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    • 5. 发明申请
    • Oligonucleotide probe sets and uses thereof
    • 寡核苷酸探针组及其用途
    • US20050142589A1
    • 2005-06-30
    • US10970760
    • 2004-10-21
    • Ron BroideAlain TrembleauWarren YoungJohn MorrisonFloyd Bloom
    • Ron BroideAlain TrembleauWarren YoungJohn MorrisonFloyd Bloom
    • C12Q1/68G01N20060101
    • C12Q1/6816C12Q1/6841C12Q2545/113C12Q2537/143
    • The present invention relates to methods and probes for detecting relative levels of multiple nucleic acid sequences of interest. The invention includes a method to detect the relative amounts of at least two target nucleic acid sequences in at least one sample by use of a corresponding set of detectably labelled oligonucleotide probes for each of the at least two target nucleic acid sequences, and detecting the hybridization of each of the corresponding sets of oligonucleotide probes to its respective target nucleic acid sequence. The invention also includes a method to detect the relative amounts of multiple target messenger RNAs in at least one microscopy sample by in situ hybridization using sets of oligonucleotide probes. Also disclosed are methods to provide corresponding sets of oligonucleotide probes for target nucleic acid sequences.
    • 本发明涉及用于检测感兴趣的多个核酸序列的相对水平的方法和探针。 本发明包括通过使用针对至少两个靶核酸序列中的每一个的相应的一组可检测标记的寡核苷酸探针来检测至少两个靶核酸序列在至少一个样品中的相对量的方法,并检测杂交 每个对应的寡核苷酸探针组合到其各自的靶核酸序列。 本发明还包括通过使用寡核苷酸探针的组合通过原位杂交来检测至少一个显微镜样品中多个靶信使RNA的相对量的方法。 还公开了为靶核酸序列提供相应组的寡核苷酸探针的方法。
    • 9. 发明授权
    • Sweat-absorbing headgear
    • 吸汗头盔
    • US06546563B2
    • 2003-04-15
    • US09906301
    • 2001-07-16
    • Warren Young
    • Warren Young
    • A42B122
    • A42B1/22A42C5/02
    • A sweat-absorbing headgear includes a headgear body having a ring portion adapted to extend around the head of a wearer. The ring portion includes a woven elastic band section and is changeable in size due to stretchable and contractible characteristics of the woven elastic band section. The woven elastic band section is stretchable along a longitudinal direction thereof, and includes a plurality of fiber bundles which extend along the longitudinal direction and which are spaced apart transversely. The fiber bundles are stretched when the woven elastic band section is stretched, and form a plurality of sweat-absorbing fiber tufts projecting from an inner surface of the woven elastic band section when the latter returns to a normally contracted state.
    • 吸汗头包括具有适于围绕佩戴者的头部延伸的环部分的头带本体。 环形部分包括编织弹性带部分,并且由于编织弹性带部分的可拉伸和收缩特性而可改变尺寸。 编织弹性带部分沿着其纵向方向是可拉伸的,并且包括沿着纵向方向延伸并且横向隔开的多个纤维束。 当织造弹性带部分被拉伸时,纤维束被拉伸,并且当织造弹性带部分恢复到正常收缩状态时形成从编织弹性带部分的内表面突出的多个吸汗纤维簇。