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1. 发明授权

US07232432B2 Particle-removing medical device and method 有权
标题翻译：除粒医疗器械及方法
公开(公告)号：US07232432B2
公开(公告)日：2007-06-19
申请号：US11035581
申请日：2005-01-14
申请人： Richard E. Fulton, III , William R. Dubrul
发明人： Richard E. Fulton, III , William R. Dubrul
IPC分类号： A61M31/00 , A61M29/00 , A61M37/00
CPC分类号： A61M25/104 , A61F2/90 , A61F2/958 , A61F2250/0067 , A61L29/16 , A61L2300/416 , A61M25/10 , A61M25/1011 , A61M2025/0057 , A61M2025/1052 , A61M2025/1081 , A61N1/306 , A61N1/327
摘要： A particle-removing medical device includes an outer, hollow tube having a tube distal end and a porous braided structure having a distal part and a proximal part. Structure, housed within the tube and having a distal end positioned distally of the tube distal end, is used to move the braided structure from a contracted condition to an expanded condition by moving the distal ends of the tube and the structure towards one another. The braided structure is constructed to inhibit particles from moving completely through the braided structure when in the expanded condition.
摘要翻译：颗粒除去医疗装置包括具有管远端的外部中空管和具有远端部分和近端部分的多孔编织结构。结构，容纳在管内并且具有远离管远端的远端，用于通过将管的远端和结构朝向彼此移动而将编织结构从收缩状态移动到扩张状态。编织结构被构造成在膨胀状态下抑制颗粒完全移动通过编织结构。

2. 发明授权

US07150712B2 Target tissue localization assembly and method 有权
标题翻译：靶组织定位装配及方法
公开(公告)号：US07150712B2
公开(公告)日：2006-12-19
申请号：US10212467
申请日：2002-08-05
申请人： Eric L. Buehlmann , Robert J. Laird , William R. Dubrul
发明人： Eric L. Buehlmann , Robert J. Laird , William R. Dubrul
IPC分类号： A61B1/00
CPC分类号： A61B18/1492 , A61B17/221 , A61B18/148 , A61B90/02 , A61B90/39 , A61B2017/00867 , A61B2017/1205 , A61B2017/22061 , A61B2017/2212 , A61B2017/2215 , A61B2018/00214 , A61B2018/00601 , A61B2018/1475 , A61B2090/3908
摘要： A target tissue localization assembly includes a radially expandable tissue anchor connected to the distal ends of an anchor assembly and an elongated anchor actuator element. A lock, engageable between the actuator element and the placement element, may be used to prevent collapse of the anchor from its radially expanded state. A sheath may be slidably mounted over the anchor assembly. The sheath and the anchor assembly may be configured to permit the sheath to move in a proximal direction, relative to the anchor assembly, past a chosen location while preventing the sheath from moving past the chosen location in a distal direction.
摘要翻译：目标组织定位组件包括连接到锚固组件的远端的可径向扩张的组织锚固件和细长的锚定致动器元件。可以使用可在致动器元件和放置元件之间接合的锁，以防止锚从其径向膨胀状态的塌陷。护套可以可滑动地安装在锚固组件上。护套和锚固组件可以被配置为允许护套相对于锚固组件在近端方向上移动经过所选择的位置，同时防止护套沿远侧方向移动经过所选择的位置。

3. 发明授权

US06530923B1 Tissue removal methods and apparatus 有权
公开(公告)号：US06530923B1
公开(公告)日：2003-03-11
申请号：US09588278
申请日：2000-06-05
申请人： William R. Dubrul , Richard E. Fulton , Robert M. Curtis
发明人： William R. Dubrul , Richard E. Fulton , Robert M. Curtis
IPC分类号： A61B1717
CPC分类号： A61B10/0266 , A61B6/502 , A61B10/02 , A61B17/221 , A61B17/3421 , A61B18/14 , A61B90/39 , A61B2090/3904 , A61B2090/3908 , A61B2090/3962
摘要： Target tissues are accessed and removed using various types of devices and methods.

4. 发明授权

US4840615A Self-sealing injection reservoir 失效
标题翻译：自密封注水池
公开(公告)号：US4840615A
公开(公告)日：1989-06-20
申请号：US167409
申请日：1988-03-14
申请人： John C. Hancock , William R. Dubrul , Charles J. Heyler, III
发明人： John C. Hancock , William R. Dubrul , Charles J. Heyler, III
IPC分类号： A61M39/02
CPC分类号： A61M39/0208 , A61M2039/0054 , A61M2039/0072 , A61M2039/0226
摘要： An injection reservoir or button is adapted for implantation beneath the skin of human and animal patients in conjuction with tissue expanders and drug delivery devices. The injection reservoir includes a base and an exterior wall which define a chamber of liquid reservoir. A duct connects the chamber with an expandable bag of the tissue expander. An elastic rubber member is affixed within the interior of the chamber to act as a sealing member. The rubber member is an inverted dome and is self-sealing to needle punctures because it has a concave interior side which is under compression as a result of having been manufactured into a substantially dome-shaped configuration and thereafter inverted. A metal guard plate is included within the interior of the chamber to guard the base against accidental puncture by an over extended hypodermic needle.
摘要翻译：注射储器或按钮适于植入人和动物患者的皮肤下面，与组织扩张器和药物递送装置结合。注入储存器包括限定液体储存室的基座和外壁。管道将腔室与组织扩张器的可膨胀袋连接。弹性橡胶构件固定在腔室的内部以用作密封构件。橡胶构件是倒置的圆顶，并且由于具有被制造成大致圆顶形构造而后反转的结果，其具有处于压缩状态的凹入内侧，因此针刺被自封闭。在室内部包括一个金属防护板，以防止基座由一个过度延长的皮下注射针引起的意外穿刺。

5. 发明申请

US20100030256A1 Medical Devices and Methods 审中-公开
标题翻译：医疗器械与方法
公开(公告)号：US20100030256A1
公开(公告)日：2010-02-04
申请号：US12477371
申请日：2009-06-03
申请人： William R. Dubrul , Richard Eustis Fulton, III
发明人： William R. Dubrul , Richard Eustis Fulton, III
IPC分类号： A61B17/221 , A61M29/00
CPC分类号： A61M25/104 , A61B6/502 , A61B10/02 , A61B10/0266 , A61B17/11 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12172 , A61B17/22004 , A61B17/221 , A61B17/32056 , A61B17/3421 , A61B18/14 , A61B90/39 , A61B90/40 , A61B2017/00287 , A61B2017/00955 , A61B2017/1107 , A61B2017/1135 , A61B2017/1205 , A61B2017/22034 , A61B2017/22067 , A61B2017/22079 , A61B2017/2212 , A61B2017/2215 , A61B2018/1407 , A61B2090/3904 , A61B2090/3908 , A61B2090/3962 , A61M25/0119
摘要： Medical devices include a catheter, a catheter/dilator assembly, an occluder, a rapid exchange dilator assembly, a funnel catheter, an anastomotic medical device, and associated methods.
摘要翻译：医疗装置包括导管，导管/扩张器组件，闭塞器，快速交换扩张器组件，漏斗导管，吻合医疗装置和相关方法。

6. 发明授权

US07479152B2 Target tissue localization device 失效
标题翻译：靶组织定位装置
公开(公告)号：US07479152B2
公开(公告)日：2009-01-20
申请号：US10885910
申请日：2004-07-06
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M29/00
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device includes a tubular mesh anchor element that is secured to a placement device. In use, the localization device is passed through the patient's skin to the target tissue, creating a tissue track. The tubular mesh anchor element is located at the target tissue and expanded from a contracted to an expanded configuration. Methods for localizing a lymph node are also described. After determining the position of the lymph node, a localization device, which includes an anchor element, is localized near or within the lymph node. The anchor element is then expanded.
摘要翻译：目标组织定位装置包括固定到放置装置的管状网状锚定元件。在使用中，定位装置通过患者的皮肤传递到目标组织，形成组织轨道。管状网状锚定元件位于目标组织处并且从收缩状态扩展到扩张构型。还描述了用于定位淋巴结的方法。在确定淋巴结的位置之后，包括锚定元件的定位装置位于淋巴结附近或内部。然后锚定元素被扩展。

7. 发明授权

US06758855B2 Target tissue localization device 有权
标题翻译：靶组织定位装置
公开(公告)号：US06758855B2
公开(公告)日：2004-07-06
申请号：US10134802
申请日：2002-04-29
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M2900
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device (28) has outer and inner members (30, 32) which are longitudinally movable relative to one another. An anchor (42) is secured to the outer and inner members and is movable from a radially-contracted configuration to a radially-expanded configuration. The anchor may be a tubular mesh anchor. The anchor may have a sufficiently large cross-sectional area when in the radially-expanded configuration to substantially eliminate inadvertent dislodgment of the anchor once radially-expanded. In use, the location of the target tissue (56) is determined and the distal end of the localization device is passed through the patient's skin (58) and to the target tissue to create a tissue track (60) between the patient's skin and the target tissue. The target tissue includes near and far sides (62, 64). The anchor element, located at the target tissue is expanded to an expanded configuration. The method the anchor element may be located on the far side of the target tissue. The localization device may be selected with an anchor which is palpable for relocation of the target tissue.
摘要翻译：目标组织定位装置（28）具有能够相对于彼此纵向移动的外部构件（30）和内部构件（32）。锚固件（42）固定到外部构件和内部构件，并且可以从径向缩小构造移动到径向扩张构型。锚可以是管状网锚。当处于径向展开的构型中时，锚具可以具有足够大的横截面面积，以基本上消除锚固件一旦径向膨胀的无意中的移动。在使用中，确定目标组织（56）的位置，并且定位装置的远端通过患者的皮肤（58）和目标组织，以在患者的皮肤和患者的皮肤之间产生组织轨迹（60）目标组织。目标组织包括近侧和远侧（62,64）。位于目标组织的锚定元件被扩展到扩展构型。锚定元件可以位于目标组织的远侧上的方法。定位装置可以用可触及目标组织重新定位的锚点来选择。

8. 发明授权

US06602204B2 Intraoperative tissue treatment methods 有权
标题翻译：术中组织治疗方法
公开(公告)号：US06602204B2
公开(公告)日：2003-08-05
申请号：US09844661
申请日：2001-04-27
申请人： William R. Dubrul , Richard E. Fulton , Robert M. Curtis
发明人： William R. Dubrul , Richard E. Fulton , Robert M. Curtis
IPC分类号： A61B1000
CPC分类号： A61B10/0266 , A61B6/502 , A61B10/02 , A61B17/221 , A61B17/3421 , A61B18/14 , A61B90/39 , A61B2090/3904 , A61B2090/3908 , A61B2090/3962
摘要： Intraoperative tissue treatment methods are used following the removal of target tissue, e.g. diseased tissue, from a target site, e.g. within a patient's breast, leaving access to the target site. In one method an expandable element is introduced into and expanded within a void at the target site. If all of the target tissue was not removed, then a layer of tissue at least partially surrounding the expanded element is removed from the patient, preferably in a substantially intact form. In a second method the suction inlet of a suction device is in fluid communication with the void. If all of the target tissue has not been removed, at least a portion of the collapsed tissue is removed from the patient and analyzed. With a third method, a flexible implant is passed through the sheath and into the void to at least substantially fill the void.
摘要翻译：术后组织治疗方法是在去除靶组织后使用的。患病组织，来自靶位点，例如。在患者的乳房内，进入目标部位。在一种方法中，可扩张元件被引入到目标位置的空隙内并扩大。如果没有去除所有的目标组织，则至少部分地围绕扩张的元件的组织层从患者中移除，优选以基本上完整的形式。在第二种方法中，抽吸装置的吸入口与空隙流体连通。如果所有的目标组织都没有被去除，则从患者身上移除至少一部分塌陷的组织并进行分析。利用第三种方法，将柔性植入物穿过护套并进入空隙以至少基本上填充空隙。

9. 发明授权

US5392766A System and method for cleaning viewing scope lenses 失效
标题翻译：清洁观察镜片的系统和方法
公开(公告)号：US5392766A
公开(公告)日：1995-02-28
申请号：US132544
申请日：1993-10-06
申请人： Steven Masterson , William R. Dubrul
发明人： Steven Masterson , William R. Dubrul
IPC分类号： A61B1/12 , A61B1/313 , A61B1/00
CPC分类号： A61B1/0008 , A61B1/00135 , A61B1/126 , A61B1/313 , A61B2017/3441
摘要： Percutaneous access devices are provided with cleaning elements for in situ cleaning of viewing scope lenses during surgical procedures. The access devices will comprise a cannula having an access lumen therethrough. The cleaning element will be disposed at or near the distal end of the cannula, preferably over or across a distal port of the cannula. The cleaning element may comprise an elastomeric membrane, an open cell foam pad, one or more articulated plates, or a combination thereof. Cleaning of the lens of the viewing scope is effected by moving the lens between positions proximal of and distal to the cleaning element.
摘要翻译：经皮进入装置设置有清洁元件，用于在外科手术过程中原位清洁观察镜片。进入装置将包括具有通过其的进入腔的套管。清洁元件将设置在套管的远端处或附近，优选地在插管的远端上方或跨越套管的远端。清洁元件可以包括弹性体膜，开孔泡沫垫，一个或多个铰接板或其组合。通过在清洁元件的近侧和远端之间移动透镜来实现对观察镜的透镜的清洁。

10. 发明授权

US4738657A Self-sealing injection reservoir 失效
标题翻译：自密封注水池
公开(公告)号：US4738657A
公开(公告)日：1988-04-19
申请号：US781965
申请日：1985-09-30
申请人： John C. Hancock , William R. Dubrul , Charles J. Heyler, III
发明人： John C. Hancock , William R. Dubrul , Charles J. Heyler, III
IPC分类号： A61M39/02 , A61M25/00 , A61B19/00
CPC分类号： A61M39/0208
摘要： An injection reservoir or button is disclosed which is adapted for implantation beneath the skin of human and animal patients in conjunction with tissue expanders and drug delivery devices. The injection reservoir includes a base and an exterior wall which define a chamber or liquid reservoir. A suitable duct connects the chamber with an expandable bag of the tissue expander. An elastic rubber member is affixed within the interior of the chamber in a configuration wherein its side abutting the chamber is in compression, thereby rendering the member self-sealing to punctures by a hypodermic needle. A metal guard plate is included within the interior of the chamber to guard the base against accidental puncture by an over-extended hypodermic needle.
摘要翻译：公开了一种注射储器或按钮，其适于与组织扩张器和药物递送装置一起在人和动物患者的皮肤下植入。注入储存器包括限定腔室或液体储存器的底座和外壁。合适的管道将腔室与组织扩张器的可膨胀袋连接。弹性橡胶构件以这样的构造固定在腔室内部，其中其邻接室的侧面处于压缩状态，从而使构件自密封地被皮下注射针穿刺。在室内部包括一个金属防护板，用于防止基座由一个过度延伸的皮下注射针引起的意外穿刺。

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