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    • 2. 发明授权
    • Wine pump-over device
    • 葡萄酒抽水装置
    • US09550968B2
    • 2017-01-24
    • US14478269
    • 2014-09-05
    • Alexander MitchellEvan Schneider
    • Alexander MitchellEvan Schneider
    • C12G1/032B05B3/04
    • C12G1/0216B05B3/0463B05B3/0486Y10T137/85954
    • A device for distributing wine uniformly over a wine cap includes a T-joint member, an impeller and a shaft. The T-joint member has a top opening, a bottom opening, a side opening, a through-opening extending from the top opening to the bottom opening and a side-through-opening extending from the side opening to the through-opening. The impeller includes a one-piece conical shaped body that has a circular base, a cylindrical center, a conical-shaped outer surface, a central-through-opening extending through the cylindrical center, and a plurality of curved blades extending from the top of the cylindrical center along the inclined outer surface. The T-joint member is configured to allow wine to be pumped into the through-opening through the side opening and to exit through the bottom opening and then to flow onto the impeller. The impeller is configured to allow the wine to flow uniformly around and down the conical-shaped outer surface of the impeller and through the impeller.
    • 用于将葡萄酒均匀地分配在酒杯上的装置包括T形接头构件,叶轮和轴。 T形接头构件具有顶部开口,底部开口,侧面开口,从顶部开口延伸到底部开口的通孔,以及从侧面开口延伸到贯通开口的侧向开口。 叶轮包括一体式圆锥形主体,其具有圆形基部,圆柱形中心,圆锥形外表面,延伸穿过圆柱形中心的中心通孔,以及从顶部延伸的多个弯曲叶片 圆柱形中心沿着倾斜的外表面。 T形接头构件被配置为允许葡萄酒通过侧开口被泵入通孔并且通过底部开口排出,然后流到叶轮上。 叶轮构造成允许葡萄酒在叶轮的圆锥形外表面和通过叶轮的均匀地流动。
    • 8. 发明申请
    • Synthesis of peptide alpha-thioesters
    • 肽α-硫酯的合成
    • US20070129537A1
    • 2007-06-07
    • US10871346
    • 2004-06-18
    • Julio CamareroAlexander MitchellJames De Yoreo
    • Julio CamareroAlexander MitchellJames De Yoreo
    • C07K1/02
    • C07K5/101C07K1/061
    • Disclosed herein is a new method for the solid phase peptide synthesis (SPPS) of C-terminal peptide α thioesters using Fmoc/t-Bu chemistry. This method is based on the use of an aryl hydrazine linker, which is totally stable to conditions required for Fmoc-SPPS. When the peptide synthesis has been completed, activation of the linker is achieved by mild oxidation. The oxidation step converts the acyl-hydrazine group into a highly reactive acyl-diazene intermediate which reacts with an α-amino acid alkylthioester (H-AA-SR) to yield the corresponding peptide α-thioester in good yield. A variety of peptide thioesters, cyclic peptides and a fully functional Src homology 3 (SH3) protein domain have been successfully prepared.
    • 本文公开了使用Fmoc / t-Bu化学的C末端肽α硫酯的固相肽合成(SPPS)的新方法。 该方法基于使用芳基肼接头,其对于Fmoc-SPPS所需的条件是完全稳定的。 当肽合成完成时,通过温和氧化实现连接体的活化。 氧化步骤将酰基 - 肼基团转化为与α-氨基酸烷基硫代酯(H-AA-SR)反应的高反应性酰基 - 二氮烯中间体,从而以良好的产率得到相应的肽α-硫酯。 已经成功制备了各种肽硫酯,环肽和完全功能的Src同源3(SH3)蛋白结构域。
    • 9. 发明授权
    • Method of cutting patterns out of patterned fabrics with a cutting
apparatus which includes a scanning device
    • 用包括扫描装置的切割装置从图案织物上切割图案的方法
    • US5791215A
    • 1998-08-11
    • US211523
    • 1994-03-31
    • Kenneth MorrisonAlexander Mitchell
    • Kenneth MorrisonAlexander Mitchell
    • B23Q35/128B26D5/32D04C5/26D06H7/16D06H7/22B26D5/00
    • B26D5/32D04C5/26D06H7/16D06H7/22Y10S83/91Y10S83/94Y10T83/04Y10T83/0605Y10T83/538
    • Precise cutting of pattern strips and pattern pieces from lace and similar patterned fabrics requires correct mutual positioning of the fabric and fabric cutter for precise alignment with the boundary of the pattern pre-existing on the fabric. Patterned fabrics and especially loosely-woven lace are liable to randomly variable stretching and slippage which makes it impossible to cut under the direction of an externally imposed pattern program without regard to the instantaneous location of the pattern pre-existing on the fabric. The invention comprises lace-cutting apparatus and a lace-cutting method including optical scanning of the lace, recognition of the pattern boundary, and mutual alignment of the fabric with the fabric cutter to trace the intended cut line. Different techniques for mutual movement of the fabric and cutter are employed according to whether the pattern boundary is re-entrant or not. Preferred forms of fabric cutter include a hot-wire cutter and a laser beam cutter. The invention enables automatic high-speed cutting and trimming of lace and similar patterned fabrics.
    • PCT No.PCT / GB92 / 01813 Sec。 371日期1994年3月31日 102(e)1994年3月31日PCT提交1992年10月2日PCT公布。 出版物WO93 / 07327 日期1994年04月15日从花边和类似图案织物精确切割花纹条和花纹片需要织物和织物切割机的正确相互定位,以便与织物上预先存在的图案的边界精确对准。 图案织物和特别是松散编织的花边易于随机变化的拉伸和滑移,这使得不可能在外部施加的图案程序的方向下切割,而不考虑预先存在于织物上的图案的瞬时位置。 本发明包括花边切割装置和花边切割方法,其包括花边的光学扫描,图案边界的识别以及织物与织物切割器的相互对准以跟踪预期切割线。 根据图案边界是否进入,采用不同的织物和切割机相互移动的技术。 织物切割机的优选形式包括热丝切割机和激光切割机。 本发明实现了花边和类似图案织物的自动高速切割和修剪。