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1. 发明授权

US07785652B2 Coating dispensing system and method using a solenoid head for coating medical devices 有权
标题翻译：涂布分配系统和使用螺线管头的方法用于涂覆医疗装置
公开(公告)号：US07785652B2
公开(公告)日：2010-08-31
申请号：US12467580
申请日：2009-05-18
申请人： Sheng-ping (Samuel) Zhong , Dennis R. Boulais , Praveen Kulkarni
发明人： Sheng-ping (Samuel) Zhong , Dennis R. Boulais , Praveen Kulkarni
IPC分类号： B05D3/14 , B05D1/36 , B05D1/02 , B05C11/02
CPC分类号： A61L31/18 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/602 , A61L2300/606 , A61L2420/02 , B05B5/082 , B05B12/122 , B05B12/124 , B05B12/16 , B05B13/0228 , B05B13/0442
摘要： System and method for coating a medical appliance is provided. In accord with one embodiment, a system for applying a coating to a medical appliance having accessible patterned surfaces is provided. The system may include: a processor, an appliance support, and a solenoid type fluid dispensing head having an electromagnetically controlled valve. In the system, the appliance support may be adapted to hold the medical appliance and to provide direct access for a coating to contact the exposed external patterned surfaces of the medical appliance. The solenoid type fluid dispensing head in this system may move with respect to the medical appliance and may be in communication with a source of coating and with the processor. The processor in this system may contain commands that instruct the solenoid type fluid dispensing head to force coating onto the accessible patterned surfaces of the medical appliance in a pattern that correlates with the accessible patterned surfaces of the medical appliance.
摘要翻译：提供了用于涂覆医疗器具的系统和方法。根据一个实施例，提供了一种用于将涂层施加到具有可访问的图案化表面的医疗器具的系统。该系统可以包括：处理器，器具支架和具有电磁控制阀的螺线管型流体分配头。在系统中，器具支撑件可以适于保持医疗器具，并且提供用于涂层的直接接触以接触医疗器具的暴露的外部图案化表面。该系统中的螺线管式流体分配头可以相对于医疗器具移动，并且可以与涂层和处理器连通。该系统中的处理器可以包含命令，该命令指示螺线管型流体分配头以与医疗器具的可访问的图案化表面相关联的图案强制涂覆到医疗器具的可接近图案化表面上。

2. 发明申请

US20090226601A1 COATING DISPENSING SYSTEM AND METHOD USING A SOLENOID HEAD FOR COATING MEDICAL DEVICES 有权
标题翻译：涂覆分配系统和使用用于涂敷医疗装置的电磁头的方法
公开(公告)号：US20090226601A1
公开(公告)日：2009-09-10
申请号：US12467580
申请日：2009-05-18
申请人： Sheng-ping (Samuel) Zhong , Dennis R. Boulais , Praveen Kulkarni
发明人： Sheng-ping (Samuel) Zhong , Dennis R. Boulais , Praveen Kulkarni
IPC分类号： B05D3/14
CPC分类号： A61L31/18 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/602 , A61L2300/606 , A61L2420/02 , B05B5/082 , B05B12/122 , B05B12/124 , B05B12/16 , B05B13/0228 , B05B13/0442
摘要： System and method for coating a medical appliance is provided. In accord with one embodiment, a system for applying a coating to a medical appliance having accessible patterned surfaces is provided. The system may include: a processor, an appliance support, and a solenoid type fluid dispensing head having an electromagnetically controlled valve. In the system, the appliance support may be adapted to hold the medical appliance and to provide direct access for a coating to contact the exposed external patterned surfaces of the medical appliance. The solenoid type fluid dispensing head in this system may move with respect to the medical appliance and may be in communication with a source of coating and with the processor. The processor in this system may contain commands that instruct the solenoid type fluid dispensing head to force coating onto the accessible patterned surfaces of the medical appliance in a pattern that correlates with the accessible patterned surfaces of the medical appliance.
摘要翻译：提供了用于涂覆医疗器具的系统和方法。根据一个实施例，提供了一种用于将涂层施加到具有可访问的图案化表面的医疗器具的系统。该系统可以包括：处理器，器具支架和具有电磁控制阀的螺线管型流体分配头。在系统中，器具支撑件可以适于保持医疗器具，并且提供用于涂层的直接接触以接触医疗器具的暴露的外部图案化表面。该系统中的螺线管式流体分配头可以相对于医疗器具移动，并且可以与涂层和处理器连通。该系统中的处理器可以包含命令，该命令指示螺线管型流体分配头以与医疗器具的可访问的图案化表面相关联的图案强制涂覆到医疗器具的可接近图案化表面上。

3. 发明申请

US20060070631A1 Devices and methods for agent-assisted medical procedures 有权
标题翻译：药剂辅助医疗程序的装置和方法
公开(公告)号：US20060070631A1
公开(公告)日：2006-04-06
申请号：US11231293
申请日：2005-09-21
申请人： Pual Scopton , Samuel Zhong , Yem Chin
发明人： Pual Scopton , Samuel Zhong , Yem Chin
IPC分类号： A61B19/00
CPC分类号： A61K47/10 , A61B17/22012 , A61B17/3478 , A61B2017/00269 , A61L26/008 , A61L27/52
摘要： Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.
摘要翻译：公开了膨胀或缓冲剂或材料和相关医疗装置和方法的各种实施方案。例如，在身体的管道中执行医疗程序的方法可以包括将材料注入邻近第一组织层和第二组织层之间的目标部位的液相，允许材料从液相转变为所述凝胶相响应于所述材料的温度升高至大约等于或高于所述预定温度，并且在所述靶位置上进行外科手术。在大约等于或高于预定温度的温度下，材料可以具有低于预定温度的温度和凝胶相。

4. 发明授权

US08282621B2 Devices and methods for agent-assisted medical procedures 有权
标题翻译：药剂辅助医疗程序的装置和方法
公开(公告)号：US08282621B2
公开(公告)日：2012-10-09
申请号：US13024642
申请日：2011-02-10
申请人： Paul Scopton , Samuel Zhong , Yem Chin
发明人： Paul Scopton , Samuel Zhong , Yem Chin
IPC分类号： A61M31/00
CPC分类号： A61K47/10 , A61B17/22012 , A61B17/3478 , A61B2017/00269 , A61L26/008 , A61L27/52
摘要： Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.
摘要翻译：公开了膨胀或缓冲剂或材料和相关医疗装置和方法的各种实施方案。例如，在身体的管道中执行医疗程序的方法可以包括将材料注入邻近第一组织层和第二组织层之间的目标部位的液相，允许材料从液相转变为所述凝胶相响应于所述材料的温度升高至大约等于或高于所述预定温度，并且在所述靶位置上进行外科手术。在大约等于或高于预定温度的温度下，材料可以具有低于预定温度的温度和凝胶相。

5. 发明申请

US20110196335A1 DEVICES AND METHODS FOR AGENT-ASSISTED MEDICAL PROCEDURES 有权
标题翻译：用于代理辅助医疗程序的设备和方法
公开(公告)号：US20110196335A1
公开(公告)日：2011-08-11
申请号：US13024642
申请日：2011-02-10
申请人： Paul SCOPTON , Samuel Zhong , Yem Chin
发明人： Paul SCOPTON , Samuel Zhong , Yem Chin
IPC分类号： A61M31/00
CPC分类号： A61K47/10 , A61B17/22012 , A61B17/3478 , A61B2017/00269 , A61L26/008 , A61L27/52
摘要： Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.
摘要翻译：公开了膨胀或缓冲剂或材料和相关医疗装置和方法的各种实施方案。例如，在身体的管道中执行医疗程序的方法可以包括将材料注入邻近第一组织层和第二组织层之间的目标部位的液相，允许材料从液相转变为所述凝胶相响应于所述材料的温度升高至大约等于或高于所述预定温度，并且在所述靶位置上进行外科手术。在大约等于或高于预定温度的温度下，材料可以具有低于预定温度的温度和凝胶相。

6. 发明申请

US20070225564A1 Medical devices with local drug delivery capabilities 有权
标题翻译：具有局部药物输送能力的医疗器械
公开(公告)号：US20070225564A1
公开(公告)日：2007-09-27
申请号：US11390401
申请日：2006-03-27
申请人： Lucien Couvillon , Michael Banik , (Samuel) Zhong
发明人： Lucien Couvillon , Michael Banik , (Samuel) Zhong
IPC分类号： A61B1/00
CPC分类号： A61B1/012 , A61B1/2736 , A61B1/31 , A61B5/4839 , A61M2025/0057 , A61N1/306
摘要： A medical device, for example, an endoscope or catheter, includes local drug delivery capabilities for selectively delivering at least one drug in vivo. The local drug delivery may occur as the medical device is advanced through tortuous passageways of the patient's body or may occur after the medical device has reached its targeted destination. The medical device includes a drug agent, for example, carried in or on a hydrophilic or hydrogel coating disposed on the outside thereof. When the hydrogel or drug agent receives an appropriate signal, e.g., solution containing a triggering agent or triggering condition, e.g., heat or light, the hydrogel contracts or expands to squeeze out the drug from hydrogel. If electric current is provided as the signal, and the drug agent is charged, the drug agent is released by electrophoretic forces.
摘要翻译：医疗装置，例如内窥镜或导管，包括用于在体内选择性递送至少一种药物的局部药物递送能力。当医疗设备通过患者身体的曲折通道前进时，可能发生局部药物递送，或者可能在医疗设备到达目的地之后发生。医疗装置包括例如携带在设置在其外侧的亲水或水凝胶涂层中的药剂。当水凝胶或药剂接收适当的信号，例如含有引发剂或触发条件（例如热或轻）的溶液时，水凝胶收缩或膨胀以从水凝胶中挤出药物。如果提供电流作为信号，并且药剂被充电，则药物通过电泳力释放。

7. 发明授权

US07909809B2 Devices and methods for agent-assisted medical procedures 有权
标题翻译：药剂辅助医疗程序的装置和方法
公开(公告)号：US07909809B2
公开(公告)日：2011-03-22
申请号：US11231293
申请日：2005-09-21
申请人： Paul Scopton , Samuel Zhong , Yem Chin
发明人： Paul Scopton , Samuel Zhong , Yem Chin
IPC分类号： A61M31/00
CPC分类号： A61K47/10 , A61B17/22012 , A61B17/3478 , A61B2017/00269 , A61L26/008 , A61L27/52
摘要： Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.
摘要翻译：公开了膨胀或缓冲剂或材料和相关医疗装置和方法的各种实施方案。例如，在身体的管道中执行医疗程序的方法可以包括将材料注入邻近第一组织层和第二组织层之间的目标部位的液相，允许材料从液相转变为所述凝胶相响应于所述材料的温度升高至大约等于或高于所述预定温度，并且在所述靶位置上进行外科手术。在大约等于或高于预定温度的温度下，材料可以具有低于预定温度的温度和凝胶相。

8. 发明申请

US20100234884A1 CLOSURE DEVICE WITH TEXTURED SURFACE 有权
标题翻译：带有纹理表面的封闭装置
公开(公告)号：US20100234884A1
公开(公告)日：2010-09-16
申请号：US12790554
申请日：2010-05-28
申请人： Daniel M. Lafontaine , Mark T. Ungs , William J. Drasler , Sheng-Ping (Samuel) Zhong
发明人： Daniel M. Lafontaine , Mark T. Ungs , William J. Drasler , Sheng-Ping (Samuel) Zhong
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00349 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00898 , A61B2017/12004
摘要： A closure device closes an opening in a body cavity. The closure device includes a closure member that has an external, tissue-engaging surface formed with tissue engaging surface irregularities. An elongate member is disconnectably connected to the closure member.
摘要翻译：闭合装置关闭体腔中的开口。闭合装置包括封闭构件，该封闭构件具有形成有组织接合表面不规则的外部组织接合表面。细长构件可断开地连接到闭合构件。

9. 发明授权

US07083697B2 Porous spun polymeric structures and method of making same 失效
公开(公告)号：US07083697B2
公开(公告)日：2006-08-01
申请号：US10331213
申请日：2002-12-30
申请人： Kinh-Luan (Lenny) D. Dao , Yem Chin , Sheng-ping (Samuel) Zhong , Kshitij Mohan , Liem Vu
发明人： Kinh-Luan (Lenny) D. Dao , Yem Chin , Sheng-ping (Samuel) Zhong , Kshitij Mohan , Liem Vu
IPC分类号： B01D61/14 , B01D39/16 , D04H3/16 , B29C47/06
CPC分类号： B01D71/06 , A61M1/3633 , B01D39/163 , B01D61/14 , D04H3/05 , Y10T156/1798 , Y10T428/24 , Y10T428/24479
摘要： A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 μm to about 250 μm, and a plurality of connections between the plurality of fibers. The matrix is configured so as to remove at least about 98% of leukocytes from at least one unit of packed red blood cells. Methods of making and using the matrix are also provided.

10. 发明授权

US08864738B2 Devices and methods for agent-assisted medical procedures 有权
标题翻译：药剂辅助医疗程序的装置和方法
公开(公告)号：US08864738B2
公开(公告)日：2014-10-21
申请号：US13609822
申请日：2012-09-11
申请人： Paul Scopton , Samuel Zhong , Yem Chin
发明人： Paul Scopton , Samuel Zhong , Yem Chin
IPC分类号： A61M31/00 , A61L26/00 , A61B17/22 , A61L27/52 , A61B17/34 , A61B17/00
CPC分类号： A61K47/10 , A61B17/22012 , A61B17/3478 , A61B2017/00269 , A61L26/008 , A61L27/52
摘要： Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.
摘要翻译：公开了膨胀或缓冲剂或材料和相关医疗装置和方法的各种实施方案。例如，在身体的管道中执行医疗程序的方法可以包括将材料注入邻近第一组织层和第二组织层之间的目标部位的液相，允许材料从液相转变为所述凝胶相响应于所述材料的温度升高至大约等于或高于所述预定温度，并且在所述靶位置上进行外科手术。在大约等于或高于预定温度的温度下，材料可以具有低于预定温度的温度和凝胶相。

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