专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070148747A1 Genes involved in polyketide synthase pathways and uses thereof 有权
公开(公告)号：US20070148747A1
公开(公告)日：2007-06-28
申请号：US11711809
申请日：2007-02-27
申请人： Pradip Mukerji , Suzette Pereira
发明人： Pradip Mukerji , Suzette Pereira
IPC分类号： C12P7/64 , C07H21/04 , C12N9/10 , C12N1/10
CPC分类号： C12N15/8247 , C12N9/1029 , C12N15/52
摘要： The subject invention relates to isolated nucleic acid sequences or genes involved in polyketide synthase (PKS) biosynthetic pathways. In particular, such pathways are involved in the production of polyunsaturated fatty acids (PUFAs) such as, for example, Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA). Specifically, the invention relates to isolating nucleic acid sequences encoding proteins involved in eukaryotic PUFA-PKS systems and to uses of these genes and encoded proteins in PUFA-PKS systems, in heterologous hosts, for the production of PUFAs such as EPA and DHA.

2. 发明申请

US20050003442A1 Delta4-desaturase genes and uses thereof 有权
标题翻译： Δ4-去饱和酶基因及其用途
公开(公告)号：US20050003442A1
公开(公告)日：2005-01-06
申请号：US10913271
申请日：2004-08-06
申请人： Pradip Mukerji , Jennifer Thurmond , Yung-Sheng Huang , Tapas Das , Amanda Leonard , Suzette Pereira
发明人： Pradip Mukerji , Jennifer Thurmond , Yung-Sheng Huang , Tapas Das , Amanda Leonard , Suzette Pereira
IPC分类号： A01H5/00 , A23D9/00 , A23K1/16 , A23L1/164 , A23L1/187 , A61K31/202 , A61K38/00 , A61P3/02 , C12N1/19 , C12N5/02 , C12N5/10 , C12N9/02 , C12N15/09 , C12P7/64 , C12Q1/68 , C07H21/04 , C12N1/14 , C12N9/04
CPC分类号： C12N9/0083 , A23D9/00 , A23K20/158 , A23L7/126 , A23L9/12 , A61K38/00 , C12P7/6427 , C12P7/6472
摘要： The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “Δ4-desaturase”). In particular, Δ4-desaturase may be utilized, for example, in the conversion of adrenic acid to ω6-docosapentaenoic acid and in the conversion of ω3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：本发明涉及鉴定涉及碳4处多不饱和脂肪酸去饱和的基因（即“Δ4-去饱和酶”）。特别地，可以使用Δ4-去饱和酶，例如，将肾上腺酸转化为ω6-二十二碳五烯酸，并将ω3-二十二碳五烯酸转化成二十二碳六烯酸。通过使用酶产生的多不饱和脂肪酸可以加入到药物组合物，营养组合物，动物饲料中，以及其它产品如化妆品中。

3. 发明授权

US08188335B2 Δ9-elongase for production of polyunsaturated fatty acid-enriched oils 有权
标题翻译：＆Dgr; 9-延伸酶用于生产多不饱和脂肪酸富集油
公开(公告)号：US08188335B2
公开(公告)日：2012-05-29
申请号：US12505293
申请日：2009-07-17
申请人： Suzette Pereira , Tapas Das , Padmavathy Krishnan , Pradip Mukerji
发明人： Suzette Pereira , Tapas Das , Padmavathy Krishnan , Pradip Mukerji
IPC分类号： A01H1/00 , A01H5/00 , C12N5/14 , C12N5/16 , C07H21/04
CPC分类号： C12N9/0071 , C12N9/93 , C12N15/8247
摘要： The present disclosure relates to isolated polynucleotides encoding a delta 9-elongase, delta 9-elongases encoded by the isolated polynucleotides, expression vectors comprising the isolated polynucleotides, host cells comprising the expression vectors, and methods for producing delta 9-elongase and polyunsaturated fatty acids.
摘要翻译：本公开涉及编码由分离的多核苷酸编码的δ9-延伸酶，δ9-延伸酶，包含分离的多核苷酸的表达载体，包含表达载体的宿主细胞和用于产生δ9-延伸酶和多不饱和脂肪酸的方法的分离的多核苷酸。

4. 发明申请

US20110016585A1 NOVEL DELTA9-ELONGASE FOR PRODUCTION OF POLYUNSATURATED FATTY ACID-ENRICHED OILS 有权
标题翻译：用于生产聚氨酯脂肪酸的油的新型DELTA9-ELONGASE
公开(公告)号：US20110016585A1
公开(公告)日：2011-01-20
申请号：US12505293
申请日：2009-07-17
申请人： Suzette Pereira , Tapas Das , Padmavathy Krishnan , Pradip Mukerji
发明人： Suzette Pereira , Tapas Das , Padmavathy Krishnan , Pradip Mukerji
IPC分类号： A01H1/00 , C07H21/04 , C12N9/10 , C12N15/63 , C12N5/10 , C12N1/15 , A01H5/00 , C12P21/06 , C12P7/64
CPC分类号： C12N9/0071 , C12N9/93 , C12N15/8247
摘要： The present disclosure relates to isolated polynucleotides encoding a delta 9-elongase, delta 9-elongases encoded by the isolated polynucleotides, expression vectors comprising the isolated polynucleotides, host cells comprising the expression vectors, and methods for producing delta 9-elongase and polyunsaturated fatty acids.
摘要翻译：本公开涉及编码由分离的多核苷酸编码的δ9-延伸酶，δ9-延伸酶，包含分离的多核苷酸的表达载体，包含表达载体的宿主细胞和用于产生δ9-延伸酶和多不饱和脂肪酸的方法的分离的多核苷酸。

5. 发明申请

US20050005329A1 Delta4-desaturase genes and uses thereof 有权
公开(公告)号：US20050005329A1
公开(公告)日：2005-01-06
申请号：US10913779
申请日：2004-08-06
申请人： Pradip Mukerji , Jennifer Thurmond , Yung-Sheng Huang , Tapas Das , Amanda Leonard , Suzette Pereira
发明人： Pradip Mukerji , Jennifer Thurmond , Yung-Sheng Huang , Tapas Das , Amanda Leonard , Suzette Pereira
IPC分类号： A01H5/00 , A23D9/00 , A23K1/16 , A23L1/164 , A23L1/187 , A61K31/202 , A61K38/00 , A61P3/02 , C12N1/19 , C12N5/02 , C12N5/10 , C12N9/02 , C12N15/09 , C12P7/64 , C07H21/04 , A23D7/00 , A61K35/78 , C07K14/00 , C12N15/00 , C12N15/63 , C12N15/82 , C12N15/87
CPC分类号： C12N9/0083 , A23D9/00 , A23K20/158 , A23L7/126 , A23L9/12 , A61K38/00 , C12P7/6427 , C12P7/6472
摘要： The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “Δ4-desaturase”). In particular, Δ4-desaturase may be utilized, for example, in the conversion of adrenic acid to ω6-docosapentaenoic acid and in the conversion of ω3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.

6. 发明申请

US20060048244A1 Delta6-desaturase genes and uses thereof 失效
标题翻译： Delta6-去饱和酶基因及其用途
公开(公告)号：US20060048244A1
公开(公告)日：2006-03-02
申请号：US10931626
申请日：2004-09-01
申请人： Pradip Mukerji , Yung-Sheng Huang , Amanda Leonard , Suzette Pereira , Jennifer Thurmond
发明人： Pradip Mukerji , Yung-Sheng Huang , Amanda Leonard , Suzette Pereira , Jennifer Thurmond
IPC分类号： A01H1/00 , C07H21/04 , C12N9/04 , C12N1/14 , C12N15/82
CPC分类号： C12N15/8247 , C12N9/0083
摘要： The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 6 (i.e., “Δ6-desaturase”). In particular, Δ6-desaturase may be utilized, for example, in the conversion of linoleic acid to γ-linolenic acid and in the conversion of α-linolenic acid stearidonic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：本发明涉及鉴定参与碳6多不饱和脂肪酸脱饱和基因（即“Δ6-去饱和酶”）的基因。特别地，可以使用Δ6-去饱和酶，例如，将亚油酸转化为γ-亚麻酸和在α-亚麻酸十八碳四烯酸的转化中。通过使用酶产生的多不饱和脂肪酸可以加入到药物组合物，营养组合物，动物饲料中，以及其它产品如化妆品中。

7. 发明申请

US20050014231A1 Genes involved in polyketide synthase pathways and uses thereof 有权
标题翻译：涉及聚酮化合物合酶途径的基因及其用途
公开(公告)号：US20050014231A1
公开(公告)日：2005-01-20
申请号：US10619532
申请日：2003-07-15
申请人： Pradip Mukerji , Suzette Pereira
发明人： Pradip Mukerji , Suzette Pereira
IPC分类号： C12N1/21 , C12N9/10 , C12N15/52 , C12N15/82 , C12P19/60 , C07H21/04 , C12P7/64
CPC分类号： C12N15/8247 , C12N9/1029 , C12N15/52
摘要： The subject invention relates to isolated nucleic acid sequences or genes involved in polyketide synthase (PKS) biosynthetic pathways. In particular, such pathways are involved in the production of polyunsaturated fatty acids (PUFAs) such as, for example, Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA). Specifically, the invention relates to isolating nucleic acid sequences encoding proteins involved in eukaryotic PUFA-PKS systems and to uses of these genes and encoded proteins in PUFA-PKS systems, in heterologous hosts, for the production of PUFAs such as EPA and DHA.
摘要翻译：本发明涉及分离的核酸序列或参与聚酮化合物合酶（PKS）生物合成途径的基因。特别地，这些途径涉及多不饱和脂肪酸（PUFA）的生产，例如二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）。具体地，本发明涉及分离编码参与真核PUFA-PKS系统的蛋白质的核酸序列，以及这些基因和编码的蛋白质在异源宿主中的PUFA-PKS系统中用于生产PUFA（例如EPA和DHA）的用途。

8. 发明申请

US20070124837A1 DESATURASE GENES, ENZYMES ENCODED THEREBY, AND USES THEREOF 有权
标题翻译：去饱和基因，编码的酶，及其用途
公开(公告)号：US20070124837A1
公开(公告)日：2007-05-31
申请号：US11621446
申请日：2007-01-09
申请人： Pradip Mukerji , Suzette Pereira , Yung-Sheng Huang
发明人： Pradip Mukerji , Suzette Pereira , Yung-Sheng Huang
IPC分类号： A01H1/00 , C07H21/04
CPC分类号： C12N9/0083 , C12P7/6427 , C12P7/6472
摘要： Disclosed are isolated polynucleotides encoding an omega-3 desaturase and a delta-12 desaturase, the enzymes encoded by the isolated polynucleotides, vectors containing the isolated polynucleotides, transgenic hosts that contain the isolated polynucleotides that express the enzymes encoded thereby, methods for producing the desaturase enzymes, and method of using the enzymes to make polyunsaturated fatty acids. The isolated polynucleotides are derived from a fungus, Saprolegnia diclina (ATCC 56851). In particular, omega-3-desaturase may be utilized, for example, in the conversion of arachidonic acid (AA) to eicosapentaenoic acid (EPA). Delta-12 desaturase may be used, for example, in the conversion of oleic acid (OA) to linoleic (LA). EPA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：公开了编码ω-3去饱和酶和δ-12去饱和酶的分离的多核苷酸，由分离的多核苷酸编码的酶，含有分离的多核苷酸的载体，含有表达由其编码的酶的分离的多核苷酸的转基因宿主，用于产生去饱和酶的方法酶和使用酶制备多不饱和脂肪酸的方法。分离的多核苷酸衍生自真菌Saprolegnia diclina（ATCC 56851）。特别地，ω-3-去饱和酶可用于例如花生四烯酸（AA）转化为二十碳五烯酸（EPA）。 Δ-12去饱和酶可以用于例如将油酸（OA）转化为亚油酸（LA）。由此产生的EPA或多不饱和脂肪酸可以加入到药物组合物，营养组合物，动物饲料中，以及其它产品如化妆品中。

9. 发明申请

US20050009140A1 Elongase genes and uses thereof 有权
标题翻译：延长酶基因及其用途
公开(公告)号：US20050009140A1
公开(公告)日：2005-01-13
申请号：US10912446
申请日：2004-08-05
申请人： Pradip Mukerji , Amanda Leonard , Yung-Sheng Huang , Suzette Pereira
发明人： Pradip Mukerji , Amanda Leonard , Yung-Sheng Huang , Suzette Pereira
IPC分类号： A01H5/00 , A23D9/00 , A23K1/16 , A61K8/30 , A61K8/36 , A61K8/60 , A61K8/64 , A61K31/202 , A61K38/00 , A61P3/02 , A61P3/04 , A61P3/10 , A61P7/00 , A61P7/02 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/04 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/16 , A61P19/02 , A61P19/10 , A61P25/00 , A61P29/00 , A61P31/18 , A61Q19/00 , C07H21/04 , C12N1/12 , C12N1/15 , C12N1/19 , C12N1/20 , C12N1/21 , C12N5/00 , C12N5/10 , C12N9/00 , C12N9/10 , C12N15/00 , C12N15/09 , C12N15/82 , C12P7/64 , C12P21/06
CPC分类号： A23D9/00 , A01K2217/05 , A23K20/158 , A61K8/361 , A61K8/606 , A61K8/64 , A61K31/202 , A61K38/00 , A61K2800/86 , A61Q19/00 , C12N9/1029 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated acids (i.e., “elongases”) and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogamma linolenic acid (DGLA) and in the conversion of AA to adrenic acid (ADA), or eicosapentaenoic acid (EPA) to ω3-docosapentaenoic acid (DPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachidonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ω6-docosapentaenoic acid or ω3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：本发明涉及鉴定涉及多不饱和酸延伸的几种基因（即“延伸酶”）及其应用。这些基因中至少有两个也参与单不饱和脂肪酸的延伸。特别地，延长酶用于将γ-亚麻酸（GLA）转化为二亚麻酸（DGLA）和将AA转化为肾上腺素（ADA）或二十碳五烯酸（EPA）转化为ω-二十二碳五烯酸（DPA）。 DGLA可用于生产多不饱和脂肪酸，例如花生四烯酸（AA），二十二碳六烯酸（DHA），EPA，肾上腺素，ω6-二十二碳五烯酸或ω3-二十二碳五烯酸，其可加入到药物组合物中，营养组合物，动物饲料，以及化妆品等其他产品。

10. 发明申请

US20050005328A1 Delta4-desaturase genes and uses thereof 有权
公开(公告)号：US20050005328A1
公开(公告)日：2005-01-06
申请号：US10913226
申请日：2004-08-06
申请人： Pradip Mukerji , Jennifer Thurmond , Yung-Sheng Huang , Tapas Das , Amanda Leonard , Suzette Pereira
发明人： Pradip Mukerji , Jennifer Thurmond , Yung-Sheng Huang , Tapas Das , Amanda Leonard , Suzette Pereira
IPC分类号： A01H5/00 , A23D9/00 , A23K1/16 , A23L1/164 , A23L1/187 , A61K31/202 , A61K38/00 , A61P3/02 , C12N1/19 , C12N5/02 , C12N5/10 , C12N9/02 , C12N15/09 , C12P7/64 , A01H1/00 , C07H21/04 , C12N5/04 , C12N9/04 , C12N15/82 , C12Q1/68
CPC分类号： C12N9/0083 , A23D9/00 , A23K20/158 , A23L7/126 , A23L9/12 , A61K38/00 , C12P7/6427 , C12P7/6472
摘要： The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “Δ4-desaturase”). In particular, Δ4-desaturase may be utilized, for example, in the conversion of adrenic acid to ω6-docosapentaenoic acid and in the conversion of ω3-docosapentaenoic acid to docosahexaenoic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式