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1. 发明授权

US5998445A Pyridine derivatives having anti-ulcerative activity 失效
标题翻译：具有抗溃疡活性的吡啶衍生物
公开(公告)号：US5998445A
公开(公告)日：1999-12-07
申请号：US679473
申请日：1996-07-09
申请人： Shigeru Souda , Norihiro Ueda , Shuhei Miyazawa , Katsuya Tagami , Seiichiro Nomoto , Makoto Okita , Naoyuki Shimomura , Toshihiko Kaneko , Masatoshi Fujimoto , Manabu Murakami , Kiyoshi Oketani , Hideaki Fujisaki , Hisashi Shibata , Tsuneo Wakabayashi
发明人： Shigeru Souda , Norihiro Ueda , Shuhei Miyazawa , Katsuya Tagami , Seiichiro Nomoto , Makoto Okita , Naoyuki Shimomura , Toshihiko Kaneko , Masatoshi Fujimoto , Manabu Murakami , Kiyoshi Oketani , Hideaki Fujisaki , Hisashi Shibata , Tsuneo Wakabayashi
IPC分类号： A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/54 , A61P1/04 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
CPC分类号： C07D401/12 , C07D401/14 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are described.
摘要翻译：描述了可用于预防或治疗消化性溃疡的吡啶衍生物，药物制剂和治疗消化性溃疡的方法。

2. 发明授权

US5798805A Projection type display apparatus 失效
标题翻译：投影式显示装置
公开(公告)号：US5798805A
公开(公告)日：1998-08-25
申请号：US580087
申请日：1995-12-20
申请人： Yoshiharu Ooi , Tsuneo Wakabayashi
发明人： Yoshiharu Ooi , Tsuneo Wakabayashi
IPC分类号： G02F1/13 , G03B21/00 , H04N9/31 , G02F1/1335 , G02F1/137
CPC分类号： H04N9/3111 , H04N9/3152
摘要： A projection type display apparatus has a light source optical system, a first filter (1), a first aperture (17), a condenser lens (13), a liquid crystal element (15) having a color filter for each pixel, a second aperture (18), a second filter (2), a projection optical system which form a schlieren optical system wherein first and second filters each composed of a spectral element for controlling each color of R, G and B are provided.
摘要翻译：投影型显示装置具有光源光学系统，第一滤光器（1），第一孔（17），聚光透镜（13），具有每个像素的滤色器的液晶元件（15），第二孔（18），第二滤光片（2），投影光学系统，其形成均匀光学系统，其中，由用于控制R，G和B的每种颜色的光谱元素组成的第一和第二滤光片。

3. 发明授权

US5708013A Pyridine derivative and therapeutic agent for ulcer comprising the same 失效
标题翻译：吡啶衍生物及其制备的溃疡治疗剂
公开(公告)号：US5708013A
公开(公告)日：1998-01-13
申请号：US524109
申请日：1995-08-21
申请人： Shigeru Souda , Norihiro Ueda , Shuhei Miyazawa , Katsuya Tagami , Seiichiro Nomoto , Makoto Okita , Naoyuki Shimomura , Toshihiko Kaneko , Masatoshi Fujimoto , Manabu Murakami , Kiyoshi Oketani , Hideaki Fujisaki , Hisashi Shibata , Tsuneo Wakabayashi
发明人： Shigeru Souda , Norihiro Ueda , Shuhei Miyazawa , Katsuya Tagami , Seiichiro Nomoto , Makoto Okita , Naoyuki Shimomura , Toshihiko Kaneko , Masatoshi Fujimoto , Manabu Murakami , Kiyoshi Oketani , Hideaki Fujisaki , Hisashi Shibata , Tsuneo Wakabayashi
IPC分类号： C07D401/12 , A61K31/44
CPC分类号： C07D401/12
摘要： A pyridine compound having the formula is disclosed and useful to treat the peptic ulcer. ##STR1## wherein R.sup.1 and R.sup.2 which may be the same or different are each a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogenated lower alkyl group, or a halogen atom, R.sup.3 and R.sup.4 which may be the same or different are each a hydrogen atom or a lower alkyl group, X is a group represented by the formula --S--, a group represented by the formula ##STR2## or a group represented by the formula ##STR3## and n is an integer of 1 to 6, provided that R.sup.3 and R.sup.4 are not simultaneously hydrogen atoms when n is 1.
摘要翻译：公开了具有下式的吡啶化合物，可用于治疗消化性溃疡。其中可以相同或不同的R 1和R 2各自为氢原子，低级烷基，低级烷氧基，卤代低级烷基或卤素原子，可以相同的R 3和R 4，不同的是氢原子或低级烷基，X是由式-S-表示的基团，即由式d表示的基团，当n为1时，R3和R4不同时为氢原子。

4. 发明授权

US5648860A Projection type color liquid crystal optical apparatus 失效
标题翻译：投影型彩色液晶光学装置
公开(公告)号：US5648860A
公开(公告)日：1997-07-15
申请号：US198275
申请日：1994-02-18
申请人： Yoshiharu Ooi , Tsuneo Wakabayashi , Shigeyuki Serizawa , Yoshiyuki Sonda , Masaya Kunigita , Yoshinori Hirai
发明人： Yoshiharu Ooi , Tsuneo Wakabayashi , Shigeyuki Serizawa , Yoshiyuki Sonda , Masaya Kunigita , Yoshinori Hirai
IPC分类号： H04N9/31 , G02F1/1335
CPC分类号： H04N9/315 , H04N9/3105
摘要： A light source optical system for projection 1, dichroic mirrors 21, 22 disposed to have a predetermined included angle .beta., a reflection type liquid crystal optical element blocks 31-33 each including a closely contacted converging lens and having a reflection surface and a projection optical system 4 are provided, wherein the normal line of a dichroic mirror surface and the optical axis of incident light form an included angle .alpha.; the normal line of the reflection surface and the optical axis of incident light form an included angle .gamma.; light emitted from a light source is color-separated so as to become color lights; the color lights are rendered to be parallel light beams, and are modulated and reflected by means of the reflection type liquid crystal optical elements; the reflected light beams are color-synthesized; and the color-synthesized light is projected through a projection lens. A projection type color liquid crystal optical apparatus having a compact shape and a high brightness is obtainable.
摘要翻译：用于突起1的光源光学系统，设置成具有预定夹角β的分色镜21,22，每个包括紧密接合的会聚透镜并具有反射表面的反射型液晶光学元件块31-33和具有反射面的投影光学系统4，其中分色镜表面的法线和入射光的光轴形成夹角α; 反射面的法线和入射光的光轴形成夹角γ; 从光源发出的光被颜色分离，成为色光; 彩色光成为平行光束，通过反射型液晶光学元件进行调制和反射; 反射光束被彩色合成; 并且通过投影透镜投射彩色合成光。可以获得具有紧凑形状和高亮度的投影型彩色液晶光学装置。

5. 发明授权

US5331446A Liquid crystal optical element and a laser projection apparatus using polymer dispersed liquid crystal 失效
标题翻译：液晶光学元件和使用聚合物分散液晶的激光投射装置
公开(公告)号：US5331446A
公开(公告)日：1994-07-19
申请号：US74407
申请日：1993-06-10
申请人： Yoshinori Hirai , Hiroshi Kumai , Takehiko Nishiyama , Satoshi Niiyama , Tsuneo Wakabayashi
发明人： Yoshinori Hirai , Hiroshi Kumai , Takehiko Nishiyama , Satoshi Niiyama , Tsuneo Wakabayashi
IPC分类号： G02F1/1334 , G02F1/137 , G02F1/13 , G02F1/37
CPC分类号： G02F1/1334 , G02F2001/13756
摘要： A laser projection apparatus including a liquid crystal optical element of a transparent and scattering type having a liquid crystal and solidified matrix composite. A laser beam having a wavelength of approximately 1 .mu.m emitted from a laser beam source is supplied to the liquid crystal optical element, and a projection optical system operates for reduction-projection a laser beam emitted from the liquid crystal optical element onto an object. Further, with respect to a certain pixel of the liquid crystal optical element, there are overlapped portions between lead lines of a common electrode and lead lines of a segment electrode in the vicinity of the pixel, a width W.sub.1 (.mu.m) of the overlapped portion, a reduction projection ratio (projection by 1/N) and a gap d(.mu.m) between electrodes of the liquid crystal optical element satisfy the relation, W.sub.1 +d
摘要翻译：一种激光投射装置，包括具有液晶和固化基质复合体的透明散射型液晶光学元件。将从激光源发射的具有约1μm的波长的激光束提供给液晶光学元件，并且投影光学系统用于将从液晶光学元件发射的激光束还原到物体上。此外，对于液晶光学元件的某个像素，在像素附近，公共电极的引线与段电极的引线之间存在重叠的部分，重叠的宽度W1（μm）部分，液晶光学元件的电极之间的缩小投影比（投影1 / N）和间隙d（μm）满足关系式W1 + d <10×N。此外，所用液晶的折射率各向异性DELTA n为0.18以上，粘度eta（cSt）为60以下，折射率平均值DELTA n，平均粒径R（μm）分散并保持在固化基质中的液晶，电极之间的间隙d（μm）满足以下关系：（1）0.5 <ΔTAnxR <1.3，（2）3.5 <ΔDTAnxd <8.0。采用复用驱动来驱动液晶光学元件。

6. 发明授权

US5283675A Liquid crystal display element with electrode having concave-convex surface at liquid crystal side 失效
标题翻译：具有在液晶侧具有凹凸表面的电极的液晶显示元件
公开(公告)号：US5283675A
公开(公告)日：1994-02-01
申请号：US936633
申请日：1992-08-28
申请人： Yoshiharu Ooi , Yoshinori Hirai , Satoshi Niiyama , Tsuneo Wakabayashi
发明人： Yoshiharu Ooi , Yoshinori Hirai , Satoshi Niiyama , Tsuneo Wakabayashi
IPC分类号： G02F1/1333 , G02F1/1334 , G02F1/1335 , G02F1/1343 , G02F1/13
CPC分类号： G02F1/1343 , G02F1/133371 , G02F1/1334 , G02F1/133553 , G02F2001/133397 , G02F2203/30
摘要： A liquid crystal display element comprises a liquid crystal and solidified matrix composite, in which liquid crystal is dispersed and held in a solidified matrix, which is interposed between a pair of substrates with electrodes at least one of which is transparent, wherein at least one of the substrates with electrodes has a fine concave-convex electrode surface at the side for the liquid crystal and solidified matrix composite.
摘要翻译：液晶显示元件包括液晶和固化基质复合物，其中液晶分散并保持在固化的基质中，该固化基质被介于一对基底之间，其中至少一个是透明的电极，其中至少一个是透明的，具有电极的基板在液晶和固化基质复合物的侧面具有微细的凹凸电极表面。

7. 发明授权

US5075335A Guanidinobenzoic ester derivative 失效
标题翻译： GUANIDINOBENZOIC ESTER DERIVATIVE
公开(公告)号：US5075335A
公开(公告)日：1991-12-24
申请号：US495444
申请日：1990-03-16
申请人： Shigeru Souda , Naoyuki Shimomura , Norihiro Ueda , Shuhei Miyazawa , Takashi Yamanaka , Kaname Miyamoto , Ieharu Hishinuma , Junichi Nagakawa , Naoko Nagaoka , Hidetoshi Kawashima , Tsutomu Kawata , Junsaku Nagaoka , Tsuneo Wakabayashi
发明人： Shigeru Souda , Naoyuki Shimomura , Norihiro Ueda , Shuhei Miyazawa , Takashi Yamanaka , Kaname Miyamoto , Ieharu Hishinuma , Junichi Nagakawa , Naoko Nagaoka , Hidetoshi Kawashima , Tsutomu Kawata , Junsaku Nagaoka , Tsuneo Wakabayashi
IPC分类号： A61K31/235 , A61K31/245 , A61K31/40 , A61K31/4015 , A61K31/403 , A61K31/4035 , A61K31/42 , A61K31/421 , A61K31/445 , A61P1/00 , A61P7/02 , A61P7/04 , A61P43/00 , C07C67/00 , C07C313/00 , C07C319/20 , C07C323/20 , C07D207/40 , C07D207/404 , C07D207/408 , C07D209/48 , C07D209/76 , C07D211/76 , C07D211/88 , C07D263/44
CPC分类号： C07D207/404 , C07C323/20 , C07D209/48 , C07D263/44
摘要： A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m --, m being an integer of 2 or 3, ##STR3## or a group of the formula:--ORin which R is a hydrogen atom or a lower alkyl group, and n represents an integer of 1 to 5.

8. 发明授权

US4874869A Hydantoin derivatives and medicines containing the same 失效
标题翻译：乙内酰脲衍生物和含有它们的药物
公开(公告)号：US4874869A
公开(公告)日：1989-10-17
申请号：US73915
申请日：1987-07-13
申请人： Kouichiro Ueda , Satoru Tanaka , Toshinobu Kunii , Kengo Kagei , Tadashi Sato , Hideki Ono , Issei Ohtsuka , Mayumi Kawase , Toshiharu Ohgoh , Tsuneo Wakabayashi
发明人： Kouichiro Ueda , Satoru Tanaka , Toshinobu Kunii , Kengo Kagei , Tadashi Sato , Hideki Ono , Issei Ohtsuka , Mayumi Kawase , Toshiharu Ohgoh , Tsuneo Wakabayashi
IPC分类号： A61K31/415 , A61P3/08 , A61P3/10 , A61P9/10 , A61P25/02 , A61P27/02 , A61P27/12 , C07D233/72 , C07D491/107 , C07D493/10 , C07D495/10
CPC分类号： C07D493/10 , C07D495/10
摘要： Novel hydantoin derivatives and salts thereof, the process for the preparation thereof, and medicines containing the same, wherein the hydantoin derivatives are represented by the general formula: ##STR1## wherein X.sub.1 and X.sub.2, which may be the same or different, mean independently hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; Y means oxygen atom or sulfur atom, R.sub.1 and R.sub.2, which may be the same or different, mean independently hydrogen atom, a lower alkyl group or phenyl group, or the both may form a ring with a carbon atom which is combined with them, excluding the case wherein both R.sub.1 and R.sub.2 are hydrogen atom at the same time, and n means an integer of 0 or 1. The novel hydantoin derivatives and salts thereof have excellent effects for the treatment of the complications of the diabetes mellitus.
摘要翻译：新颖的乙内酰脲衍生物及其盐，其制备方法和含有它们的药物，其中乙内酰脲衍生物由以下通式表示：其中X1和X2可以相同或不同，独立地表示氢原子，卤素原子，低级烷基或低级烷氧基; Y表示氧原子或硫原子，可以相同或不同的R 1和R 2独立地表示氢原子，低级烷基或苯基，或者二者可以与与它们结合的碳原子形成环，不包括R1和R2同时为氢原子的情况，n表示0或1的整数。新的乙内酰脲衍生物及其盐对于治疗糖尿病并发症具有优异的效果。

9. 发明授权

US4801603A Guanidinobenzoic ester derivative 失效
标题翻译：胍基苯甲酸酯衍生物
公开(公告)号：US4801603A
公开(公告)日：1989-01-31
申请号：US946458
申请日：1986-12-24
申请人： Shigeru Souda , Naoyuki Shimomura , Norihiro Ueda , Shuhei Miyazawa , Takashi Yamanaka , Kaname Miyamoto , Ieharu Hishinuma , Junichi Nagakawa , Naoko Nagaoka , Hidetoshi Kawashima , Tsutomu Kawata , Junsaku Nagaoka , Tsuneo Wakabayashi
发明人： Shigeru Souda , Naoyuki Shimomura , Norihiro Ueda , Shuhei Miyazawa , Takashi Yamanaka , Kaname Miyamoto , Ieharu Hishinuma , Junichi Nagakawa , Naoko Nagaoka , Hidetoshi Kawashima , Tsutomu Kawata , Junsaku Nagaoka , Tsuneo Wakabayashi
IPC分类号： A61K31/235 , A61K31/245 , A61K31/40 , A61K31/4015 , A61K31/403 , A61K31/4035 , A61K31/42 , A61K31/421 , A61K31/445 , A61P1/00 , A61P7/02 , A61P7/04 , A61P43/00 , C07C67/00 , C07C313/00 , C07C319/20 , C07C323/20 , C07D207/40 , C07D207/404 , C07D207/408 , C07D209/48 , C07D209/76 , C07D211/76 , C07D211/88 , C07D263/44
CPC分类号： C07D207/404 , C07C323/20 , C07D209/48 , C07D263/44
摘要： A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m --, m being an integer of 2 or 3, ##STR3## or a group of the formula:--ORin which R is a hydrogen atom or a lower alkyl group, and n represents an integer of 1 to 5.
摘要翻译：具有下式的胍基苯甲酸酯衍生物是新颖有效的抑制酶如胰蛋白酶，纤溶酶和凝血酶，可用于治疗胰腺炎和出血性疾病和血栓形成。其中X表示下式的基团：其中Y是下式的基团： - （CH 2）m - ，m是2或3的整数，或基团其中R是氢原子或低级烷基，n表示1〜5的整数。

10. 发明授权

US5844638A Light source apparatus using a cone-shaped element and an applied apparatus thereof 失效
标题翻译：使用锥形元件的光源装置及其施加装置
公开(公告)号：US5844638A
公开(公告)日：1998-12-01
申请号：US781234
申请日：1997-01-10
申请人： Yoshiharu Ooi , Tsuneo Wakabayashi , Shigeyuki Serizawa , Yoshiyuki Sonda
发明人： Yoshiharu Ooi , Tsuneo Wakabayashi , Shigeyuki Serizawa , Yoshiyuki Sonda
IPC分类号： H04N9/31 , G02F1/1335 , G03B21/20
CPC分类号： H04N9/3105 , H04N9/315
摘要： A projection type display apparatus comprising a light source apparatus which is provided with an elliptic mirror 12, a light source 11 disposed at the first focal point, a cone-like material disposed at the second focal point, a condenser lens 13, display elements 15R-15B, a color separating and synthesizing optical system, second condenser lenses 16R-16B and a projection lens 19. The cone-like material is one selected from the group of a convex cone lens, a concave cone lens 2, a convex cone-like reflector and a concave cone-like reflector 20. In the projection type display element, light emitted from the light source is introduced into the cone-like material and is emitted as divergent light through the conical surface of the cone-like material. The divergent light is introduced into the condenser lens 13 so that the light is rendered to be parallel light fluxes, which are color-separated and introduced into the display elements 15R-15B disposed for each color in order to form light fluxes of display colors. The light fluxes are again subjected to color synthesization, and the synthesized light is projected as a full color picture image on a screen through the projection lens 19. The projection type display apparatus provides a display having uniformity, a good contrast ratio and brightness.
摘要翻译：一种投影型显示装置，包括设置有椭圆镜12，设置在第一焦点处的光源11，设置在第二焦点处的锥形材料的光源装置，聚光透镜13，显示元件15R -15B，分色合成光学系统，第二聚光透镜16R-16B和投影透镜19.锥形材料选自凸锥形透镜，凹锥形透镜2，凸锥形透镜，在投影型显示元件中，从光源发射的光被引入到锥形材料中，并作为发散光通过锥形材料的锥形表面发射。发散光被引入到聚光透镜13中，使得光成为平行光束，其被分色并被引入到为每种颜色设置的显示元件15R-15B中，以便形成显示颜色的光通量。光束再次进行颜色合成，并且合成的光通过投影透镜19投影在屏幕上作为全色图像。投影型显示装置提供具有均匀性，良好的对比度和亮度的显示。

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