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1. 发明申请

US20170255790A1 SYSTEMS AND METHODS FOR PROCESSING REQUESTS FOR GENETIC DATA BASED ON CLIENT PERMISSION DATA 有权
公开(公告)号：US20170255790A1
公开(公告)日：2017-09-07
申请号：US15163191
申请日：2016-05-24
申请人： Ryan Barrett , Othman Laraki , Wendy McKennon , Katsuya Noguchi , Huy Hong
发明人： Ryan Barrett , Othman Laraki , Wendy McKennon , Katsuya Noguchi , Huy Hong
IPC分类号： G06F21/62 , G06F17/30
CPC分类号： G06F21/6218 , G06F17/30867 , G06F21/6245 , G06F21/6254 , G06Q10/00 , G06Q50/22 , G16H10/00
摘要： Methods and systems disclosed herein relate generally to processing data requests from external assessment systems. More specifically, an interface is availed to external assessment systems that accepts an identification of one or more genes. Upon receiving a request identifying one or more genes, a type of access authorized for the requesting external assessment system is assessed. When it is determined that the type of data access indicates that the external assessment system is authorized to access data for the one or more genes, a data repository is queried to identify client data that corresponds to the one or more genes and that indicates or can be used to detect a presence of client-associated variants. A response data set that includes at least some of the client data is transmitted to the external assessment system.

2. 发明授权

US07877482B1 Efficient application hosting in a distributed application execution system 有权
标题翻译：分布式应用程序执行系统中的高效应用程序托管
公开(公告)号：US07877482B1
公开(公告)日：2011-01-25
申请号：US12060798
申请日：2008-04-01
申请人： Kenneth Ashcraft , Jon P. McAlister , Kevin A. Gibbs , Ryan Barrett
发明人： Kenneth Ashcraft , Jon P. McAlister , Kevin A. Gibbs , Ryan Barrett
IPC分类号： G06F15/173 , G06F9/00 , H04L9/32
CPC分类号： G06F9/5083 , G06F9/5022
摘要： In a distributed application execution system having an application master and a plurality of application servers, each application server includes one or more processors and memory storing one or more programs. The one of more programs include instructions for storing in non-volatile storage a plurality of applications distributed to the application server by the application master, for loading into volatile storage and executing a respective application in response to a received request, and for returning a result to the request. In addition, the one of more programs include instructions for conditionally retaining the respective application in volatile storage, for responding to a future request, when criteria, including at least predefined usage level criteria, are met by the respective application, and otherwise removing the respective application from volatile storage upon returning the result to the request.
摘要翻译：在具有应用主机和多个应用服务器的分布式应用执行系统中，每个应用服务器包括一个或多个处理器和存储一个或多个程序的存储器。更多程序之一包括用于在非易失性存储器中存储应用程序主机分发给应用服务器的多个应用程序的指令，用于响应于接收的请求加载到易失性存储器和执行相应的应用程序，并返回结果要求。此外，更多程序之一包括用于有条件地将易失性存储器中的应用保留在用于响应未来请求的指令，当包括至少预定义的使用级别标准的标准被相应应用程序满足时，以及否则移除相应的将结果返回到请求后，从易失性存储中应用。

3. 发明授权

US09817866B1 Lossless compression of client read data 有权
公开(公告)号：US09817866B1
公开(公告)日：2017-11-14
申请号：US15466325
申请日：2017-03-22
申请人： Ryan Barrett , Othman Laraki
发明人： Ryan Barrett , Othman Laraki
IPC分类号： G06F17/30
CPC分类号： H03M7/3095 , H03M7/00 , H03M7/6041
摘要： A read is aligned to a reference data set. It is determined whether the read includes any identifier distinction, the determination being performed using the alignment. If so, positional data corresponding to the identifier distinction(s) are defined. Compressed read data is stored in association with a read identifier of the read. The compressed read data includes alignment information (e.g., a start and/or stop position of the alignment). When the read includes an identifier distinction, the compressed read data further includes the positional data and deviation data characterizing the distinction.

4. 发明授权

US09811552B1 Detecting and bucketing sparse indicators for communication generation 有权
公开(公告)号：US09811552B1
公开(公告)日：2017-11-07
申请号：US15133089
申请日：2016-04-19
申请人： Katsuya Noguchi , Krishna Pant , Ryan Barrett , Elad Gil , Othman Laraki
发明人： Katsuya Noguchi , Krishna Pant , Ryan Barrett , Elad Gil , Othman Laraki
IPC分类号： G06F17/30 , G06F7/00
CPC分类号： G06F17/30371 , G06F17/30327 , G06F17/30598 , G06F17/30867
摘要： Techniques, systems, and products for analyzing sparse indicators and generating communications based on bucketing of sparse indicators are disclosed.

5. 发明授权

US09811391B1 Load balancing and conflict processing in workflow with task dependencies 有权
公开(公告)号：US09811391B1
公开(公告)日：2017-11-07
申请号：US15449579
申请日：2017-03-03
申请人： Ryan Barrett , Taylor Sittler , Krishna Pant , Zhenghua Li
发明人： Ryan Barrett , Taylor Sittler , Krishna Pant , Zhenghua Li
IPC分类号： G06F19/24 , G06F19/22 , G06F19/18 , G06F9/52 , G06F9/48
CPC分类号： G06F19/18 , G06F9/5083 , G06F19/22 , G06F19/24
摘要： Embodiments in the disclosure are directed to the use of distributed computing to align reads against multiple portions of a reference dataset. Aligned portions of the reference dataset that correspond with an above-threshold alignment score can be assessed for the presence of sparse indicators that can be categorized and used to influence a determination of a state transition likelihood. Various tasks associated with the processing of reads (e.g., alignment, sparse indicator detection, and/or determination of a state transition likelihood) may be able to take advantage of parallel processing and can be distributed among the machines while considering the resource utilization of those machines. Different load-balancing mechanisms can be employed in order to achieve even resource utilization across the machines, and in some cases may involve assessing various processing characteristics that reflect a predicted resource expenditure and/or time profile for each task to be processed by a machine.

6. 发明授权

US09813467B1 Real-time alignment and processing of incomplete stream of data 有权
公开(公告)号：US09813467B1
公开(公告)日：2017-11-07
申请号：US15452241
申请日：2017-03-07
申请人： Ryan Barrett , Taylor Sittler , Krishna Pant , Zhenghua Li , Katsuya Noguchi , Nishant Bhat
发明人： Ryan Barrett , Taylor Sittler , Krishna Pant , Zhenghua Li , Katsuya Noguchi , Nishant Bhat
IPC分类号： H04L29/08 , G06F15/16 , H04L29/06
CPC分类号： G06F17/30 , G06F17/30516
摘要： Techniques are disclosed for processing and aligning incomplete data. A stream of data is received from a data source including a plurality of reads. While receiving the stream of data and prior to having received all of the plurality of reads, a set of reads is extracted from the plurality of reads. Each of the set of reads is aligned to a corresponding portion of a reference data set. For each particular position of a plurality of particular positions of the reference data set, a subset of reads of the aligned set of reads is identified. A value of a client data set is generated based on the subset of reads. A variable is generated based on the client data set. Data is routed when a condition, based on the variable, is satisfied.

7. 发明授权

US09811439B1 Functional testing of code modifications for read processing systems 有权
公开(公告)号：US09811439B1
公开(公告)日：2017-11-07
申请号：US15489492
申请日：2017-04-17
申请人： Ryan Barrett , Krishna Pant
发明人： Ryan Barrett , Krishna Pant
IPC分类号： G06F9/44 , G06F11/36 , G06F11/26
CPC分类号： G06F11/3612 , G06F11/26
摘要： Techniques for using functional testing to detect run-time impacts of code modifications. A method includes accessing a workflow including a plurality of stages for processing reads. The stages are defined based on modifiable code and include a first stage for aligning reads with a corresponding portion of a reference data set and a second stage for collectively analyzing data corresponding to the aligned reads. The method includes identifying functional testing specifications to correspond with the workflow, including a definition of which stages are to be performed during functional testing, a reduced reference data set, and a set of reads. The method includes performing the functional testing using the reduced reference data set and the set of reads, detecting a result generated via the performance, and outputting the result.

8. 发明授权

US09785792B2 Systems and methods for processing requests for genetic data based on client permission data 有权
公开(公告)号：US09785792B2
公开(公告)日：2017-10-10
申请号：US15163191
申请日：2016-05-24
申请人： Ryan Barrett , Othman Laraki , Wendy McKennon , Katsuya Noguchi , Huy Hong
发明人： Ryan Barrett , Othman Laraki , Wendy McKennon , Katsuya Noguchi , Huy Hong
IPC分类号： G06F21/62 , G06F17/30
CPC分类号： G06F21/6218 , G06F17/30867 , G06F21/6245 , G06F21/6254 , G06Q10/00 , G06Q50/22 , G16H10/00
摘要： Methods and systems disclosed herein relate generally to processing data requests from external assessment systems. More specifically, an interface is availed to external assessment systems that accepts an identification of one or more genes. Upon receiving a request identifying one or more genes, a type of access authorized for the requesting external assessment system is assessed. When it is determined that the type of data access indicates that the external assessment system is authorized to access data for the one or more genes, a data repository is queried to identify client data that corresponds to the one or more genes and that indicates or can be used to detect a presence of client-associated variants. A response data set that includes at least some of the client data is transmitted to the external assessment system.

9. 发明授权

US09678794B1 Techniques for processing queries relating to task-completion times or cross-data-structure interactions 有权
公开(公告)号：US09678794B1
公开(公告)日：2017-06-13
申请号：US15366409
申请日：2016-12-01
申请人： Ryan Barrett , Katsuya Noguchi , Nishant Bhat , Zhengua Li , Kurt Smith
发明人： Ryan Barrett , Katsuya Noguchi , Nishant Bhat , Zhengua Li , Kurt Smith
IPC分类号： G06F9/46 , G06F9/48 , G06F11/07 , G06N99/00
CPC分类号： G06F11/3419 , G06F9/4881 , G06F9/4887 , G06F11/3024 , G06F19/00 , G06N99/005
摘要： Methods and systems disclosed herein relate generally to data processing by applying machine learning techniques to iteration data to identify anomaly subsets of iteration data. More specifically, iteration data for individual iterations of a workflow involving a set of tasks may contain a client data set, client-associated sparse indicators and their classifications, and a set of processing times for the set of tasks performed in that iteration of the workflow. These individual iterations of the workflow may also be associated with particular data sources. Using the iteration data, anomaly subsets within the iteration data can be identified, such as data items resulting from systematic error associated with particular data sources, sets of sparse indicators to be validated or double-checked, or tasks that are associated with long processing times. The anomaly subsets can be provided in a generated communication or report in order to optimize future iterations of the workflow.

10. 发明授权

US11375834B2 Coupling for a drinking straw 有权
公开(公告)号：US11375834B2
公开(公告)日：2022-07-05
申请号：US16594420
申请日：2019-10-07
申请人： Ryan Barrett
发明人： Ryan Barrett
IPC分类号： A47G21/18
摘要： A coupling including a first elongate member and a second elongate member. The first elongate member includes a first tube and a first magnet. The first tube has a first end and a second end. The first magnet secures to the first end of the first tube. The second elongate member includes a second tube and a second magnet. The second tube has a first end and a second end. The second magnet secures to the first end of the second tube. The first and second magnets are cooperatively configured to attract one another and secure the first end of the first tube to the first end of the second tube.

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