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    • 2. 发明授权
    • Method of and device for improving a drainage of aqueous humor within the eye
    • 改善眼内房水排泄的方法和装置
    • US06375642B1
    • 2002-04-23
    • US09503884
    • 2000-02-15
    • Hans R. GrieshaberM. D. Robert Stegmann
    • Hans R. GrieshaberM. D. Robert Stegmann
    • A61M3500
    • A61F9/00781A61F2210/0004
    • A method for improving a drainage of aqueous humor in an eye of a living being and a device for maintaining the drainage of aqueous humor are described, wherein a first incision is made in a lamellar section of the sclera to form a first scleral flap which is then folded upwards in the direction of the cornea, thereby creating a recess in the sclera. A second scleral flap is formed by incising a second lamellar section in the area of the recess and lifted upwardly in the direction of the first sclera flap, thereby creating a second recess and exposing a portion of the Schlemm's canal for permitting injection of a highly viscous medium. At least one support element is implanted in the lumen of the Schlemm's canal on each of both sides of the second recess and, optionally, in the exposed portion of the Schlemm's canal, whereby each of the support elements is made of a material that is decomposable by the tissue of the Schlemm's canal and/or aqueous humor. For formation of a gap-like opening, the second scleral flap or a portion thereof is detached from the partially aqueous humor-permeable Descemet's membrane in the area of the Schwalbe's line, and the detached portion is held open by several protrusions formed on the support element implanted in the exposed portion of the Schlemm's canal.
    • 描述了一种用于改善活体眼睛中的房水的引流的方法和用于维持房水引流的装置的方法,其中在巩膜的层状部分中形成第一切口以形成第一巩膜瓣,其为 然后沿着角膜的方向向上折叠,从而在巩膜中形成凹陷。 通过在凹陷区域中切割第二层状区段并沿着第一巩膜瓣的方向向上提升形成第二巩膜瓣,从而产生第二凹陷并暴露出一部分施勒姆氏管以允许注射高粘度 中。 至少一个支撑元件植入Schlemm运河的内腔,位于第二凹槽的两侧,并且任选地植入施莱姆管的暴露部分,由此每个支撑元件由可分解的材料制成 通过施莱姆氏运河和/或房水的组织。 为了形成间隙状开口,第二巩膜瓣或其一部分在Schwalbe线的区域中与部分透水的Descemet膜分离,并且分离部分由形成在支撑体上的若干突起保持打开 元素植入Schlemm运河的暴露部分。
    • 4. 发明授权
    • Ophthalmic implant for treatment of glaucoma
    • 用于治疗青光眼的眼科植入物
    • US08034105B2
    • 2011-10-11
    • US11305306
    • 2005-12-16
    • Robert StegmannStanley R. ConstonDavid J. KupieckiJohn McKenzieCandice D. PinsonRonald K. Yamamoto
    • Robert StegmannStanley R. ConstonDavid J. KupieckiJohn McKenzieCandice D. PinsonRonald K. Yamamoto
    • A61F2/14A61M5/00
    • A61F9/00781
    • A method is provided for increasing the outflow of fluid through Schlemm's canal that is useful for treatment of glaucoma. The implant is placed in Schlemm's canal by use of a flexible delivery instrument attached to the implant. The instrument and implant are positioned within the canal, the implant is released and the distal and proximal ends of the implant are connected to apply sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability. In another embodiment a delivery instrument attached to the implant is positioned in the canal securing one of the distal or proximal ends of the implant within the canal. The implant provides sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability of the inner wall of the canal. The other of the distal or proximal ends may be secured to maintain the tensioning force on the inner wall of the canal.
    • 提供了一种增加流体穿过施莱姆氏管的流出方法,可用于治疗青光眼。 通过使用附着在植入物上的柔性递送器械将植入物置于施莱姆氏管中。 仪器和植入物定位在管内,植入物被释放,并且植入物的远端和近端被连接以在管的内壁上施加足够的轴向张力以增加流体渗透性。 在另一个实施例中,附接到植入物的递送器械定位在将移植物的远端或近端中的一端固定在管内的运河中。 植入物在管道的内壁上提供足够的轴向张力,以增加管道内壁的流体渗透性。 远端或近端中的另一个可以被固定以保持在管的内壁上的张紧力。
    • 7. 发明申请
    • METHOD AND DEVICE FOR THE TREATMENT OF GLAUCOMA
    • 用于治疗葡萄球菌的方法和装置
    • US20110118649A1
    • 2011-05-19
    • US12618326
    • 2009-11-13
    • Robert StegmannMatthias GrieshaberHans Grieshaber
    • Robert StegmannMatthias GrieshaberHans Grieshaber
    • A61F9/00A61M27/00
    • A61F9/00781A61B2090/3937A61F9/0017
    • The invention relates to a method and a device for treatment of glaucoma, wherein by means of an elongated catheter provided with a distal portion and a proximal portion, a tube-shaped implant is inserted and released in a Schlemm's canal with two opposite openings exposed by an incision and a folded up scleral flap. In a first phase, the distal portion inserted into the Schlemm's canal through the first opening, while a fluid or gaseous medium is injected at the same time, and exited through the second opening, which is, in circumferential direction, oppositely located. The implant detachably disposed at the protruding distal portion and, in a second phase, inserted, in circumferential direction, into the expanded Schlemm's canal up to the first opening. Subsequently, the distal portion, which protrudes from the first opening, is detached from the implant and, together with the catheter, removed.
    • 本发明涉及一种用于治疗青光眼的方法和装置,其中通过设置有远侧部分和近端部分的细长导管,将管状植入物插入并释放在施莱姆管中,其中两个相对的开口暴露于 切口和折叠巩膜瓣。 在第一阶段中,远端部分通过第一开口插入施莱姆管道,同时流体或气体介质同时注入,并通过位于圆周方向上相对定位的第二开口排出。 所述植入物可拆卸地设置在所述突出远端部分处,并且在第二阶段中,沿圆周方向插入所述扩张的施莱姆氏管中直到所述第一开口。 随后,从第一开口突出的远端部分与植入物分离,并与导管一起被移除。
    • 8. 发明授权
    • Method of and device for improving the flow of aqueous humor within the eye
    • 改善眼内房水流动的方法和装置
    • US06726676B2
    • 2004-04-27
    • US09478047
    • 2000-01-05
    • Robert StegmannHans R. Grieshaber
    • Robert StegmannHans R. Grieshaber
    • A61M2500
    • A61F9/00781
    • A method for improving the draining of aqueous humor in an eye of a living being and a device for widening the Schlemm's canal is described wherein a first incision is made in a lamellar section of the sclera to form a first scleral flap which is then folded upwards in the direction of the cornea, thereby creating a recess in the sclera. A second scleral flap is formed by incising a second lamellar section in the area of the recess and lifted upwardly in the direction of the first sclera flap, thereby exposing two opposite openings into the Schlemm's canal into which an expanding medium is injected into the Schlemm's canal; formation of a slitlike passageway connecting the aqueous humor-permeable Descemet-membrane with the subscleral space is realized by detaching the Descemet-membrane on the area of the Schwalbe's line by means of a slight pressure force; and subsequently, the first scleral flap folded back, after severance of the second scleral flap, for placement upon a support surface formed as a consequence of the incision of the second lamellar section. Subsequently, a viscous medium is injected into a subscleral space formed behind the first scleral flap and the first scleral flap is rejoined to the sclera.
    • 描述了一种用于改善生活眼中的房水的排水和用于扩大施莱姆氏管的装置的方法,其中在巩膜的层状部分中制备第一切口以形成第一巩膜瓣,然后将其向上折叠 在角膜的方向,从而在巩膜中形成凹陷。 通过在凹陷区域中切割第二层状区段并沿着第一巩膜瓣的方向向上提升而形成第二巩膜瓣,从而将两个相对的开口暴露于施莱姆氏管中,将扩张介质注入到施莱姆氏管中 ; 通过利用轻微的压力力分离在Schwalbe线的区域上的Descemet膜,可以实现将房水透湿的Descemet膜与子载波空间相连接的狭缝状通道的形成; 并且随后,在第二巩膜瓣切除之后,第一巩膜瓣折回,以便放置在由于第二层片切口的切口形成的支撑表面上。 随后,将粘性介质注射到形成在第一巩膜瓣后面的下伏的空间中,并且将第一巩膜瓣重新连接至巩膜。
    • 10. 发明授权
    • Ophthalmic surgical apparatus for macerating and removing the lens
nucleus from the eye of a living being
    • 用于从生命的眼睛中浸没和去除晶状体核的眼科手术装置
    • US5693062A
    • 1997-12-02
    • US472055
    • 1995-06-06
    • Robert StegmannRudolf Demmerle
    • Robert StegmannRudolf Demmerle
    • A61F9/007A61M1/00A61B17/32
    • A61F9/00763
    • An ophthalmic surgical device for macerating the lens nucleus in the eye and for removing particles of the macerated lens nucleus from the eye of a living being, includes a hand-held housing with a head piece attached at one axial end of the housing and supporting a guide tube. Disposed in the guide tube is a tubular probe which is operatively connected to a motor drive and projects beyond the guide tube with its tip to carry a cutting element in form of at least two rotatable wing-like blades oriented approximately transversely to the longitudinal axis of the guide tube. By means of the drive, the tubular probe is rotatable relative to the stationary guide tube about the longitudinal axis and movable at a high frequency in direction of the longitudinal axis.
    • 一种用于使眼睛中的晶状体核浸没并从活体的眼睛去除浸没的晶状体核的颗粒的眼科手术装置包括手持式壳体,其具有附接在壳体的一个轴向端部处并支撑 导管。 设置在导管中的管状探针是可操作地连接到马达驱动器的管状探针,并且突出超过引导管的尖端,以将至少两个可旋转的翼状叶片形式的切割元件形成为大致横向于纵向轴线 导管。 通过驱动器,管状探针相对于固定引导管围绕纵向轴线可旋转并且可在纵轴方向上以高频率移动。