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1. 发明申请

US20120109238A1 AUTOMATIC PERSONALIZATION OF PARAMETER SETTINGS AND ALGORITHMS IN A MEDICAL DEVICE 审中-公开
标题翻译：医疗设备中参数设置和算法的自动个性化
公开(公告)号：US20120109238A1
公开(公告)日：2012-05-03
申请号：US12915863
申请日：2010-10-29
申请人： Amisha S. Patel , Luc R. Mongeon , Kenneth M. Riff
发明人： Amisha S. Patel , Luc R. Mongeon , Kenneth M. Riff
IPC分类号： A61N1/08 , A61N1/362 , A61N1/39
CPC分类号： A61N1/37252 , A61N1/37288 , G16H40/63
摘要： A system includes a data retrieval module and a determination module. The data retrieval module receives a command from a user, the command indicating a first implantable medical device (IMD) and a second IMD. The data retrieval module also retrieves a first set of data from the first IMD in response to the command and retrieves a second set of data from a datastore. The second set of data includes data retrieved from the first IMD and stored in the datastore prior to receiving the command. The determination module determines a third set of data based on the first and second sets of data and transfers the third set of data to the second IMD.
摘要翻译：系统包括数据检索模块和确定模块。数据检索模块从用户接收命令，指示第一可植入医疗装置（IMD）和第二IMD。数据检索模块还响应于命令从第一IMD检索第一组数据，并从数据存储区检索第二组数据。第二组数据包括在接收命令之前从第一IMD检索并存储在数据存储中的数据。确定模块基于第一和第二组数据确定第三组数据，并将第三组数据传送到第二IMD。

2. 发明授权

US07272433B2 Transcutaneous monitor and method of use, using therapeutic output from an implanted medical device 有权
标题翻译：经皮监护仪和使用方法，使用植入式医疗装置的治疗输出
公开(公告)号：US07272433B2
公开(公告)日：2007-09-18
申请号：US10136785
申请日：2002-04-30
申请人： Kenneth M. Riff , Gregory J. Linden , James E. Willenbring
发明人： Kenneth M. Riff , Gregory J. Linden , James E. Willenbring
IPC分类号： A61B5/02 , A61N1/18
CPC分类号： A61N1/37235 , A61B5/0031 , A61B2560/0271 , A61M5/14216 , A61M5/14244 , A61M5/14248 , A61M5/1723 , A61M37/0092 , A61M2005/14208 , A61M2005/14268 , A61M2205/3523 , A61N1/08 , A61N1/30 , A61N1/3702 , A61N1/37217 , A61N1/37258 , A61N1/37288 , G06F19/00 , G06F19/3456 , G06F19/3481 , G16H40/63
摘要： An external physiologic or implanted device monitor/controller (“monitor”) designed to be attached to the body, as for example, to the skin of the patient. The monitor is designed to detect the therapeutic outputs actually produced by the implanted medical device. Having knowledge of the operation of the implanted medical device, the monitor may then deduce, or decode, the physiologic conditions and/or devices conditions sensed by the implanted medical device. The monitor is then able to perform an action appropriate to the sensed condition and the specific implementation.
摘要翻译：外部生理或植入的设备监视器/控制器（“监视器”）被设计成附接到身体，例如，附接到患者的皮肤。该监视器设计用于检测由植入式医疗设备实际产生的治疗输出。了解植入式医疗装置的操作后，监视器可以推断或解码由植入的医疗装置感测到的生理条件和/或装置状况。监视器然后能够执行适合于感测状况和具体实现的动作。

3. 发明授权

US06529771B1 Implantable medical device for tracking patient cardiac status 失效
标题翻译：用于跟踪患者心脏状态的植入式医疗装置
公开(公告)号：US06529771B1
公开(公告)日：2003-03-04
申请号：US09723004
申请日：2000-11-27
申请人： Robert S. Kieval , Kenneth M. Riff
发明人： Robert S. Kieval , Kenneth M. Riff
IPC分类号： A61B50402
CPC分类号： A61B5/024 , A61B5/222 , A61N1/3627 , A61N1/36514 , A61N1/3702 , G06F19/00
摘要： An implantable medical device determines activity levels and Heart Rate and from a combination of these produces a value for a heart rate activity coefficient (HRAC). This value has significant diagnostic and patient tracking value. Methods and apparatus for determining this HRAC value are described. This enables physician review of patient cardiac status. Additional physiologic data can be recorded along with the HRAC data if desired, and this too, as well as the HRAC data alone, may be reported out from the implanted device to a medical communications system for alarm purposes, titrating drugs/therapies or other monitoring tasks. Further, substitutes for heart rate measurements and activity measurements are described which can be used to augment or substitute for heart rate measurements and activity measurements. These substitutes should represent cardiovascular or cardiac responsiveness to substitute for heart rate in the HRAC signal; and should represent cardiac demand to substitute for activity in the HRAC signal.
摘要翻译：可植入医疗设备确定活动水平和心率，并且从这些组合产生心率活动系数（HRAC）的值。该值具有重要的诊断和患者跟踪价值。描述用于确定该HRAC值的方法和装置。这使得医师可以检查患者的心脏状态。如果需要，还可以连同HRAC数据一起记录额外的生理数据，并且这也可以将HRAC数据单独从植入装置报告给用于报警的医疗通信系统，滴定药物/治疗或其他监测任务。此外，描述了可用于增加或代替心率测量和活动测量的心率测量和活动测量的替代。这些替代物应代表心血管或心脏反应性来代替HRAC信号中的心率; 并应代表心脏需求来替代HRAC信号中的活动。

4. 发明授权

US5351696A Method and apparatus for intracardiac electrogram morphologic analysis 失效
标题翻译：心脏电图形态学分析方法与装置
公开(公告)号：US5351696A
公开(公告)日：1994-10-04
申请号：US52359
申请日：1993-04-23
申请人： Kenneth M. Riff , Ray S. McDonald , Michael J. German
发明人： Kenneth M. Riff , Ray S. McDonald , Michael J. German
IPC分类号： A61N1/37 , A61N1/39 , A61B5/0452
CPC分类号： A61N1/371 , A61N1/3962
摘要： A method and apparatus for morphologic analysis of an electrical signal, implementable in an implantable device such as a pacemaker, cardioverter, defibrillator or the like. The morphologic analysis uses a phase plane representation of the signal, where the signal and its first derivative are plotted along orthogonal axes. A magnitude signal corresponding to the magnitude component of the trajectory of the phase plane representation is generated and applied to a comparator. The comparator produces an activation signal when the magnitude signal exceeds a predetermined threshold. In response to the activation signal, a quadrant detector selectively applies the magnitude signal to one of four integrators, the selection of one integrator over the others being based at all times upon which quadrant of the phase plane the trajectory is in. When the magnitude decreases below a predetermined threshold, the activation signal is deasserted, whereupon the respective outputs from the four integrators may be interpreted as reflecting of the trajectory of the phase plane representation of the signal. In operation, a particular cardiac event to be detected is induced in a patient, and the resultant phase plane signals are examined to determine particular aspects of the phase plane signals which can be used as an indication that the particular event has occurred. The apparatus is then conditioned to recognize such aspects in subsequent phase plane signals, in order to provide an indication when such aspects are again present in the signals.
摘要翻译：一种用于电信号形态学分析的方法和装置，可实现在诸如起搏器，心律转复器，除颤器等的可植入装置中。形态分析使用信号的相平面表示，其中信号及其一阶导数沿正交轴绘制。产生对应于相平面表示的轨迹的幅度分量的幅度信号并将其应用于比较器。当幅度信号超过预定阈值时，比较器产生激活信号。为了响应于激活信号，象限检测器选择性地将幅度信号施加到四个积分器中的一个，一个积分器的选择在所有时间上基于轨迹所在的相平面的哪个象限。当幅度减小时低于预定阈值时，激活信号被解除无效，因此来自四个积分器的相应输出可以被解释为反映信号的相位平面表示的轨迹。在操作中，在患者中诱发要检测的特定心脏事件，并检查所得的相平面信号以确定可用作特定事件已发生的指示的相平面信号的特定方面。然后将装置调节为在随后的相平面信号中识别这些方面，以便当这些方面再次存在于信号中时提供指示。

5. 发明授权

US08961505B2 Electrosurgery detection 有权
标题翻译：电外科检测
公开(公告)号：US08961505B2
公开(公告)日：2015-02-24
申请号：US13337877
申请日：2011-12-27
申请人： Kenneth M. Riff
发明人： Kenneth M. Riff
IPC分类号： A61B18/04
CPC分类号： A61N1/3925 , A61B5/0402 , A61B5/686 , A61B5/7217 , A61B5/725 , A61B18/16 , A61B2018/00595 , A61B2018/00601 , A61N1/3605 , A61N1/362 , A61N1/3718
摘要： A device includes a plurality of electrodes and a detection module. The plurality of electrodes are configured to acquire an electrical signal in a patient. The detection module is configured to determine whether the acquired electrical signal includes signal content in each of N different frequency bands and detect operation of an electrosurgical device on the patient based on how many of the N different frequency bands include signal content. N is an integer that is greater than 1.
摘要翻译：一种装置包括多个电极和检测模块。多个电极被配置为获取患者中的电信号。所述检测模块被配置为基于所述N个不同频带中的多个所述信号内容来确定所获取的电信号是否包括在N个不同频带中的每一个中的信号内容，并且检测所述患者的电外科设备的操作。 N是大于1的整数。

6. 发明授权

US5312453A Rate responsive cardiac pacemaker and method for work-modulating pacing rate deceleration 失效
标题翻译：速率响应心脏起搏器和工作调节起搏速度减速的方法
公开(公告)号：US5312453A
公开(公告)日：1994-05-17
申请号：US880877
申请日：1992-05-11
申请人： Michael B. Shelton , William J. Combs , Tommy D. Bennett , Michael R. Tollinger , Kenneth M. Riff
发明人： Michael B. Shelton , William J. Combs , Tommy D. Bennett , Michael R. Tollinger , Kenneth M. Riff
IPC分类号： A61N1/365 , A61N1/372 , A61N1/00
CPC分类号： A61N1/36514
摘要： A rate-responsive cardiac pacemaker in which deceleration of the pacing rate is modulated according to recent patient activity or "work". Based on signals provided from an activity sensor in the pacemaker, the pacemaker maintains and periodically recomputes a work value corresponding to the amount of patient activity detected over time. In response to a decrease in or cessation of detected patient activity, the pacemaker reduces the pacing rate, first at a more rapid deceleration rate, then at a lower deceleration rate, and then once again at a more rapid deceleration rate. The length of time during which the pacing rate is reduced at the lower deceleration rate is modulated according to the work value maintained by the pacemaker. The work-modulated pacing rate deceleration occurs only if certain achievement criteria are met, the achievement criteria being specified in terms of the amount of time the pacemaker's target pacing rate exceeds a predetermines rest value, and the difference between the target rate and the rest rate.
摘要翻译：根据最近的患者活动或“工作”调节起搏速度的减速的速率响应心脏起搏器。基于由起搏器中的活动传感器提供的信号，起搏器维持并周期性地重新计算与随时间检测的患者活动量相对应的工作值。响应于检测到的患者活动的减少或停止，起搏器降低起搏速率，首先以更快的减速率，然后以较低的减速率，然后再次以更快的减速率。以较低的减速率降低起搏速度的时间长短根据起搏器保持的工作值进行调制。工作调节的起搏速度减速仅在满足某些成就标准的情况下发生，成就标准是根据起搏器的目标起搏速度超过预定值的时间量指定的，目标速率与休息率之间的差异。

7. 发明授权

US07366570B2 Method and a system for using implanted medical device data for accessing therapies 有权
标题翻译：用于使用植入的医疗装置数据进行治疗的方法和系统
公开(公告)号：US07366570B2
公开(公告)日：2008-04-29
申请号：US10376061
申请日：2003-02-26
申请人： Kenneth M. Riff , Patrick M. Mahoney , Clifton W. Owens , Rahul Mehra , Michael F. Hess , Nirav V. Sheth , Nancy Perry Pool , Michael R. Ujhelyi
发明人： Kenneth M. Riff , Patrick M. Mahoney , Clifton W. Owens , Rahul Mehra , Michael F. Hess , Nirav V. Sheth , Nancy Perry Pool , Michael R. Ujhelyi
IPC分类号： A61N1/08
CPC分类号： A61N1/37258 , A61B5/0031 , A61N1/37252 , G06F19/00 , G06F19/3418 , G06F19/3456 , G16H10/60 , G16H15/00 , G16H40/63
摘要： A method and system facilitates the access by a patient of implanted medical device related data for patient participation in their own clinical care and therapy. In an example embodiment, the method includes establishing a communications link between an implanted medical device and a data processor via an implanted medical device interface. Access to a secured database is obtained via the implanted device data processor using a set of patient identification data. A query is then submitted via the data processor to the secured database in response to input patient diagnostic data. Data received from the secured database is then displayed for use in a patient evaluation.
摘要翻译：一种方法和系统便于患者接触植入的医疗装置相关数据，以使患者参与其自身临床护理和治疗。在示例实施例中，该方法包括经由植入的医疗设备接口在植入的医疗设备和数据处理器之间建立通信链路。通过使用一组患者识别数据的植入装置数据处理器获得对安全数据库的访问。然后，响应于输入的患者诊断数据，通过数据处理器将查询提交到安全数据库。然后显示从安全数据库接收到的数据以用于患者评估。

8. 发明申请

US20130165918A1 ELECTROSURGERY DETECTION 有权
标题翻译：静电检测
公开(公告)号：US20130165918A1
公开(公告)日：2013-06-27
申请号：US13337877
申请日：2011-12-27
申请人： Kenneth M. Riff
发明人： Kenneth M. Riff
IPC分类号： A61B18/16
CPC分类号： A61N1/3925 , A61B5/0402 , A61B5/686 , A61B5/7217 , A61B5/725 , A61B18/16 , A61B2018/00595 , A61B2018/00601 , A61N1/3605 , A61N1/362 , A61N1/3718
摘要： A device includes a plurality of electrodes and a detection module. The plurality of electrodes are configured to acquire an electrical signal in a patient. The detection module is configured to determine whether the acquired electrical signal includes signal content in each of N different frequency bands and detect operation of an electrosurgical device on the patient based on how many of the N different frequency bands include signal content. N is an integer that is greater than 1.
摘要翻译：一种装置包括多个电极和检测模块。多个电极被配置为获取患者中的电信号。所述检测模块被配置为基于所述N个不同频带中的多个所述信号内容来确定所获取的电信号是否包括在N个不同频带中的每一个中的信号内容，并且检测所述患者的电外科设备的操作。 N是大于1的整数。

9. 发明授权

US06190324B1 Implantable medical device for tracking patient cardiac status 有权
标题翻译：用于跟踪患者心脏状态的植入式医疗装置
公开(公告)号：US06190324B1
公开(公告)日：2001-02-20
申请号：US09301206
申请日：1999-04-28
申请人： Robert S. Kieval , Kenneth M. Riff
发明人： Robert S. Kieval , Kenneth M. Riff
IPC分类号： A61B504
CPC分类号： A61B5/024 , A61B5/222 , A61N1/3627 , A61N1/36514 , A61N1/3702 , G06F19/00
摘要： An implantable medical device determines activity levels and Heart Rate and from a combination of these produces a value for a heart rate activity coefficient (HRAC). This value has significant diagnostic and patient tracking value. Methods and apparatus for determining this HRAC value are described. This enables physician review of patient cardiac status. Additional physiologic data can be recorded along with the HRAC data if desired, and this too, as well as the HRAC data alone, may be reported out from the implanted device to a medical communications system for alarm purposes, titrating drugs/therapies or other monitoring tasks. Further, substitutes for heart rate measurements and activity measurements are described which can be used to augment or substitute for heart rate measurements and activity measurements. These substitutes should represent cardiovascular or cardiac responsiveness to substitute for heart rate in the HRAC signal; and should represent cardiac demand to substitute for activity in the HRAC signal.
摘要翻译：可植入医疗设备确定活动水平和心率，并且从这些组合产生心率活动系数（HRAC）的值。该值具有重要的诊断和患者跟踪价值。描述用于确定该HRAC值的方法和装置。这使得医师可以检查患者的心脏状态。如果需要，还可以连同HRAC数据一起记录额外的生理数据，并且这也可以将HRAC数据单独从植入装置报告给用于报警的医疗通信系统，滴定药物/治疗或其他监测任务。此外，描述了可用于增加或代替心率测量和活动测量的心率测量和活动测量的替代。这些替代物应代表心血管或心脏反应性来代替HRAC信号中的心率; 并应代表心脏需求来替代HRAC信号中的活动。

10. 发明授权

US5876353A Impedance monitor for discerning edema through evaluation of respiratory rate 失效
公开(公告)号：US5876353A
公开(公告)日：1999-03-02
申请号：US792204
申请日：1997-01-31
申请人： Kenneth M. Riff
发明人： Kenneth M. Riff
IPC分类号： A61B5/053 , A61B5/08 , A61N1/362 , A61N1/37 , A61N1/06
CPC分类号： A61B5/4878 , A61B5/0535 , A61B5/0537 , A61B5/0809 , A61N1/3702 , A61N1/3627
摘要： An impedance monitor for discerning edema through evaluation of respiratory rate. Preferred embodiment includes edema monitor and trigger to initiate diagnostic reporting or corrective action when activated. Recording of Long Term Average and Short Term Average values for secondary edema measure based on DC signal level are described as are methods and apparatus for removing unwanted recurring noise.

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