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    • 2. 发明授权
    • High-functionality polyisocyanates
    • 高官能度聚异氰酸酯
    • US07339020B2
    • 2008-03-04
    • US09811987
    • 2001-03-19
    • Bernd BruchmannHans RenzRainer KönigerUlrike EheUlrich TreulingRudolf Müller-Mall
    • Bernd BruchmannHans RenzRainer KönigerUlrike EheUlrich TreulingRudolf Müller-Mall
    • C08G18/10C08G18/72C08J9/04C07C269/02C07C271/06
    • C08G18/8022C09D175/04
    • High-functionality polyisocyanates are prepared by a process which comprises (i) preparation of an addition product (A) which contains one group which is reactive toward isocyanate and at least two isocyanate groups by reacting (a) a diisocyanate or polyisocyanate I with (b1) compounds having at least three groups which are reactive toward isocyanate or (b2) compounds containing two groups which are reactive toward isocyanate or mixtures of (b1) and (b2), where at least one of the components (a) or (b) has functional groups having differing reactivities toward the functional groups of the other component and the reaction ratio is selected so that the addition product (A) contains an average of one group which is reactive toward isocyanate, (ii) if desired, intermolecular addition reaction of the addition product (A) to form a polyaddition product (P) containing an average of one group which is reactive toward isocyanate and an average of more than two isocyanate groups, and (iii) reaction of the addition product (A) and/or the polyaddition product (P) with a diisocyanate or polyisocyanate II.
    • 通过以下方法制备高官能度多异氰酸酯:(i)通过使(a)二异氰酸酯或多异氰酸酯I与(b1)反应,制备含有一个对异氰酸酯和至少两个异氰酸酯基反应的基团的加成产物(A) )具有至少三个对异氰酸酯反应的基团的化合物或(b2)含有对异氰酸酯或(b1)和(b2)的混合物具有反应性的两个基团的化合物,其中至少一种组分(a)或(b) 具有与其他成分的官能团反应性不同的官能团,选择反应比,使加成产物(A)含有对异氰酸酯具有反应性的一个基团的平均值,(ii)如果需要,分子内加成反应 加成产物(A)形成含有平均一个对异氰酸酯反应的基团和平均多于两个异氰酸酯基团的加聚产物(P),和(iii)反应 加成产物(A)和/或加聚产物(P)与二异氰酸酯或多异氰酸酯II的离子。
    • 4. 发明授权
    • Methods of synthesis for 9-substituted hypoxanthine derivatives
    • 9-取代次黄嘌呤衍生物的合成方法
    • US06849735B1
    • 2005-02-01
    • US09602048
    • 2000-06-23
    • Alvin J. GlaskyHeinrich BollingerHans Rudolf Müller
    • Alvin J. GlaskyHeinrich BollingerHans Rudolf Müller
    • A61P25/28C07D233/88C07D233/90C07D473/30
    • C07D233/90C07D473/30
    • An improved method of synthesis of a 9-substituted hypoxanthine derivative comprises the steps of: (1) reacting aminocyanacetamide with triethyl orthoformate to form an imidoester derivative of aminocyanacetamide; (2) forming a compound having a reactive amino group on a hydrocarbyl moiety, the hydrocarbyl moiety being linked through an amide group to a physiologically active moiety or an esterified derivative of a physiologically active moiety including therein an esterified benzoyl group; (3) reacting the imidoester with the compound having the reactive amino group on the hydrocarbyl moiety to form a derivative of aminoimidazole-4-carboxamide substituted at the 1-position with a hydrocarbyl moiety linked through an amide group to a physiologically active moiety including therein an optionally esterified benzoyl group; (4) forming the six-membered heterocyclic ring of the purine moiety of the hypoxanthine by reacting the derivative of 5-aminoimidazole-4-carboxamide formed in step (3) with triethyl orthoformate to form a 9-substituted hypoxanthine compound substituted at the 9-position with a hydrocarbyl moiety linked through an amide group to a physiologically active moiety including therein an optionally esterified benzoyl group; and (5) hydrolyzing the ester of the optionally esterified benzoyl group if present.
    • 合成9-取代的次黄嘌呤衍生物的改进方法包括以下步骤:(1)使氨基异氰酸乙酰胺与原甲酸三乙酯反应,形成氨基异氰酸乙酰胺的酰亚胺酯衍生物; (2)在烃基部分上形成具有反应性氨基的化合物,烃基部分通过酰胺基与生理活性部分或生理活性部分的酯化衍生物连接,其中包括酯化苯甲酰基; (3)使酰亚胺酯与在烃基部分上具有反应性氨基的化合物反应,以形成在1-位取代的氨基咪唑-4-甲酰胺的衍生物,其中烃基部分通过酰胺基团连接到包括其中的生理活性部分 任选酯化的苯甲酰基; (4)通过使步骤(3)中形成的5-氨基咪唑-4-甲酰胺的衍生物与原甲酸三乙酯反应形成在9位被取代的9-取代的次黄嘌呤化合物,形成次黄嘌呤嘌呤部分的六元杂环 - 具有通过酰胺基团连接到生理活性部分的烃基部分,其中包括任选酯化的苯甲酰基; 和(5)水解任意酯化的苯甲酰基的酯(如果存在)。
    • 5. 发明授权
    • Method for the attachment of a functional element to a sheet metal part and also a component assembly
    • 用于将功能元件附接到钣金件以及元件组件的方法
    • US07155798B2
    • 2007-01-02
    • US10896459
    • 2004-07-22
    • Rudolf MüllerJiri Babej
    • Rudolf MüllerJiri Babej
    • B23P11/00F16B37/00
    • B23P19/062Y10T29/4992Y10T29/49943Y10T29/49956Y10T29/49963Y10T29/49966Y10T403/4966Y10T403/4991
    • A method for the attachment of a functional element, for example in the form of an RSN or RND element of the company Profil Verbindungstechnik GmbH & Co. KG, is described in which the hole in the sheet metal part is so formed that the sheet metal part lies in one plane in the region confronting the end face of the riveting die button and at least substantially does not project beyond this plane. The hole in the sheet metal part has an inner diameter which is larger than the outer diameter of the rivet section of the element, ignoring any features present there providing security against rotation, by an amount which ensures that the marginal region of the hole is deformed by the action of the riveting die button out of the sheet metal plane and in the direction of the body section of the functional element before the marginal region of the hole enters into contact with the riveting section as a result of the formation of the rivet bead, so that neither a bending of the marginal region of the hole out of the sheet metal plane nor the formation of the rivet bead is prevented.
    • 描述了一种用于附接功能元件的方法,例如以Profil Verbindungstechnik GmbH&Co. KG公司的RSN或RND元件的形式,其中钣金零件中的孔形成为使得金属板 部分位于面对铆接模具按钮的端面的区域中的一个平面中,并且至少基本上不突出超出该平面。 金属板部分的孔的内径大于元件的铆钉部分的外径,忽略存在于其中的任何特征,提供抵抗旋转的安全性,保证孔的边缘区域变形 通过铆接模具按钮从金属板的平面和功能元件的主体部分的方向的作用,在孔的边缘区域由于形成铆钉珠而与铆接部分接触 ,使得不会使孔的边缘区域从金属板的平面弯曲,也不会形成铆钉珠。
    • 7. 发明授权
    • Clinching device with movable lever
    • 带移动杆的夹紧装置
    • US06651300B1
    • 2003-11-25
    • US09806073
    • 2001-05-11
    • Rudolf Müller
    • Rudolf Müller
    • B23P1100
    • B21D39/031Y10T29/49936Y10T29/49938Y10T29/53678Y10T29/53709
    • A clenching device for generating a clenching connection between a first workpiece and a second workpiece using a plunger which is movable from above into a recess of a die, wherein a peripheral wall of the recess has stationary wall sections which extend essentially parallel to a pressure direction. The peripheral wall of the recess has between the stationary wall sections movable wall sections which are arranged on levers. The levers are movable by pressures from above into a working position and are securable therein and from undercut areas and are movable by movement of the workpieces after the workpieces have been jointed in the upward direction into a release position in which the undercut areas are completely released.
    • 一种紧固装置,用于使用可从上方移动到模具的凹部中的柱塞在第一工件和第二工件之间产生紧固连接,其中所述凹部的周壁具有基本平行于压力方向延伸的固定壁部分 。 凹槽的周壁在设置在杆上的固定壁部分可移动壁部分之间。 杠杆可以通过压力从上方移动到工作位置,并且可以在其中固定并且从底切区域移动,并且在工件已经沿向上方向被接合到释放位置之后通过工件的移动可移动到其中底切区域被完全释放 。
    • 8. 发明授权
    • Polyisocyanates
    • 聚异氰酸酯
    • US06416686B2
    • 2002-07-09
    • US09811201
    • 2001-03-16
    • Bernd BruchmannHans RenzRainer KönigerUlrike EheUlrich TreulingRudolf Müller-Mall
    • Bernd BruchmannHans RenzRainer KönigerUlrike EheUlrich TreulingRudolf Müller-Mall
    • C08G1830
    • C08G18/8016C08G18/79C08G18/8041
    • Polyisocyanates are prepared by a process which comprises (i) preparation of an addition product (A) which contains one group which is reactive toward isocyanate and one isocyanate group by reacting (a) a diisocyanate I with (b) compounds containing two groups which are reactive toward isocyanate, where at least one of the components (a) or (b) has functional groups having differing reactivities toward the functional groups of the other component, (ii) if desired, intermolecular addition reaction of the addition product (A) to form a polyaddition product (P) which contains one group which is reactive toward isocyanate and one isocyanate group and (iii) reaction of the addition product (A) and/or the polyaddition product (P) with a diisocyanate or polyisocyanate II which is different from diisocyanate I.
    • 聚异氰酸酯是通过以下方法制备的:(i)通过使(a)二异氰酸酯I与(b)含有两个基团的化合物反应而制备含有一个对异氰酸酯和一个异氰酸酯基反应的基团的加成产物(A) 对于异氰酸酯反应,其中组分(a)或(b)中的至少一种具有与其它组分的官能团不同的反应性的官能团,(ii)如果需要,加成产物(A)的分子内加成反应与 形成加成产物(P),其包含一个对异氰酸酯和一个异氰酸酯基反应的基团,和(iii)加成产物(A)和/或加聚产物(P)与不同的二异氰酸酯或多异氰酸酯II的反应 来自二异氰酸酯I.