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    • 4. 发明授权
    • Process
    • 处理
    • US5952524A
    • 1999-09-14
    • US65270
    • 1998-04-23
    • Victor EliuWerner KanertAdriano IndoleseIan John FletcherJulia VolkelAnita Schnyder
    • Victor EliuWerner KanertAdriano IndoleseIan John FletcherJulia VolkelAnita Schnyder
    • B01J31/22C07B37/04C07B61/00C07C2/86C07C15/52C07C17/263C07C25/24C07C67/333C07C69/76C07C201/12C07C205/06C07C303/22C07C303/32C07C303/34C07C309/29C07C309/32C09B57/00C11D3/42C07C321/00
    • C07C303/32C07C303/22
    • The present invention provides a process for the production of a compound of formula: ##STR1## in which X and Y, independently, are hydrogen, halogen, NO.sub.2, CF.sub.3, CN, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, COO--C.sub.1 -C.sub.4 alkyl, CO--C.sub.1 -C.sub.4 alkyl, NH--(C.sub.1 -C.sub.4 alkyl), N(C.sub.1 -C.sub.4 alkyl).sub.2, NH(C.sub.1 -C.sub.4 alkyl-OH), N(C.sub.1 -C.sub.4 alkyl-OH).sub.2, COOH or SO.sub.3 H or an ester or amide thereof, or COOM or SO.sub.3 M in which M is Na, K, Ca, Mg, ammonium, mono-, di-, tri- or tetra-C.sub.1 -C.sub.4 alkylammonium, mono-, di- or tri-hydroxyalkylammonium or ammonium that is di- or tri-substituted with a mixture of C.sub.1 -C.sub.4 alkyl and C.sub.1 -C.sub.4 hydroxyalkyl groups;Z is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, CF.sub.3, halogen (F, Cl, Br, I), SO.sub.3 H or SO.sub.3 M in which M has its previous significance; andn is 1 or 2; comprisingA) reacting a diazonium compound having the formula: ##STR2## in which X and n have their previous significance and G is a counter ion, with ethylene in the presence of an inorganic or organic palladium compound, or a mixture thereof, as catalyst-precursor, to produce a compound having the formula: ##STR3## in which X and n have their previous significance; and B) reacting 2 moles of the compound of formula (3) with 1 mole of a compound having the formula: ##STR4## In which Z has its previous significance and each R.sub.1 is the same and is a bromine or iodine atom, in the presence of an inorganic or organic palladium compound, or a mixture thereof, as catalyst-precursor, to produce a compound having the formula (1). The compounds of formula (1) are useful as fluorescent whitening agents.
    • 本发明提供一种制备下式化合物的方法:其中X和Y独立地是氢,卤素,NO 2,CF 3,CN,C 1 -C 4烷基,C 1 -C 4烷氧基,COO-C 1 -C 4烷基,CO- C 1 -C 4烷基,NH-(C 1 -C 4烷基),N(C 1 -C 4烷基)2,NH(C 1 -C 4烷基-OH),N(C 1 -C 4烷基-OH)2,COOH或SO 3 H或其酯或酰胺, COOM或SO 3 M,其中M是Na,K,Ca,Mg,铵,一,二,三或四-C 1 -C 4烷基铵,二 - 或三 - 被C1-C4烷基和C1-C4羟烷基的混合物取代; Z为氢,C1-C4烷基,C1-C4烷氧基,CF3,卤素(F,Cl,Br,I),SO3H或SO3M,其中M具有以前的意义; n为1或2; 包括:A)使无机或有机钯化合物或其混合物作为催化剂前体的具有下式的重氮化合物:其中X和n具有其先前的含义,G是抗衡离子,与乙烯反应, 以产生具有下式的化合物:其中X和n具有其先前的含义; 和B)使2摩尔式(3)化合物与1摩尔具有下式的化合物反应:其中Z具有其先前的含义,并且每个R 1相同且为溴或碘原子,在 无机或有机钯化合物或其混合物作为催化剂前体,以制备具有式(1)的化合物。 式(1)的化合物可用作荧光增白剂。