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1. 发明授权

US4259450A Antibiotic acanthomycin and process for preparing 失效
标题翻译：抗生素棘皮瘤及其制备方法
公开(公告)号：US4259450A
公开(公告)日：1981-03-31
申请号：US772552
申请日：1977-02-28
申请人： Alexander D. Argoudelis , Thomas F. Brodasky , Fritz Reusser
发明人： Alexander D. Argoudelis , Thomas F. Brodasky , Fritz Reusser
IPC分类号： C07G11/00 , A01N63/02 , A61K35/74 , A61P31/04 , C12P1/06 , C12N1/20 , A61K35/00
CPC分类号： A01N63/02
摘要： Antibiotic acanthomycin (U-53,827) produced by the controlled fermentation of the microorganism Streptomyces espinosus subsp. acanthus, NRRL 11081. This antibiotic and its base addition salts are active against Gram-positive bacteria. Accordingly, they can be used in various environments to eradicate or control such bacteria.
摘要翻译：通过微生物链霉菌Streptomyces espinosus subsp。的控制发酵产生的抗生素棘皮瘤霉素（U-53,827）鳄梨，NRRL 11081.该抗生素及其碱加成盐对革兰氏阳性菌具有活性。因此，它们可以用于各种环境中以消除或控制这些细菌。

2. 发明授权

US4689300A Antibiotic producing Streptomyces thiolactonus 失效
标题翻译：抗生素生产硫链霉菌Streptomyces thiolactonus
公开(公告)号：US4689300A
公开(公告)日：1987-08-25
申请号：US778828
申请日：1985-09-23
申请人： Lester A. Dolak , Alice L. Laborde , Oldrich K. Sebek , Thomas M. Castle , Thomas F. Brodasky
发明人： Lester A. Dolak , Alice L. Laborde , Oldrich K. Sebek , Thomas M. Castle , Thomas F. Brodasky
IPC分类号： C07D333/32 , C12P17/16 , C12N1/20 , C12P13/02 , C12R1/465
CPC分类号： C12R1/465 , C07D333/32 , C12P17/167 , Y10S435/886
摘要： Novel antibiotic U-68,204 is produced in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces thiolactonus, NRRL 15439. This antibiotic is active against various Gram-positive bacteria. Thus, antibiotic U-68,204 can be used in various environments to eradicate or control such bacteria.
摘要翻译：新颖的抗生素U-68,204在受控条件下使用微生物硫链霉菌Streptomyces thiolactonus，NRRL 15439的生物学纯培养物在发酵中产生。该抗生素对各种革兰氏阳性细菌具有活性。因此，抗生素U-68,204可用于各种环境中以消除或控制这些细菌。

3. 发明授权

US4565699A Composition of matter and process 失效
标题翻译：物质和过程的组成
公开(公告)号：US4565699A
公开(公告)日：1986-01-21
申请号：US515077
申请日：1983-07-18
申请人： Lester A. Dolak , Alice L. Laborde , Oldrich K. Sebek , Thomas M. Castle , Thomas F. Brodasky
发明人： Lester A. Dolak , Alice L. Laborde , Oldrich K. Sebek , Thomas M. Castle , Thomas F. Brodasky
IPC分类号： C12N1/20 , A61K35/74 , A61P31/04 , C07D333/32 , C07G11/00 , C12P1/06 , C12P17/16 , C12R1/465
CPC分类号： C12R1/465 , C07D333/32 , C12P17/167
摘要： Novel antibiotic U-68,204 is produced in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces thiolactonus, NRRL 15439. This antibiotic is active against various Gram-positive bacteria. Thus, antibiotic U-68,204 can be used in various environments to eradicate or control such bacteria.
摘要翻译：新颖的抗生素U-68,204在受控条件下使用微生物硫链霉菌Streptomyces thiolactonus，NRRL 15439的生物学纯培养物在发酵中产生。该抗生素对各种革兰氏阳性细菌具有活性。因此，抗生素U-68,204可用于各种环境中以消除或控制这些细菌。

4. 发明授权

US4595770A Antibiotic compound and process for recovery thereof from a fermentation broth 失效
标题翻译：抗生素化合物及其从发酵液中回收的方法
公开(公告)号：US4595770A
公开(公告)日：1986-06-17
申请号：US390093
申请日：1982-06-21
申请人： Thomas F. Brodasky , David W. Stroman
发明人： Thomas F. Brodasky , David W. Stroman
IPC分类号： C07D303/46 , C12P17/02 , C07D303/48
CPC分类号： C12R1/465 , C07D303/46 , C12P17/02
摘要： Novel antibiotic U-56,407 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces hagronensis strain 360, NRRL 15064. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus, Streptococcus pyogenes and Streptococcus pneumoniae. Thus, antibiotic U-56,407 can be used in various environments to eradicate or control such bacteria.
摘要翻译：新颖的抗生素U-56,407可以在控制条件下使用微生物链霉菌（Streptomyces hagronensis）菌株360，NRRL 15064的生物纯培养物在发酵过程中生产。该抗生素对各种革兰氏阳性菌如金黄色葡萄球菌，化脓性链球菌和肺炎链球菌。因此，抗生素U-56,407可用于各种环境以根除或控制这些细菌。

5. 发明授权

US4213326A Sample supply device 失效
标题翻译：样品供应装置
公开(公告)号：US4213326A
公开(公告)日：1980-07-22
申请号：US12067
申请日：1979-02-14
申请人： Thomas F. Brodasky
发明人： Thomas F. Brodasky
IPC分类号： G01N30/72 , H01J49/04 , G01N31/08
CPC分类号： H01J49/24 , H01J49/0495 , G01N30/7206
摘要： A sample introduction device for introducing a vaporized sample to the ion source of a mass spectrometer of a combined gas chromatography-mass spectrographic (GC/MS) apparatus. The sample introduction device replaces the jet separator of the GC/MS apparatus. The sample introduction device includes a sample holding tube which is releasably attachable to the isolation valve between the gas chromatography column and the mass spectrometer of the GC/MS apparatus. The sample introduction device includes means for connecting the sample holding tube to a vacuum source by means of a valve so that the sample holding tube can be evacuated prior to connecting the sample holding tube through the isolation valve to the ion source of the mass spectrometer.
摘要翻译：用于将气化样品引入组合气相色谱 - 质谱（GC / MS）装置的质谱仪的离子源的样品引入装置。样品引入装置代替GC / MS装置的喷射分离器。样品引入装置包括样品保持管，其可释放地附接到GC / MS装置的气相色谱柱和质谱仪之间的隔离阀。样品引入装置包括通过阀将样品保持管连接到真空源的装置，使得在将样品保持管通过隔离阀连接到质谱仪的离子源之前，样品保持管可以被抽真空。

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