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1. 再颁专利

USRE35695E Stabilized polyphenylene ether resin and process for the preparation of the same 失效
标题翻译：稳定的聚苯醚树脂及其制备方法
公开(公告)号：USRE35695E
公开(公告)日：1997-12-16
申请号：US330063
申请日：1994-10-26
申请人： Akihiro Kanayama , Sumio Ueda, deceased , Yoshiko Ueda, heiress , Sadao Ibe
发明人： Akihiro Kanayama , Sumio Ueda, deceased , Yoshiko Ueda, heiress , Sadao Ibe
IPC分类号： C08J5/18 , C08G65/48 , C08L25/00 , C08L25/04 , C08L71/12
CPC分类号： C08G65/485 , C08L71/126 , Y10S525/905
摘要： Disclosed is a stabilized polyphenylene ether resin which comprises a plurality of polyphenylene ether chains, which chains collectively contain terminal 6-chroman groups in an amount of at least 0.01 in terms of the number of the terminal 6-chroman groups per 100 polyphenylene ether units in the resin. This polyphenylene ether resin has excellent resistance to thermal oxidation. A composition comprising this stabilized polyphenylene ether resin and a polystyrene resin has not only high resistance to thermal oxidation but also excellent moldability.
摘要翻译： PCT No.PCT / JP89 / 00538 Sec。 371日期1989年8月26日 102（e）日期1989年8月26日PCT申请日1989年5月30日公开是一种稳定的聚苯醚树脂，其包含多个聚苯醚链，该链总共含有末端6-苯并二氢吡喃基，其量为至少0.01 在树脂中每100个聚苯醚单元的末端6-苯并二氢吡喃基数目。该聚苯醚树脂具有优异的耐热氧化性。包含该稳定化聚苯醚树脂和聚苯乙烯树脂的组合物不仅具有高的热氧化性，而且成型性优异。

2. 发明授权

US06495365B1 Hematopoietic stem cell proliferating agents 失效
标题翻译：造血干细胞增殖剂
公开(公告)号：US06495365B1
公开(公告)日：2002-12-17
申请号：US09147689
申请日：1999-05-13
申请人： Yoshimasa Saito , Yoshiko Ueda , Kouichi Tamura , Yoko Takata , Hisashi Yamada , Tatsuo Yamashita , Masakazu Kobayashi
发明人： Yoshimasa Saito , Yoshiko Ueda , Kouichi Tamura , Yoko Takata , Hisashi Yamada , Tatsuo Yamashita , Masakazu Kobayashi
IPC分类号： C12N500
CPC分类号： A61K38/30 , A61K2300/00
摘要： This invention relates to a hematopoietic stem cell proliferating agent comprising IGF-I, a hematopoietic stem cell proliferating agent comprising IGF-I and at least one protein selected from among SCF, M-CSF, and G-CSF, and a method of growing hematopoietic stem cells which comprises culturing hematopoietic stem cells in a medium containing IGF-I and at least one protein selected from the group consisting of SCF and M-CSF. The hematopoietic stem cell proliferating agent of the invention causes hematopoietic stem cells to proliferate in the undifferentiated state whether in vivo or in vitro and can, therefore, be used for amelioration of the cytopenia induced by radiotherapy or chemotherapy using anticancer drugs, prevention of infectious diseases associated with lymphopenia, or in vitro culture for multiplication of hematopoietic stem cells and extrasomatic culture of recombinant stem cells in gene therapy.
摘要翻译：本发明涉及造血干细胞增殖剂，其包含IGF-I，包含IGF-I的造血干细胞增殖剂和选自SCF，M-CSF和G-CSF中的至少一种蛋白质，以及造血造血干细胞增殖的方法干细胞，其包括在含有IGF-I和至少一种选自SCF和M-CSF的蛋白质的培养基中培养造血干细胞。本发明的造血干细胞增殖剂引起造血干细胞在未分化的细胞中增殖说明是否在体内或体外，因此可以用于改善由放射治疗或化疗引起的血细胞减少症，使用抗癌药物，预防与淋巴细胞减少有关的感染性疾病，或体外培养造血干细胞和外植体培养物基因治疗中的重组干细胞。

3. 发明授权

US07037892B2 Hematopoietic stem cell proliferating agents 失效
公开(公告)号：US07037892B2
公开(公告)日：2006-05-02
申请号：US10198355
申请日：2002-07-19
申请人： Yoshimasa Saito , Yoshiko Ueda , Kouichi Tamura , Yoko Takata , Hisashi Yamada , Tatsuo Yamashita , Masakazu Kobayashi
发明人： Yoshimasa Saito , Yoshiko Ueda , Kouichi Tamura , Yoko Takata , Hisashi Yamada , Tatsuo Yamashita , Masakazu Kobayashi
IPC分类号： A61K38/30
CPC分类号： A61K38/30 , A61K2300/00
摘要： This invention relates to a hematopoietic stem cell proliferating agent comprising IGF-I, a hematopoietic stem cell proliferating agent comprising IGF-I and at least one protein selected from among SCF, M-CSF, and G-CSF, and a method of growing hematopoietic stem cells which comprises culturing hematopoietic stem cells in a medium containing IGF-I and at least one protein selected from the group consisting of SCF and M-CSF.The hematopoietic stem cell proliferating agent of the invention causes hematopoietic stem cells to proliferate in the undifferentiated state whether in vivo or in vitro and can, therefore, be used for amelioration of the cytopenia induced by radiotherapy or chemotherapy using anticancer drugs, prevention of infectious diseases associated with lymphopenia, or in vitro culture for multiplication of hematopoietic stem cells and extrasomatic culture of recombinant stem cells in gene therapy.

4. 发明授权

US5866598A Medicament for treating or preventing cerebrovascular dementia 失效
标题翻译：用于治疗或预防脑血管性痴呆的药物
公开(公告)号：US5866598A
公开(公告)日：1999-02-02
申请号：US958317
申请日：1997-10-27
申请人： Kiyotaka Katsuta , Hiroyuki Takamatsu , Yoshiko Ueda , Hajime Nakanishi , Keizo Yoshida
发明人： Kiyotaka Katsuta , Hiroyuki Takamatsu , Yoshiko Ueda , Hajime Nakanishi , Keizo Yoshida
IPC分类号： C07D487/04 , A61K31/40 , A61K31/415 , A61K31/435 , A61K31/437 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/505 , A61P9/00 , C07D401/06 , C07D403/06 , C07D471/04
CPC分类号： A61K31/437 , A61K31/415 , A61K31/44 , A61K31/445 , A61K31/505
摘要： Compounds for treating or preventing cerebrovascular diseases are disclosed. These compounds are 5-HT antagonists. More specifically, these compounds, when combined with pharmaceutically acceptable carriers or excipients and administered to animals including humans, are useful in treating or preventing cerebrovascular dementia.
摘要翻译：公开了治疗或预防脑血管疾病的化合物。这些化合物是5-HT拮抗剂。更具体地说，这些化合物当与药学上可接受的载体或赋形剂组合并施用于包括人在内的动物时可用于治疗或预防脑血管性痴呆。

5. 发明授权

US5698561A Medicament for treating or preventing cerebrovascular dementia 失效
标题翻译：用于治疗或预防脑血管性痴呆的药物
公开(公告)号：US5698561A
公开(公告)日：1997-12-16
申请号：US736248
申请日：1996-10-24
申请人： Kiyotaka Katsuta , Hiroyuki Takamatsu , Yoshiko Ueda , Hajime Nakanishi , Keizo Yoshida
发明人： Kiyotaka Katsuta , Hiroyuki Takamatsu , Yoshiko Ueda , Hajime Nakanishi , Keizo Yoshida
IPC分类号： C07D487/04 , A61K31/40 , A61K31/415 , A61K31/435 , A61K31/437 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/505 , A61P9/00 , C07D401/06 , C07D403/06 , C07D471/04
CPC分类号： A61K31/437 , A61K31/415 , A61K31/44 , A61K31/445 , A61K31/505
摘要： Compounds for treating or preventing cerebrovascular diseases are disclosed. These compounds are 5-HT antagonists. More specifically, these compounds, when combined with pharmaceutically acceptable carriers or excipients and administered to animals including humans, are useful in treating or preventing cerebrovascular dementia.
摘要翻译：公开了治疗或预防脑血管疾病的化合物。这些化合物是5-HT拮抗剂。更具体地说，这些化合物当与药学上可接受的载体或赋形剂组合并施用于包括人在内的动物时可用于治疗或预防脑血管性痴呆。

6. 发明授权

US5607938A Medicament for treating or preventing cerebrovascular infarction 失效
标题翻译：用于治疗或预防脑血管梗死的药物
公开(公告)号：US5607938A
公开(公告)日：1997-03-04
申请号：US513805
申请日：1995-09-08
申请人： Kiyotaka Katsuta , Hiroyuki Takamatsu , Yoshiko Ueda , Hajime Nakanishi , Keizo Yoshida
发明人： Kiyotaka Katsuta , Hiroyuki Takamatsu , Yoshiko Ueda , Hajime Nakanishi , Keizo Yoshida
IPC分类号： C07D487/04 , A61K31/40 , A61K31/415 , A61K31/435 , A61K31/437 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/505 , A61P9/00 , C07D401/06 , C07D403/06 , C07D471/04
CPC分类号： A61K31/437 , A61K31/415 , A61K31/44 , A61K31/445 , A61K31/505
摘要： The present invention is drawn to methods for treating cerebral infarction by administering to a patient in need thereof an effective amount of a compound of the formulae (I, II or III): ##STR1##
摘要翻译： PCT No.PCT / JP94 / 00249 Sec。 371日期1995年9月8日 102（e）日期1995年9月8日PCT 1994年2月16日PCT PCT。 WO94 / 20102 PCT出版物日本1994年9月15日本发明涉及通过向有需要的患者施用有效量的式（I，II或III）化合物来治疗脑梗死的方法：（二）（三）

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