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1. 发明授权

US4574000A Artificial fallopian tube 失效
标题翻译：人造输卵管
公开(公告)号：US4574000A
公开(公告)日：1986-03-04
申请号：US644315
申请日：1984-08-24
申请人： Stephen K. Hunter
发明人： Stephen K. Hunter
IPC分类号： A61B17/435 , A61F2/04 , A61M25/00
CPC分类号： A61B17/435 , A61F2/04
摘要： The present invention is directed to methods and apparatus for artificially transporting an egg from an ovary to the uterus in a patient having dysfunctional natural fallopian tubes. A preferred embodiment of the apparatus of the present invention includes an ovisac in which one of the patient's ovaries is encapsulated in order to collect any ova discharged. A plurality of fluid supply tubes serve to wash the ova toward a tubular member that is secured in communication with the uterine cavity. In one embodiment, a reservoir of fluid and a programmable micropump are provided, both of which are adapted to be implanted in the patient. The method of the present invention advantageously comprises the initial step of charging the artificial fallopian tube with a solution of nutrients and sperm immediately prior to ovulation. After fertilization has had an opportunity to occur, nutrient solution is introduced into the fallopian tube in a continuous, but pulsatile manner at a rate that will cause the ovum to be ejected into the uterine cavity about two to three days after ovulation.
摘要翻译：本发明涉及用于在具有功能障碍的天然输卵管的患者中将卵子从卵巢人工运送到子宫的方法和装置。本发明的装置的一个优选实施例包括其中一个患者的卵巢被包封以便收集所排出的任何卵的监视。多个流体供应管用于将卵子朝向与子宫腔连通的管状构件。在一个实施例中，提供了流体储存器和可编程微型泵，两者都适于植入患者体内。本发明的方法有利地包括在排卵之前立即用营养物和精子的溶液装入人造输卵管的初始步骤。在受精有机会发生后，营养液以连续的，脉动的方式被引入输卵管，其排卵速率将在排卵后约2-3天内将卵子排出到子宫腔中。

2. 发明授权

US4557724A Apparatus and methods for minimizing cellular adhesion on peritoneal injection catheters 失效
标题翻译：用于最小化腹膜注射导管上的细胞粘附的装置和方法
公开(公告)号：US4557724A
公开(公告)日：1985-12-10
申请号：US522914
申请日：1983-08-12
申请人： Donald E. Gregonis , Robert L. Stephen , Dennis L. Coleman , Stephen K. Hunter , Barry K. Hanover , Jeffrey J. Harrow
发明人： Donald E. Gregonis , Robert L. Stephen , Dennis L. Coleman , Stephen K. Hunter , Barry K. Hanover , Jeffrey J. Harrow
IPC分类号： A61M39/02 , A61M25/00
CPC分类号： A61M39/0208
摘要： The present invention is directed to a subcutaneous peritoneal injection catheter apparatus and methods which minimizes catheter obstruction during use. The apparatus includes a receiving chamber or reservoir having a relatively small internal volume while employing a penetrable membrane and relatively enlarged target surface area. The reservoir is interconnected with the peritoneal cavity by a hollow stem. The penetrable membrane accommodates a hollow needle being inserted into the receiving reservoir and is configurated with a dome-like profile so that the membrane may also be depressed to expel insulin from the receiving reservoir into the peritoneal cavity in a direction generally toward the mesenteric peritoneal membrane.The portion of the apparatus which is in the peritoneal cavity is preferably constructed of, or coated with, a material which is capable of minimizing the adhesion of cells and the growth of bacteria on that portion of the apparatus. In a presently preferred embodiment of the subcutaneous peritoneal injection catheter, the portion of the catheter to be within the peritoneal cavity is constructed of a polyurethane material, and this polyurethane material is then coated with a solution of polyurethane and poly(ethylene glycol) in a suitable solvent.
摘要翻译：本发明涉及皮下腹膜内注射导管装置和使用过程中导尿管阻塞最小化的方法。该装置包括具有相对小的内部体积的接收室或容器，同时使用可穿透的膜和相对扩大的目标表面积。储存器通过中空茎与腹膜腔相互连接。可穿透的膜容纳插入接收容器中的中空针，并且被配置成具有圆顶状轮廓，使得膜也可以被压下，以将胰岛素从接收储器排出到通常朝向肠系膜腹膜的方向进入腹膜腔。位于腹膜腔中的装置的部分优选由能够最小化细胞粘附和细菌生长在该装置的该部分上的材料构成或涂覆。在皮下腹膜注射导管的当前优选实施例中，导管内部位于腹膜腔内的部分由聚氨酯材料构成，然后将该聚氨酯材料用聚氨酯和聚（乙二醇）溶液涂覆在合适的溶剂。

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