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1. 发明申请

US20050009158A1 Process for enzymatically resolving an enantiomeric mixture of alpha-hydroxy acids 审中-公开
标题翻译：酶解分解α-羟基酸的对映体混合物的方法
公开(公告)号：US20050009158A1
公开(公告)日：2005-01-13
申请号：US10795790
申请日：2004-03-08
申请人： Arindam Roy , Shubhender Kapila , Paul Nam , Virgil Flanigan , Stephen Lorbert , Charles Schasteen
发明人： Arindam Roy , Shubhender Kapila , Paul Nam , Virgil Flanigan , Stephen Lorbert , Charles Schasteen
IPC分类号： A23K1/16 , A23K1/18 , C12P7/42 , C12P41/00
CPC分类号： C12P7/42 , A23K20/105 , A23K20/147 , A23K50/10 , A23K50/30 , A23K50/75 , C12P41/005
摘要： The present invention relates to a process for resolving an enantiomeric mixture of a-hydroxy acids or derivatives thereof through esterification and subsequent enzymatic hydrolysis of the α-hydroxy acids or derivatives. The present invention also relates to purified α-hydroxy acids or derivatives and methods of use thereof.
摘要翻译：本发明涉及通过酯化和随后的α-羟基酸或衍生物的酶水解来拆分α-羟基酸或其衍生物的对映体混合物的方法。本发明还涉及纯化的α-羟基酸或其衍生物及其使用方法。

2. 发明申请

US20130256113A1 MODULAR PLANT FOR PERFORMING CONVERSION PROCESSES OF CARBONACEOUS MATRICES 审中-公开
标题翻译：用于实施碳化物转化过程的模块化设备
公开(公告)号：US20130256113A1
公开(公告)日：2013-10-03
申请号：US13992198
申请日：2011-12-22
申请人： Vander Tumiatti , Michela Tumiatti , Shubhender Kapila , Francesco Lenzi , Carlo Roggero
发明人： Vander Tumiatti , Michela Tumiatti , Shubhender Kapila , Francesco Lenzi , Carlo Roggero
IPC分类号： C10B1/10
CPC分类号： C10B1/10 , C10B47/30 , C10B49/14 , C10B49/16 , C10B53/02 , C10B53/07 , C10C5/00 , C10G1/02 , C10G2/30 , C10G2300/1007 , C10G2300/1011 , C10G2300/1014 , C10G2300/1022 , C10L9/083 , F23G5/20 , F23G2203/209 , F23G2900/50801 , F27B7/02 , F27B7/3205 , F27B7/33 , Y02E20/12 , Y02E50/14 , Y02E50/15 , Y02E50/32 , Y02P20/143 , Y02P30/20
摘要： A modular plant, including at least one basic module is suitable for converting carbonaceous matrices (6) into fuel or useful products with no adverse environmental impact. The modular plant includes a rotary reactor (9) with a rotating drive mechanism (22) and a fixed stationary body (1). The inclination of the reactor (9) with rotating central longitudinal axis can vary from 0° to 45° with respect to horizontal. The reactor has a substantially cylindrical central body closed at a first entry end with a stationary fixed head (8), and at the exit end with a head fixed to the rotary reactor (9). The inlet end (8) contains one inlet (7) for the introduction of the carbonaceous matrix (6) into the rotary reactor and the other inlet (5) for introducing thermally conductive carriers (4). The rotary reactor (9) lacks internal components which provide rotation motion relative to the cylindrical body. The fixed housing body (1) enclosing the rotary reactor (9) seals the reactor and maintains the integrity of the reactor atmosphere. The housing has openings for the passage of the inlets and an exit for the converted carbonaceous matrix (17, 19) and the thermally conductive carrier (4).
摘要翻译：包括至少一个基本模块的模块化设备适用于将碳质基质（6）转化为燃料或有用的产品，而不会对环境产生不利影响。模块化设备包括具有旋转驱动机构（22）和固定固定体（1）的旋转反应器（9）。具有旋转中心纵向轴线的反应器（9）的倾斜度可相对于水平度在0°至45°之间变化。反应器具有在具有固定固定头（8）的第一入口处封闭的基本上圆柱形的中心体，并且在出口端具有固定到旋转反应器（9）的头部。入口端（8）包含用于将碳质基质（6）引入旋转反应器的入口（7）和用于引入导热载体（4）的另一入口（5）。旋转反应器（9）缺少相对于圆柱体提供旋转运动的内部部件。封闭旋转反应器（9）的固定壳体（1）密封反应器并保持反应堆气氛的完整性。壳体具有用于入口通过的开口和用于转化的碳质基质（17,19）和导热载体（4）的出口。

3. 发明申请

US20050260138A1 Producton and use of a gaseous vapor disinfectant 审中-公开
标题翻译：产生和使用气态蒸气消毒剂
公开(公告)号：US20050260138A1
公开(公告)日：2005-11-24
申请号：US10851780
申请日：2004-05-21
申请人： Virgil Flanigan , Shubhender Kapila , Robert Bolla
发明人： Virgil Flanigan , Shubhender Kapila , Robert Bolla
IPC分类号： A01M13/00 , A01N37/02 , A01N37/04 , A61K31/22 , A61L2/20 , A61L2/22 , A61L9/02 , A61L9/03 , A61L9/04
CPC分类号： A61L2/22 , A01M13/00 , A01N37/02 , A01N37/04 , A61K31/22 , A61L2/20 , A61L9/02 , A61L9/03 , Y02A50/393 , Y02A50/475 , Y02A50/478 , Y02A50/481 , A01N2300/00
摘要： Smoke or vapor generating system disperses an airborne biocidal oil, such as methyl soyate, to decontaminate and area or object. The airborne forms of methyl soyate are have broad spectrum efficacy against a wide variety of microscopic pathogens including viruses, bacteria and fungi.
摘要翻译：烟雾或蒸汽发生系统将空气中的杀生物油（例如大豆油甲基酯）分散到去污和面积或物体上。甲基大豆油的空气传播形式对各种微观病原体（包括病毒，细菌和真菌）具有广谱效力。

4. 发明授权

US06939693B2 Enantioselective oligomerization of α-hydroxy carboxylic acids and α-amino acids 失效
标题翻译： α-羟基羧酸和α-氨基酸的对映选择性低聚
公开(公告)号：US06939693B2
公开(公告)日：2005-09-06
申请号：US10136974
申请日：2002-05-02
申请人： Stephen J. Lorbert , Charles S. Schasteen , Paul K. S. Nam , Daniel Forciniti , Mathur P. Rajesh , Shubhender Kapila
发明人： Stephen J. Lorbert , Charles S. Schasteen , Paul K. S. Nam , Daniel Forciniti , Mathur P. Rajesh , Shubhender Kapila
IPC分类号： A23K1/16 , A23K1/165 , A23K1/18 , C07K2/00 , C07K7/06 , C12P21/00 , C12P13/04
CPC分类号： C07K7/06 , A23K20/105 , A23K20/142 , A23K20/147 , A23K20/189 , A23K50/00 , A23K50/10 , A23K50/80 , C07K2/00 , C12P21/00
摘要： An enzymatic synthesis and composition of oligomers and co-oligomers comprised of α-hydroxy carboxylic acids and α-amino acids or peptides is disclosed. In a preferred embodiment, a α-hydroxy carboxylic acid with a specific chiral configuration is linked by an amide linkage to a α-amino acid specific with a specific chiral configuration or linked by an amide linkage to a peptide made up of α-amino acid monomers having identical chiral configurations. Proteolytic enzymes catalyze oligomerization of the α-hydroxy carboxylic acid and α-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to animals such as ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen and other animals such as swine, poultry and aquatic animals.
摘要翻译：公开了由α-羟基羧酸和α-氨基酸或肽组成的低聚物和共低聚物的酶合成和组合物。在一个优选的实施方案中，具有特定手性构型的α-羟基羧酸通过酰胺键与具有特异性手性构型特异性的α-氨基酸连接，或通过酰胺键连接到由α-氨基酸组成的肽具有相同手性构型的单体。蛋白水解酶催化α-羟基羧酸和α-氨基酸的低聚。低聚度的程度和分布根据所使用的不同反应混合物的类型和浓度以及允许的反应时间长短而变化。所得到的低聚物可以提供给诸如反刍动物的动物作为生物可利用氨基酸补充剂，其对瘤胃和其他动物如猪，家禽和水生动物的降解具有抗性。

5. 发明申请

US20090321534A1 Aerosol or gaseous decontaminant generator and application thereof 审中-公开
标题翻译：气溶胶或气体净化发生器及其应用
公开(公告)号：US20090321534A1
公开(公告)日：2009-12-31
申请号：US11292720
申请日：2005-12-02
申请人： Virgil Flanigan , Shubhender Kapila
发明人： Virgil Flanigan , Shubhender Kapila
IPC分类号： B05B1/24
CPC分类号： A61L9/03
摘要： Disclosed is a generator for the production of an oil based aerosol or a gaseous vapor, which can be used for decontamination of an area, by heating petroleum fuels, plant oils, animal fat derived oils, or light mineral oils in the temperature range of from 250° C. to 800° C., ±5° C. The generator is capable of producing oil particles of a diameter of about 0.04 microns to 3 microns, the most preferred diameter being of about 0.15 microns to 1.5 microns. A condensing trap distal to a concentric tubular oven, which is used to heat the oil, removes non vaporized oil particles from the smoke to produce a gaseous vapor having the advantage of leaving no residue in the area following the decontamination process. An additional filter apparatus controls the size of the oil particles released into the environment.
摘要翻译：公开了一种用于生产油基气溶胶或气体蒸汽的发生器，其可以用于对区域进行去污，通过加热石油燃料，植物油，动物脂肪衍生的油或轻质矿物油，其温度范围为 250℃至800℃，±5℃。发生器能够生产直径为约0.04微米至3微米的油颗粒，最优选的直径为约0.15微米至1.5微米。远离用于加热油的同心管状炉的冷凝阱从烟中除去未汽化的油颗粒，产生气体蒸汽，其具有在除污处理之后的区域中不留下残留物的优点。附加的过滤装置控制释放到环境中的油颗粒的尺寸。

6. 发明申请

US20090298935A1 Production And Use Of A Gaseous Vapor Disinfectant 审中-公开
标题翻译：生产和使用气体蒸气消毒剂
公开(公告)号：US20090298935A1
公开(公告)日：2009-12-03
申请号：US12410351
申请日：2009-03-24
申请人： Virgil Flanigan , Shubhender Kapila
发明人： Virgil Flanigan , Shubhender Kapila
IPC分类号： A01N37/00 , A01P1/00
CPC分类号： A61L2/22 , A01M13/00 , A01N37/02 , A01N37/04 , A61K31/22 , A61L2/20 , A61L9/02 , A61L9/03 , Y02A50/393 , Y02A50/475 , Y02A50/478 , Y02A50/481 , A01N2300/00
摘要： Smoke or vapor generating system disperses an airborne biocidal oil, such as methyl soyate, to decontaminate and area or object. The airborne forms of methyl soyate are have broad spectrum efficacy against a wide variety of microscopic pathogens including viruses, bacteria and fungi.
摘要翻译：烟雾或蒸汽发生系统将空气中的杀生物油（例如大豆油甲基酯）分散到去污和面积或物体上。甲基大豆油的空气传播形式对各种微观病原体（包括病毒，细菌和真菌）具有广谱效力。

7. 发明授权

US6100440A Process for the decontamination and treatment with oxidative counterflow of a liquid, gaseous or solid matrix 失效
标题翻译：用于液体，气态或固体基质的氧化反流的去污和处理方法
公开(公告)号：US6100440A
公开(公告)日：2000-08-08
申请号：US29129
申请日：1998-06-08
申请人： Wander Tumiatti , Shubhender Kapila
发明人： Wander Tumiatti , Shubhender Kapila
IPC分类号： A62D3/176 , A62D3/38 , A62D101/20 , A62D101/22 , A62D101/28 , A62D3/00
CPC分类号： A62D3/38 , A62D3/176 , A62D2101/20 , A62D2101/22 , A62D2101/28 , A62D2203/02
摘要： The process includes the steps of filling a first reactor (10) with a particulate support (22) comprising a solid matrix to be decontaminated and treated, or a matrix impregnated by a liquid or gaseous matrix to be decontaminated and treated; and introducing at one end (23) of the reactor (10) an oxidative flow triggering a thermoxidation reaction at the opposite end (24) in such a manner that a mobile flame front (26) is generated in the direction opposite (28) to the oxidative flow. The flame front has a temperature of at least 1200.degree. C. so as to substantially decompose or destroy contaminants, undesired substances and compounds initially present in the matrix. Preferably, prior to triggering the thermoxidation reaction, the particulate support (22) is mixed and/or treated with a decontaminating reagent.
摘要翻译： PCT No.PCT / EP96 / 03682 Sec。 371日期1998年6月8日第 102（e）日期1998年6月8日PCT 1996年8月21日PCT公布。公开号WO97 / 07858 日期1997年3月6日该方法包括以下步骤：向第一反应器（10）填充包含待净化和处理的固体基质的颗粒载体（22），或由待去污和处理的液体或气体基质浸渍的基质 ; 以及在反应器（10）的一端（23）处引入在相对端（24）处引发热氧化反应的氧化流，使得在相反（28）到（...）的方向上产生可移动火焰前沿（26）氧化流。火焰前端具有至少1200℃的温度，以便基本上分解或破坏最初存在于基质中的污染物，不需要的物质和化合物。优选地，在触发热氧化反应之前，颗粒状载体（22）与去污试剂混合和/或处理。

8. 发明授权

US09075038B2 Integrated methods for corrosivity, ageing and fingerprinting determination, as well as diagnosis, decontamination, depolarisation and detoxification of oils 有权
标题翻译：腐蚀性，老化和指纹测定的综合方法，以及油的诊断，去污，去极化和解毒
公开(公告)号：US09075038B2
公开(公告)日：2015-07-07
申请号：US13130156
申请日：2009-12-16
申请人： Vander Tumiatti , Shubhender Kapila , Carlo Maria Roggero , Stefano Di Carlo , Michela Tumiatti , Riccardo Maina , Kyle R. Anderson
发明人： Vander Tumiatti , Shubhender Kapila , Carlo Maria Roggero , Stefano Di Carlo , Michela Tumiatti , Riccardo Maina , Kyle R. Anderson
IPC分类号： G01N33/26 , G01N33/28
CPC分类号： G01N33/287 , G01N33/2876 , Y10T436/18
摘要： The methods of the invention are aimed toward the determination of corrosivity, ageing, fingerprinting and contaminants, as well as the functional diagnosis, decontamination, depolarization and detoxification of oils and technical fluids, such as mineral insulating, natural and/or synthetic esters, lubricants, hydraulic fluids, diathermic fluids and technical fluids in general, used in apparatuses and equipment, such as electric transformers, reactors, bushings, switches and turbines, for the generation, transmission, distribution and use of power.
摘要翻译：本发明的方法旨在确定腐蚀性，老化，指纹和污染物，以及油和工业液体如矿物绝缘，天然和/或合成酯，润滑剂的功能诊断，去污，去极化和解毒液压流体，透热流体和技术流体，用于诸如电力变压器，电抗器，衬套，开关和涡轮机的设备和设备中，用于发电，传输，分配和使用电力。

9. 发明申请

US20070196448A1 Enantioselective oligomerization of alpha-hydroxy carboxylic acids and alpha-amino acids 审中-公开
公开(公告)号：US20070196448A1
公开(公告)日：2007-08-23
申请号：US11219558
申请日：2005-09-02
申请人： Stephen Lorbert , Charles Schasteen , Paul Nam , Daniel Forciniti , Mathur Rajesh , Shubhender Kapila
发明人： Stephen Lorbert , Charles Schasteen , Paul Nam , Daniel Forciniti , Mathur Rajesh , Shubhender Kapila
IPC分类号： A23K1/165 , C12P21/06 , C12P7/62
CPC分类号： C07K7/06 , A23K20/105 , A23K20/142 , A23K20/147 , A23K20/189 , A23K50/00 , A23K50/10 , A23K50/80 , C07K2/00 , C12P21/00
摘要： An enzymatic synthesis and composition of oligomers and co-oligomers comprised of α-hydroxy carboxylic acids and α-amino acids or peptides is disclosed. In a preferred embodiment, a α-hydroxy carboxylic acid with a specific chiral configuration is linked by an amide linkage to a α-amino acid specific with a specific chiral configuration or linked by an amide linkage to a peptide made up of α-amino acid monomers having identical chiral configurations. Proteolytic enzymes catalyze oligomerization of the α-hydroxy carboxylic acid and α-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to animals such as ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen and other animals such as swine, poultry and aquatic animals.

10. 发明授权

US06605590B1 Oligomers and oligomeric segments of alpha-hydroxy carboxylic acids and alpha-amino acids 失效
标题翻译： α-羟基羧酸和α-氨基酸的低聚物和低聚链段
公开(公告)号：US06605590B1
公开(公告)日：2003-08-12
申请号：US09699946
申请日：2000-10-30
申请人： Stephen J. Lorbert , Charles S. Schasteen , Paul K. S. Nam , Daniel Forciniti , Mathur P. Rajesh , Shubhender Kapila
发明人： Stephen J. Lorbert , Charles S. Schasteen , Paul K. S. Nam , Daniel Forciniti , Mathur P. Rajesh , Shubhender Kapila
IPC分类号： A23L1305
CPC分类号： C07K7/06 , C12P21/00
摘要： An enzymatic synthesis and composition of &agr;-hydroxy carboxylic acid and &agr;-amino acid or peptide co-oligomers is disclosed wherein a residue of the &agr;-hydroxy carboxylic acid is linked to a residue of the &agr;-amino acid or peptide by an amide linkage. Proteolytic enzyme papain catalyzes co-oligomerization of the &agr;-hydroxy carboxylic acid and &agr;-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen.
摘要翻译：公开了α-羟基羧酸和α-氨基酸或肽共低聚物的酶合成和组合物，其中α-羟基羧酸的残基通过酰胺键连接到α-氨基酸或肽的残基。蛋白水解酶木瓜蛋白酶催化α-羟基羧酸和α-氨基酸的共低聚。低聚度的程度和分布根据所使用的不同反应混合物的类型和浓度以及允许的反应时间长短而变化。所得到的寡聚物可以提供给反刍动物作为抗瘤胃降解的生物可利用氨基酸补充剂。

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