专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20110185440A1 CISD2-Knockout Mice and Uses Thereof 审中-公开
标题翻译： CISD2-Knockout小鼠及其用途
公开(公告)号：US20110185440A1
公开(公告)日：2011-07-28
申请号：US13041821
申请日：2011-03-07
申请人： Ting-Fen Tsai , Yi-Fan Chen , Shih-Feng Tsai , Ya-Ting Chen
发明人： Ting-Fen Tsai , Yi-Fan Chen , Shih-Feng Tsai , Ya-Ting Chen
IPC分类号： A01K67/027
CPC分类号： A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/035 , C07K14/4702 , C12N15/8509 , C12N2503/02 , C12N2510/00 , C12N2517/02 , C12Q1/6883 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要： The present invention is related to a Cisd2 knockout mouse with phenotype comprising mitochondrial breakdown and dysfunction, wherein Cisd2 is defined as SEQ ID NO. 1. The present invention is also related to a mouse model of Wolfram Syndrome 2 (WFS2) disease consisting of a Cisd2 knockout mouse. The present invention is further related to a method for screening a candidate agent for preventing or treating WFS2 disease.
摘要翻译：本发明涉及具有包括线粒体分解和功能障碍的表型的Cisd2敲除小鼠，其中Cisd2定义为SEQ ID NO：本发明还涉及由Cisd2敲除小鼠组成的Wolfram综合征2（WFS2）疾病的小鼠模型。本发明还涉及用于筛选候选药物以预防或治疗WFS2疾病的方法。

2. 发明申请

US20090249501A1 CISD2-Knockout Mice and Uses Thereof 审中-公开
标题翻译： CISD2-Knockout小鼠及其用途
公开(公告)号：US20090249501A1
公开(公告)日：2009-10-01
申请号：US12481042
申请日：2009-06-09
申请人： Ting-Fen Tsai , Yi-Fan Chen , Shih-Feng Tsai , Ya-Ting Chen
发明人： Ting-Fen Tsai , Yi-Fan Chen , Shih-Feng Tsai , Ya-Ting Chen
IPC分类号： G01N33/53 , A01K67/027
CPC分类号： C07K14/47 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/035 , C12N15/8509 , C12N2503/02 , C12N2510/00 , C12N2517/02 , C12Q1/6883 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/5088 , G01N33/6896 , G01N2800/285
摘要： The present invention is related to a Cisd2 knockout mouse with phenotype comprising mitochondrial breakdown and dysfunction, wherein Cisd2 is defined as SEQ ID NO. 1. The present invention is also related to a mouse model of Wolfram Syndrome 2 (WFS2) disease consisting of a Cisd2 knockout mouse. The present invention is further related to a method for screening a candidate agent for preventing or treating WFS2 disease.
摘要翻译：本发明涉及具有包括线粒体分解和功能障碍的表型的Cisd2敲除小鼠，其中Cisd2定义为SEQ ID NO：本发明还涉及由Cisd2敲除小鼠组成的Wolfram综合征2（WFS2）疾病的小鼠模型。本发明还涉及用于筛选候选药物以预防或治疗WFS2疾病的方法。

3. 发明申请

US20090282988A1 ROTATING AND DRIVING DEVICE FOR BARBECUE 审中-公开
标题翻译：旋转和驱动装置的BARBECUE
公开(公告)号：US20090282988A1
公开(公告)日：2009-11-19
申请号：US12119621
申请日：2008-05-13
申请人： Ya-Ting CHEN
发明人： Ya-Ting CHEN
IPC分类号： A47J43/18
CPC分类号： A47J37/041 , A47J37/0745
摘要： A rotating and driving device for barbecue includes a casing, a fixing base, a driving means and a shielding plate. The casing has an upright plate and an enclosing plate. An accommodating space and an opening are formed between the upright plate and the enclosing plate. The fixing base is connected to the interior of the accommodating space. The driving means is fixed to the fixing base and located between the upright plate and the fixing base. The driving means has a rotary shaft penetrating the fixing base. The shielding plate is provided with a through hole to correspond to the rotary shaft. The shielding plate is connected to one side of the fixing base away from the driving means so as to cover the opening. Via the above arrangement, electrical elements in the casing can be protected, and the leakage of electricity caused by the penetration of moisture can be efficiently prevented.
摘要翻译：用于烧烤的旋转和驱动装置包括壳体，固定基座，驱动装置和屏蔽板。外壳具有直立板和封闭板。在直立板和封闭板之间形成容纳空间和开口。固定基座连接到容纳空间的内部。驱动装置固定在固定基座上并且位于直立板和定影底座之间。驱动装置具有穿过固定基座的旋转轴。屏蔽板设置有与旋转轴对应的通孔。屏蔽板与固定底座的一侧远离驱动装置连接以覆盖开口。通过上述布置，可以保护壳体中的电气元件，并且可以有效地防止由水分渗透引起的电力泄漏。

4. 发明申请

US20080104719A1 CISD2-Knockout Mice and Uses Thereof 审中-公开
标题翻译： CISD2-Knockout小鼠及其用途
公开(公告)号：US20080104719A1
公开(公告)日：2008-05-01
申请号：US11866374
申请日：2007-10-02
申请人： Ting-Fen Tsai , Yi-Fan Chen , Shih-Feng Tsai , Ya-Ting Chen
发明人： Ting-Fen Tsai , Yi-Fan Chen , Shih-Feng Tsai , Ya-Ting Chen
IPC分类号： A01K67/027 , C12N5/00 , C12Q1/68 , G01N33/53
CPC分类号： G01N33/5088 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/035 , C07K14/47 , C12N15/8509 , C12N2503/02 , C12N2510/00 , C12N2517/02
摘要： An aging animal model and a method for screening an agent for treating or preventing aging associated phenotypes or delaying onset of aging.
摘要翻译：老化动物模型和筛选用于治疗或预防老化相关表型或延缓衰老发作的药剂的方法。

5. 发明授权

US5710007A Methods for diagnosing prostatic adenocarcinoma 失效
标题翻译：诊断前列腺腺癌的方法
公开(公告)号：US5710007A
公开(公告)日：1998-01-20
申请号：US536215
申请日：1995-09-29
申请人： Albert A. Luderer , Grant D. Carlson , Ya-Ting Chen , Thomas F. Soriano , Robert P. Thiel
发明人： Albert A. Luderer , Grant D. Carlson , Ya-Ting Chen , Thomas F. Soriano , Robert P. Thiel
IPC分类号： G01N33/53 , G01N33/573 , G01N33/574 , G01N33/537 , G01N33/542
CPC分类号： G01N33/57488 , G01N33/57434
摘要： The present invention relates to a method for diagnosing prostatic adenocarcinoma (CAP) in a male human patient without requiring a biopsy. The total prostate specific antigen (PSA) level in the blood or serum of the patient is measured. If the patient has a total PSA level of between 2.5 ng/ml and 20.0 ng/ml, then the free PSA level in the blood or serum of the patient is measured. The proportion of free PSA to total PSA is calculated. If this proportion is less than about 7%, then the patient is diagnosed as having CAP. The present method can also be used on patients that have a total PSA of at least 10.1 ng/ml, but have also had a negative prostate biopsy.
摘要翻译：本发明涉及一种男性人类患者前列腺腺癌（CAP）诊断方法，无需进行活组织检查。测量患者血液或血清中的总前列腺特异性抗原（PSA）水平。如果患者的总PSA水平在2.5ng / ml和20.0ng / ml之间，则测量患者的血液或血清中的游离PSA水平。计算游离PSA与总PSA的比例。如果该比例小于约7％，那么患者被诊断为具有CAP。本方法也可用于总PSA至少为10.1ng / ml，但也具有阴性前列腺活检的患者。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式