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1. 发明授权

US08721552B2 Compressive surfaces for ultrasonic scanning 有权
标题翻译：压缩表面用于超声波扫描
公开(公告)号：US08721552B2
公开(公告)日：2014-05-13
申请号：US13489091
申请日：2012-06-05
申请人： Tor C. Anderson , Jiayu Chen , Shih-Ping Wang
发明人： Tor C. Anderson , Jiayu Chen , Shih-Ping Wang
IPC分类号： A61B8/00
CPC分类号： A61B8/0825 , A61B8/406 , A61B8/4218 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/483
摘要： Automated ultrasonic scanning of a chestwardly compressed breast of a supine patient uses a scanning assembly that moves down to compress the breast through a membrane that is secured to the assembly across a bottom opening. A motorized ultrasound transducer moves across the breast while the breast remains downwardly compressed against the patient's chest, sending and receiving ultrasound energy through the membrane. The membrane is porous with respect to an acoustic coupling liquid that impregnates it. The transducer outputs ultrasound information that is processed to form initial planar images and then reconstructed slice images of breast tissue.
摘要翻译：仰卧患者胸部压缩乳房的自动超声波扫描使用向下移动的扫描组件，以通过穿过底部开口固定到组件的膜来压缩乳房。电动超声波换能器穿过乳房，同时乳房保持向下压迫患者的胸部，通过膜发送和接收超声能量。相对于浸渍它的声耦合液体，膜是多孔的。传感器输出被处理以形成初始平面图像，然后重建乳腺组织切片图像的超声信息。

2. 发明申请

US20100256500A1 Compressive Surfaces For Ultrasonic Tissue Scanning 有权
标题翻译：用于超声波组织扫描的压缩表面
公开(公告)号：US20100256500A1
公开(公告)日：2010-10-07
申请号：US12769440
申请日：2010-04-28
申请人： Tor C. Anderson , Jiaya Chen , Shih-Ping Wang
发明人： Tor C. Anderson , Jiaya Chen , Shih-Ping Wang
IPC分类号： A61B8/14
CPC分类号： A61B8/0825 , A61B8/406 , A61B8/4218 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/483
摘要： Automated ultrasonic scanning of a chestwardly compressed breast of a supine patient uses a scanning assembly that moves down to compress the breast through a membrane that is secured to the assembly across a bottom opening. A motorized ultrasound transducer moves across the breast while the breast remains downwardly compressed against the patient's chest, sending and receiving ultrasound energy through the membrane. The membrane is porous with respect to an acoustic coupling liquid that impregnates it. The transducer outputs ultrasound information that is processed to form initial planar images and then reconstructed slice images of breast tissue.
摘要翻译：仰卧患者胸部压缩乳房的自动超声波扫描使用向下移动的扫描组件，以通过穿过底部开口固定到组件的膜来压缩乳房。电动超声波换能器穿过乳房，同时乳房保持向下压迫患者的胸部，通过膜发送和接收超声能量。相对于浸渍它的声耦合液体，膜是多孔的。传感器输出被处理以形成初始平面图像，然后重建乳腺组织切片图像的超声信息。

3. 发明申请

US20100174185A1 ULTRASOUND SCANNING AND ULTRASOUND-ASSISTED BIOPSY 审中-公开
标题翻译：超声波扫描和超声波辅助生物
公开(公告)号：US20100174185A1
公开(公告)日：2010-07-08
申请号：US12299275
申请日：2007-05-02
申请人： Shih-Ping Wang , Tor C. Anderson , Jiayu Chen , Douglas G. Summers
发明人： Shih-Ping Wang , Tor C. Anderson , Jiayu Chen , Douglas G. Summers
IPC分类号： A61B8/00 , A61B10/02
CPC分类号： A61B8/0825 , A61B8/0833 , A61B8/0841 , A61B8/14 , A61B8/4218 , A61B8/4455 , A61B8/4461 , A61B8/4472 , A61B8/4483 , A61B8/54 , G01S15/8934
摘要： An apparatus and related methods for ultrasonically scanning a tissue sample are described, the apparatus comprising an ultrasound transducer and a membranous sheet, the membranous sheet compressing the tissue sample, the ultrasound transducer contacting the membranous sheet and ultrasonically scanning the tissue sample therethrough, wherein the membranous sheet has a generally arcuate shape and the ultrasound transducer is movable in a generally arcuate trajectory therealong during the ultrasonic scan. Also described is an apparatus for facilitating a medical procedure, comprising a membranous sheet compressing a tissue sample, an ultrasound transducer contacting the membranous sheet to ultrasonically scan the tissue sample therethrough, and a biopsy guide operably coupled to the ultrasound transducer for maintaining a biopsy instrument in a scan plane of the ultrasound transducer to facilitate a percutaneous biopsy of a lesion located in the scan plane.
摘要翻译：描述了用于超声波扫描组织样品的装置和相关方法，所述装置包括超声换能器和膜片，所述膜片压缩所述组织样本，所述超声波换能器接触所述膜片并且超声扫描所述组织样本，其中，膜片具有大致弓形的形状，并且超声波换能器在超声波扫描期间沿着大致弧形的轨迹移动。还描述了一种用于促进医疗过程的装置，包括压缩组织样本的膜片，接触膜片的超声波换能器以超声扫描组织样本，以及可操作地耦合到超声换能器的活检导管，用于维持活检器械在超声换能器的扫描平面中，以便于位于扫描平面中的病变的经皮活检。

4. 发明申请

US20070282221A1 ULTRASOUND ASSISTED AND X-RAY ASSISTED BIOPSY DEVICES 审中-公开
标题翻译：超声辅助和X射线辅助生物设备
公开(公告)号：US20070282221A1
公开(公告)日：2007-12-06
申请号：US11757996
申请日：2007-06-04
申请人： Shih-Ping WANG , Tor C. Anderson
发明人： Shih-Ping WANG , Tor C. Anderson
IPC分类号： A61B10/00
CPC分类号： A61B10/0233 , A61B90/11 , A61B2090/376 , A61B2090/378
摘要： Improved systems and related methods for x-ray assisted breast biopsy and ultrasound-assisted breast biopsy are described. In one preferred embodiment, for example, an apparatus for facilitating both x-ray assisted and ultrasound assisted breast biopsy is provided, comprising a biopsy table for supporting a patient in a prone position between first and second opposing ends thereof, the biopsy table having first and second openings, respectively, toward each of the first and second ends, through which the patient's breast may project depending on the patient's orientation on the biopsy table. The apparatus further comprises an ultrasound-assisted biopsy system positioned beneath the first opening, and an x-ray-assisted biopsy system positioned beneath the second opening. In other preferred embodiments, the ultrasound-assisted biopsy system and x-ray assisted biopsy system are mechanically interchangeable beneath a single opening. In other preferred embodiments, novel integrations between specified components of the ultrasound-assisted and x-ray-assisted biopsy systems are provided.
摘要翻译：描述了改进的x射线辅助乳腺活检和超声辅助乳腺活检的系统和相关方法。在一个优选实施例中，例如，提供了一种用于促进X射线辅助和超声辅助乳腺活检的装置，其包括用于在第一和第二相对端之间的俯卧位置支撑患者的活检台，所述活检台具有第一和第二开口，分别朝向第一和第二端部中的每一个，患者的乳房可以根据患者在活检台上的取向投射。该装置还包括位于第一开口下方的超声辅助活检系统和位于第二开口下方的x射线辅助活检系统。在其它优选实施例中，超声辅助活检系统和x射线辅助活检系统在单个开口下方可机械互换。在其它优选实施例中，提供了超声辅助和X射线辅助活检系统的特定部件之间的新颖的整合。

5. 发明授权

US5777325A Device for time lag focusing time-of-flight mass spectrometry 失效
标题翻译：时差聚焦飞行时间质谱仪的设备
公开(公告)号：US5777325A
公开(公告)日：1998-07-07
申请号：US643708
申请日：1996-05-06
申请人： Scot R. Weinberger , Edward P. Donlon , Yevgeny Kaplun , Tor C. Anderson , Liang Li , Larry Russon , Randy Whittal
发明人： Scot R. Weinberger , Edward P. Donlon , Yevgeny Kaplun , Tor C. Anderson , Liang Li , Larry Russon , Randy Whittal
IPC分类号： H01J49/02 , H01J49/40
CPC分类号： H01J49/40 , H01J49/025
摘要： A laser desorption ionization instrument for and method of measuring the molecular weight of large organic molecules includes a time of flight mass spectrometer (TOF MS). The TOF MS instrument provides optimized optic design for both DC and TLF modes. The invention further provides dynamic resolution enhancement for a given ejection pulse, along with optimized ion ejection pulses relative to the ion optic elements. The invention also provides means for compensating for difference in total kinetic energy among ions of different mass; high resolution detection means for improved sensitivity for large molecular weight species. The invention further provides x-y-z stage for sample presentation of both standard MALDI and gel or membrane based samples.
摘要翻译：用于测量大型有机分子分子量的激光解吸电离仪及其测定方法包括飞行时间质谱仪（TOF MS）。 TOF MS仪器为DC和TLF模式提供优化的光学设计。本发明还提供了对于给定的喷射脉冲的动态分辨率增强以及相对于离子光学元件的优化的离子喷射脉冲。本发明还提供了补偿不同质量离子之间总动能差异的方法; 高分辨率检测手段，用于提高大分子量物种的灵敏度。本发明还提供用于标准MALDI和基于凝胶或膜的样品的样品呈现的x-y-z级。

6. 发明授权

US08241219B2 Compressive surfaces for ultrasonic tissue scanning 有权
标题翻译：用于超声波组织扫描的压缩表面
公开(公告)号：US08241219B2
公开(公告)日：2012-08-14
申请号：US12769440
申请日：2010-04-28
申请人： Tor C. Anderson , Jiaya Chen , Shih-Ping Wang
发明人： Tor C. Anderson , Jiaya Chen , Shih-Ping Wang
IPC分类号： A61B8/00
CPC分类号： A61B8/0825 , A61B8/406 , A61B8/4218 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/483
摘要： Automated ultrasonic scanning of a chestwardly compressed breast of a supine patient uses a scanning assembly that moves down to compress the breast through a membrane that is secured to the assembly across a bottom opening. A motorized ultrasound transducer moves across the breast while the breast remains downwardly compressed against the patient's chest, sending and receiving ultrasound energy through the membrane. The membrane is porous with respect to an acoustic coupling liquid that impregnates it. The transducer outputs ultrasound information that is processed to form initial planar images and then reconstructed slice images of breast tissue.
摘要翻译：仰卧患者胸部压缩乳房的自动超声波扫描使用向下移动的扫描组件，以通过穿过底部开口固定到组件的膜来压缩乳房。电动超声波换能器穿过乳房，同时乳房保持向下压迫患者的胸部，通过膜发送和接收超声能量。相对于浸渍它的声耦合液体，膜是多孔的。传感器输出被处理以形成初始平面图像，然后重建乳腺组织切片图像的超声信息。

7. 发明申请

US20100076311A1 THICK-SLICE PROCESSING AND DISPLAY OF INFORMATION FROM A VOLUMETRIC ULTRASOUND SCAN OF A CHESTWARDLY COMPRESSED BREAST 审中-公开
标题翻译：厚片加工和信息显示从一个西门子压缩乳头的体积超声波扫描
公开(公告)号：US20100076311A1
公开(公告)日：2010-03-25
申请号：US12441975
申请日：2007-09-21
申请人： Laszlo Tabar , Shih-Ping Wang , Tor C. Anderson , Jiayu Chen
发明人： Laszlo Tabar , Shih-Ping Wang , Tor C. Anderson , Jiayu Chen
IPC分类号： A61B8/14 , G06K9/00
CPC分类号： A61B8/0825 , A61B8/523
摘要： Systems, methods, and related computer program products for acquiring, processing, and displaying breast ultrasound information are described. In one preferred embodiment, a three-dimensional data volume of a sonographic property of a chestwardly compressed breast is acquired, and the data volume is processed to generate a plurality of two-dimensional coronal thick-slice images. Each coronal thick-slice image is representative of the sonographic property within a thick-slice subvolume of the breast substantially parallel to a coronal plane. The thick-slice subvolume has a thickness selected for optimal viewing of terminal ductal lobular unit (TDLU) patterns in a display of the thick-slice images.
摘要翻译：描述了用于获取，处理和显示乳房超声信息的系统，方法和相关的计算机程序产品。在一个优选实施例中，获取胸部压缩乳房的超声波特性的三维数据体积，并处理数据体积以产生多个二维冠状厚片图像。每个冠状厚片图像代表基本上平行于冠状面的乳房的厚切片子体积内的超声波特性。厚片子体积具有选择用于在厚片图像的显示器中最佳观看末端导管小叶单元（TDLU）图案的厚度。

8. 发明申请

US20120130241A1 HANDHELD VOLUMETRIC ULTRASOUND SCANNING DEVICE 审中-公开
标题翻译：手持式体积超声波扫描装置
公开(公告)号：US20120130241A1
公开(公告)日：2012-05-24
申请号：US13361065
申请日：2012-01-30
申请人： Shih-Ping WANG , Douglas G. SUMMERS , Jiavu CHEN , Tor C. ANDERSON
发明人： Shih-Ping WANG , Douglas G. SUMMERS , Jiavu CHEN , Tor C. ANDERSON
IPC分类号： A61B8/13 , A61N5/00 , A61B8/00
CPC分类号： A61B10/0233 , A61B8/4427 , A61B8/4455 , A61B8/4461 , A61B8/483 , A61B90/11 , A61B2090/378
摘要： An apparatus and related methods for ultrasonically scanning a tissue volume are described, the apparatus being particularly advantageous in the context of freehand ultrasound assisted biopsy of the breast although readily applied to non-biopsy contexts and other body parts. The apparatus comprises a casing configured and dimensioned for single-handed manipulation relative to a surface of the tissue, and a texturably couplant-porous material sheet extending across an opening of the casing. The texturably couplant-porous material sheet has an outer side and an inner side relative to the casing, the outer side for compressively contacting the tissue surface. The apparatus further comprises an ultrasound transducer positioned against the inner side of the texturably couplant-porous material sheet and being mechanically translatable thereacross for volumetrically scanning the tissue volume therethrough.
摘要翻译：描述了用于超声扫描组织体积的装置和相关方法，该装置在乳房的手写超声辅助活检的上下文中特别有利，尽管容易地应用于非活检上下文和其他身体部位。该装置包括一个外壳，其被配置和尺寸设计成相对于该组织的表面进行单手操作，以及一个横跨该外壳的开口延伸的可变形的耦合剂 - 多孔材料片。可变形的联合多孔材料片具有相对于外壳的外侧和内侧，用于压缩地接触组织表面的外侧。该装置还包括一个超声波换能器，该超声波换能器抵靠着可柔软的耦合剂 - 多孔材料片的内侧，并可在其上机械平移，用于体积扫描组织体积。

9. 发明授权

US08128568B2 Handheld volumetric ultrasound scanning device 有权
标题翻译：手持式体积超声波扫描装置
公开(公告)号：US08128568B2
公开(公告)日：2012-03-06
申请号：US12238091
申请日：2008-09-25
申请人： Shih-Ping Wang , Douglas G. Summers , Jiayu Chen , Tor C. Anderson
发明人： Shih-Ping Wang , Douglas G. Summers , Jiayu Chen , Tor C. Anderson
IPC分类号： A61B8/00
CPC分类号： A61B10/0233 , A61B8/4427 , A61B8/4455 , A61B8/4461 , A61B8/483 , A61B90/11 , A61B2090/378
摘要： An apparatus and related methods for ultrasonically scanning a tissue volume are described, the apparatus being particularly advantageous in the context of freehand ultrasound assisted biopsy of the breast although readily applied to non-biopsy contexts and other body parts. The apparatus comprises a casing configured and dimensioned for single-handed manipulation relative to a surface of the tissue, and a texturably couplant-porous material sheet extending across an opening of the casing. The texturably couplant-porous material sheet has an outer side and an inner side relative to the casing, the outer side for compressively contacting the tissue surface. The apparatus further comprises an ultrasound transducer positioned against the inner side of the texturably couplant-porous material sheet and being mechanically translatable thereacross for volumetrically scanning the tissue volume therethrough.
摘要翻译：描述了用于超声扫描组织体积的装置和相关方法，该装置在乳房的手写超声辅助活检的上下文中特别有利，尽管容易地应用于非活检上下文和其他身体部位。该装置包括一个外壳，其被配置和尺寸设计成相对于该组织的表面进行单手操作，以及一个横跨该外壳的开口延伸的可变形的耦合剂 - 多孔材料片。可变形的联合多孔材料片具有相对于外壳的外侧和内侧，用于压缩地接触组织表面的外侧。该装置还包括一个超声波换能器，该超声波换能器抵靠着可柔软的耦合剂 - 多孔材料片的内侧，并可在其上机械平移，用于体积扫描组织体积。

10. 发明申请

US20090024039A1 HANDHELD VOLUMETRIC ULTRASOUND SCANNING DEVICE 有权
标题翻译：手持式体积超声波扫描装置
公开(公告)号：US20090024039A1
公开(公告)日：2009-01-22
申请号：US12238091
申请日：2008-09-25
申请人： Shih-Ping WANG , Douglas G. Summers , Jiayu Chen , Tor C. Anderson
发明人： Shih-Ping WANG , Douglas G. Summers , Jiayu Chen , Tor C. Anderson
IPC分类号： A61B8/14
CPC分类号： A61B10/0233 , A61B8/4427 , A61B8/4455 , A61B8/4461 , A61B8/483 , A61B90/11 , A61B2090/378
摘要： An apparatus and related methods for ultrasonically scanning a tissue volume are described, the apparatus being particularly advantageous in the context of freehand ultrasound assisted biopsy of the breast although readily applied to non-biopsy contexts and other body parts. The apparatus comprises a casing configured and dimensioned for single-handed manipulation relative to a surface of the tissue, and a texturably couplant-porous material sheet extending across an opening of the casing. The texturably couplant-porous material sheet has an outer side and an inner side relative to the casing, the outer side for compressively contacting the tissue surface. The apparatus further comprises an ultrasound transducer positioned against the inner side of the texturably couplant-porous material sheet and being mechanically translatable thereacross for volumetrically scanning the tissue volume therethrough.
摘要翻译：描述了用于超声扫描组织体积的装置和相关方法，该装置在乳房的手写超声辅助活检的上下文中特别有利，尽管容易地应用于非活检上下文和其他身体部位。该装置包括一个外壳，其被配置和尺寸设计成相对于该组织的表面进行单手操作，以及一个横跨该外壳的开口延伸的可变形的耦合剂 - 多孔材料片。可变形的联合多孔材料片具有相对于外壳的外侧和内侧，用于压缩地接触组织表面的外侧。该装置还包括一个超声波换能器，该超声波换能器抵靠着可柔软的耦合剂 - 多孔材料片的内侧，并可在其上机械平移，用于体积扫描组织体积。

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