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1. 发明授权

US06297194B1 Production of phosphonopyrazoles 失效
标题翻译：膦吡唑的生产
公开(公告)号：US06297194B1
公开(公告)日：2001-10-02
申请号：US09497017
申请日：2000-02-02
申请人： Paula C. Miller , Jane M. Curtis , John M. Molyneaux , Thomas J. Owen
发明人： Paula C. Miller , Jane M. Curtis , John M. Molyneaux , Thomas J. Owen
IPC分类号： A01N5724
CPC分类号： A01N57/24 , A01N57/32 , C07F9/65031
摘要： Pyrazole compounds with activity as chemical hybridizing agents and methods for synthesis of such compounds are disclosed. These compounds are useful in producing hybrid wheat (Triticum aesativum) and other crops.
摘要翻译：公开了具有作为化学杂交剂活性的吡唑化合物及其合成方法。这些化合物可用于生产杂交小麦（Triticum aesativum）和其他作物。

2. 发明授权

US4755138A Fluidized bed calciner apparatus 失效
标题翻译：流化床煅烧设备
公开(公告)号：US4755138A
公开(公告)日：1988-07-05
申请号：US47569
申请日：1987-04-23
申请人： Thomas J. Owen , Michael J. Klem, Jr. , Robert J. Cash
发明人： Thomas J. Owen , Michael J. Klem, Jr. , Robert J. Cash
IPC分类号： B01J8/18 , B01J8/24 , B01J8/44 , G21F9/14 , F27B15/20
CPC分类号： B01J8/1836 , B01J8/1827 , B01J8/44 , G21F9/14 , B01J2208/00407 , B01J2208/00415
摘要： An apparatus for remotely calcining a slurry or solution feed stream of toxic or hazardous material, such as ammonium diurante slurry or uranyl nitrate solution, is disclosed. The calcining apparatus includes a vertical substantially cylindrical inner shell disposed in a vertical substantially cylindrical outer shell, in which inner shell is disposed a fluidized bed comprising the feed stream material to be calcined and spherical beads to aid in heat transfer. Extending through the outer and inner shells is a feed nozzle for delivering feed material or a cleaning chemical to the beads. Disposed in and extending across the lower portion of the inner shell and upstream of the fluidized bed is a support member for supporting the fluidized bed, the support member having uniform slots for directing uniform gas flow to the fluidized bed from a fluidizing gas orifice disposed upstream of the support member. Disposed in the lower portion of the inner shell are a plurality of internal electric resistance heaters for heating the fluidized bed. Disposed circumferentially about the outside length of the inner shell are a plurality of external heaters for heating the inner shell thereby heating the fluidized bed. Further, connected to the internal and external heaters is a means for maintaining the fluidized bed temperature to within plus or minus approximately 25.degree. C. of a predetermined bed temperature. Disposed about the external heaters is the outer shell for providing radiative heat reflection back to the inner shell.
摘要翻译：公开了一种用于远程煅烧有毒或有害物质的浆液或溶液进料流的设备，例如铵盐或硝酸铀酰溶液。煅烧装置包括垂直的基本上圆柱形的内壳，其设置在垂直的基本上圆柱形的外壳中，其中内壳设置有流化床，流化床包括待煅烧的进料流材料和球形珠子以辅助热传递。通过外壳和内壳延伸的是用于将进料或清洁化学品输送到珠的进料喷嘴。设置在并延伸穿过内壳的下部并在流化床的上游延伸的是用于支撑流化床的支撑构件，支撑构件具有均匀的狭槽，用于将均匀的气体流从设置在上游的流化气体孔口引导到流化床的支撑构件。设置在内壳的下部的是用于加热流化床的多个内部电阻加热器。围绕内壳的外部长度周向地设置有多个用于加热内壳的外部加热器，从而加热流化床。此外，连接到内部和外部加热器是将流化床温度保持在预定床温度的±25℃以内的方法。围绕外部加热器设置的是外壳，用于向内壳提供辐射热反射。

3. 发明授权

US07186743B2 Substituted pyrazolyl compounds for the treatment of inflammation 失效
标题翻译：用于治疗炎症的取代的吡唑基化合物
公开(公告)号：US07186743B2
公开(公告)日：2007-03-06
申请号：US11113926
申请日：2005-04-25
申请人： Arija A. Bergmanis , Michael Clare , Joyce Z. Crich , Lifeng Geng , Timothy J. Hagen , Gunnar J. Hanson , Stephen C. Houdek , He Huang , Donna M. Iula , Francis J. Koszyk , Shuyuan Liao , Scott B. Mohler , Maria Nguyen , Richard A. Partis , Michael A. Stealey , Michael B. Tollefson , Richard M. Weier , Xiangdong Xu , Dominique Bonafoux , Theresa R. Fletcher , Bruce C Hamper , Patrick J. Lennon , Subo Liao , Suzanne Metz , David S. Oburn , Thomas J. Owen , Angela M. Scates , Michael L. Vazquez , Serge G. Wolfson
发明人： Arija A. Bergmanis , Michael Clare , Joyce Z. Crich , Lifeng Geng , Timothy J. Hagen , Gunnar J. Hanson , Stephen C. Houdek , He Huang , Donna M. Iula , Francis J. Koszyk , Shuyuan Liao , Scott B. Mohler , Maria Nguyen , Richard A. Partis , Michael A. Stealey , Michael B. Tollefson , Richard M. Weier , Xiangdong Xu , Dominique Bonafoux , Theresa R. Fletcher , Bruce C Hamper , Patrick J. Lennon , Subo Liao , Suzanne Metz , David S. Oburn , Thomas J. Owen , Angela M. Scates , Michael L. Vazquez , Serge G. Wolfson
IPC分类号： A61K31/416 , A61K31/454 , A61K31/5395 , A61K31/429 , A61K31/433 , A61K31/506 , A61K31/496
CPC分类号： C07D403/12 , C07D231/54 , C07D333/62 , C07D401/12 , C07D401/14 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要： The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthritis.
摘要翻译：本发明涉及取代的吡唑基衍生物，包含这些的组合物，中间体，制备取代的吡唑基衍生物的方法，以及用于治疗癌症，炎症和炎症相关疾病如关节炎的方法。

4. 发明授权

US5681925A Trifunctional antithrombin and antiplatelet peptides 失效
标题翻译：三功能抗凝血酶和抗血小板肽
公开(公告)号：US5681925A
公开(公告)日：1997-10-28
申请号：US502989
申请日：1995-07-17
申请人： Robert J. Broersma, Jr. , Thomas J. Owen , John L. Krstenansky
发明人： Robert J. Broersma, Jr. , Thomas J. Owen , John L. Krstenansky
IPC分类号： A61K38/00 , A61K38/46 , A61K38/55 , A61P7/02 , C07K5/08 , C07K7/00 , C07K14/745 , C07K14/75 , C07K14/815 , A61K38/36 , A61K38/16 , C07K14/00
CPC分类号： C07K14/815 , C07K14/75 , A61K38/00
摘要： Novel compounds which contain a thrombin catalytic-site inhibitor coupled with an anion binding exosite associating moiety via an RGD-X bridging sequence are trifunctional anticoagulants useful in treating venous or arterial thrombotic conditions.
摘要翻译：含有通过RGD-X桥连序列与阴离子结合外部位点缔合部分偶联的凝血酶催化位点抑制剂的新型化合物是可用于治疗静脉或动脉血栓形成状况的三功能抗凝剂。

6. 发明授权

US06765138B1 Register system for contrabassoon 失效
标题翻译：注册系统进行违禁
公开(公告)号：US06765138B1
公开(公告)日：2004-07-20
申请号：US10272365
申请日：2002-10-16
申请人： Arlen Fast , Thomas J. Owen, Jr.
发明人： Arlen Fast , Thomas J. Owen, Jr.
IPC分类号： G10D700
CPC分类号： G10D7/063 , G10D9/043
摘要： A contrabassoon has a body, a tuning slide, a bocal pipe and a novel register system. The body, tuning slide and bocal pipe form a tube having a continuous bore. The register system comprises 5 vent holes formed in the tube. Key mechanisms for selectively opening and closing the vent holes are described. The contrabassoon further comprises linkage to selectively operate a low E vent pad, and an alternative C-sharp tone hole, with accompanying key mechanism.
摘要翻译：违禁品有一个身体，一个调子滑块，一个主要的管道和一个新的注册系统。主体，调音滑块和焦点管形成具有连续孔的管。配准系统包括形成在管中的5个通气孔。描述了用于选择性地打开和关闭排气孔的关键机构。反铲机还包括连接以选择性地操作低E排气垫和替代的C尖锐音调孔，伴随关键机构。

7. 发明授权

US5521156A Cyclic neurokinin A antagonists 失效
标题翻译：循环神经激肽A拮抗剂
公开(公告)号：US5521156A
公开(公告)日：1996-05-28
申请号：US191571
申请日：1994-02-03
申请人： Thomas J. Owen , Elizabeth M. Kudlacz , Scott L. Harbeson , Stephen H. Buck
发明人： Thomas J. Owen , Elizabeth M. Kudlacz , Scott L. Harbeson , Stephen H. Buck
IPC分类号： A61K38/00 , A61K38/55 , A61P11/00 , A61P11/06 , A61P25/04 , A61P29/00 , A61P43/00 , C07K7/22 , C07K7/64 , A61K38/12
CPC分类号： C07K7/22 , A61K38/00 , Y10S930/27
摘要： Antagonists of neurokinin A which are novel cyclic hexapeptide and octapeptide compounds are described. The antagonism is confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions in which neurokinin A is implicated is also described.
摘要翻译：描述了新型环状六肽和八肽化合物的神经激肽A的拮抗剂。使用常规竞争性结合和生物化学测定以及常规生理测试证实拮抗作用，并且还描述了在涉及神经激肽A的各种情况下使用这些衍生物。

8. 发明授权

US4154546A Pin and socket joint 失效
标题翻译：销和插座接头
公开(公告)号：US4154546A
公开(公告)日：1979-05-15
申请号：US914864
申请日：1978-06-12
申请人： Neville L. Merrick , Thomas J. Owen
发明人： Neville L. Merrick , Thomas J. Owen
IPC分类号： B60G7/00 , F16C11/06 , F16C11/08
CPC分类号： F16C11/068 , B60G7/005 , F16C11/0623 , F16C11/0671 , Y10S277/928 , Y10T403/32729 , Y10T403/52
摘要： The invention relates to pin and socket joints for use in the steering and suspension systems of automobiles. The head of the pin is housed in a socket having an aperture through which the pin extends, the aperture being sealed by an annular boot having peripheral portions sealing against the pin and socket respectively.One of the peripheral portions is engaged in a groove in the pin or socket and the said one peripheral portion has interior passageways leading from the interior of the boot to the base of the groove and exterior passageways leading from the base of the groove to the exterior of the boot.These passageways facilitate the rapid escape of grease from the boot during excessive power filling of grease into the joint so that the boot is not disengaged from the groove.
摘要翻译：本发明涉及用于汽车转向和悬挂系统的销和插座接头。销的头部容纳在具有孔的插座中，销的延伸穿过该孔，该孔由环形护罩密封，环形护罩具有分别密封销钉和插座的周边部分。

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