专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050262588A1 Thioesterase-related nucleic acid sequences and methods of use for the production of plants with modified fatty acid composition 审中-公开
标题翻译：硫酯酶相关核酸序列和用于生产具有改性脂肪酸组成的植物的方法
公开(公告)号：US20050262588A1
公开(公告)日：2005-11-24
申请号：US10518752
申请日：2003-06-20
申请人： Katayoon Dehesh , Vic Knauf
发明人： Katayoon Dehesh , Vic Knauf
IPC分类号： A01H5/00 , A01H1/00 , C12N5/04 , C12N5/10 , C12N9/04 , C12N9/16 , C12N15/09 , C12N15/82
CPC分类号： C12N15/8247 , C12N9/16
摘要： The present invention is directed to nucleic acid molecules and nucleic acid constructs, and other agents associated with fatty acid synthesis, particularly the ratios of saturated and unsaturated fats. Moreover, the present invention is directed to plants incorporating such agents where the plants exhibit altered ratios of saturated and unsaturated fats. In particular, the present invention is directed to plants incorporating such agents where the plants exhibit altered levels of saturated and unsaturated fatty acids.
摘要翻译：本发明涉及核酸分子和核酸构建体以及与脂肪酸合成相关的其它试剂，特别是饱和和不饱和脂肪的比例。此外，本发明涉及掺入这些试剂的植物，其中植物表现出改变的饱和和不饱和脂肪的比例。特别地，本发明涉及掺入这种试剂的植物，其中植物表现出改变水平的饱和和不饱和脂肪酸。

2. 发明申请

US20070016981A1 Plant desaturases - compositions and uses 失效
标题翻译：植物去饱和酶 - 组合物和用途
公开(公告)号：US20070016981A1
公开(公告)日：2007-01-18
申请号：US11415867
申请日：2006-05-02
申请人： Gregory Thompson , Vic Knauf
发明人： Gregory Thompson , Vic Knauf
IPC分类号： A01H1/00 , C12N9/04 , C12N15/82 , C12N5/04
CPC分类号： C12N9/0083 , A23D9/00 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12Y114/19002
摘要： By this invention, compositions and methods of use of plant desaturase enzymes, especially Δ-9 desaturases, are provided. Of special interest are methods and compositions of amino acids and nucleic acid sequences related to biologically active plant desaturases as well as sequences, especially nucleic acid sequences, which are to be used as probes, vectors for transformation or cloning intermediates. Biologically active sequences may be found in a sense or anti-sense orientation as to transcriptional regulatory regions found in various constructs.
摘要翻译：通过本发明，提供了植物去饱和酶，特别是Δ-9去饱和酶的组合物和方法。特别感兴趣的是与生物活性植物去饱和酶相关的氨基酸和核酸序列的方法和组合物以及用作探针的序列，特别是核酸序列，用于转化或克隆中间体的载体。关于在各种构建体中发现的转录调控区域，可以在有义或反义方向上发现生物活性序列。

3. 发明申请

US20070067870A1 Safflower with elevated gamma-linolenic acid 有权
标题翻译：红花与γ-亚麻酸升高
公开(公告)号：US20070067870A1
公开(公告)日：2007-03-22
申请号：US11438951
申请日：2006-05-22
申请人： Vic Knauf , Christine Shewmaker , Frank Flider , Donald Emlay , Eric Rey
发明人： Vic Knauf , Christine Shewmaker , Frank Flider , Donald Emlay , Eric Rey
IPC分类号： A01H1/00 , C12N15/82
CPC分类号： C12N9/0083 , C12N15/8247
摘要： The present invention relates to compositions and methods for preparing gamma-linoleic acid (GLA) in safflower plants, particularly from seeds of safflower. Nucleic acid sequences and constructs encoding one or more fatty acid desaturase sequences are used to generate transgenic safflower plants that contain and express one or more of these sequences and produce high levels of GLA in safflower seeds. Provided are transgenic safflower plants and seeds that produce high levels of GLA. Additionally provided are oils produced from seeds of this invention. The invention also relates to methods of treating a variety of diseases including nervous system disorders, inflammatory conditions, cancer and cardiovascular disorders using the oils of this invention.
摘要翻译：本发明涉及用于在红花植物，特别是红花种子中制备γ-亚油酸（GLA）的组合物和方法。编码一种或多种脂肪酸去饱和酶序列的核酸序列和构建体用于产生含有并表达这些序列中的一种或多种并在红花种子中产生高水平GLA的转基因红花植物。提供产生高水平GLA的转基因红花植物和种子。另外提供的是由本发明的种子生产的油。本发明还涉及使用本发明的油治疗多种疾病的方法，包括神经系统疾病，炎性病症，癌症和心血管疾病。

4. 发明授权

US5955329A Engineering plant thioesterases for altered substrate specificity 失效
标题翻译：工程植物硫酯酶改变底物特异性
公开(公告)号：US5955329A
公开(公告)日：1999-09-21
申请号：US440845
申请日：1995-05-15
申请人： Ling Yuan , Katayoon Dehesh , Jean Kridl , Vic Knauf
发明人： Ling Yuan , Katayoon Dehesh , Jean Kridl , Vic Knauf
IPC分类号： C12N9/16 , C12N15/82 , C12N15/00 , C07H21/04
CPC分类号： C12N15/8247 , C12N9/16
摘要： Methods of altering substrate specificity of plant acyl-ACP thioesterases, and engineered plant acyl-ACP thioesterases so produced are provided. The C-terminal two thirds portion of plant thioesterases is identified as desirable for such modifications. DNA sequences and constructs for expression of engineered thioesterases, as well as the novel thioesterases produced therefrom are also provided. Such DNA sequences may be used for expression of the engineered thioesterases in host cells, particularly seed cells of oilseed crop plants, for the modification of fatty acid composition. A C12 preferring plant acyl-ACP thioesterase described herein may be altered to obtain a plant thioesterase having approximately equal activity on C14 and C12 substrates. Further modification of the C12 enzyme yields a thioesterase having greater activity on C14 as compared to C12 substrates. Also provided in the instant invention are novel plant acyl-ACP thioesterase sequences from Cuphea palustris and mangosteen (Garcinia mangifera), which demonstrate desirable thioesterase activity profiles for plant genetic engineering applications.
摘要翻译：提供了改变植物酰基-ACP硫酯酶底物特异性的方法，以及如此制备的工程化植物酰基-ACP硫酯酶。植物硫酯酶的C末端三分之二部分被鉴定为对于这种修饰是理想的。还提供了用于表达工程化硫酯酶的DNA序列和构建体，以及由其产生的新的硫酯酶。这样的DNA序列可用于在宿主细胞，特别是油籽作物植物的种子细胞中表达改性的硫酯酶，用于改变脂肪酸组成。可以改变本文所述的C12优选植物酰基-ACP硫酯酶以获得对C14和C12底物具有大致相同活性的植物硫酯酶。与C12底物相比，C12酶的进一步修饰产生对C14具有更大活性的硫酯酶。本发明还提供了来自Cuphea palustris和山竹（Garcinia mangifera）的新型植物酰基-ACP硫酯酶序列，其显示用于植物基因工程应用的期望的硫酯酶活性谱。

5. 发明授权

US5453566A Antisense regulation of gene expression in plant/cells 失效
标题翻译：植物/细胞中基因表达的反义调控
公开(公告)号：US5453566A
公开(公告)日：1995-09-26
申请号：US750505
申请日：1991-08-27
申请人： Christine K. Shewmaker , Jean C. Kridl , William R. Hiatt , Vic Knauf
发明人： Christine K. Shewmaker , Jean C. Kridl , William R. Hiatt , Vic Knauf
IPC分类号： C12N9/24 , C12N15/113 , C12N15/82 , C12N15/84 , A01H5/00 , C07H21/04 , C12N5/14 , C12N15/64
CPC分类号： C12N15/8216 , C12N15/1137 , C12N15/8218 , C12N9/2402 , C12Y302/01015 , C12N2310/111 , Y10S47/01
摘要： Regulation of expression of genes encoded for in plant cell genomes is achieved by integration of a gene under the transcriptional control of a promoter which is functional in the host and in which the transcribed strand of DNA is complementary to the strand of DNA that is transcribed from the endogenous gene(s) one wishes to regulate. The integrated gene, referred to as antisense, provides an RNA sequence capable of binding to naturally existing RNAs, exemplified by polygalacturonase, and inhibiting their expression, where the anti-sense sequence may bind to the coding, non-coding, or both, portions of the RNA. The antisense construction may be introduced into the plant cells in a variety of ways and be integrated into the plant genome for inducible or constitutive transcription of the antisense sequence. A wide variety of plant cell properties may be modified by employing this technique.
摘要翻译：在植物细胞基因组中编码的基因的表达的调节是通过在宿主的功能的启动子的转录控制下整合基因来实现的，其中DNA的转录链与DNA转录的DNA互补内源基因希望调节。称为反义的整合基因提供了能够结合天然存在的RNA的RNA序列，例如由多聚半乳糖醛酸酶示例，并抑制其表达，其中反义序列可以结合编码，非编码或两者部分的RNA。反义构建可以以各种方式引入植物细胞中，并被整合到植物基因组中，用于诱导或组成型的反义序列的转录。通过采用这种技术可以改变各种各样的植物细胞特性。

6. 发明授权

US4801540A PG gene and its use in plants 失效
标题翻译： PG基因及其在植物中的应用
公开(公告)号：US4801540A
公开(公告)日：1989-01-31
申请号：US201
申请日：1987-01-02
申请人： William R. Hiatt , Raymond E. Sheehy , Christine K. Shewmaker , Jean C. Kridl , Vic Knauf
发明人： William R. Hiatt , Raymond E. Sheehy , Christine K. Shewmaker , Jean C. Kridl , Vic Knauf
IPC分类号： C12N9/24 , C12N15/113 , C12N15/82 , C12N15/00 , C07H15/12 , C12N5/00 , C12P21/00
CPC分类号： C12N15/1137 , C12N15/8216 , C12N15/8218 , C12N9/2402 , C12Y302/01015 , C12N2310/111
摘要： Polygalacturonase DNA sequence and its use in modulating polygalacturonase expression in plant cells. DNA constructions are provided. The transit peptide finds use with heterologous peptides.
摘要翻译：多聚半乳糖醛酸酶DNA序列及其在植物细胞中调节多聚半乳糖醛酸酶表达的用途。提供DNA构建体。转运肽可与异源肽一起使用。

7. 发明申请

US20060037112A1 Tomatoes having reduced polygalacturonase activity caused by non-transgenic mutations in the polygalacturonase gene. 有权
标题翻译：具有由多聚半乳糖醛酸酶基因中的非转基因突变引起的多聚半乳糖醛酸酶活性降低的番茄。
公开(公告)号：US20060037112A1
公开(公告)日：2006-02-16
申请号：US11246793
申请日：2005-10-07
申请人： Claire McCallum , Ann Slade , Trenton Colbert , Vic Knauf , Susan Hurst
发明人： Claire McCallum , Ann Slade , Trenton Colbert , Vic Knauf , Susan Hurst
IPC分类号： A01H5/00 , C12N5/04
CPC分类号： C07H21/04 , C12N9/2402 , C12Y302/01015
摘要： A series of independent non-transgenic mutations found in the fruit PG gene of tomato; tomato plants having these mutations in their fruit PG gene; and a method of creating and identifying similar and/or additional mutations in the PG gene by screening pooled and/or individual tomato plants. The tomato plants of the present invention exhibit reduced PG enzyme activity and fruit that soften more slowly post harvest without having the inclusion of foreign nucleic acids in their genomes.
摘要翻译：在番茄果实PG基因中发现一系列独立的非转基因突变; 在其果实PG基因中具有这些突变的番茄植物; 以及通过筛选合并的和/或个体番茄植物来产生和鉴定PG基因中相似和/或另外的突变的方法。本发明的番茄植物显示降低的PG酶活性和果实，其收获后软化得更慢，而不会在其基因组中包含外来核酸。

8. 发明授权

US5759829A Antisense regulation of gene expression in plant cells 失效
标题翻译：植物细胞中基因表达的反义调控
公开(公告)号：US5759829A
公开(公告)日：1998-06-02
申请号：US463213
申请日：1995-06-05
申请人： Christine K. Shewmaker , Jean C. Kridl , William R. Hiatt , Vic Knauf
发明人： Christine K. Shewmaker , Jean C. Kridl , William R. Hiatt , Vic Knauf
IPC分类号： C12N9/24 , C12N15/113 , C12N15/82 , C12N15/84 , A01H1/02 , A01H5/00 , C12N15/29
CPC分类号： C12N15/8216 , C12N15/1137 , C12N15/8218 , C12N9/2402 , C12Y302/01015 , C12N2310/111 , Y10S47/01
摘要： Regulation of expression of genes encoded for in plant cell genomes is achieved by integration of a gene under the transcriptional control of a promoter which is functional in the host and in which the transcribed strand of DNA is complementary to the strand of DNA that is transcribed from the endogenous gene(s) one wishes to regulate. The integrated gene, referred to as antisense, provides an RNA sequence capable of binding to naturally existing RNAs, exemplified by polygalacturonase, and inhibiting their expression, where the anti-sense sequence may bind to the coding, non-coding, or both, portions of the RNA. The antisense construction may be introduced into the plant cells in a variety of ways and be integrated into the plant genome for inducible or constitutive transcription of the antisense sequence. A wide variety of plant cell properties may be modified by employing this technique.
摘要翻译：在植物细胞基因组中编码的基因的表达的调节是通过在宿主的功能的启动子的转录控制下整合基因来实现的，其中DNA的转录链与DNA转录的DNA互补内源基因希望调节。称为反义的整合基因提供了能够结合天然存在的RNA的RNA序列，例如由多聚半乳糖醛酸酶示例，并抑制其表达，其中反义序列可以结合编码，非编码或两者部分的RNA。反义构建可以以各种方式引入植物细胞中，并被整合到植物基因组中，用于诱导或组成型的反义序列的转录。通过采用这种技术可以改变各种各样的植物细胞特性。

9. 发明授权

US5107065A Anti-sense regulation of gene expression in plant cells 失效
标题翻译：植物细胞中基因表达的反义调节
公开(公告)号：US5107065A
公开(公告)日：1992-04-21
申请号：US240408
申请日：1988-08-30
申请人： Christine K. Shewmaker , Jean C. Kridl , William R. Hiatt , Vic Knauf
发明人： Christine K. Shewmaker , Jean C. Kridl , William R. Hiatt , Vic Knauf
IPC分类号： C12N9/24 , C12N15/113 , C12N15/82
CPC分类号： C12N15/1137 , C12N15/8216 , C12N15/8218 , C12N9/2402 , C12Y302/01015 , C12N2310/111
摘要： Regulation of expression of genes encoded for in plant cell genomes is achieved by integration of a gene under the transcriptional control of a promoter which is functional in the host and in which the transcribed strand of DNA is complementary to the strand of DNA that is transcribed from the endogenous gene(s) one wishes to regulate. The integrated gene, referred to as anti-sense, provides an RNA sequence capable of binding to naturally existing RNAs, exemplified by polygalacturonase, and inhibiting their expression, where the anti-sense sequence may bind to the coding, non-coding, or both, portions of the RNA. The antisense construction may be introduced into the plant cells in a variety of ways and be integrated into the plant genome for inducible or constitutive transcription of the anti-sense sequence. A wide variety of plant cell properties may be modifed by employing this technique.The pCGN978xK12 was deposited at the A.T.C.C. on Mar. 25, 1986, and given Accession No. 67064 and pCGN1401 was deposited on Oct. 7, 1986 at the A.T.C.C. and given Accession No. 67227.
摘要翻译：在植物细胞基因组中编码的基因的表达的调节是通过在宿主的功能的启动子的转录控制下整合基因来实现的，其中DNA的转录链与DNA转录的DNA互补内源基因希望调节。称为反义的整合基因提供了能够结合天然存在的RNA的RNA序列，例如由多聚半乳糖醛酸脱水酶，并抑制其表达，其中反义序列可以结合编码，非编码或两者，部分RNA。反义结构可以以各种方式引入植物细胞中，并且整合到植物基因组中以诱导或组成型转录反义序列。可以通过采用这种技术来改变各种各样的植物细胞特性。 pCGN978xK12保藏在A.T.C.C. 1986年3月25日，加拿大号67064和pCGN1401于1986年10月7日在A.T.C.C. 并提供登记号67227。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式