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    • 1. 发明申请
    • METHOD FOR SPATIALLY MANIPULATING A MICROSCOPIC OBJECT AND DEVICE FOR CONDUCTING SAID METHOD
    • 用于空间控制微观物体的方法和用于引导方法的装置
    • US20130105034A1
    • 2013-05-02
    • US13580936
    • 2011-02-07
    • Michael GabiJanos VoeroesStefan Pablo DoerigPascal BehrPhillipp StiefelThomaso ZambelliJulia Vorholt-Zambelli
    • Michael GabiJanos VoeroesStefan Pablo DoerigPascal BehrPhillipp StiefelThomaso ZambelliJulia Vorholt-Zambelli
    • B65B1/04
    • B65B1/04B82Y5/00B82Y30/00B82Y35/00C12M33/04G01Q60/38G01Q80/00
    • The invention relates to a method for spatially manipulating a microscopic object (20,23,33), said method comprising the steps of providing a cantilever (12) having a tip with an opening (19) and a microchannel (15) extending through the cantilever (12) in its longitudinal direction, said microchannel (15) being fluidly connected to the opening (19) at the tip of the cantilever; providing suspension means for holding the cantilever (12) and spatially moving the cantilever along a predetermined spatial path; providing pressurizing means for applying a predetermined pressure to the microchannel (15) within the cantilever; moving the cantilever (12) with its tip to the microscopic object (20,23,33) to be spatially manipulated, such that the opening (19) of the tip is adjacent to the microscopic object (20,23,33); picking up, with said cantilever (12), a part of the microscopic object (20,23,33) or the microscopic object (20,23,33) as a whole by reducing the pressure within the microchannel (15) relative to the pressure outside the tip of the cantilever (12); and moving said part of the microscopic object (20,23,33) or said microscopic object (20,23,33) as a whole along a predetermined spatial path by means of the cantilever (12).
    • 本发明涉及一种用于空间操纵微观物体(20,23,33)的方法,所述方法包括以下步骤:提供具有尖端的悬臂(12),所述悬臂具有开口(19)和延伸穿过所述孔的微通道(15) 悬臂(12)在其纵向方向上,所述微通道(15)在悬臂的尖端处流体地连接到开口(19); 提供用于保持悬臂(12)并沿预定空间路径空间移动悬臂的悬挂装置; 提供用于向悬臂内的微通道(15)施加预定压力的加压装置; 将悬臂(12)的尖端移动到微观物体(20,23,33)以进行空间操作,使得尖端的开口(19)与微观物体(20,23,33)相邻; 通过减小微通道(15)内的压力相对于所述微通道(15)中的压力,与所述悬臂(12)一起拾取所述微观物体(20,23,33)或所述微观物体(20,23,33)的整体的一部分 悬臂(12)尖端外的压力; 并且通过所述悬臂(12)沿预定的空间路径整体移动所述微观物体(20,23,33)或所述微观物体(20,23,33)的所述部分。