会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 4. 发明申请
    • Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containingthem
    • 被噻吩并恶唑衍生物取代的苯并吡喃衍生物,其药学上可接受的盐,其制剂和药物组合物
    • US20070093481A1
    • 2007-04-26
    • US10558111
    • 2004-05-28
    • Sun Kyung Hwang
    • Sun Kyung Hwang
    • A61K31/535C07D211/68C07D211/80C07D277/82C07D213/02
    • C07D413/04
    • The present invention relates to benzopyran derivatives substituted with a thioxobenzoxazole derivative, or pharmaceutically acceptable salts thereof, processes for preparing the same and a pharmaceutical composition containing the above as an effective ingredient Benzopyran derivatives substituted with thioxobenzoxazole derivatives, represented in , have the function of protecting heart from ischemia-reperfusion both in vivo and in vitro, so that a pharmaceutical composition containing benzopyran derivatives substituted with thioxobenzoxoazole derivatives or pharmaceutically acceptable salts thereof of the present invention as an effective ingredient can be effectively used for the protection of tissues influenced by ischemia-reperfusion, for example, for the protection of heart, nervous cells, brain, retinal cells, storage organs, etc, and for the treatment of diseases caused by ischemia-reperfusion.
    • 本发明涉及用硫代苯并恶唑衍生物取代的苯并吡喃衍生物或其药学上可接受的盐,其制备方法和含有上述作为有效成分的药物组合物用<式1>所示的噻吩并恶唑衍生物取代的苯并吡喃衍生物具有 在体内和体外保护心脏免于缺血 - 再灌注的功能,使得含有本发明的噻唑并苯并恶唑衍生物或其可药用盐取代的苯并吡喃衍生物的药物组合物作为有效成分可以有效地用于保护组织 受缺血再灌注的影响,例如保护心脏,神经细胞,脑,视网膜细胞,储存器官等,以及治疗由局部缺血 - 再灌注引起的疾病。