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1. 发明授权

US06887386B2 Method for recovering ionic products 有权
标题翻译：回收离子产物的方法
公开(公告)号：US06887386B2
公开(公告)日：2005-05-03
申请号：US10778593
申请日：2004-02-17
申请人： Amarjeet Singh Bassi , Jingxu Zhu , Qingdao Lan , Argyrios Margaritis , Ying Zheng
发明人： Amarjeet Singh Bassi , Jingxu Zhu , Qingdao Lan , Argyrios Margaritis , Ying Zheng
IPC分类号： B01D15/02 , B01D15/04 , B01D15/18 , B01D24/00 , B01D24/36 , B01J47/10 , B01J49/00 , C02F1/42 , C02F3/30
CPC分类号： B01J47/10 , B01D15/02 , B01D15/1807 , B01D2215/021 , B01J49/10
摘要： A continuous Liquid-Solids Circulating Fluidized Bed (LSCFB) preferably for use as an ion exchanger consists of two fluidized bed columns, a fluidized bed adsorber (downer) operating in conventional fluidized bed mode for adsorption of ions of interest and a fluidized bed riser for desorption of ions (operating as a riser fluidized bed) to provide regenerated particles. Ion exchange particles circulate continuously between the riser and the downer i.e. the particles that have adsorbed ions in the absorber pass from the adsorber (downer) to the desorber where they are regenerated and the so regenerated particles are return to the adsorber near the top of the adsorber column. The LSCFB can be used in processes for continuous recovery of the ions of interest.
摘要翻译：优选用作离子交换剂的连续液固循环流化床（LSCFB）由两个流化床塔组成，流化床吸附器（下游）以常规流化床模式操作，用于吸附目的离子和流化床提升管离子的解吸（作为提升管流化床操作）以提供再生颗粒。离子交换颗粒在提升管和下降管之间连续循环，即吸收离子在吸收器（下游管）中的颗粒通过其再生的解吸器，并且这样再生的颗粒返回吸附器附近的吸附器吸附塔。 LSCFB可用于连续回收感兴趣离子的过程。

2. 发明授权

US06716344B1 Liquid-solids circulating fluidized bed 有权
标题翻译：液体固体循环流化床
公开(公告)号：US06716344B1
公开(公告)日：2004-04-06
申请号：US09676453
申请日：2000-10-02
申请人： Amarjeet Singh Bassi , Jingxu Zhu , Qing Dao Lan , Argyrios Margaritis , Ying Zheng
发明人： Amarjeet Singh Bassi , Jingxu Zhu , Qing Dao Lan , Argyrios Margaritis , Ying Zheng
IPC分类号： B01D1502
CPC分类号： B01J47/10 , B01D15/02 , B01D15/1807 , B01D2215/021 , B01J49/10
摘要： A continuous Liquid-Solids Circulating Fluidized Bed (LSCFB) preferably for use as an ion exchanger consists of two fluidized bed columns, a fluidized bed adsorber (downer) operating in conventional fluidized bed mode for adsorption of ions of interest and a fluidized bed riser for desorption of ions (operating as a riser fluidized bed) to provide regenerated particles. Ion exchange particles circulate continuously between the riser and the downer i.e. the particles that have adsorbed ions in the absorber pass from the adsorber (downer) to the desorber where they are regenerated and the so regenerated particles are return to the adsorber near the top of the adsorber column. The LSCFB can be used in processes for continuous recovery of the ions of interest.
摘要翻译：优选用作离子交换剂的连续液固循环流化床（LSCFB）由两个流化床塔组成，流化床吸附器（下游）以常规流化床模式操作，用于吸附目的离子和流化床提升管离子的解吸（作为提升管流化床操作）以提供再生颗粒。离子交换颗粒在提升管和下降管之间连续循环，即吸收离子在吸收器（下游管）中的颗粒通过其再生的解吸器，并且这样再生的颗粒返回吸附器附近的吸附器吸附塔。 LSCFB可用于连续回收感兴趣离子的过程。

3. 发明授权

US08915928B2 Finger guided suture fixation system 有权
标题翻译：手指引导缝线固定系统
公开(公告)号：US08915928B2
公开(公告)日：2014-12-23
申请号：US12905103
申请日：2010-10-15
申请人： Allen Gaynor , Michael K. Luk , Steven McClurg , Michael M. Witzmann , Ying Zheng
发明人： Allen Gaynor , Michael K. Luk , Steven McClurg , Michael M. Witzmann , Ying Zheng
IPC分类号： A61B17/10 , A61B17/04 , A61B17/062 , A61B17/00
CPC分类号： A61B17/0483 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B2017/00438
摘要： A suture fixation system includes a suture assembly having an anchor, an introducer, and a delivery device. The introducer is attachable to a finger of a person and includes a platform attached to an exterior of the introducer and a zip line attached to the platform. The delivery device is movable along the zip line and configured to removably retain the anchor. The introducer allows the finger to identify a target landmark within a patient and the delivery device is movable along the zip line and attachable to the platform to position the anchor for insertion to the target landmark.
摘要翻译：缝合线固定系统包括具有锚固件，导引器和输送装置的缝合线组件。引导器可附接到人的手指，并且包括附接到导引器的外部的平台和附接到平台的拉链线。输送装置可沿着拉链线移动并且构造成可移除地保持锚固件。引导器允许手指识别患者内的目标地标，并且输送装置可沿着拉链线移动并且可附接到平台以将锚定位置以插入目标地标。

4. 发明授权

US08758371B2 Method of fixing a suture to tissue 有权
标题翻译：将缝合线固定在组织上的方法
公开(公告)号：US08758371B2
公开(公告)日：2014-06-24
申请号：US12581893
申请日：2009-10-20
申请人： Allen Gaynor , Michael K. Luk , Steven McClurg , Michael M. Witzmann , Ying Zheng
发明人： Allen Gaynor , Michael K. Luk , Steven McClurg , Michael M. Witzmann , Ying Zheng
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B90/39 , A61B2017/00438 , A61B2017/00991 , A61B2017/0409 , A61B2017/0427 , A61B2017/06009 , A61B2017/06042
摘要： A method of fixing a suture to tissue of a patient includes placing an introducer onto a finger, the introducer including a zip line trailing from a proximal end of the introducer. The method additionally includes identifying a landmark with the finger, guiding a delivery device along the zip line toward the introducer, where the delivery device maintaining an anchor attached to a suture line, and ejecting the anchor from the delivery device and into the tissue of the patient.
摘要翻译：将缝合线固定到患者的组织的方法包括将导引器放置在手指上，导引器包括从导引器的近端延伸的拉链线。该方法另外包括用手指识别地标，沿着拉链线引导输送装置朝向导引器，其中输送装置保持锚固件附接到缝合线，并且将锚从输送装置喷射到组织中患者。

5. 发明申请

US20110092991A1 METHOD OF FIXING A SUTURE TO TISSUE 有权
标题翻译：固定组织的方法
公开(公告)号：US20110092991A1
公开(公告)日：2011-04-21
申请号：US12581893
申请日：2009-10-20
申请人： Allen Gaynor , Michael K. Luk , Steven McClurg , Michael M. Witzmann , Ying Zheng
发明人： Allen Gaynor , Michael K. Luk , Steven McClurg , Michael M. Witzmann , Ying Zheng
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B90/39 , A61B2017/00438 , A61B2017/00991 , A61B2017/0409 , A61B2017/0427 , A61B2017/06009 , A61B2017/06042
摘要： A method of fixing a suture to tissue of a patient includes placing an introducer onto a finger, the introducer including a zip line trailing from a proximal end of the introducer. The method additionally includes identifying a landmark with the finger, guiding a delivery device along the zip line toward the introducer, where the delivery device maintaining an anchor attached to a suture line, and ejecting the anchor from the delivery device and into the tissue of the patient.
摘要翻译：将缝合线固定到患者的组织的方法包括将导引器放置在手指上，导引器包括从导引器的近端延伸的拉链线。该方法另外包括用手指识别地标，沿着拉链线引导输送装置朝向导引器，其中输送装置保持锚固件附接到缝合线，并且将锚从输送装置喷射到组织中患者。

6. 发明申请

US20100003386A1 SYSTEM, METHOD AND COMPOSITIONS FOR DISPENSING A LIQUID BEVERAGE CONCENTRATE 失效
标题翻译：用于分配液体饮料浓缩物的系统，方法和组合物
公开(公告)号：US20100003386A1
公开(公告)日：2010-01-07
申请号：US12557089
申请日：2009-09-10
申请人： Pu-Sheng Cheng , Ying Zheng , Serena Laroia , Wenjie Hu , Rachid Rahmani , Eugene Scoville , Randall C. Chrisman , Shannon Gavie , Walter F. Landry , Brian J. McDonough , Randall L. Morrison , Anthony Klueppel , Christian Milo
发明人： Pu-Sheng Cheng , Ying Zheng , Serena Laroia , Wenjie Hu , Rachid Rahmani , Eugene Scoville , Randall C. Chrisman , Shannon Gavie , Walter F. Landry , Brian J. McDonough , Randall L. Morrison , Anthony Klueppel , Christian Milo
IPC分类号： A23L2/385 , A23L2/00 , A23L2/38 , A23F3/16 , A23F5/14 , A23L2/02 , A23C9/152 , A23F5/46 , A23G1/56 , A23L2/56 , B65B29/00
CPC分类号： A23F3/42 , A23C2270/15 , A23F3/426 , A23F5/243 , A23F5/267 , A23F5/486 , A23F5/505 , A23G3/48 , A23G9/42 , A23L2/44 , A23L2/56 , A23L3/3526 , A23L3/3535 , A23L27/00 , A23L27/10 , A23L27/115 , A23L27/20 , A23L27/21 , A23L27/28 , A23L27/70 , B67D1/0037 , B67D1/1231 , B67D1/1286 , B67D2001/0821 , G06K19/0707 , G06K19/0712 , G06K19/0723
摘要： A beverage system for providing a beverage, methods of making the beverage and the resulting beverage are disclosed herein. The system includes a beverage-forming concentrate and an aroma or aroma-providing component separated from the concentrate; wherein the concentrate and aroma are combinable upon reconstitution for providing the beverage. One method includes delivering a fresh beverage taste to an on-premise beverage at a point of dispensation, by delivering at least one aroma or aroma-providing component in an amount sufficient to enhance the organoleptic properties of a beverage separately from a beverage concentrate prior to when the beverage is dispensed, and mixing the aroma or aroma-providing compound with a liquid and the beverage concentrate or with a mixture of a beverage concentrate and a liquid when the beverage is being dispensed. The resulting beverage may be coffee, tea, carbonation, a juice, milk, or a non-dairy creamer-based component; or a combination thereof, while the aroma or aroma-providing component is coffee aroma, tea aroma, chocolate or cocoa aroma, malt, Maillard reaction flavor, or a combination thereof.
摘要翻译：本文公开了一种用于提供饮料的饮料系统，制造饮料和所得饮料的方法。该系统包括饮料形成浓缩物和与浓缩物分离的芳香或香味提供组分; 其中所述浓缩物和香料在重构时可组合以提供饮料。一种方法包括在分配点将新鲜饮料味道递送到内部饮料，通过递送至少一种芳香或香味提供组分，其量足以在饮料浓缩物之前分开地增强饮料的感官特性，当饮料被分配时，并且当所述饮料被分配时，将所述香气或香气提供的化合物与液体和饮料浓缩物混合，或者与饮料浓缩物和液体的混合物混合。所得到的饮料可以是咖啡，茶，碳酸化，果汁，牛奶或非乳制奶油基组分; 或其组合，而香气或香气提供成分是咖啡香气，茶香气，巧克力或可可香，麦芽，美拉德反应香料或其组合。

7. 发明授权

US06960362B2 Stabilized aroma-providing components and foodstuffs containing same 有权
标题翻译：稳定的香气提供成分和含有它的食品
公开(公告)号：US06960362B2
公开(公告)日：2005-11-01
申请号：US10661397
申请日：2003-09-11
申请人： Ying Zheng , Pu-Sheng Cheng , Christian Milo
发明人： Ying Zheng , Pu-Sheng Cheng , Christian Milo
IPC分类号： A23G1/30 , A23F3/42 , A23F5/00 , A23F5/24 , A23F5/26 , A23F5/46 , A23F5/48 , A23F5/50 , A23G1/00 , A23G3/00 , A23G3/48 , A23G9/32 , A23G9/42 , A23L1/22 , A23L1/221 , A23L1/226 , A23L1/227 , A23L1/234 , A23L2/00 , A23L2/44 , A23L2/56 , A23L3/3526 , A23L3/3535 , C11B9/00 , C11B9/02
CPC分类号： A23G3/48 , A23F3/42 , A23F3/426 , A23F5/243 , A23F5/267 , A23F5/486 , A23F5/505 , A23G9/42 , A23L2/44 , A23L2/56 , A23L3/3526 , A23L3/3535 , A23L27/00 , A23L27/10 , A23L27/115 , A23L27/20 , A23L27/21 , A23L27/28 , A23L27/70
摘要： Stabilized aroma-providing components such as chocolate, tea or coffee aromas that are stabilized against loss or degradation of desirable flavor or sensory characteristics of its aroma during storage. The stabilizing agent is present with the aroma-providing component in an amount effective to chemically interact with compounds in the aroma-providing component to (a) provide increased amounts of desirable compounds that impart desirable flavor or sensory characteristics to the aroma or (b) reduce the amount of undesirable compounds that suppress desirable flavor characteristics or that contribute to or generate undesirable flavor or sensory characteristics in the aroma. The stabilizing agent preferably is a nucleophile that contains sulfur or nitrogen, such as sulfur dioxide, sulfites, compounds or substances that contain or generate sulfites, thiols, amines or amino acids, cysteine, gluathione or an enzyme. The stabilized aroma-providing component retains the desirable flavor and sensory characteristics of the aroma for a time period of at least six months to one year or longer.
摘要翻译：稳定的芳香提供组分，例如巧克力，茶或咖啡香气，其在储存期间稳定以防止其香味所需风味或感官特性的损失或降解。存在与稳定剂一起提供香味提供成分的量，其有效化学作用与芳香提供组分中的化合物相互作用以（a）提供增加量的所需化合物，其赋予芳香所需的风味或感官特征，或（b）减少抑制所需风味特征或有助于或产生香味中的不良风味或感官特征的不期望的化合物的量。稳定剂优选是含有硫或氮的亲核试剂，例如含有或产生亚硫酸盐，硫醇，胺或氨基酸的二氧化硫，亚硫酸盐，化合物或物质，半胱氨酸，gluathione或酶。稳定的提供香味的组分在至少六个月至一年或更长的时间内保持香味的期望风味和感官特征。

8. 发明授权

US06319537B1 Stable coffee concentrate system 有权
标题翻译：稳定的咖啡浓缩系统
公开(公告)号：US06319537B1
公开(公告)日：2001-11-20
申请号：US09453932
申请日：2000-05-16
申请人： Pu-Sheng Cheng , Ying Zheng , Serena Laroia , Wenjie Hu , Rachid Rahmani
发明人： Pu-Sheng Cheng , Ying Zheng , Serena Laroia , Wenjie Hu , Rachid Rahmani
IPC分类号： A23F500
CPC分类号： G06K19/0707 , A23C2270/15 , A23F5/243 , A23F5/486 , G06K19/0712
摘要： A beverage system that contains a coffee base concentrate and coffee aroma for providing a coffee beverage. The coffee base concentrate has a soluble coffee solids concentration of at least 10% by weight and is free of coffee aroma. The coffee base concentrate and the coffee aroma are stored separately and are combined upon reconstitution for providing a coffee beverage. Separate store of the coffee base concentrate and the coffee aroma increases the stability of the system. The coffee base concentrate and/or aroma components may be further treated to improve stability, including for example adding alkali, and/or treating the coffee base concentrate to remove acid precursors, and/or protecting one or both components from oxygen, and/or storing one or both components at reduced temperature.
摘要翻译：一种饮料系统，其中含有咖啡浓缩物和用于提供咖啡饮料的咖啡香气。咖啡碱浓缩物具有至少10重量％的可溶咖啡固体浓度，并且不含咖啡香气。咖啡碱浓缩物和咖啡香气分开储存，并在重构时合并，以提供咖啡饮料。咖啡碱浓缩物和咖啡香气的独立存储增加了系统的稳定性。可以进一步处理咖啡碱浓缩物和/或芳香组分以改善稳定性，包括例如加入碱和/或处理咖啡碱浓缩物以除去酸前体，和/或保护一种或两种组分免受氧和/或在降低的温度下储存一种或两种组分。

9. 发明申请

US20140024738A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140024738A1
公开(公告)日：2014-01-23
申请号：US13983578
申请日：2012-02-23
申请人： Charlie Chen , Yuwen Liu , Yuan Xu , Ying Zheng , Junhao Ge , Li Yao , Arthur Back
发明人： Charlie Chen , Yuwen Liu , Yuan Xu , Ying Zheng , Junhao Ge , Li Yao , Arthur Back
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including 30-60 unit parts by weight of a hydrophilic monomer(s) having one N-vinyl group, 10 to 50 unit parts by weight of 2-hydroxyethyl methacrylate (HEMA), and a first siloxane monomer component comprising a siloxane monomer of formula (1) as described herein or a siloxane monomer of formula (2) as described herein or a siloxane monomer of formula (3) as described herein or any combination thereof, where the total amount of siloxane monomer(s) present in the polymerizable composition is from 15 to 40 unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了硅酮水凝胶隐形眼镜。透镜衍生自可聚合组合物，其包含30-60单位重量份的具有一个N-乙烯基的亲水性单体，10-50单位重量份的甲基丙烯酸2-羟乙酯（HEMA）和第一个硅氧烷单体组分，其包含本文所述的式（1）的硅氧烷单体或本文所述的式（2）的硅氧烷单体或本文所述的式（3）的硅氧烷单体或其任何组合，其中硅氧烷单体的总量存在于聚合性组合物中的重量比为15〜40单位份。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

10. 发明申请

US20120095445A1 METHODS AND COMPOSITIONS FOR INCREASING TRICHOGENIC POTENCY OF DERMAL CELLS 审中-公开
标题翻译：增加细胞的多发性磷酸化的方法和组合物
公开(公告)号：US20120095445A1
公开(公告)日：2012-04-19
申请号：US13378732
申请日：2010-06-16
申请人： Ying Zheng , Marylene Boucher , Ying Homan , Charles Hollow , Polina Mamontov , Kurt Stenn
发明人： Ying Zheng , Marylene Boucher , Ying Homan , Charles Hollow , Polina Mamontov , Kurt Stenn
IPC分类号： A61K35/12 , A61P17/14 , A61M37/00 , C12N5/071
CPC分类号： C07D409/12 , A61K31/381 , A61K31/4436
摘要： Methods and compositions for increasing trichogenicity of cells in culture are provided. One embodiment provides culturing dissociated mammalian dermal cells in vitro in the presence of an effective amount of one or more sonic hedgehog (Shh) pathway agonists to increase the trichogenicity of the dissociated mammalian dermal cells compared to untreated dissociated mammalian dermal cells. The cell culture optionally includes epidermal cells. Preferred Shh agonists include, but are not limited to CUR-0236715 and CUR-0201365 available from Curis, Inc. Trichogenicity is measured using the Aderans Hair Patch Assay™. The cultured dermal cells can be maintained in culture in the presence of the one or more Shh agonists for at least 1 to 7 or more days prior to harvest. The treated, cultured dermal cells can be used to treat hair loss in a mammalian subject, preferably a human, by implanting them in an effective amount to induce hair follicle formation.
摘要翻译：提供了用于增加培养物中细胞的致毛性的方法和组合物。一个实施方案在有效量的一种或多种声刺猬（Shh）途径激动剂的存在下提供培养解离的哺乳动物真皮细胞，以增加与未处理的解离的哺乳动物真皮细胞相比，解离的哺乳动物真皮细胞的致毛性。细胞培养物任选地包括表皮细胞。优选的Shh激动剂包括但不限于可从Curis，Inc。获得的CUR-0236715和CUR-0201365。使用Aderans Hair Patch Assay TM测量Trichoigenicity。培养的真皮细胞可以在收获前至少1至7天或更多天在一种或多种Shh激动剂存在下保持培养。经处理的培养的真皮细胞可用于通过将它们植入有效量以诱导毛囊形成来治疗哺乳动物受试者，优选人类的脱发。

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