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1. 发明申请

US20090048608A1 TORIC LENSES ALIGNMENT USING PRE-OPERATIVE IMAGES 有权
标题翻译：使用预先操作的图像的TORIC镜头对齐
公开(公告)号：US20090048608A1
公开(公告)日：2009-02-19
申请号：US12189482
申请日：2008-08-11
申请人： Mikhail Boukhny , Steven Bott
发明人： Mikhail Boukhny , Steven Bott
IPC分类号： A61F9/00 , A61B19/00
CPC分类号： A61F2/16 , A61B3/107 , A61F2/1645 , A61F2/1662
摘要： Proper selection and centering of an intraocular lens (IOL) is provided. An image of an eye, which may be captured during pre-operative tests and provided to a program operable to calculate the power and axis orientation of the IOL, is used to determine the location and orientation of the IOL. This produces an output or placement guide used to properly center and orient an IOL within the eye.
摘要翻译：提供人工晶状体（IOL）的适当选择和定中心。可以在术前测试中捕获并提供给可操作以计算IOL的功率和轴方向的程序的眼睛的图像用于确定IOL的位置和取向。这产生用于使IOL在眼睛内正确居中和定向的输出或放置指南。

2. 发明授权

US5871946A Method for determining activity of enzymes in metabolically active whole cells 失效
标题翻译：测定代谢活性全细胞中酶活性的方法
公开(公告)号：US5871946A
公开(公告)日：1999-02-16
申请号：US444056
申请日：1995-05-18
申请人： Frank J. Lucas , Gerald E. Jaffe , Steven Bott , James H. Carter
发明人： Frank J. Lucas , Gerald E. Jaffe , Steven Bott , James H. Carter
IPC分类号： C12Q1/34 , G01N33/574 , C12Q1/02
CPC分类号： C12Q1/34 , G01N33/574 , Y10S435/962 , Y10S435/968
摘要： An assay compound or a salt thereof for assaying the activity of an enzyme inside a metabolically active whole cell is disclosed. The assay compound includes a leaving group and an indicator group. The leaving group is selected from the group comprising amino acids, peptides, saccharides, sulfates, phosphates, esters, phosphate esters, nucleotides, polynucleotides, nucleic acids, pyrimidines, purines, nucleosides, lipids and mixtures thereof. The indicator group is selected from compounds which have a first state when joined to the leaving group, and a second state when the leaving group is cleaved from the indicator group by the enzyme. Preferably, the indicator compounds are rhodamine 110, rhodol, and fluorescein and analogs of these compounds. A method of synthesizing the compound as well as methods of using these compounds to measure enzyme activity are also disclosed.
摘要翻译：公开了一种用于测定代谢活性整个细胞内的酶的活性的测定化合物或其盐。测定化合物包括离去基团和指示剂组。离去基团选自包括氨基酸，肽，糖，硫酸盐，磷酸盐，酯，磷酸酯，核苷酸，多核苷酸，核酸，嘧啶，嘌呤，核苷，脂质及其混合物的组。指示基团选自与离去基团连接时具有第一状态的化合物，当离去基团被酶从指示剂基团切割时的第二种状态。优选地，指示剂化合物是这些化合物的罗丹明110，rhodol和荧光素以及类似物。还公开了合成化合物的方法以及使用这些化合物测定酶活性的方法。

3. 发明授权

US08414123B2 Toric lenses alignment using pre-operative images 有权
标题翻译：使用术前图像的复眼镜片对准
公开(公告)号：US08414123B2
公开(公告)日：2013-04-09
申请号：US12189482
申请日：2008-08-11
申请人： Mikhail Boukhny , Steven Bott
发明人： Mikhail Boukhny , Steven Bott
IPC分类号： A61B3/10 , A61B3/00 , A61F9/00
CPC分类号： A61F2/16 , A61B3/107 , A61F2/1645 , A61F2/1662
摘要： Proper selection and centering of an intraocular lens (IOL) is provided. An image of an eye, which may be captured during pre-operative tests and provided to a program operable to calculate the power and axis orientation of the IOL, is used to determine the location and orientation of the IOL. This produces an output or placement guide used to properly center and orient an IOL within the eye.
摘要翻译：提供人工晶状体（IOL）的适当选择和定中心。可以在术前测试中捕获并提供给可操作以计算IOL的功率和轴方向的程序的眼睛的图像用于确定IOL的位置和取向。这产生用于使IOL在眼睛内正确居中和定向的输出或放置指南。

4. 发明申请

US20050137586A1 Hybrid eye tracking system and associated methods 审中-公开
标题翻译：混合眼动跟踪系统及相关方法
公开(公告)号：US20050137586A1
公开(公告)日：2005-06-23
申请号：US11020429
申请日：2004-12-22
申请人： Gary Gray , John Campin , Steven Bott , David Gibbs , George Pettit
发明人： Gary Gray , John Campin , Steven Bott , David Gibbs , George Pettit
IPC分类号： A61B18/20 , A61F9/008 , A61F9/01
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system and method for tracking ocular changes during a surgical procedure include directing an eye-safe optical beam toward an undilated, unparalyzed eye. A reflected optical beam is detected, and measurements are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency, and from them is calculated a change in the at least one geometric parameter. The calculated change is used to dynamically adjust the directing of laser beam shots during the surgery.
摘要翻译：用于在外科手术过程中跟踪眼睛变化的系统和方法包括将眼睛安全的光束引向未被剥离的未分析的眼睛。检测反射光束，并且基于预定频率的眼睛的至少一个几何参数的反射光束中包含的数据进行测量，并且根据它们计算至少一个几何参数的变化。计算出的变化用于在手术过程中动态调整激光束拍摄的指导。

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