va1, over the duration T1 of the breath, of expired carbon dioxide or oxygen, (2) determining for a second breath comprising a breath-hold period the end-tidal carbon dioxide or oxygen concentration Pet2 and the average rate of flow Va2, over the duration T2 of the breath, of expired carbon dioxide or oxygen, and (3) determining EVG as a quantity proportional to the ratio of the difference between said average flow rates Va1 and Va2 to the difference between said end-tidal concentrations Pet2 and Pet1.
摘要翻译：用于确定指示活体受试者有效肺容积的肺功能参数EVG的方法和装置，即呼吸空气和肺血液之间的气体交换有效发生的肺容积。该装置执行该方法的步骤：（1）在受试者的正常稳态呼吸期间确定在潮气二氧化碳或氧浓度Pet1和平均流量Va1的持续时间T1内的第一次呼吸呼气，过氧化二氧化碳或氧气，（2）在呼吸持续时间T2内确定包含呼吸保持期的终端潮气二氧化碳或氧气浓度Pet2和平均流量Va2的第二次呼吸过量的二氧化碳或氧气，以及（3）将EVG确定为与所述平均流量Va1和Va2之间的差值与所述终潮潮气浓度Pet2和Pet1之间的差成比例的量。

8. 发明授权

US5299579A Apparatus for examining a patient's pulmonary function 失效
标题翻译：用于检查患者肺功能的装置
公开(公告)号：US5299579A
公开(公告)日：1994-04-05
申请号：US859362
申请日：1992-05-26
申请人： Andras Gedeon , Claes Mebius
发明人： Andras Gedeon , Claes Mebius
IPC分类号： A61B5/083 , A61M16/00 , A61M16/22 , G06F19/00 , A61B5/08
CPC分类号： A61B5/083 , A61M16/0081 , A61M16/22 , A61M2205/3389 , G06F19/3481
摘要： Apparatus for examining pulmonary function parameters of a patient comprises a rebreathing system (1-6) adapted to be connected with the patient and including a variable-volume reservoir (1), a carbon dioxide absorber (19) in an inhalation conduit (3) and valve means (24) for selectively switching the carbon dioxide absorber (19) on and off. A carbon dioxide meter (25) is controllable to selectively measure the carbon dioxide content of respiratory gas being exhaled and of exhaled respiratory gas collected in the reservoir (1). Volume monitoring devices (17,18) monitory the volume variations of the reservoir (1). A computing unit (30) computes the pulmonary blood flow and other pulmonary function parameters using carbon dioxide concentration parameters measured by the carbon dioxide meter (25) and ventilatory rate parameters are measured by the monitoring devices (17,18).
摘要翻译： PCT No.PCT / SE90 / 00770 Sec。 371日期：1992年5月26日 102（e）日期1992年5月26日PCT提交1990年11月23日PCT公布。第WO91 / 07912号公报日期：1991年6月13日。用于检查患者的肺功能参数的装置包括适于与患者连接并包括可变体积储存器（1），二氧化碳吸收器（19）的再呼吸系统（1-6）在吸入管道（3）和用于选择性地切换二氧化碳吸收器（19）的阀门装置（24）上。二氧化碳计（25）可控制，以选择性地测量呼出的呼吸气体的二氧化碳含量和收集在储存器（1）中的呼出气体。体积监测装置（17,18）监测储层（1）的体积变化。计算单元（30）使用由二氧化碳计（25）测量的二氧化碳浓度参数来计算肺血流量和其他肺功能参数，通气率参数由监测装置（17,18）测量。

9. 发明授权

US4788982A Device for determining depth of anaesthesia 失效
标题翻译：用于确定麻醉深度的装置
公开(公告)号：US4788982A
公开(公告)日：1988-12-06
申请号：US003035
申请日：1987-01-13
申请人： Andras Gedeon , Lars-Erik Lindblad
发明人： Andras Gedeon , Lars-Erik Lindblad
IPC分类号： A61B5/024 , A61B5/0468 , A61B5/11 , A61B5/02
CPC分类号： A61B5/4821 , A61B5/02416 , A61B5/0468 , A61B5/1106
摘要： A device for determining the depth of anaesthesia of a patient, the device including an optical measuring means (1) for measuring on a part (2) of the patient an optical parameter such as transmission or reflection, which is influenced by the circulation of the blood through this part of the patient's body, and to produce an electric signal which varies in accord with this parameter. This signal is related to the periodic variations in the blood-pressure of the patient and thus has a frequency which coincides with the heart frequency of the patient and a maximum amplitude and a minimum amplitude which are related respectively to the systolic and diastolic blood-pressure of the patient. The signal is applied to signal processing circuits (3) which determine the variation in the period of the signal (.DELTA.(R-R)) and the variation in its maximum amplitude (.DELTA.P.sub.max) or minimum amplitude (.DELTA.P.sub.min) or in the difference between its maximum and minimum amplitudes (.DELTA.(P.sub.max -P.sub.min)) and construct a magnitude (K) which is proportional to the variation in the period of the signal or is preferably proportional to the ratio between the variation in the period of the signal and the variation in the maximum amplitude or minimum amplitude of the signal or in the difference between the maximum and minimum amplitudes. This magnitude (K) is presented as a measurement of the depth to which the patient has been anesthetized.
摘要翻译：一种用于确定患者的麻醉深度的装置，所述装置包括用于在患者的一部分（2）上测量诸如透射或反射的光学参数的光学测量装置（1），所述光学参数受到血液通过患者身体的这一部分，并产生根据该参数而变化的电信号。该信号与患者的血压的周期性变化有关，因此具有与患者的心脏频率一致的频率和分别与收缩压和舒张压相关的最大振幅和最小振幅的病人。信号被施加到确定信号周期（DELTA（RR））和其最大幅度（DELTA Pmax）或最小幅度（DELTA Pmin）的变化或信号处理电路（3）中的差异的信号处理电路（3）其最大和最小幅度（DELTA（Pmax-Pmin）），并且构成与信号周期的变化成比例的幅度（K），或者优选地与信号周期的变化与信号的最大幅度或最小幅度的变化或最大和最小幅度之间的差异。这个大小（K）被表示为患者已被麻醉的深度的测量值。

10. 发明授权

US5468451A Device for indicating the presence of carbon dioxide in a patient's exhaled air 失效
标题翻译：用于指示患者呼出空气中存在二氧化碳的装置
公开(公告)号：US5468451A
公开(公告)日：1995-11-21
申请号：US190189
申请日：1994-02-10
申请人： Andras Gedeon
发明人： Andras Gedeon
IPC分类号： A61B5/08 , A61B5/083 , A61M16/04 , A61M16/08 , G01N31/22 , G01N33/00 , G01N33/497 , A61B5/097
CPC分类号： G01N33/004 , G01N31/223 , G01N33/497 , A61M2016/0413
摘要： A device for indicating the presence of CO.sub.2 in a patient's inhaled air comprises a CO.sub.2 detector including an indicator element (14) which undergoes a reversible color change in response to exposure thereof to air containing CO.sub.2 in concentrations of the same order of magnitude as the CO.sub.2 concentration of air exhaled by a human being, and also comprises a heat-moisture exchanger (12) including a housing (13) with a first connecting port (15) adapted to be connected to the trachea of a patient, and a second connecting port (15) adapted for connection to a ventilator or an anesthetic machine, for example. In a flow-through passage (P) extending between the connecting ports (15, 16) there is mounted an element (18) for the regenerative exchange of heat and moisture between, on the one hand, air flowing through the flow-through passage (P) in one direction and, on the other hand, air flowing through the flow-through passage (P) in the opposite direction. The indicator element (14) is disposed in the flow-through passage on the side of the heat-moisture exchanger element (18) remote from the first connecting port (15) and is viewable from outside the housing, and its response time for the color change is sufficiently short to enable it to change color upon each breath.
摘要翻译： PCT No.PCT / SE93 / 00554 Sec。 371日期：1994年2月10日 102（e）日期1994年2月10日PCT提交1993年6月22日PCT公布。公开号WO94 / 00756 用于指示患者吸入空气中存在CO 2的装置包括CO 2检测器，其包括指示元件（14），所述指示器元件（14）响应于其暴露于含有CO 2浓度的CO 2的空气而经历可逆的颜色变化与人类呼出的空气的二氧化碳浓度相同的数量级，并且还包括热交换器（12），其包括具有适于连接到气管的第一连接端口（15）的壳体（13）患者和适于连接到呼吸机或麻醉机的第二连接口（15）。在连接端口（15,16）之间延伸的流通通道（P）中安装有用于再次交换热量和湿气的元件（18），一方面，空气流过流通通道（P），另一方面是沿相反方向流过流通通道（P）的空气。指示器元件（14）设置在远离第一连接端口（15）的热交换器元件（18）侧的流通通道中，并且可从壳体外部看到，并且其响应时间为颜色变化足够短以使其能够在每次呼吸时改变颜色。

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