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    • 2. 发明授权
    • Benzothiazole derivatives and methods of use
    • 苯并噻唑衍生物和使用方法
    • US5380735A
    • 1995-01-10
    • US126658
    • 1993-09-27
    • Bon Y. JungChoon S. RaYo S. RewYoung H. RheeHo S. YeoMan Y. YoonWoo B. Choi
    • Bon Y. JungChoon S. RaYo S. RewYoung H. RheeHo S. YeoMan Y. YoonWoo B. Choi
    • A01N43/78A61K31/425A61K31/428A61K31/505A61P31/04C07D277/68C07D277/72C07D277/74C07D277/82C07D417/12C07D277/70
    • C07D277/68A01N43/78C07D277/74C07D277/82C07D417/12
    • The present invention relates to a novel benzothiazole derivative of the following general formula (I) or its (E) , (Z)isomer, and processes for preparation thereof, ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 independently of one another represent hydrogen, halogen, straight and branched (C.sub.1 -C.sub.8)alkyl, (C.sub.1 -C.sub.8)halogenoalkyl or (C.sub.1 -C.sub.8)alkoxy,X represents N or CH,Y represents a group -OR.sup.4, SR.sup.5 or ##STR2## R.sup.4, R.sup.5, R.sup.6 and R.sup.7 independently of one another represent hydrogen, straight and branched (C.sub.1 -C.sub.16)alkyl, (C.sub.3 -C.sub.8)alkenyl, (C.sub.3 -C.sub.8)alkynyl, (C.sub.3 -C.sub.8)cycloalkyl, alkyl substituted with (C.sub.1 -C.sub.6)alkoxy or (C.sub.1 -C.sub.6)halogenoalkyl, or represent a substituted phenyl, phenylacyl or benzyl group wherein the possible substituent on the phenyl, phenylacyl or benzyl group includes halogen, straight and branched (C.sub.1 -C.sub.8)alkyl, (C.sub.1 -C.sub.8)alkoxy, (C.sub.3 -C.sub.8)alkenyl, (C.sub.3 -C.sub.8)alkynyl, phenoxy, nitro, cyano and a five- or six-membered heterocyclic group containing one to four nitrogen atoms.The compound of formula (I) is useful for combating phythopathogenic organisms and fungi present on animal.
    • 本发明涉及以下通式(I)或其(E),(Z)异构体的新型苯并噻唑衍生物及其制备方法,其中R1,R2和R3独立地为一 另一个代表氢,卤素,直链和支链(C1-C8)烷基,(C1-C8)卤代烷基或(C1-C8)烷氧基,X代表N或CH,Y代表基团-OR4,SR5或R4, R5,R6和R7彼此独立地表示氢,直链和支链(C1-C16)烷基,(C3-C8)烯基,(C3-C8)炔基,(C3-C8)环烷基,(C1-C6 (C1-C8)烷氧基或(C1-C6)卤代烷基,或代表取代的苯基,苯基酰基或苄基,其中苯基,苯基酰基或苄基上的可能取代基包括卤素,直链和支链(C1-C8)烷基,(C1-C8) 烷氧基,(C 3 -C 8)烯基,(C 3 -C 8)炔基,苯氧基,硝基,氰基和含有1至4个氮原子的5或6元杂环基。 式(I)化合物可用于对抗动物中存在的植物病原生物和真菌。