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1. 发明授权

US5807984A Oligopeptides, the preparation and use thereof 失效
标题翻译：寡肽，其制备和用途
公开(公告)号：US5807984A
公开(公告)日：1998-09-15
申请号：US554897
申请日：1995-11-09
申请人： Andreas Kling , Bernd Janssen , Wilhelm Amberg , Andreas Haupt , Kurt Ritter , Ernst Buschmann , Harald Bernard , Stefan Muller , Thomas Zierke , Teresa Barlozzari , Monika de Arruda , Simon Robinson
发明人： Andreas Kling , Bernd Janssen , Wilhelm Amberg , Andreas Haupt , Kurt Ritter , Ernst Buschmann , Harald Bernard , Stefan Muller , Thomas Zierke , Teresa Barlozzari , Monika de Arruda , Simon Robinson
IPC分类号： A61K38/00 , A61K31/00 , C07K7/06 , A61K38/03
CPC分类号： C07K7/06 , A61K38/00
摘要： Novel peptides of the formula A--B--D--E--F--L, wherein A, B, D, E, F, and L have the meanings stated in the specification, and their preparation are disclosed. The novel compounds are suitable for controlling diseases.
摘要翻译：式A-B-D-E-F-L的新肽，其中A，B，D，E，F和L具有说明书中所述的含义，并且公开了它们的制备。新型化合物适用于控制疾病。

2. 发明申请

US20090052532A1 AUTOMATICALLY IDENTIFYING EDGES OF MOVING OBJECTS 审中-公开
标题翻译：自动识别移动物体的边缘
公开(公告)号：US20090052532A1
公开(公告)日：2009-02-26
申请号：US11844725
申请日：2007-08-24
申请人： Simon Robinson
发明人： Simon Robinson
IPC分类号： H04N7/26
CPC分类号： H04N19/14 , G06T3/4007 , H04N7/014 , H04N7/0142 , H04N19/553
摘要： The edge identification system receives a pair of images from which an in-between image is to be created. The edge identification system calculates two vector fields: one to warp the second image onto the first, and the other to warp the first image onto the second. The two vector fields are typically symmetric; however, the fields are not symmetric along the edge of an object (e.g., the foreground) that is moving differently than the layer behind it (e.g., the background). This type of movement creates occlusions in which an object that was visible in one image will not be visible in the other image and vice versa. The edge identification system uses these areas to automatically identify the edges of moving objects. Thus, the edge identification system can identify the edges of objects without requiring the user to provide a matte or other manual assistance.
摘要翻译：边缘识别系统接收将要创建中间图像的一对图像。边缘识别系统计算两个矢量场：一个用于将第二图像扭曲到第一图像上，另一个将第一图像扭曲到第二图像上。两个矢量场通常是对称的; 然而，沿着与其背后的层（例如，背景）不同的物体（例如，前景）的边缘，这些场不是对称的。这种类型的移动会产生遮挡，其中在一个图像中可见的对象在另一个图像中将不可见，反之亦然。边缘识别系统使用这些区域来自动识别移动物体的边缘。因此，边缘识别系统可以识别对象的边缘，而不需要用户提供哑光或其他手动辅助。

3. 发明申请

US20070014721A1 Hydrazide conjugates as imaging agents 审中-公开
标题翻译：酰肼共轭物作为成像剂
公开(公告)号：US20070014721A1
公开(公告)日：2007-01-18
申请号：US11476377
申请日：2006-06-28
申请人： Thomas Harris , Simon Robinson , Richard Cesati , Padmaja Yalamanchili
发明人： Thomas Harris , Simon Robinson , Richard Cesati , Padmaja Yalamanchili
IPC分类号： A61K51/00
CPC分类号： A61K49/085 , A61K49/0002 , A61K49/10 , A61K51/088 , C07C243/38 , C07C271/22 , C07D209/16 , C07D213/82 , C07D257/02 , C07K7/02
摘要： The present disclosure is directed to diagnostic agents. More specifically, the disclosure is directed to compounds, diagnostic agents, compositions, and kits for detecting and/or imaging and/or monitoring a pathological disorder associated with coronary plaque, carotid plaque, aortic plaque, plaque of the arterial vessel, aneurism, vasculitis, and other diseases of the arterial wall. In addition, the disclosure is directed to methods of detecting and/or imaging and/or monitoring changes in the arterial wall, including expansive and constrictive remodeling, total vessel wall area, internal lumen size, and exterior artery perimeter.
摘要翻译：本公开涉及诊断剂。更具体地，本公开涉及用于检测和/或成像和/或监测与冠状动脉斑块，颈动脉斑块，主动脉斑块，动脉血管斑块，动脉瘤，血管炎相关的病理学障碍的化合物，诊断剂，组合物和试剂盒，以及其他动脉壁疾病。此外，本公开涉及检测和/或成像和/或监测动脉壁变化的方法，包括扩张和收缩性重建，总血管壁面积，内腔尺寸和外周动脉周长。

4. 发明申请

US20050245602A1 Selective estrogen receptor modulators 有权
标题翻译：选择性雌激素受体调节剂
公开(公告)号：US20050245602A1
公开(公告)日：2005-11-03
申请号：US11152891
申请日：2005-06-15
申请人： Robert Kaltenbach , Simon Robinson , George Trainor
发明人： Robert Kaltenbach , Simon Robinson , George Trainor
IPC分类号： C07D295/08 , A61K31/085 , A61K31/18 , A61K31/192 , A61K31/195 , A61K31/24 , A61K31/27 , A61K31/277 , A61K31/352 , A61K31/381 , A61K31/429 , A61K31/4453 , A61P1/00 , A61P3/10 , A61P9/00 , A61P13/00 , A61P13/08 , A61P15/00 , A61P19/10 , A61P25/28 , A61P35/00 , A61P43/00 , C07C51/487 , C07C57/50 , C07C59/54 , C07C59/72 , C07C69/618 , C07C69/734 , C07C255/34 , C07C311/51 , C07D257/04 , C07D277/80 , C07D311/58 , C07D333/34 , A61K31/353 , C07D311/04
CPC分类号： C07D257/04 , C07C51/487 , C07C57/50 , C07C59/54 , C07C59/72 , C07C69/618 , C07C69/734 , C07C255/34 , C07C311/51 , C07C2601/10 , C07C2602/10 , C07C2602/12 , C07D277/80 , C07D311/58 , C07D333/34
摘要： The present invention provides, inter alia, triphenylethylene derivatives, such as, 3-{4-[6-(3-Methoxy-phenyl)-8,9-dihydro-7H-benzocyclohepten-5-yl]-phenyl}-acrylic acid, as selective estrogen receptor modulators. Also provided are methods for treating estrogen stimulated diseases in mammals including, but not limited to, for example, breast, uterine, ovarian, prostate and colon cancer; osteoporosis; endometriosis; uterine fibroid; Alzheimer's disease; macular degeneration; urinary incontinence; and type II diabetes, as well as, pharmaceutical compositions comprising at least one compound of the present invention.
摘要翻译：本发明特别提供三苯基乙烯衍生物，例如3- {4- [6-（3-甲氧基 - 苯基）-8,9-二氢-7H-苯并环庚烯-5-基] - 苯基} - 丙烯酸，作为选择性雌激素受体调节剂。还提供了用于治疗哺乳动物中雌激素刺激的疾病的方法，包括但不限于例如乳腺癌，子宫癌，卵巢癌，前列腺癌和结肠癌; 骨质疏松症子宫内膜异位症子宫肌瘤阿尔茨海默氏病; 黄斑变性; 尿失禁和II型糖尿病，以及包含至少一种本发明化合物的药物组合物。

5. 发明申请

US20050191739A1 Polyphenol oxidase genes from banana, lettuce, tobacco and pineapple 有权
标题翻译：来自香蕉，莴苣，烟草和菠萝的多酚氧化酶基因
公开(公告)号：US20050191739A1
公开(公告)日：2005-09-01
申请号：US10619646
申请日：2003-07-15
申请人： Simon Robinson
发明人： Simon Robinson
IPC分类号： A01H5/00 , C07H21/04 , C12N5/10 , C12N9/02 , C12N15/09 , C12N15/53 , C12N15/82 , C12Q1/68
CPC分类号： C12N9/0059 , C12N9/0057 , C12N15/8241 , C12N15/8243 , C12N15/825 , C12Y110/03001
摘要： The present invention provides genetic sequences encoding polyphenol oxidase enzymes of lettuce, banana, tobacco and pineapple plants, and recombinant vectors comprising same, and methods of identifying related sequences using said nucleic acid molecules. The invention further provides methods of modifying PPO expression in plants using the inventive nucleic acid molecules.
摘要翻译：本发明提供编码莴苣，香蕉，烟草和菠萝植物的多酚氧化酶的遗传序列，以及包含其的重组载体，以及使用所述核酸分子鉴定相关序列的方法。本发明还提供了使用本发明的核酸分子修饰植物中PPO表达的方法。

6. 发明公开

US20230292791A1 FEED SUPPLEMENT AND EXTRACT 审中-公开
公开(公告)号：US20230292791A1
公开(公告)日：2023-09-21
申请号：US18021253
申请日：2021-08-25
申请人： Simon Robinson
发明人： Simon Robinson
IPC分类号： A23K10/30 , A23K30/12 , A23K50/10
CPC分类号： A23K10/30 , A23K30/12 , A23K50/10
摘要： A method of making a product from grass that includes carrying out steps A to D in order, where: Step A is cutting the grass to a length of between 35 mm to 150 mm resulting in cut grass with at least 90% leaf and little to no dead plant material; Step B is drying of the cut grass to produce dry grass; Step C is collecting and transferring the dry grass to at least one first container, removing excess air and then sealing the at least one first container; and Step D is aging the dry grass in the at least one first containers in a cool dark place for a primary period of time to produce a dry product.

7. 发明申请

US20090051679A1 LOCAL MOTION ESTIMATION USING FOUR-CORNER TRANSFORMS 审中-公开
标题翻译：使用四角变换的局部运动估计
公开(公告)号：US20090051679A1
公开(公告)日：2009-02-26
申请号：US11844716
申请日：2007-08-24
申请人： Simon Robinson
发明人： Simon Robinson
IPC分类号： G06F17/00
CPC分类号： G06T7/246
摘要： A four-corner motion system for precisely modeling local motion is provided. The four-corner motion system provides a motion estimation technique that uses a four-corner transform to describe planar motion. The four-corner motion system produces a motion field that describes the motion of each block in a reference frame at the four-corner level. Thus, the four-corner motion system provides more precise modeling of local motion.
摘要翻译：提供了一种用于精确建模局部运动的四角运动系统。四角运动系统提供了使用四角变换来描述平面运动的运动估计技术。四角运动系统产生一个运动场，描述四角水平参考系中每个块的运动。因此，四角运动系统提供了更精确的局部运动建模。

8. 发明申请

US20080112884A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING 有权
标题翻译：对比剂用于心肌灌注成像
公开(公告)号：US20080112884A1
公开(公告)日：2008-05-15
申请号：US12014161
申请日：2008-01-15
申请人： DAVID CASEBIER , Simon Robinson , Ajay Purohit , Heike Radeke , Michael Azure , Douglas Dischino
发明人： DAVID CASEBIER , Simon Robinson , Ajay Purohit , Heike Radeke , Michael Azure , Douglas Dischino
IPC分类号： A61K51/00 , A61K49/10 , C07F13/00 , C07F5/00
CPC分类号： C07D237/16 , A61K49/00 , A61K49/0002 , A61K49/0052 , A61K49/10 , A61K49/22 , A61K51/04 , A61K51/0421 , A61K51/0453 , A61K51/0459 , C07B59/002
摘要： The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the patient using diagnostic imaging.
摘要翻译：本公开部分地涉及用于成像心肌灌注的化合物和方法，包括向患者施用包含结合MC-1的化合物和成像部分的造影剂，以及使用诊断成像扫描患者。

9. 发明申请

US20050267183A1 Selective estrogen receptor modulators 有权
标题翻译：选择性雌激素受体调节剂
公开(公告)号：US20050267183A1
公开(公告)日：2005-12-01
申请号：US11152888
申请日：2005-06-15
申请人： Robert Kaltenbach , Simon Robinson , George Trainor
发明人： Robert Kaltenbach , Simon Robinson , George Trainor
IPC分类号： C07D295/08 , A61K31/085 , A61K31/18 , A61K31/192 , A61K31/195 , A61K31/24 , A61K31/27 , A61K31/277 , A61K31/352 , A61K31/381 , A61K31/429 , A61K31/4453 , A61P1/00 , A61P3/10 , A61P9/00 , A61P13/00 , A61P13/08 , A61P15/00 , A61P19/10 , A61P25/28 , A61P35/00 , A61P43/00 , C07C51/487 , C07C57/50 , C07C59/54 , C07C59/72 , C07C69/618 , C07C69/734 , C07C255/34 , C07C311/51 , C07D257/04 , C07D277/80 , C07D311/58 , C07D333/34 , A61K31/41 , C07D257/02
CPC分类号： C07D257/04 , C07C51/487 , C07C57/50 , C07C59/54 , C07C59/72 , C07C69/618 , C07C69/734 , C07C255/34 , C07C311/51 , C07C2601/10 , C07C2602/10 , C07C2602/12 , C07D277/80 , C07D311/58 , C07D333/34
摘要： The present invention provides, inter alia, triphenylethylene derivatives, such as, 5-{2-[4-(1,2-Diphenyl-but-1-enyl)-phenyl]-vinyl}-1H-tetrazole, as selective estrogen receptor modulators. Also provided are methods for treating estrogen stimulated diseases in mammals including, but not limited to, for example, breast, uterine, ovarian, prostate and colon cancer; osteoporosis; endometriosis; uterine fibroid; Alzheimer's disease; macular degeneration; urinary incontinence; and type II diabetes, as well as, pharmaceutical compositions comprising at least one compound of the present invention.
摘要翻译：本发明特别提供三苯基乙烯衍生物，例如5- {2- [4-（1,2-二苯基 - 丁-1-烯基） - 苯基] - 乙烯基} -1H-四唑，作为选择性雌激素受体调节剂。还提供了用于治疗哺乳动物中雌激素刺激的疾病的方法，包括但不限于例如乳腺癌，子宫癌，卵巢癌，前列腺癌和结肠癌; 骨质疏松症子宫内膜异位症子宫肌瘤阿尔茨海默氏病; 黄斑变性; 尿失禁和II型糖尿病，以及包含至少一种本发明化合物的药物组合物。

10. 发明申请

US20050191238A1 Contrast agents for myocardial perfusion imaging 有权
公开(公告)号：US20050191238A1
公开(公告)日：2005-09-01
申请号：US11055498
申请日：2005-02-10
申请人： David Casebier , Simon Robinson , Ajay Purohit , Heike Radeke , Michael Azure , Douglas Dischino
发明人： David Casebier , Simon Robinson , Ajay Purohit , Heike Radeke , Michael Azure , Douglas Dischino
IPC分类号： A61K49/00 , A61K51/00
CPC分类号： C07D237/16 , A61K49/00 , A61K49/0002 , A61K49/0052 , A61K49/10 , A61K49/22 , A61K51/04 , A61K51/0421 , A61K51/0453 , A61K51/0459 , C07B59/002
摘要： The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the patient using diagnostic imaging.

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