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    • 4. 发明授权
    • Selection and isolation apparatus for use with ECG device
    • 选择和隔离装置用于心电图设备
    • US4742831A
    • 1988-05-10
    • US800478
    • 1985-11-21
    • Sergiu Silvian
    • Sergiu Silvian
    • A61B5/0428A61B5/04
    • A61B5/04282Y10S128/902Y10S128/908
    • Isolation circuitry for use with diagnostic ECG devices provides high common mode rejection and low leakage current using optoisolators in conjunction with an isolating operational amplifier. A predetermined pattern of binary input signals selectively energizes, via the optoisolators, a plurality of switches interposed between electrodes positioned on a patient's skin and the isolating operational amplifier. This selection couples a predetermined combination of electrodes to the isolating operational amplifier to provide the desired ECG output. The output from the isolating operational amplifier may be coupled directly to a recording device or coupled to a circuit which processes the ECG signal before the signal is recorded.
    • 用于诊断ECG设备的隔离电路通过与隔离运算放大器结合使用光隔离器提供高共模抑制和低漏电流。 二进制输入信号的预定模式通过光隔离器选择性地激励位于患者皮肤上的电极和隔离运算放大器之间的多个开关。 该选择将预定的电极组合耦合到隔离运算放大器以提供期望的ECG输出。 来自隔离运算放大器的输出可以直接耦合到记录装置,或耦合到在记录信号之前处理ECG信号的电路。
    • 5. 发明授权
    • Bi-directional telemetry system and method for transmitting data at high transmission rate
    • 双向遥测系统和高速传输数据的方法
    • US06577898B2
    • 2003-06-10
    • US09844190
    • 2001-04-26
    • Sergiu Silvian
    • Sergiu Silvian
    • A61N136
    • A61N1/3727H04L27/365
    • A bi-directional telemetry system includes an implanted unit that allows a high-speed transfer of digital data with minimal complexity of the electronic circuitry. A corresponding external unit is capable of decoding the high-data-rate transmitted information and, in turn, communicates with the implanted unit using pulse amplitude modulation. The data transmission rate of the implanted unit to the external device is 32 kbps, a four-fold increase over conventional data transmission rates, without increasing the carrier frequency. To this end, the implanted unit using a modified implementation of the quadrature amplitude modulation (QAM) method that generates the required symbols from readily available squarewave signals. Simulated sinewaves are generated within the transmitter by an inverting amplifier stage with variable input resistance determined by a pair of switches that are ultimately controlled by 16 k and 32 k clocks in the implanted unit. Data is encoded by changing the amplitude and polarity of the simulated sinewaves. Quadrupling of the data rate is achieved by taking advantage of the orthogonality of I and Q components, whose phases are in quadrature.
    • 双向遥测系统包括植入单元,其允许以最小的电子电路的复杂性高速传输数字数据。 对应的外部单元能够对高数据速率传输的信息进行解码,并且使用脉冲幅度调制进而与植入单元进行通信。 植入单元到外部设备的数据传输速率为32kbps,比传统数据传输速率提高了四倍,而不增加载波频率。 为此,植入单元使用从容易获得的方波信号产生所需符号的正交幅度调制(QAM)方法的修改实现。 模拟的正弦波通过反相放大器级在发射机内产生,可变输入电阻由一对开关确定,最终由植入单元中的16 k和32 k时钟控制。 数据通过改变模拟正弦波的振幅和极性进行编码。 通过利用相位正交的I和Q分量的正交性来实现数据速率的四倍。
    • 6. 发明授权
    • Transformer assembly for implantable cardiac stimulation device
    • 用于植入式心脏刺激装置的变压器组件
    • US06477414B1
    • 2002-11-05
    • US09844035
    • 2001-04-26
    • Sergiu Silvian
    • Sergiu Silvian
    • A61N139
    • A61N1/3975A61N1/3981
    • The transformer assembly is coupled between a power supply and a pulse delivery circuit of the implantable cardiac stimulation device for charging a pair of defibrillation capacitors for delivering defibrillation pulses. The power transformer assembly is formed from a printed circuit board (PCB) having a set of transformer coil turns embedded therein and a transformer core mounted adjacent to the windings of the PCB. By embedding the coil of the transformer within the PCB, the transformer may be more easily integrated with other components of the stimulation device so that the overall size of the stimulation device may be reduced. Moreover, the use of a PCB helps avoid reliability problems that might otherwise occur in the fabrication, assembly and operation of the device. In one specific configuration described herein, the transformer assembly includes a primary and two secondary transformers. The primary transformer is used as a flyback transformer for charging the pair of defibrillation capacitors. The two secondary transformers are used to provide voltage for selectively switching on a set of transistors formed in an H-bridge configuration so as to apply charge stored in the capacitors in biphasic pulse waveform to the heart. The coils of the primary and secondary transformers are all embedded within a single PCB. In another configuration, only the coil of the primary transformer is embedded within the PCB. The coils of the two secondary transformers are affixed to the surface of the PCB.
    • 变压器组件耦合在电源和可植入心脏刺激装置的脉冲输送电路之间,用于对一对用于递送除颤脉冲的除颤电容器进行充电。 电力变压器组件由具有嵌入其中的一组变压器线圈圈的印刷电路板(PCB)形成,以及与PCB的绕组相邻安装的变压器芯。 通过将变压器的线圈嵌入PCB内,变压器可以更容易地与刺激装置的其他部件集成,使得可以减小刺激装置的总体尺寸。 此外,PCB的使用有助于避免在器件的制造,组装和操作中可能发生的可靠性问题。 在本文所述的一种特定配置中,变压器组件包括主变压器和两个次级变压器。 主变压器用作反激式变压器,用于对一对除颤电容器进行充电。 两个次级变压器用于提供电压,用于选择性地接通以H桥配置形成的一组晶体管,以将存储在电容器中的电荷施加到双相脉冲波形到心脏。 主变压器和次级变压器的线圈都嵌入单个PCB。 在另一种配置中,只有主变压器的线圈嵌入在PCB内。 两个次级变压器的线圈固定在PCB的表面上。
    • 8. 发明授权
    • Bidirectional telemetry apparatus and method for implantable device
    • 双向遥测装置及植入式装置的方法
    • US5562713A
    • 1996-10-08
    • US375311
    • 1995-01-18
    • Sergiu Silvian
    • Sergiu Silvian
    • A61N1/372A61N1/37
    • A61N1/37252Y10S128/903
    • An improved telemetry system for telemetering data from an implantable device such as a heart pacemaker to an external device with minimum energy consumption. The external device first sweeps its receiver across a predetermined frequency band, e.g., the fm broadcast band of 88 MHz to 108 MHz, to determine the particular frequency having the lowest ambient electromagnetic noise level, which it deems the optimum frequency for the telemetry to occur. The external device's transmitter then commands the pacemaker to telemeter a predetermined start signal at a succession of frequencies that sweep across that same frequency band, while the external device's receiver remains tuned to the optimum frequency. Eventually, the external devices receiver will receive the start signal and the external device thereupon will command the pacemaker to thereafter remain at its current frequency for the subsequent telemetry of data. Thus, the pacemaker is effectively tuned to the optimum frequency without the need for the pacemaker to incorporate an elaborate frequency synthesizer and without the need to draw excessive energy from the limited supply available so as to overcome interference at the operating frequency.
    • 一种改进的遥测系统,用于将数据从诸如心脏起搏器的可植入装置遥测到具有最小能量消耗的外部装置。 外部设备首先将其接收机扫过预定频带,例如88MHz至108MHz的fm广播频带,以确定具有最低环境电磁噪声电平的特定频率,其被认为是发生遥测的最佳频率 。 然后,外部设备的发射器命令起搏器以扫描跨相同频带的一系列频率遥测预定的起始信号,同时外部设备的接收机保持调谐到最佳频率。 最终,外部设备接收器将接收起始信号,并且外部设备随后将命令起搏器此后保持在其当前频率以用于随后的数据遥测。 因此,心脏起搏器被有效地调整到最佳频率,而不需要起搏器并入精细的频率合成器,并且不需要从有限的可用电源中抽取过多的能量,以克服在工作频率处的干扰。