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1. 发明授权

US3793149A Cell-bound keratinolytic enzymes or trichophyton mentagrophytes and process therefor 失效
标题翻译：细胞胆固醇酯酶或三烯酸甘油酯及其过程
公开(公告)号：US3793149A
公开(公告)日：1974-02-19
申请号：US3793149D
申请日：1972-01-03
申请人： UNIV TEMPLE
发明人： BLANK F , YU R
IPC分类号： C12N9/58 , C07G7/02
CPC分类号： C12N9/58 , Y10S435/815 , Y10S435/911
摘要： Two cell-bound keratinases are produced by incubating T. mentagrophytes for several days in growth medium, at a pH of 7.8, containing horse hair, magnesium salt, thiamine, pyridoxine and inositol. Preferably, glucose is also included. These keratinases are extracted from the fungus mycelium after filtering off the growth media, partially purifying the enzymes by adsorbing them separately on diethylaminoethyl cellulose and carboxymethyl cellulose. The first enzyme which is eluted from the diethylaminoethyl cellulose and purified by molecular sieves has a molecular weight of 440,000. The second enzyme which is eluted from the carboxymethyl cellulose and purified by molecular sieves has a molecular weight of 20,300. Physicochemical properties as well as their keratinolytic activities have been determined.
摘要翻译：通过在含有马毛，镁盐，硫胺素，吡哆醇和肌醇的pH为7.8的生长培养基中温育T. mentagrophytes数天来产生两种细胞结合的角蛋白酶。优选还包括葡萄糖。过滤出生长培养基后，从真菌菌丝体中提取这些角质化酶，通过将其分别吸附在二乙基氨基乙基纤维素和羧甲基纤维素上来部分纯化酶。从二乙基氨基乙基纤维素洗脱并用分子筛纯化的第一种酶的分子量为44万。从羧甲基纤维素洗脱并用分子筛纯化的第二种酶的分子量为20,300。已经确定了物理化学性质以及它们的角质溶解活性。

2. 发明授权

US3678922A Dilution method and apparatus for measurement of fluid flow rate 失效
标题翻译：用于测量流体流量的方法和装置
公开(公告)号：US3678922A
公开(公告)日：1972-07-25
申请号：US3678922D
申请日：1971-01-14
申请人： UNIV TEMPLE
发明人： PHILIPS CHARLES M , SANMARCO MIGUEL E
IPC分类号： A61B5/0275 , G01F1/68 , G01F1/704 , A61B5/02
CPC分类号： G01F1/704 , A61B5/0275 , G01F1/68
摘要： A dilution technique for measuring fluid flow rate within a circulating fluid system is disclosed, comprising continuous processing of a response signal following injection of an injectate into the fluid system, the process being terminated at a cut off point which is determined in terms of the peak of the response signal. The cut off point of the response signal is determined to compensate for error normally introduced due to recirculation. Apparatus is disclosed for carrying out the steps of the process, comprising an integrator-divider for processing the response signal, a peak detector and comparator for terminating the signal processing at the cut off point, and a lock in amplifier to hold the computed result during the period of recirculation. The method and apparatus for particularly applicable to thermal dilution and dye dilution measurements of blood flow rate.
摘要翻译：公开了一种用于测量循环流体系统内的流体流速的稀释技术，包括在将注射器注射到流体系统中之后连续处理响应信号，该过程在切断点处终止，该切断点根据峰值的响应信号。确定响应信号的截止点以补偿由于再循环而通常引入的误差。公开了用于执行该过程的步骤的装置，包括用于处理响应信号的积分器分频器，用于终止在截止点处的信号处理的峰值检测器和比较器，以及用于保持计算结果的锁定循环的时期。用于特别适用于血液流速的热稀释和染料稀释测量的方法和装置。

3. 发明授权

US3426136A Method for the treatment of cardiac dysrhythmias with sodium thioglycollate 失效
标题翻译：用硫酸钠处理心脏脑血管病的方法
公开(公告)号：US3426136A
公开(公告)日：1969-02-04
申请号：US3426136D
申请日：1966-11-17
申请人： UNIV TEMPLE
发明人： TANSY MARTIN F
IPC分类号： A61K31/265 , A61K25/00 , A61K27/00
CPC分类号： A61K31/265 , Y10S514/821

4. 发明授权

US3827780A Stable anil-type nematic liquid crystals 失效
标题翻译：稳定的水性液体水晶
公开(公告)号：US3827780A
公开(公告)日：1974-08-06
申请号：US18931571
申请日：1971-10-14
申请人： UNIV TEMPLE
发明人： LABES M
IPC分类号： C09K19/22 , C07C131/00 , G02F1/28
CPC分类号： C09K19/22
摘要： Stable anil-type nematic liquid crystals are provided of the formula

WHEREIN R1 and R2 are each an alkyl, alkoxy, alkylester, aryl, aryloxy, arylester, aralkyl, carboxylic acid, halogen, nitro, cyano group or the like. The liquid crystals of this invention, because of the excellent stability, are especially useful in light valves, optical display devices and similar applications which involve the modulation of light.
摘要翻译：由式WHEREIN R1和R2各自为烷基，烷氧基，烷基酯，芳基，芳氧基，芳基酯，芳烷基，羧酸，卤素，硝基，氰基等提供稳定的苯胺型向列型液晶。由于稳定性优异，本发明的液晶在涉及光调制的光阀，光学显示装置和类似应用中特别有用。

5. 发明授权

US2451772A Solubilization of rutin with methyl glucamine 失效
标题翻译：用甲基葡糖胺溶解芦丁
公开(公告)号：US2451772A
公开(公告)日：1948-10-19
申请号：US71888946
申请日：1946-12-27
申请人： UNIV TEMPLE
发明人： PLUNGIAN MIKHAIL B
IPC分类号： C07H17/07
CPC分类号： C07H17/07

6. 发明授权

US3741198A Radiological diagnostic method 失效
标题翻译：放射诊断方法
公开(公告)号：US3741198A
公开(公告)日：1973-06-26
申请号：US3741198D
申请日：1971-10-12
申请人： UNIV TEMPLE
发明人： BURTON C
IPC分类号： A61B5/06 , A61B6/00 , A61B5/00
CPC分类号： A61B6/481 , A61B5/06 , A61B6/506
摘要： A radiological diagnostic method is provided in which a radiopaque ferrofluid is injected into a body system which is to be studied, such as the subarachnoid space surrounding the spinal cord. The ferrofluid is then transferred through the body system by applying a magnetic force to the ferrofluid. The portions of the body system of particular interest are radiographicly or fluoroscopicly examined while the ferrofluid is present in these areas. The ferrofluid is thereafter removed by drawing it back to the point of introduction and removing it from the body system. The diagnostic method of this invention is especially useful in myelographic studies.

7. 发明授权

US3681363A Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones 失效
标题翻译： SPIRO（咪唑啉-4,3 {40-奎宁）-2,5-二酮
公开(公告)号：US3681363A
公开(公告)日：1972-08-01
申请号：US3681363D
申请日：1970-08-20
申请人： UNIV TEMPLE
发明人： ELKIN SAMUEL , LIEBERMAN HILLEL
IPC分类号： C07D471/20 , C07D39/06
CPC分类号： C07D471/20
摘要： Spiro(imidazolidine-4,3''-quinuclidine)-2,5-dione and the 1methyl homolog thereof have been prepared and found useful as anti-convulsant agents.
摘要翻译：已经制备了螺（咪唑烷-4,3'-奎宁环）-2,5-二酮及其1-甲基同系物，可用作抗惊厥剂。

8. 发明授权

US3674645A Keratinolytic enzyme isolated from trichophyton mentagorphytes and process therefor 失效
标题翻译：三叉三烯分离的胆碱酯酶及其过程
公开(公告)号：US3674645A
公开(公告)日：1972-07-04
申请号：US3674645D
申请日：1969-08-14
申请人： UNIV TEMPLE
发明人： BLANK FRITZ , DAY WILLIAM C , HARMON SANDRA R , TONCIC PAULINE F , YU RUEY J
IPC分类号： C12N9/58 , C12D13/10
CPC分类号： C12N9/58 , Y10S435/815 , Y10S435/911
摘要： Keratinase is produced by incubating T. Mentagrophytes for several days in growth medium, at a pH of 6-9, containing animal hair, magnesium salt, thiamine, pyridoxine and inositol. Preferably, glucose is also included and the pH is about 7.8. This keratinase is separated by filtering the growth media, partially purifying the enzyme by contact with diethylaminoethyl cellulose and adsorbing the keratinase on carboxymethyl cellulose. The crude keratinase is eluted from the cellulose and purified by molecular sieves, ion exchange resins or other means.
摘要翻译：通过在含有动物毛发，镁盐，硫胺素，吡哆醇和肌醇的6-9的生长培养基中温育T.Mentagrophytes数日来产生角质酶。优选地，还包括葡萄糖，并且pH为约7.8。通过过滤生长培养基分离角蛋白酶，通过与二乙基氨基乙基纤维素接触部分纯化酶并将角蛋白酶吸附在羧甲基纤维素上。粗品角蛋白酶从纤维素中洗脱并通过分子筛，离子交换树脂或其他方法进行纯化。

9. 发明授权

US3607659A Fermentation apparatus 失效
公开(公告)号：US3607659A
公开(公告)日：1971-09-21
申请号：US3607659D
申请日：1968-12-24
申请人： UNIV TEMPLE
发明人： BLOOMER JAMES L
IPC分类号： C12M1/24 , C12B1/00
CPC分类号： C12M23/08 , C12M23/38 , C12M27/02 , C12M37/02
摘要： Apparatus is provided in the form of fermentation vessels which are provided with caps for substantially sealing the same against contamination, and with tube means for communicating between the inside and outside of the vessels. Stirring is effected by a magnetic element disposed within the vessels which is actuated by an external electromagnetic source.

10. 发明授权

US3726877A Amine substituted methylene quinuclidone anti-bacterial agents 失效
标题翻译：胺取代的甲基喹诺酮抗菌剂
公开(公告)号：US3726877A
公开(公告)日：1973-04-10
申请号：US3726877D
申请日：1970-10-28
申请人： UNIV TEMPLE
发明人： ELKIN S , LIEBERMAN H
IPC分类号： C07D453/02 , C07D39/06
CPC分类号： C07D453/02
摘要： A WIDE VARIETY OF SECONDARY AND TETRIARY AMINE-SUBSTITUTED 2-METHYLENE-3-QUINUCLIDONES CONSTITUTE A NEW CLASS OF COMPOUNDS WHICH ARE USEFUL AS ANTI-BACTERIAL AGENTS.

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