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1. 发明申请

US20110101995A1 METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS 审中-公开
公开(公告)号：US20110101995A1
公开(公告)日：2011-05-05
申请号：US13004660
申请日：2011-01-11
申请人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
IPC分类号： G06F19/00 , G01R35/00
摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

2. 发明申请

US20100191087A1 SENSING SYSTEM WITH AUXILIARY DISPLAY 审中-公开
标题翻译：带辅助显示器的感应系统
公开(公告)号：US20100191087A1
公开(公告)日：2010-07-29
申请号：US12758391
申请日：2010-04-12
申请人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, JR. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
发明人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, JR. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
IPC分类号： A61B5/145
CPC分类号： A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/412 , A61B2560/0209 , A61B2560/0443 , A61B2560/0456
摘要： A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.
摘要翻译：提供了一种用于感测患者血糖数据的系统。该系统包括传感器，用户界面和可选的辅助设备。如果传感器和用户界面之间的连接是通过导线连接的，那么当导线断开时，传感器保持供电。传感器和用户界面之间的通信可能是无线的。辅助装置可以是患者监视器或其他显示器或信号装置，其显示关于由传感器收集的血糖数据的信息。传感器连接到传感器电子设备，其中包括传感器电源，电压调节器以及可选的存储器和处理器。

3. 发明授权

US06740075B2 Ambulatory medical apparatus with hand held communication device 有权
公开(公告)号：US06740075B2
公开(公告)日：2004-05-25
申请号：US09768204
申请日：2001-01-22
申请人： Ronald J. Lebel , Varaz Shahmirian , Timothy J. Starkweather , Daniel H. Villegas , David Y. Choy , Philip T. Weiss , Colin A. Chong , Peter C. Lord , Wayne A. Morgan , Paul M. Meadows
发明人： Ronald J. Lebel , Varaz Shahmirian , Timothy J. Starkweather , Daniel H. Villegas , David Y. Choy , Philip T. Weiss , Colin A. Chong , Peter C. Lord , Wayne A. Morgan , Paul M. Meadows
IPC分类号： A61K922
CPC分类号： A61M5/172 , A61B5/0002 , A61B5/14532 , A61B5/6847 , A61B2560/0209 , A61M5/14244 , A61M5/14276 , A61M5/168 , A61M5/16831 , A61M2005/14208 , A61M2205/18 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61M2207/00 , A61N1/37211 , A61N1/37247 , A61N1/37252 , A61N1/37258 , A61N1/37264 , A61N1/3727 , A61N1/37276 , A61N1/375 , G06F3/0619 , G06F3/065 , G06F3/0673 , G06F8/60 , G06F8/65 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H40/40 , Y02D10/42 , Y10S128/13 , Y10S128/903 , Y10T29/49117 , Y10T29/49826
摘要： A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.

4. 发明授权

US08602992B2 Methods and systems for detecting the hydration of sensors 有权
标题翻译：检测传感器水合的方法和系统
公开(公告)号：US08602992B2
公开(公告)日：2013-12-10
申请号：US12887465
申请日：2010-09-21
申请人： Rajiv Shah , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
发明人： Rajiv Shah , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
IPC分类号： A61B5/05 , A61B5/00
CPC分类号： G01N27/403 , A61B5/14532 , A61B5/1473 , A61B2560/0223 , A61B2562/02 , C12Q1/006 , G01N27/327 , G01N27/416
摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.
摘要翻译：传感器系统包括传感器和传感器电子设备。传感器包括多个电极。传感器电子设备包括连接检测装置，电源和延迟电路。连接检测装置确定传感器电子设备是否连接到传感器并发送连接信号。延迟电路接收连接信号，等待预设的水合时间，并且在经过预设水合时间之后将调节的电压从电源耦合到传感器中的电极。或者，传感器电子设备可以包括电检测电路和微控制器。电检测电路确定多个电极是否水合，并且如果电极是水合的则产生中断。微控制器接收中断，并将代表电压的信号传送到多个电极的电极。

5. 发明授权

US08532732B2 Methods and systems for detecting the hydration of sensors 有权
公开(公告)号：US08532732B2
公开(公告)日：2013-09-10
申请号：US12887449
申请日：2010-09-21
申请人： Rajiv Shah , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
发明人： Rajiv Shah , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
IPC分类号： A61B5/05
CPC分类号： G01N27/403 , A61B5/14532 , A61B5/1473 , A61B2560/0223 , A61B2562/02 , C12Q1/006 , G01N27/327 , G01N27/416
摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

6. 发明申请

US20120123690A1 REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD 有权
标题翻译：实时自校准传感器系统及方法
公开(公告)号：US20120123690A1
公开(公告)日：2012-05-17
申请号：US13340562
申请日：2011-12-29
申请人： LU WANG , RAJIV SHAH , WAYNE A. MORGAN , BARRY KEENAN
发明人： LU WANG , RAJIV SHAH , WAYNE A. MORGAN , BARRY KEENAN
IPC分类号： G06F19/00 , G01N27/403
CPC分类号： A61B5/1495 , A61B5/0031 , A61B5/14532 , A61B5/1468 , A61B5/1473 , A61B5/14865 , A61B2560/0223 , A61M2005/1726
摘要： A system and method for calibrating a sensor of a characteristic monitoring system in real time utilizes a self-calibration module for periodic determination of, and compensation for, the IR drop across unwanted resistances in a cell. A current-interrupt switch is used to open the self-calibration module circuit and either measure the IR drop using a high-frequency (MHz) ADC module, or estimate it through linear regression of acquired samples of the voltage across the sensor's working and reference electrodes (Vmeasured) over time. The IR drop is then subtracted from the closed-circuit value of Vmeasured to calculate the overpotential that exists in the cell (Vimportant). Vimportant may be further optimized by subtracting the value of the open-circuit voltage (Voc) across the sensor's working and reference electrodes. The values of Vmeasured and Vimportant are then controlled by respective first and second control units to compensate for the IR drop.
摘要翻译：用于校准特征监测系统的传感器的系统和方法实时地利用自校准模块来周期性地确定和补偿细胞中不需要的电阻的IR降。使用电流中断开关来打开自校准模块电路，并使用高频（MHz）ADC模块测量IR降压，或通过传感器工作和参考电压的采集样本的线性回归进行估计电极（Vmeasured）随着时间的推移。然后从Vmeasured的闭路电流值中减去IR降，以计算存在于电池（Vimportant）中的超电势。可以通过减去传感器的工作参考电极和参考电极之间的开路电压（Voc）的值来进一步优化V重量。然后由相应的第一和第二控制单元控制V测量和V重量的值以补偿IR下降。

7. 发明申请

US20110125446A1 METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS 有权
标题翻译：传感器稳定方法和系统
公开(公告)号：US20110125446A1
公开(公告)日：2011-05-26
申请号：US13004646
申请日：2011-01-11
申请人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
IPC分类号： G06F19/00 , G01R35/00
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14865 , A61B5/4839 , A61B2560/0223 , A61M5/1723 , A61M2230/201 , G01N27/327 , G01N27/3274
摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic—cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.
摘要翻译：血糖感测系统包括传感器和传感器电子设备。传感器包括多个电极。传感器电子设备包括稳定电路。稳定电路使得第一电压被施加到第一时间帧中的一个电极，并且使得第二电压被施加到第二时间范围中的一个电极。稳定电路重复施加第一电压和第二电压以继续阳极 - 阴极循环。传感器电子设备可以包括电源，调节器和电压施加装置，其中电压施加装置从调节器接收调节电压，在第一时间帧向电极施加第一电压，并施加第二电压第二时间段的电极。

8. 发明申请

US20110010104A1 METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS 审中-公开
公开(公告)号：US20110010104A1
公开(公告)日：2011-01-13
申请号：US12887457
申请日：2010-09-21
申请人： RAJIV SHAH , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
IPC分类号： G06F19/00 , G01N33/48
CPC分类号： G01N27/403 , A61B5/14532 , A61B5/1473 , A61B2560/0223 , A61B2562/02 , C12Q1/006 , G01N27/327 , G01N27/416
摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

9. 发明授权

US07525298B2 Implantable sensor electrodes and electronic circuitry 有权
标题翻译：可植入传感器电极和电子电路
公开(公告)号：US07525298B2
公开(公告)日：2009-04-28
申请号：US10973525
申请日：2004-10-25
申请人： Wayne A. Morgan , David Yueh-Hua Choy , John Gord , Rajiv Shah
发明人： Wayne A. Morgan , David Yueh-Hua Choy , John Gord , Rajiv Shah
IPC分类号： G01N27/00 , G01N27/26 , G01R27/26 , A61B5/05
CPC分类号： A61N1/05 , A61B5/042 , G01R27/14
摘要： An electronic circuit for sensing an output of a sensor having at least one electrode pair and circuitry for obtaining and processing the sensor output. The electrode pair may be laid out such that one electrode is wrapped around the other electrode in a U-shaped fashion. The electronic circuitry may include, among other things, a line interface for interfacing with input/output lines, a rectifier in parallel with the line interface, a counter connected to the line interface and a data converter connected to the counter and the electrode pair. The data converter may be a current-to-frequency converter. In addition, the rectifier may derive power for the electronic circuit from communication pulses received on the input/output lines.
摘要翻译：一种用于感测具有至少一个电极对的传感器的输出和用于获得和处理传感器输出的电路的电子电路。可以布置电极对，使得一个电极以U形方式缠绕在另一个电极周围。电子电路可以包括用于与输入/输出线接口的线路接口，与线路接口并联的整流器，连接到线路接口的计数器和连接到计数器和电极对的数据转换器。数据转换器可以是电流 - 频率转换器。此外，整流器可以从输入/输出线上接收的通信脉冲导出电子电路的功率。

10. 发明授权

US07369635B2 Rapid discrimination preambles and methods for using the same 有权
标题翻译：快速识别前导码和使用方法
公开(公告)号：US07369635B2
公开(公告)日：2008-05-06
申请号：US11027112
申请日：2004-12-29
申请人： Glenn O. Spital , Wayne A. Morgan , Varaz Shahmirian
发明人： Glenn O. Spital , Wayne A. Morgan , Varaz Shahmirian
IPC分类号： H04L7/00
CPC分类号： H04L7/046 , A61M5/14244 , A61M5/14276 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61N1/37211 , A61N1/37252 , A61N1/37264 , A61N1/37276 , G06F8/60 , G16H40/63 , H04L1/0061 , H04L1/1607 , Y02A90/26 , Y02D10/42
摘要： A system, method and program are disclosed for achieving rapid bit synchronization in low power medical device systems. Messages are transmitted via telemetry between a medical device and a communication device. The synchronization scheme uses a portion of a unique preamble bit pattern to identify the communication device allowing for economical communications with a minimum expenditure of energy. A special set of preamble bit patterns are utilized for their unique synchronization properties making them particularly suited for rapid bit synchronization. These unique preamble bit patterns further provide simplification to the preamble error detection logic.
摘要翻译：公开了用于实现低功率医疗设备系统中的快速位同步的系统，方法和程序。通过医疗设备和通信设备之间的遥测来发送消息。同步方案使用唯一前导码比特模式的一部分来识别通信设备，允许以最小的能量消耗进行经济通信。一组特殊的前同步码位模式被用于其独特的同步特性，使得它们特别适用于快速位同步。这些唯一的前导码比特模式进一步提供了前导码错误检测逻辑的简化。

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