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1. 发明申请

US20100274170A1 RADIAL DESIGN OXYGENATOR WITH HEAT EXCHANGER 有权
标题翻译：带热交换器的径向设计氧化剂
公开(公告)号：US20100274170A1
公开(公告)日：2010-10-28
申请号：US12428674
申请日：2009-04-23
申请人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
发明人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
IPC分类号： A61M1/36
CPC分类号： A61M1/1698
摘要： Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises: a core that is substantially centrally located in the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the core and between which blood from the core can move radially outward; and an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and between which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.
摘要翻译：公开了一种用于对体外循环中的血液进行氧化和控制的装置。该装置具有从入口径向向外定位的入口和出口，以便限定穿过该装置的流路。所述装置包括：基本中心地位于所述装置中的芯，并且来自患者的血液可以通过所述入口供应到所述芯; 一种热交换器，包括多个传热元件，所述多个传热元件布置在所述芯部周围，并且来自所述芯体的血液可径向向外移动; 以及包括多个气体交换元件的氧合器，所述多个气体交换元件布置在所述热交换器周围，并且在通过所述出口离开所述设备之前，来自所述热交换器的血液可径向向外移动。

2. 发明授权

US07204958B2 Extracorporeal blood circuit air removal system and method 有权
标题翻译：体外血液回路除气系统及方法
公开(公告)号：US07204958B2
公开(公告)日：2007-04-17
申请号：US10743598
申请日：2003-12-22
申请人： Robert W. Olsen , Walter L. Carpenter , John B. Dickey , Frederick A. Shorey , Laura A. Yonce , Mark D. Stringham
发明人： Robert W. Olsen , Walter L. Carpenter , John B. Dickey , Frederick A. Shorey , Laura A. Yonce , Mark D. Stringham
IPC分类号： A61M1/14 , A61M37/00 , C02F1/44 , B01D53/22
CPC分类号： A61M1/3627 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1086 , A61M1/1089 , A61M1/32 , A61M1/3626 , A61M1/3664 , A61M1/3666 , A61M1/3667 , A61M1/367 , A61M2205/3379 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2205/8206 , A61M2209/08 , A61M2209/082 , Y10S261/28
摘要： A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to conserve volume, to reduce setup and change out times, to eliminate a blood reservoir, and to substantially reduce blood-air interface. Blood from the patient or prime solution is routed through an air removal device that is equipped with air sensors for detection of air. An active air removal controller removes detected air from blood in the air removal device. A disposable circuit support module is used to mount the components of the disposable, integrated extracorporeal blood circuit in close proximity and in a desirable spatial relationship to optimize priming and use of the disposable, integrated extracorporeal blood circuit. A reusable circuit holder supports the disposable circuit support module in relation to a prime solution source, the active air removal controller and other components.
摘要翻译：在体外循环手术中使用的一次性，综合的体外血液回路以节省体积，减少建立和改变时间，消除血液储存器和大大减少血液的方式进行气体交换，热传递和微栓塞过滤功能 - 界面。来自患者或主溶液的血液通过装备有用于检测空气的空气传感器的空气去除装置。主动除气控制器从空气去除装置中的血液中除去检测到的空气。一次性电路支持模块用于将一次性的，集成的体外血液回路的部件安装在非常接近的位置并且具有期望的空间关系，以优化一次性的，集成的体外血液回路的灌注和使用。一个可重复使用的电路支架支持一次性电路支撑模块相对于主要解决方案源，主动空气去除控制器和其他组件。

3. 发明授权

US07201870B2 Active air removal system operating modes of an extracorporeal blood circuit 有权
公开(公告)号：US07201870B2
公开(公告)日：2007-04-10
申请号：US10743116
申请日：2003-12-22
申请人： Robert W. Olsen , Walter L. Carpenter , John B. Dickey , Mark D. Stringham
发明人： Robert W. Olsen , Walter L. Carpenter , John B. Dickey , Mark D. Stringham
IPC分类号： A61M1/14 , A61M37/00 , C02F1/44 , B01D53/22
CPC分类号： A61M1/3643 , A61M1/3626 , A61M1/3627 , A61M1/3644 , A61M1/3666 , A61M1/3667 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2209/082 , Y10S261/28
摘要： A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to conserve volume, to reduce setup and change out times, to eliminate a venous blood reservoir, and to substantially reduce blood-air interface. Blood from the patient or prime solution is routed through an air removal device that is equipped with air sensors for detection of air. An active air removal controller removes detected air from blood in the air removal device. A disposable circuit support module is used to mount the components of the disposable, integrated extracorporeal blood circuit in close proximity and in a desirable spatial relationship to optimize priming and use of the disposable, integrated extracorporeal blood circuit. A reusable circuit holder supports the disposable circuit support module in relation to a prime solution source, the active air removal controller and other components.

4. 发明授权

US07198751B2 Disposable, integrated, extracorporeal blood circuit 有权
标题翻译：一次性，一体化，体外血液循环
公开(公告)号：US07198751B2
公开(公告)日：2007-04-03
申请号：US10743373
申请日：2003-12-22
申请人： Walter L. Carpenter , Robert W. Olsen , Stefanie Heine , Frederick A. Shorey, Jr. , Laura A. Yonce
发明人： Walter L. Carpenter , Robert W. Olsen , Stefanie Heine , Frederick A. Shorey, Jr. , Laura A. Yonce
IPC分类号： A61M1/14 , A61M37/00 , C02F1/44 , B01D53/22
CPC分类号： A61M1/1698 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1086 , A61M1/1089 , A61M1/1629 , A61M1/32 , A61M1/3626 , A61M1/3627 , A61M1/3639 , A61M1/3643 , A61M1/3644 , A61M1/3666 , A61M1/3667 , A61M2205/3379 , A61M2205/3382 , A61M2205/3386 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2205/8206 , A61M2209/08 , A61M2209/082 , Y10S261/28
摘要： A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to conserve volume, to reduce setup and change out times, to eliminate a venous blood reservoir, and to substantially reduce blood-air interface. Blood from the patient or prime solution is routed through an air removal device that is equipped with air sensors for detection of air. An active air removal controller removes detected air from blood in the air removal device. A disposable circuit support module is used to mount the components of the disposable, integrated extracorporeal blood circuit in close proximity and in a desirable spatial relationship to optimize priming and use of the disposable, integrated extracorporeal blood circuit. A reusable circuit holder supports the disposable circuit support module in relation to a prime solution source, the active air removal controller and other components.
摘要翻译：在体外循环手术中使用的一次性，一体化的体外血液回路以节省体积，减少安装和更换时间，消除静脉血液储存器的方式进行气体交换，热传递和微栓塞过滤功能，并且显着减少血液空气界面。来自患者或主溶液的血液通过装备有用于检测空气的空气传感器的空气去除装置。主动除气控制器从空气去除装置中的血液中除去检测到的空气。一次性电路支持模块用于将一次性的，集成的体外血液回路的部件安装在非常接近的位置并且具有期望的空间关系，以优化一次性的，集成的体外血液回路的灌注和使用。一个可重复使用的电路支架支持一次性电路支撑模块相对于主要解决方案源，主动空气去除控制器和其他组件。

5. 发明授权

US5782791A Method of manufacturing a fluid filter 失效
标题翻译：制造流体过滤器的方法
公开(公告)号：US5782791A
公开(公告)日：1998-07-21
申请号：US626254
申请日：1996-03-29
申请人： Richard O. Peterson , Robert W. Olsen
发明人： Richard O. Peterson , Robert W. Olsen
IPC分类号： A61M1/34 , A61M1/36 , B01D29/01 , B01D29/07 , B01D29/11 , B01D35/02 , B01D36/00 , B01D63/14 , A61M37/00 , B01D19/00
CPC分类号： B01D36/001 , A61M1/3627 , B01D29/012 , B01D29/111 , Y10T156/1025
摘要： A method of manufacturing a fluid filter comprising: (a) providing a cone having a tip end and an open end and made of a filter material; (b) providing a support element having a plurality of concentric annular members mounted on a base and having outermost and innermost concentric annular members; (c) aligning the central axes of the cone and the support element with the tip end of the cone closest to the support element; and (d) inserting a portion of the cone into a circular area between two concentric annular members by placing a forming sleeve inside the cone and inserting the forming sleeve between the two concentric annular members, the concentric annular members being generally cylindrical and having an interior and an exterior.
摘要翻译：一种制造流体过滤器的方法，包括：（a）提供具有尖端和开口端并由过滤材料制成的锥体; （b）提供一种支撑元件，该支撑元件具有安装在基座上并具有最外和最内同心环形构件的多个同心环形构件; （c）使所述锥体和所述支撑元件的中心轴线与最靠近所述支撑元件的所述锥体的顶端对齐; 和（d）通过将成形套筒放置在锥体内并将成形套筒插入两个同心环形构件之间，将锥体的一部分插入到两个同心环形构件之间的圆形区域中，同心环形构件通常为圆柱形并具有内部和外观。

6. 发明授权

US5048253A Louver with maximum free area 失效
标题翻译：最大免费区域的百叶窗
公开(公告)号：US5048253A
公开(公告)日：1991-09-17
申请号：US636753
申请日：1991-01-02
申请人： Robert W. Olsen
发明人： Robert W. Olsen
IPC分类号： E06B7/082 , E06B7/084 , F24F13/08 , F24F13/15
CPC分类号： F24F13/08 , E06B7/082 , E06B7/084 , F24F13/15 , F24F13/082
摘要： The cross sections of louver blades are located exclusively within zones defined primarily by concentric arcs configured to maintain a substantially equal spacing between the boundaries of the zones of adjacent blades throughout the width of the louver.
摘要翻译：百叶窗叶片的横截面仅位于主要由同心弧限定的区域内，该同心圆弧被构造成在百叶窗宽度上在相邻叶片区域的边界之间保持基本相等的间隔。

7. 发明授权

US4103468A Drainable blade louver 失效
标题翻译：可排水叶片百叶窗
公开(公告)号：US4103468A
公开(公告)日：1978-08-01
申请号：US790025
申请日：1977-04-22
申请人： Robert W. Olsen
发明人： Robert W. Olsen
IPC分类号： E06B7/082 , E06B7/00 , F24F13/08
CPC分类号： F24F13/08
摘要： A drainable blade louver comprises a pair of spaced-apart vertical members supporting a multiplicity of elongated, horizontally extending, inclined blades, each of which is of uniform cross section along its length. Each blade has an upwardly open front drainage trough located adjacent the front edge of the blade and at least one second upwardly open drainage trough located in at least about the front one-third of the blade closely adjacent the front trough. Each of the troughs is defined by spaced-apart front and back walls, the upper edges of which are preferably located in a plane substantially parallel to the airflow streams passing between the blades, and a bottom wall spaced a substantial distance below the upper edges of the front and back walls such that the splash from water drops impinging on the bottom walls of the troughs is largely confined to the zone bounded by the walls of the troughs thereby minimizing entrainment of water in the airflow streams.
摘要翻译：可排出的叶片百叶窗包括一对间隔开的垂直构件，其支撑多个细长的，水平延伸的倾斜叶片，每个叶片沿其长度具有均匀的横截面。每个叶片具有位于叶片前边缘附近的向上敞开的前排水槽，以及至少一个第二向上开放的排水槽，其至少围绕与前槽紧邻的叶片的前1/3。每个槽由间隔开的前壁和后壁限定，其上边缘优选地位于基本上平行于通过叶片之间的气流的平面中，以及在壁的上边缘之间隔开相当距离的底壁前壁和后壁使得水滴溅落在槽的底壁上大部分被限制在由槽的壁限定的区域中，从而最小化气流中的水的夹带。

8. 发明授权

US08545754B2 Radial design oxygenator with heat exchanger 有权
标题翻译：径向设计加氧器与换热器
公开(公告)号：US08545754B2
公开(公告)日：2013-10-01
申请号：US12428674
申请日：2009-04-23
申请人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
发明人： Walt L. Carpenter , Robert W. Olsen , Michael J. Hobday , Alford L. McLevish , Christopher J. Plott , Roderick E. Briscoe , Patrick J. Cloutier , Anil Thapa , Ming Li , Kevin McIntosh , Ken Merte
IPC分类号： A61M1/00 , A61M1/16
CPC分类号： A61M1/1698
摘要： Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises: a core that is substantially centrally located in the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the core and between which blood from the core can move radially outward; and an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and between which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.
摘要翻译：公开了一种用于对体外循环中的血液进行氧化和控制的装置。该装置具有从入口径向向外定位的入口和出口，以便限定穿过该装置的流路。所述装置包括：基本中心地位于所述装置中的芯，并且来自患者的血液可以通过所述入口供应到所述芯; 一种热交换器，包括多个传热元件，所述多个传热元件布置在所述芯部周围，并且来自所述芯体的血液可径向向外移动; 以及包括多个气体交换元件的氧合器，所述多个气体交换元件布置在所述热交换器周围，并且在通过所述出口离开所述设备之前，来自所述热交换器的血液可径向向外移动。

9. 发明授权

US5951949A Heat exchanger for medical applications 失效
标题翻译：医疗用热交换器
公开(公告)号：US5951949A
公开(公告)日：1999-09-14
申请号：US993917
申请日：1997-12-18
申请人： Robert W. Olsen
发明人： Robert W. Olsen
IPC分类号： F28F3/08 , A61M1/36 , A61M5/44 , A61M1/14 , A61M1/34
CPC分类号： A61M5/44 , A61M2205/366
摘要： A heat exchanger for medical applications is disclosed. The heat exchanger is characterized in that it is configured to provide a high heat transfer efficiency while minimizing the possibility of formation gaseous emboli and maximizing the ability to entrap and remove any such emboli which form or are introduced into the device. The heat exchanger has a corrugated tubular core which is configured to minimize the chances of entrapping air during the potting process.
摘要翻译：公开了用于医疗应用的热交换器。热交换器的特征在于，其构造成提供高的传热效率，同时最小化形成气体栓塞的可能性并且最大限度地捕获和去除形成或被引入到装置中的任何这样的栓塞的能力。热交换器具有波纹管状芯，其被构造成使得在灌封过程期间截留空气的机会最小化。

10. 发明授权

US5462619A Mass transfer device having a hollow fiber bundle 失效
标题翻译：具有中空纤维束的质量传递装置
公开(公告)号：US5462619A
公开(公告)日：1995-10-31
申请号：US276950
申请日：1994-07-19
申请人： William S. Haworth , Robert W. Olsen , Mark S. Goodin
发明人： William S. Haworth , Robert W. Olsen , Mark S. Goodin
IPC分类号： A61M1/18 , B01D63/02 , B01D63/10 , B65H81/00 , B65H81/06
CPC分类号： B01D63/021 , B01D63/02 , B01D63/025 , B65H2701/38
摘要： A mass transfer device including a hollow fiber bundle wound on a core for radially outward flow of a first fluid. The core has an axis extending from one end to the other. The hollow fiber bundle has packing fractions which increase radially outward of the core's axis for a major portion of the bundle. Methods for making such mass transfer device.
摘要翻译：一种传质装置，包括缠绕在芯上的中空纤维束，用于第一流体的径向向外流动。芯具有从一端延伸到另一端的轴线。中空纤维束具有填充部分，其对于芯的主要部分的径向向外径向增加。制造这种传质装置的方法。

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