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1. 发明申请

US20180133162A1 TUNABLE POLYMERIC COMPOSITE COATING FOR CONTROLLED RELEASE 审中-公开
公开(公告)号：US20180133162A1
公开(公告)日：2018-05-17
申请号：US15810945
申请日：2017-11-13
申请人： XIAO YU WU , KUAN HUAN CHEN , HAO HAN CHANG , ALIREZA SHALVIRI , JASON SIU-WEI LI
发明人： XIAO YU WU , KUAN HUAN CHEN , HAO HAN CHANG , ALIREZA SHALVIRI , JASON SIU-WEI LI
IPC分类号： A61K9/50 , C09D151/02 , C08J9/26 , A61K31/277 , A61K31/522 , A61K31/554
CPC分类号： A61K9/5036 , A61K9/5047 , A61K31/277 , A61K31/522 , A61K31/554 , C08F251/02 , C08J9/26 , C08J2201/0422 , C08J2207/10 , C08J2333/12 , C09D151/02 , C08F220/06 , C08F222/385
摘要： A polymeric composite coating includes a drug release retardant polymer matrix, and pH-responsive nanoparticulate pore former. The pH-responsive pore formers function to modulate the permeability of the coating in response to pH changes which can compensate any changes in drug solubility with negligible leaching of the pore formers. The pH-responsive nanoparticulate pore formers may also function as alcohol-resistant component to the overall composite coating to resist increased solubility and permeability in presence of alcohol at 40% ethanol concentration in aqueous media. In one embodiment, the drug release retardant polymer is made of cellulose derivatives.

2. 发明申请

US20180012158A1 Increasing the Expected Availability of Fast-Delivery Offers to Customers 审中-公开
公开(公告)号：US20180012158A1
公开(公告)日：2018-01-11
申请号：US12981376
申请日：2010-12-29
申请人： Pawel M. Cholewinski , Xiao Yu Li , Kalyanaraman Prasad
发明人： Pawel M. Cholewinski , Xiao Yu Li , Kalyanaraman Prasad
IPC分类号： G06Q10/06 , G06Q30/06 , G06Q10/08
CPC分类号： G06Q10/0633 , G06Q10/08 , G06Q10/087 , G06Q30/06
摘要： A method and system for increasing the expected availability of fast-delivery offers to customers. A method may include identifying a total number of units of a plurality of items to be stored in one or more fulfillment centers. In some cases, the items may be a product or a group of products. The method may also include receiving an order forecast of expected orders for each of the plurality of items and determining, for each of the plurality of items, a portion of the expected orders that is expected to be fulfilled by the one or more fulfillment centers. The method may then include calculating based, at least in part, on the total number of units, the order forecast, and the portion of the expected orders, a target inventory of each of the plurality of items that increases an expected availability of a given delivery offer to future customers.

3. 发明授权

US09818002B1 Non-binding placement of inventory in a materials handling facility 有权
公开(公告)号：US09818002B1
公开(公告)日：2017-11-14
申请号：US12397890
申请日：2009-03-04
申请人： Jeffrey Michael Yunes , Alexei A. Kudriavstev , Xiao Yu Li , Long X. Nguyen
发明人： Jeffrey Michael Yunes , Alexei A. Kudriavstev , Xiao Yu Li , Long X. Nguyen
IPC分类号： G06G1/14
CPC分类号： G06G1/14 , G06Q10/00
摘要： In various embodiments, approaches for the placement of inventory in a materials handling facility are described. A virtual representation of a plurality of storage locations in a materials handling facility is maintained in a computer system. Each one of a plurality of inventory items is assigned to a corresponding storage location in the virtual representation. A first portion of the inventory items is stocked, and a second portion of the inventory items is unstocked. Each of the assignments is associated with a profit value. An event related to a change in state of the materials handling facility is input into the computer system. Each one of the second portion of the inventory items is reassigned in the computer system to a corresponding storage location in the virtual representation.

4. 发明授权

US09176817B2 Data management in solid state storage devices 有权
标题翻译：固态存储设备中的数据管理
公开(公告)号：US09176817B2
公开(公告)日：2015-11-03
申请号：US13617571
申请日：2012-09-14
申请人： Roy D. Cideciyan , Evangelos S. Eleftheriou , Robert Haas , Xiao-Yu Hu , Ilias Iliadis
发明人： Roy D. Cideciyan , Evangelos S. Eleftheriou , Robert Haas , Xiao-Yu Hu , Ilias Iliadis
IPC分类号： G11C29/00 , G06F11/10 , H03M13/05
CPC分类号： G06F11/108 , G06F11/1008 , G06F11/1068 , H03M13/05
摘要： A mechanism is provided for controlling a solid state storage device in which the solid state storage comprises erasable blocks each comprising a plurality of data write locations. Input data is stored in successive groups of data write locations, each group comprising write locations in a set of erasable blocks in each of a plurality of logical subdivisions of the solid state storage. The input data is error correction encoded such that each group contains an error correction code for the input data in that group. Metadata, indicating the location of input data in the solid state storage, is maintained in memory. An indication of validity of data stored in each data write location is also maintained. Prior to erasing a block, valid input data is recovered from the group containing write locations in that block. The recovered data is then re-stored as new input data.
摘要翻译：提供一种用于控制固态存储装置的机构，其中固态存储器包括每个包括多个数据写入位置的可擦除块。输入数据被存储在连续的数据写入位置组中，每个组包括在固态存储器的多个逻辑分区中的每一个中的一组可擦除块中的写入位置。输入数据被纠错编码，使得每个组包含用于该组中的输入数据的纠错码。指示固态存储器中的输入数据的位置的元数据被保存在存储器中。还保持了存储在每个数据写入位置中的数据的有效性的指示。在擦除块之前，从包含该块中的写入位置的组中恢复有效的输入数据。然后将恢复的数据重新存储为新的输入数据。

5. 发明申请

US20140262504A1 MULTIPURPOSE CANTILEVER SKIDDING FRAME 有权
标题翻译：多用途CANTILEVER滑动框架
公开(公告)号：US20140262504A1
公开(公告)日：2014-09-18
申请号：US13834816
申请日：2013-03-15
申请人： Foo Kok Seng , Matthew Quah Chin Kau , Michael John Perry , Shan Xiao Yu
发明人： Foo Kok Seng , Matthew Quah Chin Kau , Michael John Perry , Shan Xiao Yu
IPC分类号： E21B7/02 , E21B7/12
CPC分类号： E21B7/12 , E02B17/021 , E21B15/003
摘要： The present subject matter provides a multipurpose cantilever skidding frame having a first frame structure, a second frame structure and two connection beams integrally forming a rigid structure to provide longitudinal and lateral movement for an exemplary cantilever. The present subject matter also provides a drilling rig that enables a cantilever to be moved in both longitudinal and transverse directions.
摘要翻译：本主题提供了一种具有第一框架结构，第二框架结构和一体地形成刚性结构的两个连接梁的多用途悬臂滑动框架，以为示例性悬臂提供纵向和横向运动。本主题还提供了一种能够使悬臂在纵向和横向方向上移动的钻机。

6. 发明授权

US08688914B2 Promotion of partial data segments in flash cache 有权
标题翻译：在Flash缓存中促进部分数据段
公开(公告)号：US08688914B2
公开(公告)日：2014-04-01
申请号：US13286465
申请日：2011-11-01
申请人： Michael T. Benhase , Stephen L. Blinick , Evangelos S. Eleftheriou , Lokesh M. Gupta , Robert Haas , Xiao-Yu Hu , Matthew J. Kalos , Ioannis Koltsidas , Karl A. Nielsen , Roman A. Pletka
发明人： Michael T. Benhase , Stephen L. Blinick , Evangelos S. Eleftheriou , Lokesh M. Gupta , Robert Haas , Xiao-Yu Hu , Matthew J. Kalos , Ioannis Koltsidas , Karl A. Nielsen , Roman A. Pletka
IPC分类号： G06F12/00
CPC分类号： G06F3/0619 , G06F3/0646 , G06F3/0688 , G06F12/0246 , G06F12/0253 , G06F12/0811 , G06F12/0862 , G06F12/0864 , G06F12/0871 , G06F12/0897 , G06F12/122 , G06F12/127 , G06F12/128 , G06F2212/1016 , G06F2212/154 , G06F2212/222 , G06F2212/283 , G06F2212/604 , G06F2212/702 , G06F2212/7201
摘要： For efficient track destage in secondary storage in a more effective manner, for temporal bits employed with sequential bits for controlling the timing for destaging the track in a primary storage, the temporal bits and sequential bits are transferred from the primary storage to the secondary storage. The temporal bits are allowed to age on the secondary storage.
摘要翻译：为了以更有效的方式有效地在二级存储器中运行轨迹，对于与用于控制主存储器中的轨道的定时的顺序位一起使用的时间位，时间位和顺序位从主存储器传送到辅助存储器。时间位允许在辅助存储器上老化。

7. 发明授权

US08688913B2 Management of partial data segments in dual cache systems 有权
标题翻译：双缓存系统中部分数据段的管理
公开(公告)号：US08688913B2
公开(公告)日：2014-04-01
申请号：US13286454
申请日：2011-11-01
申请人： Michael T. Benhase , Stephen L. Blinick , Evangelos S. Eleftheriou , Lokesh M. Gupta , Robert Haas , Xiao-Yu Hu , Matthew J. Kalos , Ioannis Koltsidas , Roman A. Pletka
发明人： Michael T. Benhase , Stephen L. Blinick , Evangelos S. Eleftheriou , Lokesh M. Gupta , Robert Haas , Xiao-Yu Hu , Matthew J. Kalos , Ioannis Koltsidas , Roman A. Pletka
IPC分类号： G06F12/00
CPC分类号： G06F12/128 , G06F12/0811 , G06F12/0868 , G06F12/0891 , G06F12/0897 , G06F12/126 , G06F2212/1021 , G06F2212/1041 , G06F2212/222 , G06F2212/283
摘要： For movement of partial data segments within a computing storage environment having lower and higher levels of cache by a processor, a whole data segment containing one of the partial data segments is promoted to both the lower and higher levels of cache. Requested data of the whole data segment is split and positioned at a Most Recently Used (MRU) portion of a demotion queue of the higher level of cache. Unrequested data of the whole data segment is split and positioned at a Least Recently Used (LRU) portion of the demotion queue of the higher level of cache. The unrequested data is pinned in place until a write of the whole data segment to the lower level of cache completes.
摘要翻译：为了在由处理器具有较低和较高级别的高速缓存的计算存储环境中移动部分数据段，将包含部分数据段中的一个的整个数据段升级到较低级别和更高级别的高速缓存。整个数据段的请求数据被分割并定位在较高级缓存的降级队列的最近使用（MRU）部分。整个数据段的未请求的数据被分割并定位在较高级别的缓存的降级队列的最近最少使用（LRU）部分。未请求的数据被固定到位，直到整个数据段写入缓存的较低级别完成。

8. 发明授权

US08681990B2 Renewal management for data items 失效
标题翻译：数据项更新管理
公开(公告)号：US08681990B2
公开(公告)日：2014-03-25
申请号：US12411791
申请日：2009-03-26
申请人： Christian Cachin , Patrick Droz , Robert Haas , Xiao-Yu Hu , Ilias Iliadis , René A. Pawlitzek
发明人： Christian Cachin , Patrick Droz , Robert Haas , Xiao-Yu Hu , Ilias Iliadis , René A. Pawlitzek
IPC分类号： H04L9/00
CPC分类号： H04L9/0891 , G06F11/1461 , G06F21/6209 , G06F2221/2151
摘要： A system, method apparatus, and computer readable medium for managing renewal of a dynamic set of data items. Each data item has an associated renewal deadline, in a data item management system. A renewal schedule allocates to each data item a renewal interval for renewal of the data item. On addition of a new data item, if a potential renewal interval having a duration required for renewal of the data item, and having an ending at the renewal deadline for that item does not overlap a time period in the schedule during which the system is busy, the renewal schedule is automatically updated by allocating the potential renewal interval to the new data item. If the potential renewal interval does overlap a busy period, the renewal schedule is automatically updated by selecting an earlier renewal interval for at least one data item in the set.
摘要翻译：一种用于管理动态数据项集的更新的系统，方法装置和计算机可读介质。在数据项管理系统中，每个数据项具有关联的更新期限。更新计划为每个数据项分配更新数据项的更新间隔。在添加新数据项时，如果具有更新数据项所需的持续时间并且在该项目的更新期限结束的潜在更新间隔与系统正忙期间的调度中的时间段不重叠，通过将潜在的更新间隔分配给新的数据项来自动更新更新计划。如果潜在的更新间隔与繁忙期间重叠，则通过为集合中的至少一个数据项选择较早的更新间隔来自动更新更新计划。

9. 发明申请

US20140032817A1 VALID PAGE THRESHOLD BASED GARBAGE COLLECTION FOR SOLID STATE DRIVE 有权
标题翻译：基于固定状态驱动器的基于页面阈值的收集
公开(公告)号：US20140032817A1
公开(公告)日：2014-01-30
申请号：US13560065
申请日：2012-07-27
申请人： Werner Bux , Robert Haas , Xiao-Yu Hu , Ilias Iliadis
发明人： Werner Bux , Robert Haas , Xiao-Yu Hu , Ilias Iliadis
IPC分类号： G06F12/00
CPC分类号： G06F12/0246 , G06F12/0253 , G06F12/0261 , G06F2212/7205
摘要： A method for garbage collection in a solid state drive (SSD) includes determining whether the SSD is idle by a garbage collection module of the SSD; based on determining that the SSD is idle, determining a victim block from a plurality of memory blocks of the SSD; determining a number of valid pages in the victim block; comparing the determined number of valid pages in the victim block to a valid page threshold; and based on the number of valid pages in the victim block being less than the valid page threshold, issuing a garbage collection request for the victim block.
摘要翻译：一种在固态硬盘（SSD）中进行垃圾收集的方法，包括：通过SSD的垃圾收集模块确定SSD是否空闲; 基于确定所述SSD是空闲的，从所述SSD的多个存储块中确定受害者块; 确定受害者块中的有效页数; 将确定的受害者块中的有效页面数量与有效页面阈值进行比较; 并且基于受害者块中的有效页面的数量小于有效页面阈值，向受害者块发布垃圾收集请求。

10. 发明授权

US08623362B2 Anti-IL-6 antibodies 有权
标题翻译：抗IL-6抗体
公开(公告)号：US08623362B2
公开(公告)日：2014-01-07
申请号：US13524684
申请日：2012-06-15
申请人： Yan Chen , Debra Gardner , David M. Knight , Michael W. Lark , Bailin Liang , David J. Shealy , Xiao-Yu R. Song , Vedrana Stojanovic-Susulic , Raymond W. Sweet , Susan H. Tam , Sheng-Jiun Wu , Jing Yang , David Matthew Marquis , Eric Michael Smith , Alain Philippe Vasserot
发明人： Yan Chen , Debra Gardner , David M. Knight , Michael W. Lark , Bailin Liang , David J. Shealy , Xiao-Yu R. Song , Vedrana Stojanovic-Susulic , Raymond W. Sweet , Susan H. Tam , Sheng-Jiun Wu , Jing Yang , David Matthew Marquis , Eric Michael Smith , Alain Philippe Vasserot
IPC分类号： A61K39/395
CPC分类号： C07K16/248 , A61K2039/505 , A61K2039/54 , C07K2316/96 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
摘要翻译：抗IL-6抗体，包括编码至少一种抗IL-6抗体，载体，宿主细胞，转基因动物或植物的分离的核酸及其制备和使用的方法具有在诊断和/或治疗组合物中的应用，方法和设备。

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