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    • 3. 发明授权
    • DNA biosensor and methods for making and using the same
    • DNA生物传感器及其制造和使用方法
    • US07615780B2
    • 2009-11-10
    • US11427544
    • 2006-06-29
    • Steven Alfred TysoeEugene BarashAndrew David Pris
    • Steven Alfred TysoeEugene BarashAndrew David Pris
    • H01L23/58
    • H01S5/34333B82Y20/00H01S5/005H01S5/02248H01S5/18308H01S5/18338H01S5/18341
    • Disclosed herein are biosensors and methods for making and using the same. In one embodiment, the sensor for detecting an analyte comprises: a substrate, recognition elements specific for the analyte, an excitation source, a detector, a chamber located between the substrate and the excitation source and between the substrate and the detector, and an emission filter. The recognition elements are tethered to the substrate such that the recognition elements can be exposed to a sample. The excitation source is capable of emitting a first light having a first light peak intensity at a first wavelength, wherein the first light can excite a luminophore to emit a second light when the recognition elements interact with the analyte. The detector is capable of detecting the second light emitted by the luminophore. The emission filter is capable of filtering in a band gap that includes the first light peak intensity.
    • 本文公开了生物传感器及其制造和使用方法。 在一个实施例中,用于检测分析物的传感器包括:基底,对分析物特异的识别元件,激发源,检测器,位于基底和激发源之间以及基底和检测器之间的腔室,以及发射 过滤。 将识别元件束缚于基底,使得识别元件可以暴露于样品。 激发源能够发射具有第一波长的第一光峰强度的第一光,其中当识别元件与分析物相互作用时,第一光可以激发发光体以发射第二光。 检测器能够检测由发光体发出的第二光。 发射滤波器能够在包括第一光峰强度的带隙中进行滤波。