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1. 发明申请

US20050159512A1 Drive arrangement for a strip of cuvettes in an analytical device 审中-公开
标题翻译：在分析装置中用于比色杯条的驱动装置
公开(公告)号：US20050159512A1
公开(公告)日：2005-07-21
申请号：US10503238
申请日：2003-01-28
申请人： Alain Rousseau , Khaled Abou-Saleh , Patrick Perin , Philippe Poutrel
发明人： Alain Rousseau , Khaled Abou-Saleh , Patrick Perin , Philippe Poutrel
IPC分类号： G01N1/00 , G01N35/02 , G01N35/04 , C08F8/00 , C08F283/00 , C08F283/12 , C08G59/00 , C08G65/04 , C08G77/00 , C08G77/38 , C08K5/09 , C08K5/10 , C08L63/00 , C08L83/00
CPC分类号： G01N35/04 , G01N35/026 , Y10T436/11 , Y10T436/114165 , Y10T436/114998
摘要： The invention relates to a drive arrangement for a series of cuvettes (C) forming a strip (2) fixed by means of a film (3) in an automatic analytical device (1), comprising at least one toothed belt (12), the teeth of which engage with the corresponding forms of the cuvettes. The above finds application in an automatic analytical device, particularly for the determination of the rate of change of the physical state of a medium.
摘要翻译：本发明涉及一种用于形成在自动分析装置（1）中通过胶片（3）固定的条带（2）的一系列比色杯（C）的驱动装置，包括至少一个齿形带（12），牙齿与相应形式的比色皿接合。以上发现在自动分析装置中的应用，特别是用于确定介质的物理状态的变化率。

2. 发明授权

US07507377B2 Device for automatic analysis of a liquid sample 有权
标题翻译：用于液体样品自动分析的装置
公开(公告)号：US07507377B2
公开(公告)日：2009-03-24
申请号：US10503239
申请日：2003-01-28
申请人： Alain Rousseau , Khaled Abou-Saleh , Patrick Perin , Philippe Poutrel
发明人： Alain Rousseau , Khaled Abou-Saleh , Patrick Perin , Philippe Poutrel
IPC分类号： G01N35/02 , G01N35/04
CPC分类号： G01N35/026 , G01N35/04 , Y10T436/11 , Y10T436/113332 , Y10T436/114998
摘要： This invention relates to a device usable in an automatical apparatus for the determination of the rate of change of the physical state of a medium. This device has a series of cuvettes having two opposites shoulders which extend in the plane of the opening of the cuvette and a flexible film which is fixed on the shoulders. This film is provided with a series of oblong opening respectively arranged above the cuvette openings. An optical detection station is provided which has a light source generating a light beam which illuminates the upper face of the cuvette bowls and an optoeleclectronic detector placed below the bottom of the bowls.
摘要翻译：本发明涉及可用于确定介质的物理状态变化率的自动装置中的装置。该装置具有一系列比色皿，其具有在比色皿开口平面上延伸的两个相对的肩部和固定在肩上的柔性膜。该膜具有分别布置在比色皿开口上方的一系列长圆形开口。提供了一种光学检测站，其具有产生照明比色皿碗的上表面的光束的光源和放置在碗的底部下方的光电检测器。

3. 发明申请

US20050175502A1 Device for automatic analysis of a liquid sample 有权
标题翻译：用于液体样品自动分析的装置
公开(公告)号：US20050175502A1
公开(公告)日：2005-08-11
申请号：US10503239
申请日：2003-01-28
申请人： Alain Rousseau , Khaled Abou-Saleh , Patrick Perin , Philippe Poutrel
发明人： Alain Rousseau , Khaled Abou-Saleh , Patrick Perin , Philippe Poutrel
IPC分类号： G01N33/49 , G01N1/00 , G01N35/02 , G01N35/04 , G01N35/00
CPC分类号： G01N35/026 , G01N35/04 , Y10T436/11 , Y10T436/113332 , Y10T436/114998
摘要： The invention relates to a device comprising a series of single-use cuvettes (C), each with a base, an upper face opposite said base with an opening and two opposing flanges (R 1 , R 2 ) which each extend from the cuvette essentially in the plane of the opening. Said cuvettes are arranged side by side and fixed to each other by means of a flexible film (3) fixed to said flanges (R 1 , R 2 ) and at least partially covering the openings of said cuvettes (C). Said film is provided with a series of openings (4) respectively arranged to the right of said openings on said cuvettes. The above finds application in an automatic analytical apparatus, particularly for the determination of the rate of change of the physical state of a medium.
摘要翻译：本发明涉及一种装置，其包括一系列单次使用的比色杯（C），每个比色皿具有基座，与基座相对的上表面具有开口和两个相对的凸缘（R s1>，R < > 2 ），其基本上在开口的平面中从比色杯延伸。所述比色皿被并排布置并且通过固定到所述凸缘（R s 1，R b 2>）的柔性膜（3）彼此固定并且至少部分地覆盖所述比色皿（C）的开口。所述膜设置有分别布置在所述比色杯上的所述开口右侧的一系列开口（4）。以上发现在自动分析装置中的应用，特别是用于确定介质的物理状态的变化率。

4. 发明申请

US20050079073A1 Automatic precision pipetting device 失效
标题翻译：自动精密移液装置
公开(公告)号：US20050079073A1
公开(公告)日：2005-04-14
申请号：US10505261
申请日：2003-02-13
申请人： Khaled Abou-Saleh , Alain Rousseau
发明人： Khaled Abou-Saleh , Alain Rousseau
IPC分类号： B01L3/02 , B01L99/00 , B67D7/36 , B67D7/70 , G01N1/00 , G01N1/38 , G01N35/00 , G01N35/10 , F04B23/00 , F04B39/00
CPC分类号： G01N35/1004 , B01L3/0203 , B01L3/0217 , B01L9/52 , G01N1/14 , G01N35/1097 , G01N2001/382 , G01N2035/00326 , Y10T137/87917 , Y10T137/87981
摘要： The invention relates to an automatic precision pipetting device. The inventive device comprises at least two cylinder/piston-type pumping units (1, 2), the rods of which are rotated by means of a common motor unit (MP). Moreover, the pumping chamber of each of the pumping units (1, 2) is connected to a circuit comprising, successively, a conduit that opens into a container of rinsing liquid (RL), three successive solenoid valves (EV1, EV2, EV3) and a portion of circuit which connects the second solenoid valve (EV2) with the pipetting means (AP). The larger pumping chamber is connected in the part of the circuit that provides the connection between the two solenoid valves (EV1, EV2) while the second pumping chamber is connected to the above-mentioned portion of circuit by means of a connector, said portion of circuit comprising a solenoid valve (EV3) which is disposed between said connector and the aforementioned pipetting means. The invention is suitable for reagent reconstitution, in particular, in an automatic analysis device.
摘要翻译：本发明涉及一种自动精密移液装置。本发明的装置包括至少两个气缸/活塞式泵送单元（1,2），其杆通过公共电动机单元（MP）旋转。此外，每个泵送单元（1,2）的泵送室连接到电路，该电路依次包括通向冲洗液体（RL）的容器的导管，三个连续的电磁阀（EV1，EV2，EV3）和连接第二电磁阀（EV2）与移液装置（AP）的电路的一部分。较大的泵送室连接在提供两个电磁阀（EV1，EV2）之间的连接的电路部分中，而第二泵送室通过连接器连接到上述电路部分，所述部分电路包括设置在所述连接器和所述吸移装置之间的电磁阀（EV3）。本发明适用于试剂重组，特别是在自动分析装置中。

5. 发明授权

US06665061B1 Method and device for detecting variations of optical properties in a sample in and analysis process 失效
标题翻译：用于检测样品中的光学性质变化和分析过程的方法和装置
公开(公告)号：US06665061B1
公开(公告)日：2003-12-16
申请号：US09959094
申请日：2001-10-18
申请人： Khaled Abou-Saleh , Patrick Fere , Alain Rousseau
发明人： Khaled Abou-Saleh , Patrick Fere , Alain Rousseau
IPC分类号： G01B2100
CPC分类号： G01N21/3151 , G01N21/51
摘要： The invention concerns a method which consists in performing for a time interval ranging between 1 ms and 10 ms a first turbidimetric measurement using a first light pulse originating from a first source (SL1) emitting in a first frequency range, a second measurement of intensity transmitted in response to a second light pulse originating from a second source (SL2) emitting in a second frequency range and, optionally determining the fluorescence of the sample. The invention is applicable to a biological analysis process as well as to hemostatic analyses.
摘要翻译：本发明涉及一种方法，其特征在于，使用来自在第一频率范围内发射的第一源（SL1）的第一光脉冲进行在1ms和10ms之间的时间间隔的第一比浊测量，发射的强度的第二测量响应于源自在第二频率范围内发射的第二源（SL2）的第二光脉冲，并且可选地确定样品的荧光。本发明适用于生物分析过程以及止血分析。

6. 发明授权

US07678332B2 Drive arrangements for a strip of cuvettes in analytical device 有权
标题翻译：驱动装置，用于分析装置中的比色杯条
公开(公告)号：US07678332B2
公开(公告)日：2010-03-16
申请号：US12033796
申请日：2008-02-19
申请人： Alain Rousseau , Khaled Abou-Saleh
发明人： Alain Rousseau , Khaled Abou-Saleh
IPC分类号： G01N35/02 , G01N35/04
CPC分类号： G01N35/04 , G01N35/026 , Y10T436/11 , Y10T436/114165 , Y10T436/114998
摘要： The invention relates to a drive arrangement for a series of cuvettes (C) forming a strip (2) fixed by means of a film (3) in an automatic analytical device (1), comprising at least one toothed belt (12), the teeth of which engage with the corresponding forms of the cuvettes. The above finds application in an automatic analytical device, particularly for the determination of the rate of change of the physical state of a medium.
摘要翻译：本发明涉及一种用于形成在自动分析装置（1）中通过胶片（3）固定的条带（2）的一系列比色杯（C）的驱动装置，包括至少一个齿形带（12），牙齿与相应形式的比色皿接合。以上发现在自动分析装置中的应用，特别是用于确定介质的物理状态的变化率。

7. 发明申请

US20090120769A1 DRIVE ARRANGEMENTS FOR A STRIP OF CUVETTES IN ANALYTICAL DEVICE 有权
标题翻译：分析装置中的条纹的驱动装置
公开(公告)号：US20090120769A1
公开(公告)日：2009-05-14
申请号：US12033796
申请日：2008-02-19
申请人： Alain Rousseau , Khaled Abou-Saleh
发明人： Alain Rousseau , Khaled Abou-Saleh
IPC分类号： B65G15/58
CPC分类号： G01N35/04 , G01N35/026 , Y10T436/11 , Y10T436/114165 , Y10T436/114998
摘要： The invention relates to a drive arrangement for a series of cuvettes (C) forming a strip (2) fixed by means of a film (3) in an automatic analytical device (1), comprising at least one toothed belt (12), the teeth of which engage with the corresponding forms of the cuvettes. The above finds application in an automatic analytical device, particularly for the determination of the rate of change of the physical state of a medium.
摘要翻译：本发明涉及一种用于形成在自动分析装置（1）中通过胶片（3）固定的条带（2）的一系列比色杯（C）的驱动装置，包括至少一个齿形带（12），牙齿与相应形式的比色皿接合。以上发现在自动分析装置中的应用，特别是用于确定介质的物理状态的变化率。

8. 发明授权

US07470402B2 Automatic precision pipetting device 失效
标题翻译：自动精密移液装置
公开(公告)号：US07470402B2
公开(公告)日：2008-12-30
申请号：US10505261
申请日：2003-02-13
申请人： Khaled Abou Saleh , Alain Rousseau
发明人： Khaled Abou Saleh , Alain Rousseau
IPC分类号： B01L3/02 , B67D5/34 , B67D5/52
CPC分类号： G01N35/1004 , B01L3/0203 , B01L3/0217 , B01L9/52 , G01N1/14 , G01N35/1097 , G01N2001/382 , G01N2035/00326 , Y10T137/87917 , Y10T137/87981
摘要： The invention relates to an automatic precision pipetting device. The inventive device comprises at least two cylinder/piston-type pumping units (1, 2), the rods of which are rotated by means of a common motor unit (MP). Moreover, the pumping chamber of each of the pumping units (1, 2) is connected to a circuit comprising, successively, a conduit that opens into a container of rinsing liquid (RL), three successive solenoid valves (EV1, EV2, EV3) and a portion of circuit which connects the second solenoid valve (EV2) with the pipetting means (AP). The larger pumping chamber is connected in the part of the circuit that provides the connection between the two solenoid valves (EV1, EV2) while the second pumping chamber is connected to the above-mentioned portion of circuit by means of a connector, said portion of circuit comprising a solenoid valve (EV3) which is disposed between said connector and the aforementioned pipetting means. The invention is suitable for reagent reconstitution, in particular, in an automatic analysis device.
摘要翻译：本发明涉及一种自动精密移液装置。本发明的装置包括至少两个气缸/活塞式泵送单元（1,2），其杆通过公共电动机单元（MP）旋转。此外，每个泵送单元（1,2）的泵送室连接到电路，该电路依次包括通向冲洗液体（RL）的容器的导管，三个连续的电磁阀（EV1，EV2，EV3）和连接第二电磁阀（EV2）与移液装置（AP）的电路的一部分。较大的泵送室连接在提供两个电磁阀（EV1，EV2）之间的连接的电路部分中，而第二泵送室通过连接器连接到上述电路部分，所述部分电路包括设置在所述连接器和所述吸移装置之间的电磁阀（EV3）。本发明适用于试剂重组，特别是在自动分析装置中。

9. 发明授权

US6135172A Device for sampling and/or injecting inside a plugged sample tube 有权
标题翻译：用于在插入式样品管内取样和/或注入的装置
公开(公告)号：US6135172A
公开(公告)日：2000-10-24
申请号：US284606
申请日：1999-04-19
申请人： Patrick Fere , Patrick Perin , Alain Rousseau
发明人： Patrick Fere , Patrick Perin , Alain Rousseau
IPC分类号： A61M5/162 , A61M5/32 , B01J4/00 , B01L3/00 , B65D39/04 , B67B7/86 , B67C3/00 , G01N1/00 , G01N1/10 , G01N35/02 , G01N35/10
CPC分类号： G01N35/1079 , A61M5/162 , A61M5/3286 , B01L3/00 , B67B7/24 , B67B7/28 , G01N1/00 , A61M2205/192
摘要： The invention concerns a hollow needle axially mobile so as to pierce a container stopper. Said needle comprises a pointed end with a cutting edge tangent to the needle cylindrical body generatrix, an oblique shape linking the edge to said cylindrical body and a side outlet orifice of the channel centred on said generatrix and a site spaced from the edge, said orifice being centred perpendicular to the needle longitudinal axis. This invention is applicable to automatic and semiautomatic analytical equipment.
摘要翻译： PCT No.PCT / FR98 / 01734 Sec。 371 1999年4月19日第 102（e）日期1999年4月19日PCT提交1998年7月30日PCT公布。出版物WO99 / 09389 日期1999年2月25日本发明涉及一种轴向移动以刺穿容器塞子的空心针。所述针头包括具有与针筒体母线相切的切割边缘的尖端，将边缘连接到所述圆柱体的斜形形状和以所述母线为中心的通道的侧出口孔和与边缘间隔开的位置，所述孔垂直于针纵向轴线居中。本发明适用于自动和半自动分析设备。

10. 发明授权

US07959878B2 Unit cuvette for analyzing a biological fluid, automatic device for in vitro analysis 有权
标题翻译：用于分析生物液体的单位比色皿，用于体外分析的自动装置
公开(公告)号：US07959878B2
公开(公告)日：2011-06-14
申请号：US12087492
申请日：2007-01-17
申请人： Alain Rousseau
发明人： Alain Rousseau
IPC分类号： B01L3/00
CPC分类号： B01L3/50855 , B01L2200/025 , G01N21/03 , G01N35/025 , G01N2035/041 , G01N2035/0465
摘要： The bottom of the cuvette comprises a curved raceway placed so as to guide the oscillating movement of a ball inserted into the cuvette. In addition, the cuvette comprises means of attachment, in two perpendicular directions, to adjacent unit cuvettes. The cuvettes can thus be stored as plates in a feed magazine of an analytical device. The analytical device comprises several stations placed around a rotary ring. Only where it is desired to determine the clotting time of the blood contained in the cuvette a ball is introduced into the latter, at a ball distribution post. The cuvette equipped in this way is then brought to a station where the test is carried out. The major advantage of the invention is the polyvalence of the cuvette and of the analytical device.
摘要翻译：比色皿的底部包括弯曲的滚道，以便引导插入比色杯中的球的摆动运动。此外，试管包括在两个垂直方向上连接到相邻的单位比色皿的装置。因此，反应杯可以作为板储存在分析装置的进料仓中。分析装置包括围绕旋转环放置的若干台。只有在需要确定包含在比色杯中的血液的凝血时间的情况下，在球分配柱处将球引入后者。以这种方式装备的比色杯然后被带到进行测试的工位。本发明的主要优点是比色皿和分析装置的多价性。

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