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1. 发明授权

US5780970A Multi-stage depressed collector for small orbit gyrotrons 失效
标题翻译：用于小型轨道回旋加速器的多级压缩式收集器
公开(公告)号：US5780970A
公开(公告)日：1998-07-14
申请号：US740108
申请日：1996-10-28
申请人： Amarjit Singh , R. Lawrence Ives , Richard V. Schumacher , Yosuke M. Mizuhara
发明人： Amarjit Singh , R. Lawrence Ives , Richard V. Schumacher , Yosuke M. Mizuhara
IPC分类号： H01J23/027 , H01J23/10
CPC分类号： H01J23/10 , H01J23/0275 , H01J2225/025
摘要： A multi-stage depressed collector for receiving energy from a small orbit gyrating electron beam employs a plurality of electrodes at different potentials for sorting the individual electrons on the basis of their total energy level. Magnetic field generating coils, for producing magnetic fields and magnetic iron for magnetic field shaping produce adiabatic and controlled non-adiabatic transitions of the incident electron beam to further facilitate the sorting.
摘要翻译：用于从小轨道旋转电子束接收能量的多级压陷集电体采用不同电位的多个电极，用于基于它们的总能量水平对各个电子进行分选。用于产生磁场的磁场产生线圈和用于磁场成形的磁铁使得入射电子束的绝热和受控的非绝热转变进一步便于分选。

2. 发明授权

US08470367B2 Oral drug delivery system 有权
标题翻译：口服药物输送系统
公开(公告)号：US08470367B2
公开(公告)日：2013-06-25
申请号：US11946575
申请日：2007-11-28
申请人： Nitin Bhalachandra Dharmadhikari , Yashoraj Rupsinh Zala , Amarjit Singh
发明人： Nitin Bhalachandra Dharmadhikari , Yashoraj Rupsinh Zala , Amarjit Singh
IPC分类号： A61K9/24
CPC分类号： A61K9/2072
摘要： An oral drug delivery system comprising a coated tablet having one or more surfaces. The coated tablet further comprises a core and a coating surrounding the core. The core comprises an active ingredient composition comprising at least one active ingredient and a pharmaceutically acceptable excipient and a composition selected from a swellable composition and a reactive composition located in an immediate vicinity of one or more preselected surfaces. The coating comprising water insoluble polymer(s) and leachable component(s) is operable to be reliably removed fully from the one or more of the preselected surfaces of the tablet upon contact with an aqueous environment, but not removed from at least one of the surfaces.
摘要翻译：一种口服药物递送系统，其包含具有一个或多个表面的包衣片剂。涂布的片剂还包括芯和围绕芯的涂层。核心包括活性成分组合物，其包含至少一种活性成分和药学上可接受的赋形剂，以及选自位于一个或多个预选表面附近的可溶胀组合物和反应性组合物的组合物。包含水不溶性聚合物和可浸出组分的涂层可操作以在与水性环境接触时可靠地从片剂的一个或多个预选表面完全去除，但不从至少一个表面。

3. 发明申请

US20130059004A1 ORAL DRUG DELIVERY SYSTEM 审中-公开
标题翻译：口服药物递送系统
公开(公告)号：US20130059004A1
公开(公告)日：2013-03-07
申请号：US13608712
申请日：2012-09-10
申请人： Nitin Bhalachandra Dharmadhikari , Yashoraj Rupsinh Zala , Amarjit Singh
发明人： Nitin Bhalachandra Dharmadhikari , Yashoraj Rupsinh Zala , Amarjit Singh
IPC分类号： A61K9/28 , A61K31/235 , A61K31/137 , A61P25/28 , A61P25/30 , A61P35/00 , A61P11/06 , A61P25/16 , A61P31/00 , A61P29/00 , A61P11/14 , A61P25/00 , A61P25/20 , A61P17/00 , A61K31/138
CPC分类号： A61K9/2072 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2086 , A61K9/209 , A61K9/2866 , A61K31/137 , A61K31/138 , A61K31/216
摘要： An oral drug delivery system comprising a coated tablet having one or more surfaces. The coated tablet further comprises a core and a coating surrounding the core. The core comprises an active ingredient composition comprising at least one active ingredient and a pharmaceutically acceptable excipient and a reactive composition located in an immediate vicinity of one or more preselected surfaces. The coating is operable to be reliably removed fully from the one or more of the preselected surfaces of the tablet upon contact with an aqueous environment, but not removed from at least one of the surfaces.
摘要翻译：一种口服药物递送系统，其包含具有一个或多个表面的包衣片剂。涂布的片剂还包括芯和围绕芯的涂层。核心包含活性成分组合物，其包含至少一种活性成分和药学上可接受的赋形剂和位于一个或多个预选表面附近的反应性组合物。涂层可操作以在与水性环境接触时从片剂的一个或多个预选表面完全可靠地移除，但不从至少一个表面移除。

4. 发明授权

US07765281B1 Large-scale targeted data distribution system 有权
标题翻译：大型目标数据分发系统
公开(公告)号：US07765281B1
公开(公告)日：2010-07-27
申请号：US10715928
申请日：2003-11-18
申请人： James J. Crow , James F. Kelton , Arabinda Bose , Jeremy D. Remington , Casey P. Schmit , Amarjit Singh
发明人： James J. Crow , James F. Kelton , Arabinda Bose , Jeremy D. Remington , Casey P. Schmit , Amarjit Singh
IPC分类号： G06F15/16 , G06F9/44
CPC分类号： G06F9/44 , G06F8/60 , G06F15/16
摘要： A method, system, computer system and computer program product to distribute data to arbitrarily large subsets of a very large client base, with each client computer system running client software referred to as an agent. The data distribution system uses minimal server resources and a large-scale network such as the Internet. The data to be distributed may include, for example, agent software configuration data; agent software programs, plug-ins, and associated data; announcements; and other data that is centrally managed by an administrator. Using this invention, millions of client computer systems, such as computer systems for subscribers to a broadband service, can be configured and managed centrally, while allowing data to be distributed to all or a subset of subscribers efficiently and using minimal bandwidth. Agents assist in determining whether particular data are to be distributed to them, enabling much larger-scale applications to be supported with limited server-side resources.
摘要翻译：将数据分发到非常大的客户端的任意大的子集的方法，系统，计算机系统和计算机程序产品，每个客户端计算机系统运行被称为代理的客户端软件。数据分发系统使用最少的服务器资源和诸如因特网之类的大规模网络。要分发的数据可以包括例如代理软件配置数据; 代理软件程序，插件和相关数据; 公告以及由管理员集中管理的其他数据。使用本发明，可以集中地配置和管理数百万个客户端计算机系统，例如用于宽带服务的用户的计算机系统，同时允许数据被有效地分发给订户的全部或一部分，并且使用最小的带宽。代理协助确定是否将特定数据分发给他们，从而能够通过有限的服务器端资源来支持更大规模的应用程序。

5. 发明申请

US20090110717A1 TRANSMUCOSAL COMPOSITION 审中-公开
标题翻译：转运组合物
公开(公告)号：US20090110717A1
公开(公告)日：2009-04-30
申请号：US12297486
申请日：2007-04-25
申请人： Amarjit Singh , Sarabjit Singh , Shivanand Puthli
发明人： Amarjit Singh , Sarabjit Singh , Shivanand Puthli
IPC分类号： A61K9/70 , A61K9/00 , A61K39/00 , A61K31/4178 , A61K31/4045 , A61K31/445 , A61K31/4375
CPC分类号： A61K9/0056 , A61K9/006 , A61K9/2072 , A61K9/2086
摘要： The invention provides a composition for delivering active agents through transmucosal administration, more particularly through the buccal mucosa. The composition is a unique transmucosal disk (10) which has two compartments (14) and (18); the compartments consist of at least one active agent and at least one mucoadhesive agent and both the compartments are adapted to be in contact with the mucosal membrane. The invention also provides for transmucosal administration of an active agent and method of treatment of diseases in a subject in need of such treatment.
摘要翻译：本发明提供了一种用于通过经粘膜给药递送活性剂的组合物，更具体地通过颊粘膜递送。该组合物是独特的经粘膜盘（10），其具有两个隔间（14）和（18）; 隔室由至少一种活性剂和至少一种粘膜粘附剂组成，并且两个隔室都适于与粘膜接触。本发明还提供活性剂的经粘膜给药和治疗需要这种治疗的受试者的疾病的方法。

6. 发明授权

US06346511B1 Pharmaceutical composition comprising cyclosporin 失效
标题翻译：包含环孢菌素的药物组合物
公开(公告)号：US06346511B1
公开(公告)日：2002-02-12
申请号：US09568007
申请日：2000-05-10
申请人： Amarjit Singh , Rajesh Jain
发明人： Amarjit Singh , Rajesh Jain
IPC分类号： A61K3800
CPC分类号： A61K9/4858 , A61K47/10 , A61K47/14 , A61K47/44
摘要： A homogenous substantially alcohol free composition of Cyclosporin which comprises a cyclosporin in a hydrophilic carrier medium comprising propylene glycol, esters of propylene glycol with C4 to C12 fatty acids and polyoxyethylene hydrogenated castor oils wherein the ingredients are present in the following range, Cyclosporin 1-25% w/w, Propylene Glycol 2.5-70% w/w, Esters of propylene glycol with C4 to C12 fatty acids 2.5-70% w/w and Polyoxyethylene hydrogenated Castor oils 2.5-70% w/w.
摘要翻译：一种均匀的基本上无醇的环孢菌素组合物，其在包含丙二醇的亲水载体介质中包含环孢菌素，丙二醇与C 4 -C 12脂肪酸的酯和聚氧乙烯氢化蓖麻油，其中所述成分以下列范围存在：环孢菌素1-25 ％w / w，丙二醇2.5-70％w / w，丙二醇酯，C4-C12脂肪酸酯，2.5-70％w / w，聚氧乙烯氢化蓖麻油为2.5-70％w / w。

7. 发明授权

US6017932A Pharmaceutical compositions containing at least one NSAID having increased bioavailability 失效
标题翻译：含有至少一种具有增加的生物利用度的NSAID的药物组合物
公开(公告)号：US6017932A
公开(公告)日：2000-01-25
申请号：US988211
申请日：1997-12-10
申请人： Amarjit Singh , Rajesh Jain
发明人： Amarjit Singh , Rajesh Jain
IPC分类号： A61K45/00 , A61K31/00 , A61K31/18 , A61K31/445 , A61P29/00 , A61P43/00 , A61K31/415
CPC分类号： A61K31/00
摘要： A novel composition for increasing the bioavailability of Non-steroidal Anti-inflammatory Drugs (NSAIDs), particularly those belonging to the category which exhibits its activity by selectively inhibiting cyclooxygenases-II (COX-II) and/or lipooxygenases, is disclosed. The composition is characterized in having clinically significant increased bioavailability when compared to the known compositions of the drugs. The pharmaceutical compositions comprise NSAIDs and Piperine, as herein disclosed. Enhanced bioavailability of NSAIDs results in the reduction of both dosages and dose-related side effects.
摘要翻译：公开了一种用于增加非甾体抗炎药（NSAID）的生物利用度的新型组合物，特别是那些属于通过选择性抑制环加氧酶-2（COX-II）和/或脂氧合酶显示其活性的类别的组合物。当与已知的药物组合物相比时，该组合物的特征在于具有临床显着增加的生物利用度。药物组合物包含NSAID和哌啶，如本文所公开的。 NSAIDs的生物利用度提高导致剂量和剂量相关副作用的降低。

8. 发明授权

US5945398A Pharmaceutical compositions containing cyclosporin 失效
标题翻译：含有环孢菌素的药物组合物
公开(公告)号：US5945398A
公开(公告)日：1999-08-31
申请号：US94267
申请日：1998-06-09
申请人： Amarjit Singh , Rajesh Jain
发明人： Amarjit Singh , Rajesh Jain
IPC分类号： A61K9/48 , A61K31/00 , A61K38/00 , A61K47/00 , A61K47/08 , A61K47/10 , A61K47/14 , A61K47/44 , A61P1/00 , A61P3/00 , A61P3/10 , A61P7/00 , A61P7/06 , A61P13/00 , A61P13/12 , A61P25/00 , A61P27/00 , A61P27/02 , A61P29/00 , A61P33/00 , A61P33/02 , A61P33/06 , A61P33/10 , A61P33/12 , A61P35/00 , A61P37/06 , A61P43/00 , A61K38/12 , C07K5/00 , C07K7/00
CPC分类号： A61K9/4858 , A61K47/10 , A61K47/14 , A61K47/44
摘要： A novel homogenous alcohol free, free flowing, clear and transparent pharmaceutical composition containing Cyclosporin is disclosed. The amount of Cyclosporin is easily measurable at a wide range of temperature of 15.degree. to 45.degree. C. The composition comprises a Cyclosporin in a hydrophillic carrier medium comprising propylene glycol, a transesterification product of a natural vegetable oil triglyceride and a polyalkylene polyol and polyethylene hydrogenated castor oils.
摘要翻译：公开了一种新颖的均匀无醇，自由流动，透明和透明的含有环孢菌素的药物组合物。环孢菌素的量可以在15°至45℃的宽范围的温度范围内容易地测量。该组合物包含在亲水载体介质中的环孢菌素，其包含丙二醇，天然植物油甘油三酯的转酯化产物和聚亚烷基多元醇和聚乙烯氢化蓖麻油。

9. 发明申请

US20100298011A1 Method and Appartus for Remote Software Installation and Execution on a Mobile Device 审中-公开
标题翻译：方法和Appartus在移动设备上安装和执行远程软件
公开(公告)号：US20100298011A1
公开(公告)日：2010-11-25
申请号：US12650064
申请日：2009-12-30
申请人： Edward S. Pelley , William W. Wallace , Chris Ferlita , Amarjit Singh , Bryan Tacker
发明人： Edward S. Pelley , William W. Wallace , Chris Ferlita , Amarjit Singh , Bryan Tacker
IPC分类号： H04W4/12
CPC分类号： H04W8/245 , H04M1/72525 , H04M1/72552 , H04M3/42178
摘要： A method and apparatus for remotely installing and executing software on a mobile device. A work item is formed that includes the software to be installed and executed, and a remote-execution command message is sent to the mobile device. The mobile device authenticates the remote-execution command message before extracting the remote-execution command and using it to request a download of the work item. The remote-execution command message is preferably an SMS message including a hook so that it is quickly recognizable as a remote-execution command message by the mobile device. When the work item arrives, it is authenticated before it is executed. When the mobile device determines that the execution is complete, it sends a notification to the remote-execution server.
摘要翻译：一种在移动设备上远程安装和执行软件的方法和装置。形成包括要安装和执行的软件的工作项目，并且将远程执行命令消息发送到移动设备。移动设备在提取远程执行命令并使用它来请求下载工作项目之前对远程执行命令消息进行认证。远程执行命令消息优选地是包括挂钩的SMS消息，使得其被移动设备快速识别为远程执行命令消息。当工作项目到达时，它在执行之前被认证。当移动设备确定执行完成时，它向远程执行服务器发送通知。

10. 发明申请

US20100166872A1 NOVEL IMPROVED COMPOSITIONS FOR CANCER THERAPY 审中-公开
标题翻译：用于癌症治疗的新改进组合物
公开(公告)号：US20100166872A1
公开(公告)日：2010-07-01
申请号：US12083594
申请日：2006-10-19
申请人： Amarjit Singh , Singh Sarabjit , Ajay K. Gupta , Mangesh M. Kulkarni
发明人： Amarjit Singh , Singh Sarabjit , Ajay K. Gupta , Mangesh M. Kulkarni
IPC分类号： A61K31/337 , A61K9/14 , A61P35/00 , A61K38/20 , A61K38/21 , A61K39/395
CPC分类号： A61K9/5138 , A61K9/5153 , A61K9/5169
摘要： The present invention relates to novel and improved compositions of anticancer drugs, preferably taxanes, such as paclitaxel and docetaxel, their derivatives or their analogues, methods of manufacturing these compositions and methods of fractionating the particles in particular size range and methods of treating cancer patients with these compositions, which provide reduced chemotherapy-induced side-effects especially reduced chemotherapy-induced-alopecia. The composition is such that there is substantially no free drug in the said composition.
摘要翻译：本发明涉及抗癌药物，优选紫杉烷类，例如紫杉醇和多西他赛，其衍生物或其类似物的新颖和改进的组合物，制备这些组合物的方法和将颗粒分级在特定尺寸范围内的方法以及治疗癌症患者的方法这些组合物提供降低的化学疗法诱导的副作用，特别是化疗诱导的脱发。所述组合物使得所述组合物中基本上不含游离药物。

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