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1. 发明授权

US5525933A Semiconductor integrated circuit 失效
标题翻译：半导体集成电路
公开(公告)号：US5525933A
公开(公告)日：1996-06-11
申请号：US392119
申请日：1995-02-22
申请人： Shigeru Matsuki , Kazuhiro Sugita
发明人： Shigeru Matsuki , Kazuhiro Sugita
IPC分类号： H03K19/003 , H03K5/08 , H03K17/16 , H03K19/0944
CPC分类号： H03K19/00315
摘要： A semiconductor integrated circuit comprises a signal input terminal, a power supply voltage terminal to which a power voltage is applied, a reference voltage terminal to which a ground voltage is applied, a first PMOS transistor having a drain, a gate connected to the signal input terminal, and a source connected to the power supply voltage terminal, a second PMOS transistor having a gate and a drain being mutually connected to each other, and a source connected to the drain of the first transistor, a third PMOS transistor having a gate connected to the drain of the second transistor, a source connected to the power supply potential terminal, and a drain connected to the drain of the first transistor, an NMOS transistor having a gate connected to the power supply voltage terminal, a drain connected to the drain of the second PMOS transistor, and a source connected to the reference voltage terminal, an internal circuit connected to the drain of the NMOS transistor, a first overvoltage absorption element, connected between the reference voltage terminal and the signal input terminal, for absorbing an overvoltage applied to the signal input terminal, and a second overvoltage absorption element, connected between the signal input terminal and the power supply voltage terminal, for absorbing an overvoltage applied to the signal input terminal.
摘要翻译：半导体集成电路包括信号输入端子，施加电源电压的电源电压端子，施加接地电压的基准电压端子，具有漏极的第一PMOS晶体管，连接到信号输入端的栅极端子和连接到电源电压端子的源极，具有彼此相互连接的栅极和漏极的第二PMOS晶体管，以及连接到第一晶体管的漏极的源极，具有栅极连接的第三PMOS晶体管到第二晶体管的漏极，连接到电源电位端的源极和连接到第一晶体管的漏极的漏极，具有连接到电源电压端子的栅极的NMOS晶体管，连接到漏极的漏极的第二PMOS晶体管和连接到参考电压端子的源极，连接到NMOS晶体管的漏极的内部电路，第一过电压吸收元件，连接在参考电压端子和信号输入端子之间，用于吸收施加到信号输入端子的过电压，以及连接在信号输入端子和电源电压端子之间的用于吸收过电压的第二过电压吸收元件应用于信号输入端子。

2. 发明授权

US4313934A Physiologically active polysaccharides, production and uses thereof 失效
标题翻译：生理活性多糖，其生产和用途
公开(公告)号：US4313934A
公开(公告)日：1982-02-02
申请号：US141232
申请日：1980-04-17
申请人： Kumpei Kitamura , Shigeru Matsuki , Kozo Tanabe
发明人： Kumpei Kitamura , Shigeru Matsuki , Kozo Tanabe
IPC分类号： A61K36/064 , A61K36/07 , A61K38/00 , C07K14/395 , C12P1/02 , C12P21/00 , A61K39/00 , A61K37/00 , C07G7/00
CPC分类号： C12P21/005 , A61K36/064 , A61K36/07 , C07K14/395 , C12P1/02 , A61K38/00 , Y10S514/889
摘要： A physiologically active polysaccharide is prepared by treating autolysis-insoluble matters of yeasts of Saccharomyces with a yeast cell wall-lytic enzyme and obtaining a water-soluble physiologically active substance in the resulting solution-fraction. The novel polysaccharide possesses specific physical and chemical properties, and provides a chemotherapeutic agent such as a carcinostatic agent which can be used in the treatment of implanted tumors in mice and rats and an interferon inducer.
摘要翻译：通过用酵母细胞裂解酶处理酵母菌的自溶不溶性物质并在所得溶液馏分中获得水溶性生理活性物质来制备生理活性多糖。该新型多糖具有特定的物理和化学性质，并提供可用于治疗小鼠和大鼠和干扰素诱导剂中植入的肿瘤的化学治疗剂，例如制癌剂。

3. 发明授权

US5798274A Method for selecting monoclonal antibodies for human G-CSF permitting low-level detection in human fluids 失效
标题翻译：选择用于人G-CSF的单克隆抗体的方法，其允许人体液体中的低水平检测
公开(公告)号：US5798274A
公开(公告)日：1998-08-25
申请号：US477328
申请日：1995-06-07
申请人： Takanori Ichikawa , Tomoaki Kuwaki , Shigeru Matsuki , Katsumi Tachibana
发明人： Takanori Ichikawa , Tomoaki Kuwaki , Shigeru Matsuki , Katsumi Tachibana
IPC分类号： C12P21/08 , C07K16/24 , C12R1/91 , G01N33/53 , G01N33/577 , G01N33/68 , G01N33/531 , G01N33/543
CPC分类号： G01N33/6863 , C07K16/243 , G01N2333/535 , G01N2500/00
摘要： The present invention relates to a high affinity monoclonal antibody for human G-CSF and to an enzyme immunoassay using said antibody. Specifically, the practice of the invention permits one skilled in the art to obtain monoclonal antibodies with the characteristics necessary to permit low-level detection of G-CSF in plasma of equal to or less than 0.5 pg/ml in an immunoassay without interference in human fluids.
摘要翻译：本发明涉及用于人G-CSF的高亲和力单克隆抗体和使用所述抗体的酶免疫测定。具体而言，本发明的实践允许本领域技术人员获得具有必要特性的单克隆抗体，其允许在免疫测定中使血浆中G-CSF在血浆中低于或等于0.5pg / ml的低水平检测，而不会干扰人流体。

4. 发明授权

US5468846A Monoclonal antibodies and method for the determination of human G-CSF 失效
标题翻译：用于测定人G-CSF的单克隆抗体和方法
公开(公告)号：US5468846A
公开(公告)日：1995-11-21
申请号：US199493
申请日：1994-02-22
申请人： Takanori Ichikawa , Tomoaki Kuwaki , Shigeru Matsuki , Katsumi Tachibana
发明人： Takanori Ichikawa , Tomoaki Kuwaki , Shigeru Matsuki , Katsumi Tachibana
IPC分类号： C12P21/08 , C07K16/24 , C12R1/91 , G01N33/53 , G01N33/577 , G01N33/68 , A61K35/14 , C12N5/20
CPC分类号： G01N33/6863 , C07K16/243 , G01N2333/535 , G01N2500/00
摘要： The present invention relates to a high affinity monoclonal antibody and to an enzyme immunoassay of human G-CSF using the antibody.The trace amount of human G-CSF in samples such as body fluids from patients with hematological disorders can be measured without interference in the body fluids. For example, the measurable human G-CSF concentration in plasma is 0.5 pg/ml in minimum.
摘要翻译：本发明涉及高亲和性单克隆抗体和使用该抗体的人G-CSF的酶免疫测定。可以在不影响体液的情况下测量样品中痕量的人类G-CSF，例如来自患有血液疾病的患者的体液。例如，血浆中可测量的人G-CSF浓度最小为0.5pg / ml。

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