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1. 发明授权

US5372607A Method and apparatus for monitoring pacemaker intervals 失效
标题翻译：用于监测起搏器间隔的方法和装置
公开(公告)号：US5372607A
公开(公告)日：1994-12-13
申请号：US081721
申请日：1993-06-23
申请人： Karen A. Stone , Richard M. Powell , Michael R. Tollinger , Gary Berg
发明人： Karen A. Stone , Richard M. Powell , Michael R. Tollinger , Gary Berg
IPC分类号： A61N1/365 , A61N1/368 , A61N1/37
CPC分类号： A61N1/36514 , A61N1/368 , A61N1/37
摘要： A method and apparatus for optimizing the performance of a rate-responsive cardiac pacemaker. A pacemaker is provided which is capable of obtaining and storing information about a patient's cardiac function and about a pacemaker's operation during a brief exercise interval. The data collected includes information about the number of cardiac events during each two-second interval of the exercise, as well as the percentage of paced events during each two-second interval. Data reflecting the output of the pacemaker's activity sensor output is also collected for each two second interval of the test. In addition, AV interval data for each cardiac cycle during the test is collected, this data being distinguished according to whether it reflects atrial-pace-to-ventricular-sense or atrial-sense-to-ventricular-sense AV intervals. The disclosed pacemaker is operable in conjunction with an external programming/processing unit, which receives the stored data after the exercise test is concluded. The data is processed and presented on the programmer screen in a manner which enables the clinician to readily assimilate it and observe the effects of hypothetical changes in rate-response programming in the pacemaker. Additionally, the clinician is able to observe the programmed AV rate adaption profiles in conjunction with the patient's actual AV performance, and compare this data with an AV profile from a typical healthy heart.
摘要翻译：一种用于优化速率响应心脏起搏器的性能的方法和装置。提供了起搏器，其能够获得和存储关于患者的心脏功能的信息以及在短暂的运动间隔期间关于起搏器的操作。收集的数据包括关于运动的每两秒间隔期间的心脏事件的数量以及每两秒间隔期间的起搏事件的百分比的信息。也可以每两个测试间隔收集反映起搏器活动传感器输出信号的数据。此外，收集测试期间每个心动周期的AV间隔数据，根据它是否反映心房心室感觉或心房感觉到心室感觉AV间隔来区分该数据。所公开的起搏器可与外部编程/处理单元结合操作，外部编程/处理单元在运动测试结束之后接收存储的数据。数据在编程器屏幕上被处理和呈现，使得临床医生能够容易地吸收它并且观察起搏器中速率响应编程中假设变化的影响。此外，临床医生能够结合患者的实际AV性能观察编程的AV速率适应曲线，并将该数据与来自典型健康心脏的AV图像进行比较。

2. 发明授权

US5312453A Rate responsive cardiac pacemaker and method for work-modulating pacing rate deceleration 失效
标题翻译：速率响应心脏起搏器和工作调节起搏速度减速的方法
公开(公告)号：US5312453A
公开(公告)日：1994-05-17
申请号：US880877
申请日：1992-05-11
申请人： Michael B. Shelton , William J. Combs , Tommy D. Bennett , Michael R. Tollinger , Kenneth M. Riff
发明人： Michael B. Shelton , William J. Combs , Tommy D. Bennett , Michael R. Tollinger , Kenneth M. Riff
IPC分类号： A61N1/365 , A61N1/372 , A61N1/00
CPC分类号： A61N1/36514
摘要： A rate-responsive cardiac pacemaker in which deceleration of the pacing rate is modulated according to recent patient activity or "work". Based on signals provided from an activity sensor in the pacemaker, the pacemaker maintains and periodically recomputes a work value corresponding to the amount of patient activity detected over time. In response to a decrease in or cessation of detected patient activity, the pacemaker reduces the pacing rate, first at a more rapid deceleration rate, then at a lower deceleration rate, and then once again at a more rapid deceleration rate. The length of time during which the pacing rate is reduced at the lower deceleration rate is modulated according to the work value maintained by the pacemaker. The work-modulated pacing rate deceleration occurs only if certain achievement criteria are met, the achievement criteria being specified in terms of the amount of time the pacemaker's target pacing rate exceeds a predetermines rest value, and the difference between the target rate and the rest rate.
摘要翻译：根据最近的患者活动或“工作”调节起搏速度的减速的速率响应心脏起搏器。基于由起搏器中的活动传感器提供的信号，起搏器维持并周期性地重新计算与随时间检测的患者活动量相对应的工作值。响应于检测到的患者活动的减少或停止，起搏器降低起搏速率，首先以更快的减速率，然后以较低的减速率，然后再次以更快的减速率。以较低的减速率降低起搏速度的时间长短根据起搏器保持的工作值进行调制。工作调节的起搏速度减速仅在满足某些成就标准的情况下发生，成就标准是根据起搏器的目标起搏速度超过预定值的时间量指定的，目标速率与休息率之间的差异。

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