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1. 发明授权

US08900385B2 Composite for on demand fragrance delivery and related method of manufacture 有权
标题翻译：复合用于按需香料送货及相关制造方法
公开(公告)号：US08900385B2
公开(公告)日：2014-12-02
申请号：US13022603
申请日：2011-02-07
申请人： Christopher Gough , Margaret Hyde , Timothy Thomson
发明人： Christopher Gough , Margaret Hyde , Timothy Thomson
IPC分类号： A62B7/08 , B29C65/48 , A61L9/04 , B32B3/28 , B32B3/08 , A45D40/00 , B32B37/20 , C09J7/02 , B32B7/12 , B32B5/18 , A45D37/00 , B32B38/00 , B32B27/40 , B32B27/36 , B32B3/04 , B32B27/32 , B32B3/26 , C11D3/50 , B32B29/00 , B32B27/10 , B32B27/06 , B29C65/00 , B29C51/10 , B32B37/24
CPC分类号： B32B37/206 , A45D37/00 , A45D40/0087 , A61L9/042 , B29C51/10 , B29C66/112 , B29C66/131 , B29C66/53461 , B29C2791/001 , B29C2791/006 , B29C2793/009 , B32B3/04 , B32B3/085 , B32B3/266 , B32B3/28 , B32B5/18 , B32B7/06 , B32B7/12 , B32B27/065 , B32B27/08 , B32B27/10 , B32B27/283 , B32B27/32 , B32B27/36 , B32B27/40 , B32B29/002 , B32B29/007 , B32B38/0004 , B32B2037/243 , B32B2250/03 , B32B2255/10 , B32B2255/12 , B32B2255/26 , B32B2260/02 , B32B2260/04 , B32B2266/025 , B32B2266/0278 , B32B2266/06 , B32B2305/022 , B32B2307/726 , B32B2307/732 , B32B2309/105 , B32B2405/00 , C09J7/29 , C09J2201/20 , C09J2400/226 , C09J2400/243 , C09J2423/00 , C09J2423/006 , C09J2467/00 , C09J2467/006 , C09J2475/00 , C09J2475/006 , C09J2483/005 , C11D3/505 , Y10T156/10
摘要： A composite for on demand release of fragrance, comprising a foam layer imbibed with fragrance; a top polymer layer, impermeable to said fragrance but containing perforations; and a bottom double sided film adhesive layer with a releaser liner on the outside surface; such that said foam layer is in between said top and bottom layer and when compressed by a user said fragrance is released thru the perforations in said top layer. Related method of manufacture and use of the composites in a book are also provided.
摘要翻译：一种用于按需释放香料的复合材料，包括吸收香料的泡沫层; 顶部聚合物层，不透气的所述香料，但包含穿孔; 和在外表面上具有释放衬垫的底部双面胶粘剂层; 使得所述泡沫层位于所述顶层和底层之间，并且当被使用者压缩时，所述香料通过所述顶层中的穿孔被释放。还提供了相关的制造和使用复合材料在书中的方法。

2. 发明申请

US20080203031A1 Foam Composite for Absorption of Hydrocarbon and Process for Making Same 审中-公开
标题翻译：用于吸收烃的泡沫复合材料及其制造方法
公开(公告)号：US20080203031A1
公开(公告)日：2008-08-28
申请号：US10588364
申请日：2005-02-03
申请人： Timothy Thomson
发明人： Timothy Thomson
IPC分类号： C02F1/58 , B32B3/26 , B29C44/00
CPC分类号： C08J9/405 , C02F1/285 , C02F1/681 , C08J2205/05 , C08J2375/04 , C08J2475/00 , Y10T428/249953
摘要： A foam composite adapted to remove sparingly soluble hydrocarbon contaminants from water is provided. The adapted foam composite comprises a scaffold of an open cell hydrophobic polyurethane foam having a plurality of pores with a plurality of surfaces which have a coating of hydrophobic polyurethane disposed thereupon. The foam composite may be made by preparing a hydrophobic polyurethane prepolymer comprising the reaction product of a C8-C12 monohydric alcohol with a polyisocyanate, contacting an open cell hydrophobic polyurethane foam having a plurality of pores having a plurality of surfaces with the hydrophobic polyurethanes prepolymer and a polyol, and curing the prepolymer to form a coating of hydrophobic polyurethane on the surfaces of the pores of the hydrophobic polyurethane foam.
摘要翻译：提供适于从水中除去微溶烃的污染物的泡沫复合材料。改性的泡沫复合材料包括开孔疏水性聚氨酯泡沫的支架，其具有多个具有多个表面的孔，所述多个表面具有设置在其上的疏水性聚氨酯涂层。泡沫复合材料可以通过制备包含C8-C12一元醇与多异氰酸酯的反应产物的疏水性聚氨酯预聚物来制备，所述反应产物与具有多个表面的多个孔与疏水性聚氨酯预聚物接触，多元醇，并固化预聚物以在疏水性聚氨酯泡沫的孔的表面上形成疏水性聚氨酯涂层。

3. 发明申请

US20060216492A1 Foam Composite 审中-公开
标题翻译：泡沫复合材料
公开(公告)号：US20060216492A1
公开(公告)日：2006-09-28
申请号：US11277103
申请日：2006-03-21
申请人： Timothy Thomson
发明人： Timothy Thomson
IPC分类号： B32B3/26
CPC分类号： C08J9/405 , B32B5/18 , C08J9/0009 , C08J9/365 , C08J9/42 , C08J2205/05 , C08J2375/04 , C08J2475/00 , Y10T428/249953 , Y10T428/249954 , Y10T428/249955 , Y10T428/249958 , Y10T428/24996 , Y10T428/249978 , Y10T428/249979 , Y10T428/249981 , Y10T428/249986 , Y10T428/249991
摘要： A foam composite made up of a scaffold of an open cell hydrophobic material having plurality of surfaces defining a plurality of pores, and a coating of a substantially hydrophilic foam material disposed upon the surfaces of the hydrophobic foam. The resulting foam composite exhibits structural characteristics of the hydrophobic foam and absorbency characteristics of the hydrophilic foam.
摘要翻译：由具有限定多个孔的多个表面的开孔细胞疏水材料的支架构成的泡沫复合材料和设置在疏水性泡沫表面上的基本上亲水的泡沫材料的涂层。所得泡沫复合材料表现出疏水性泡沫的结构特征和亲水性泡沫的吸收特性。

4. 发明授权

US4541965A Dispersants for aqueous slurries 失效
标题翻译：水性浆液分散剂
公开(公告)号：US4541965A
公开(公告)日：1985-09-17
申请号：US642988
申请日：1984-08-22
申请人： Timothy Thomson , Ronald L. Glomski
发明人： Timothy Thomson , Ronald L. Glomski
IPC分类号： B01F17/00 , B01F17/12 , C10L1/32 , C07C143/24
CPC分类号： B01F17/0057
摘要： The present invention provides a water-soluble dispersant for aqueous slurries of coal, lignite, cement, gypsum, and fillers. The dispersant comprises a sulfonated mixture of polynuclear fused-ring aromatic hydrocarbon compounds. The mixture, prior to sulfonation, (a) is liquid at a temperature of 100.degree. Centigrade, (b) has an aromatic content of more than about sixty percent, (c) a molecular weight distribution of from about 150 to about 10,000, and (d) a weight average molecular weight of less than about five hundred.
摘要翻译：本发明提供了用于煤，褐煤，水泥，石膏和填料的水性浆料的水溶性分散剂。分散剂包括多核稠环芳烃化合物的磺化混合物。磺化前的混合物（a）在100℃的温度下为液体，（b）芳族含量大于约百分之六十，（c）约150至约10,000的分子量分布，以及（d）重均分子量小于约500。

5. 发明申请

US20110194983A1 COMPOSITE FOR ON DEMAND FRAGRANCE DELIVERY AND RELATED METHOD OF MANUFACTURE 有权
标题翻译：复合材料用于需求交付和相关制造方法
公开(公告)号：US20110194983A1
公开(公告)日：2011-08-11
申请号：US13022603
申请日：2011-02-07
申请人： Christopher GOUGH , Margaret Hyde , Timothy Thomson
发明人： Christopher GOUGH , Margaret Hyde , Timothy Thomson
IPC分类号： A62B7/08 , B29C65/48
CPC分类号： B32B37/206 , A45D37/00 , A45D40/0087 , A61L9/042 , B29C51/10 , B29C66/112 , B29C66/131 , B29C66/53461 , B29C2791/001 , B29C2791/006 , B29C2793/009 , B32B3/04 , B32B3/085 , B32B3/266 , B32B3/28 , B32B5/18 , B32B7/06 , B32B7/12 , B32B27/065 , B32B27/08 , B32B27/10 , B32B27/283 , B32B27/32 , B32B27/36 , B32B27/40 , B32B29/002 , B32B29/007 , B32B38/0004 , B32B2037/243 , B32B2250/03 , B32B2255/10 , B32B2255/12 , B32B2255/26 , B32B2260/02 , B32B2260/04 , B32B2266/025 , B32B2266/0278 , B32B2266/06 , B32B2305/022 , B32B2307/726 , B32B2307/732 , B32B2309/105 , B32B2405/00 , C09J7/29 , C09J2201/20 , C09J2400/226 , C09J2400/243 , C09J2423/00 , C09J2423/006 , C09J2467/00 , C09J2467/006 , C09J2475/00 , C09J2475/006 , C09J2483/005 , C11D3/505 , Y10T156/10
摘要： A composite for on demand release of fragrance, comprising a foam layer imbibed with fragrance; a top polymer layer, impermeable to said fragrance but containing perforations; and a bottom double sided film adhesive layer with a releaser liner on the outside surface; such that said foam layer is in between said top and bottom layer and when compressed by a user said fragrance is released thru the perforations in said top layer. Related method of manufacture and use of the composites in a book are also provided.
摘要翻译：一种用于按需释放香料的复合材料，包括吸收香料的泡沫层; 顶部聚合物层，不透气的所述香料，但包含穿孔; 和在外表面上具有释放衬垫的底部双面胶粘剂层; 使得所述泡沫层位于所述顶层和底层之间，并且当被使用者压缩时，所述香料通过所述顶层中的穿孔被释放。还提供了相关的制造和使用复合材料在书中的方法。

6. 发明申请

US20110160189A1 COMPOUND THAT CAN INHIBIT UBC13-UEV INTERACTIONS, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC USES 失效
标题翻译：可抑制UBC13-UEV相互作用，药物组合物和治疗用途的化合物
公开(公告)号：US20110160189A1
公开(公告)日：2011-06-30
申请号：US12309429
申请日：2007-03-07
申请人： Timothy Thomson Okatsu , Johanna Scheper Sigmund , Angel Messeguer Peypoch , Ángel Ramírez Ortiz , María Luz Ortiz Melguizo , Ma Carmen Fabrega Claveria , Gloria Sanclimens Pérez de Rozas , Isabel Masip Masip , Alejandra Moure Fernández , Domingo González Ruiz , Antonio Morreale de León
发明人： Timothy Thomson Okatsu , Johanna Scheper Sigmund , Angel Messeguer Peypoch , Ángel Ramírez Ortiz , María Luz Ortiz Melguizo , Ma Carmen Fabrega Claveria , Gloria Sanclimens Pérez de Rozas , Isabel Masip Masip , Alejandra Moure Fernández , Domingo González Ruiz , Antonio Morreale de León
IPC分类号： A61K31/551 , C07D243/08 , C07D401/02 , A61K31/496 , A61P35/00
CPC分类号： C07D401/12 , C07D241/08 , C07D243/08
摘要： The invention relates to a compound (I) wherein R is a heterocyclyl radical; R1 and R2 are independently H or alkyl; R3 is H, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, aryl, arylalkyl, heterocyclyl or heterocyclylalkyl; R4 and R5 are independently H or alkyl; q is a number selected from 0 and 1; and the salts, solvates, prodrugs or stereoisomers thereof having inhibitory activity for UBC13-UEV interactions and which can be used in the production of pharmaceutical compositions intended for antitumor therapy or the treatment and/or prophylaxis of diseases associated to metabolic pathways involving the UBC13 enzyme, metabolic pathways involving transcriptional factor NF-κB, or pathways involving PCNA or RAD6. R—(CR1R2)q-CO—N(R3)—C(R4R5)—CO—NH2 (I)
摘要翻译：本发明涉及其中R是杂环基的化合物（I）; R1和R2独立地为H或烷基; R3是H，烷基，环烷基，环烷基烷基，烯基，芳基，芳基烷基，杂环基或杂环基烷基; R4和R5独立地是H或烷基; q是选自0和1的数字; 其具有对UBC13-UEV相互作用具有抑制活性的盐，溶剂合物，前体药物或立体异构体，其可用于生产旨在用于抗肿瘤治疗或治疗和/或预防涉及UBC13酶的代谢途径的疾病的药物组合物涉及转录因子NF-κB或涉及PCNA或RAD6的途径的代谢途径。 R-（CR1R2）q-CO-N（R3）-C（R4R5）-CO-NH2（I）

7. 发明授权

US4845206A Production of cellulose ethers using a premix of alkali and etherifying agent 失效
标题翻译：使用碱和醚化剂的预混物生产纤维素醚
公开(公告)号：US4845206A
公开(公告)日：1989-07-04
申请号：US52645
申请日：1987-05-21
申请人： Timothy Thomson , Cindy J. Jones
发明人： Timothy Thomson , Cindy J. Jones
IPC分类号： C08B11/02 , C08B11/00 , C08B11/193
CPC分类号： C08B11/00
摘要： A process for the preparation of a cellulose ether by reacting in a heterogenous reaction mixture an alkaline solution and an etherifying agent with a fibrous cellulose. The total of the required stoichiometric amount of the alkaline solution and at least a portion of the etherifying agent required in producing the cellulose ether are admixed (e.g. in a mixing nozzle) at sufficiently low temperature to suppress reaction between the alkaline solution and the etherifying agent. The admixture is then contacted with the cellulose fibers, preferably by spraying the admixture thereupon. Additional of the etherifying agent if required is then added to the reaction mixture, and the heterogenous reaction mixture is agitated and reacted at an initial temperature below 40.degree. C. sufficient to produce alkalization of the cellulose. Thereafter the temperature is increased above 40.degree. C., preferably incrementally or gradually up to about 100.degree. C., preferably to 80.degree. C., to produce etherification of the cellulose and form the cellulose ether.

8. 发明授权

US08252786B2 Compound that can inhibit UBC13-UEV interactions, pharmaceutical compositions and therapeutic uses 失效
标题翻译：可抑制UBC13-UEV相互作用，药物组合物和治疗用途的化合物
公开(公告)号：US08252786B2
公开(公告)日：2012-08-28
申请号：US12309429
申请日：2007-03-07
申请人： Timothy Thomson Okatsu , Johanna Scheper Sigmund , Ángel Messeguer Peypoch , Ángel Ramírez Ortiz , María Luz Ortiz Melguizo, legal representative , Ma Carmen Fabrega Claveria, legal representative , Gloria Sanclimens Pérez de Rozas , Isabel Masip Masip , Alejandra Moure Fernández , Domingo González Ruiz , Antonio Morreale de León
发明人： Timothy Thomson Okatsu , Johanna Scheper Sigmund , Ángel Messeguer Peypoch , Ángel Ramírez Ortiz , Gloria Sanclimens Pérez de Rozas , Isabel Masip Masip , Alejandra Moure Fernández , Domingo González Ruiz , Antonio Morreale de León
IPC分类号： A61K31/5513 , A61K31/496 , A61K31/495 , C07D243/08 , C07D295/04 , C07D403/06
CPC分类号： C07D401/12 , C07D241/08 , C07D243/08
摘要： The invention relates to a compound (I) wherein R is a heterocyclyl radical; R1 and R2 are independently H or alkyl; R3 is H, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, aryl, arylalkyl, heterocyclyl or heterocyclylalkyl; R4 and R5 are independently H or alkyl; q is a number selected from 0 and 1; and the salts, solvates, prodrugs or stereoisomers thereof having inhibitory activity for UBC13-UEV interactions and which can be used in the production of pharmaceutical compositions intended for antitumor therapy or the treatment and/or prophylaxis of diseases associated to metabolic pathways involving the UBC13 enzyme, metabolic pathways involving transcriptional factor NF-κB, or pathways involving PCNA or RAD6. R—(CR1R2)q-CO—N(R3)—C(R4R5)—CO—NH2 (I)
摘要翻译：本发明涉及其中R是杂环基的化合物（I）; R1和R2独立地为H或烷基; R3是H，烷基，环烷基，环烷基烷基，烯基，芳基，芳基烷基，杂环基或杂环基烷基; R4和R5独立地是H或烷基; q是选自0和1的数字; 其具有对UBC13-UEV相互作用具有抑制活性的盐，溶剂合物，前体药物或立体异构体，其可用于制备用于抗肿瘤治疗或治疗和/或预防涉及UBC13酶的代谢途径相关疾病的药物组合物涉及转录因子NF-κB或涉及PCNA或RAD6的途径的代谢途径。 R-（CR1R2）q-CO-N（R3）-C（R4R5）-CO-NH2（I）

9. 发明申请

US20060013963A1 Foam composite 有权
公开(公告)号：US20060013963A1
公开(公告)日：2006-01-19
申请号：US11230964
申请日：2005-09-20
申请人： Timothy Thomson
发明人： Timothy Thomson
IPC分类号： C08J9/28 , C08F2/46
CPC分类号： C08J9/405 , B32B5/18 , C08J9/0009 , C08J9/365 , C08J9/42 , C08J2205/05 , C08J2375/04 , C08J2475/00 , Y10T428/249953 , Y10T428/249954 , Y10T428/249955 , Y10T428/249958 , Y10T428/24996 , Y10T428/249978 , Y10T428/249979 , Y10T428/249981 , Y10T428/249986 , Y10T428/249991
摘要： A foam composite made up of a scaffold of an open cell hydrophobic material having plurality of surfaces defining a plurality of pores, and a coating of a substantially hydrophilic foam material disposed upon the surfaces of the hydrophobic foam. The resulting foam composite exhibits structural characteristics of the hydrophobic foam and absorbency characteristics of the hydrophilic foam.

10. 发明授权

US6117296A Electrically controlled contractile polymer composite 失效
标题翻译：电控收缩聚合物复合材料
公开(公告)号：US6117296A
公开(公告)日：2000-09-12
申请号：US121075
申请日：1998-07-21
申请人： Timothy Thomson
发明人： Timothy Thomson
IPC分类号： F03G7/00 , H02N11/00 , C25B9/00
CPC分类号： H02N11/006 , F03G7/005
摘要： An electrically controlled polymer composite which, when acted upon by an electric current, contracts or relaxes. It can also serve as a smart drug delivery device. The polymer composite is a series of hydrogel layers, each of which serve a particular purpose. A nonionic layer serves as a reservoir for an ionic salt while layers on either side can be anionic hydrogels and cationic gel. The invention can include an imbedded strain gauge by which the contractions or relaxations are monitored and controlled. The device is capable of being controlled by a computer with data acquisition and control capabilities.
摘要翻译：电控聚合物复合材料，当被电流作用时收缩或松弛。它也可以作为一种智能药物输送装置。聚合物复合材料是一系列水凝胶层，每层都有特殊用途。非离子层用作离子盐的储存器，而任一侧的层可以是阴离子水凝胶和阳离子凝胶。本发明可以包括嵌入式应变计，通过该应变计监测和控制收缩或松弛。该设备能够由具有数据采集和控制能力的计算机控制。

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