专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09809621B2 Stable peptide-based PACE4 inhibitors 有权
公开(公告)号：US09809621B2
公开(公告)日：2017-11-07
申请号：US14342041
申请日：2012-08-30
申请人： Robert Day , Witold A. Neugebauer , Yves Dory
发明人： Robert Day , Witold A. Neugebauer , Yves Dory
IPC分类号： A61K38/00 , C07K9/00 , C07K7/06 , A61K47/48 , A61K38/08 , A61K45/06
CPC分类号： C07K7/06 , A61K38/00 , A61K38/08 , A61K45/06 , A61K47/542 , A61K47/60 , Y02A50/469 , Y02A50/475
摘要： It is provided PACE4 inhibitors and their uses for treating infection, cancer. Particularly, it is provided a method or use for the treatment of a cancer in a subject, comprising administering to the subject a therapeutically effective amount of the PACE4 inhibitors or the composition disclosed.

2. 发明授权

US08658591B2 Multi-LEU peptides and analogues thereof as selective PACE4 inhibitors and effective antiproliferative agents 有权
标题翻译：多LEU肽及其类似物作为选择性PACE4抑制剂和有效的抗增殖剂
公开(公告)号：US08658591B2
公开(公告)日：2014-02-25
申请号：US13003628
申请日：2009-07-06
申请人： Robert Day , Martin Fugère , Witold A. Neugebauer
发明人： Robert Day , Martin Fugère , Witold A. Neugebauer
IPC分类号： A61K38/00 , A61P35/00
CPC分类号： C07K7/06 , A61K38/00 , C07K5/1019 , C07K14/811 , C12Q1/37 , G01N2333/96438 , G01N2500/04
摘要： Disclosed herein are PACE4 inhibitors, compositions comprising PACE4 inhibitors and their uses thereof for lowering PACE4 activity, reducing cell proliferation, reducing tumor growth, reducing metastasis formation, preventing and/or treating cancer. Also provided are methods for lowering PACE4 activity, reducing the proliferation of a cell, reducing tumor growth and/or treating and preventing cancer. Methods for screening PACE4 inhibitors and cell proliferation inhibitors are further provided.
摘要翻译：本文公开了PACE4抑制剂，包含PACE4抑制剂的组合物及其用于降低PACE4活性，降低细胞增殖，降低肿瘤生长，减少转移形成，预防和/或治疗癌症的用途。还提供降低PACE4活性，减少细胞增殖，降低肿瘤生长和/或治疗和预防癌症的方法。还提供了筛选PACE4抑制剂和细胞增殖抑制剂的方法。

3. 外观设计

USD688577S1 Laser tracker 有权
标题翻译：激光跟踪器
公开(公告)号：USD688577S1
公开(公告)日：2013-08-27
申请号：US29413811
申请日：2012-02-21
申请人： Kenneth Steffey , Jeremy Markee Garey , Jonathan Robert Day , Ian C. McDermott , Ian Vance White , Joseph W. Jackson, Jr. , Matthew Joseph Messinger
设计人： Kenneth Steffey , Jeremy Markee Garey , Jonathan Robert Day , Ian C. McDermott , Ian Vance White , Joseph W. Jackson, Jr. , Matthew Joseph Messinger

4. 发明申请

US20110102174A1 APPARATUS AND METHOD FOR REMOTELY MONITORING AND COMMUNICATING WITH A USER 审中-公开
标题翻译：用户远程监控和通信的设备和方法
公开(公告)号：US20110102174A1
公开(公告)日：2011-05-05
申请号：US12880950
申请日：2010-09-13
申请人： Ronald G. Pace , David Medeiros , Cynthia Fine , Robert Day , Mike Yoshiaki Daikubara
发明人： Ronald G. Pace , David Medeiros , Cynthia Fine , Robert Day , Mike Yoshiaki Daikubara
IPC分类号： G08B1/08
CPC分类号： G08B21/0208
摘要： A baby monitor including a receiver configured to receive a plurality of digital signals, each produced by a separate electrical unit and representing an audible acoustical signal. The baby monitor also including a speaker configured to output the sounds represented by the plurality of digital signals, a microphone configured to detect sound waves generated by a first user, a CODEC configured to convert the sound waves generated by the first user to a digital signal, and a transmitter. The transmitter operable in a first mode, in which the transmitter transmits the digital signal representative of the sound waves generated by the first user to less than all of the electrical units from which it has received digital signals.
摘要翻译：一种婴儿监视器，包括被配置为接收多个数字信号的接收器，每个数字信号由单独的电气单元产生并且表示可听见的声音信号。婴儿监视器还包括被配置为输出由多个数字信号表示的声音的扬声器，被配置为检测由第一用户生成的声波的麦克风，被配置为将由第一用户生成的声波转换为数字信号的CODEC 和发射机。发射机可在第一模式下操作，其中发射机将代表第一用户产生的声波的数字信号发送到小于接收数字信号的所有电单元。

5. 发明申请

US20110064568A1 Fluid Pump 有权
标题翻译：流体泵
公开(公告)号：US20110064568A1
公开(公告)日：2011-03-17
申请号：US12901671
申请日：2010-10-11
申请人： Terence Robert Day
发明人： Terence Robert Day
IPC分类号： F04D29/42
CPC分类号： F04D17/10 , F04D29/2277
摘要： An apparatus for pumping or compressing a fluid, the apparatus comprising: a housing having a front wall, a rear wall and one or more side walls interconnecting the front and rear walls to define a fluid rotation chamber; at least one inlet located substantially centrally in the front wall; an impeller located at least partially within the at least one inlet such that at least a portion of the impeller extends outwardly beyond at least a portion of the front wall; and at least one outlet, wherein rotation of the impeller causes fluid entering the apparatus through the at least one inlet to rotate within the fluid rotation chamber prior to exiting the apparatus through the at least one outlet.
摘要翻译：一种用于泵送或压缩流体的装置，所述装置包括：壳体，其具有前壁，后壁和互连所述前壁和后壁以限定流体旋转室的一个或多个侧壁; 至少一个入口大致位于前壁的中心; 叶轮，其至少部分地位于所述至少一个入口内，使得所述叶轮的至少一部分向外延伸超过所述前壁的至少一部分; 以及至少一个出口，其中叶轮的旋转导致通过所述至少一个入口进入设备的流体，以在离开设备通过至少一个出口之前在流体旋转室内旋转。

6. 发明申请

US20100007167A1 VEHICLE SEAT 有权
标题翻译：车辆座椅
公开(公告)号：US20100007167A1
公开(公告)日：2010-01-14
申请号：US12439347
申请日：2007-09-05
申请人： Makoto Ito , Yoshihiro Ooishi , Tomohiro Muramatsu , Osamu Fujimoto , Robert Day
发明人： Makoto Ito , Yoshihiro Ooishi , Tomohiro Muramatsu , Osamu Fujimoto , Robert Day
IPC分类号： B60N2/30 , B60N2/02 , B60N2/22
CPC分类号： B60N2/22 , B60N2/3011 , B60N2/3065 , B60N2/3075 , B60N2/309 , B60N2/856
摘要： A vehicle seat is taught that preferably include a seat cushion (10), a seat back (20) rotatably connected to the seat cushion via a reclining mechanism (30), front (40) and rear (46) legs removably connecting the seat cushion to a vehicle floor (66), a retracting link (50), an operating member capable of removing the front and rear legs from the floor, and a coupling link (54). The seat back can be rotated forwardly by unlocking the reclining mechanism, so as to be superimposed on the seat cushion. When the front and rear legs are removed from the floor, the seat can be moved from a use condition to a retracted condition depending on the motion of the retracting link. When the seat is moved from the use condition to the retracted condition, the coupling link rotates the front leg based on a displacement of the retracting link, thereby unlocking the reclining mechanism
摘要翻译：教导车辆座椅，其优选地包括座垫（10），座椅靠背（20），其经由倾斜机构（30）可旋转地连接到座垫，前部（40）和后部（46）腿部可移除地连接座垫到车辆地板（66），收回连杆（50），能够从地板上移除前腿和后腿的操作构件以及联接杆（54）。座椅靠背可以通过解锁倾斜机构向前旋转，以便重叠在座垫上。当前腿和后腿从地板上取下时，座椅可以根据收回链节的运动从使用状态移动到缩回状态。当座椅从使用状态移动到缩回状态时，联接连杆基于回缩连杆的位移使前腿旋转，由此解锁倾斜机构

7. 发明申请

US20080291593A1 Device protection using temperature compensation 有权
标题翻译：器件保护采用温度补偿
公开(公告)号：US20080291593A1
公开(公告)日：2008-11-27
申请号：US12154328
申请日：2008-05-22
申请人： Timothy Robert Day , Daniel Patrick Roth
发明人： Timothy Robert Day , Daniel Patrick Roth
IPC分类号： H02H3/00 , H02H7/00
CPC分类号： H02H7/06 , H02H3/40
摘要： Device protection using temperature compensation. A logic module associated with groups of capacitors adjusts complex impedance planes associated with the capacitor groups to account for ambient temperature variations. In particular, the logic module is configured to adjust a center of a circle of each complex impedance plane based on an average impedance. The average impedance for a selected capacitor group includes impedance measurements for groups other than the selected group, to prevent capacitor failures in that group from skewing the average. The logic module can adjust the circle center in response to changes in average impedance over periods of time. For example, the logic module can filter measured differences in average impedance using a low pass filter, to distinguish slow impedance changes caused by temperature variations and rapid impedance changes caused by capacitor failures. The logic module can adjust the circle center in accordance with the filtered difference value.
摘要翻译：器件保护采用温度补偿。与电容器组相关联的逻辑模块调整与电容器组相关联的复阻抗平面以考虑环境温度变化。特别地，逻辑模块被配置为基于平均阻抗来调整每个复阻抗平面的圆的中心。所选电容器组的平均阻抗包括除了所选组之外的组的阻抗测量，以防止该组中的电容器故障偏移平均值。逻辑模块可以响应于一段时间内平均阻抗的变化来调整圆心。例如，逻辑模块可以使用低通滤波器来滤除平均阻抗的测量差异，以区分由温度变化引起的慢阻抗变化和由电容器故障引起的快速阻抗变化。逻辑模块可以根据滤波后的差值调整圆心。

8. 发明申请

US20070072660A1 Conveyor feeder house chain slat 有权
标题翻译：输送机房子链条板条
公开(公告)号：US20070072660A1
公开(公告)日：2007-03-29
申请号：US11350146
申请日：2006-02-08
申请人： Robert Day , Ryan Mackin , Mark Payne
发明人： Robert Day , Ryan Mackin , Mark Payne
IPC分类号： A01D17/02
CPC分类号： A01D61/04 , B65G19/10 , B65G19/22
摘要： A new and improved conveyor feeder house chain slat having a unique shape and structure that provides sufficient structural rigidity to improve crop throughput while reducing clogging of crop material. The unique slat also provides additional support to the chain. Because the chain rides on the rear of the elongated section of the slat, the slat contacts the feed house, rather than the chain, reducing chain wear, overheating and lubricant evacuation. Because of the new slat configuration, the slats can be secured to the chain with removable securing means, enabling easier replacement of an individual slat if necessary.
摘要翻译：一种新的和改进的输送机喂料室链条板条，其具有独特的形状和结构，其提供足够的结构刚度以改善作物产量，同时减少作物材料的堵塞。独特的条纹还为链条提供了额外的支持。因为链条沿着板条的细长部分的后部，板条接触进料室，而不是链条，减少链条磨损，过热和润滑剂排出。由于新的板条配置，板条可以用可拆卸的固定装置固定到链条上，如果需要，可以更容易地更换单个板条。

9. 发明申请

US20060020899A1 Scaling icons for representing files 有权
标题翻译：缩放用于表示文件的图标
公开(公告)号：US20060020899A1
公开(公告)日：2006-01-26
申请号：US11186827
申请日：2005-07-22
申请人： Paul Gusmorino , Tyler Beam , Raymond Chen , Charles Cummins , Robert Day , Colin Anthony , Jenny Lam , Isaac Sheldon , David De Vorchik
发明人： Paul Gusmorino , Tyler Beam , Raymond Chen , Charles Cummins , Robert Day , Colin Anthony , Jenny Lam , Isaac Sheldon , David De Vorchik
IPC分类号： G06F3/00
CPC分类号： G06F3/04817
摘要： A method and system are provided for displaying icons in accordance with user preferences. The method includes providing a user with a size selection mechanism for selecting an icon size from a range of sizes. The method additionally includes searching a set of stored resources related to the underlying file and generating the icon in the selected size based upon the stored resources. The method may additionally include selecting an icon type including one of an image icon, a detail icon and a generic icon based on at least one of the user's size selection and the represented file. Furthermore, the icon display system of the invention positions labels and overlays in the vicinity of the icon based upon the selected size of the icon.
摘要翻译：提供了一种根据用户偏好来显示图标的方法和系统。该方法包括向用户提供用于从尺寸范围中选择图标尺寸的尺寸选择机构。该方法还包括搜索与底层文件相关的一组存储的资源，并且基于所存储的资源生成所选大小的图标。该方法可以另外包括基于用户的大小选择和所表示的文件中的至少一个来选择包括图像图标，细节图标和通用图标之一的图标类型。此外，本发明的图标显示系统基于所选择的图标的尺寸，在图标附近定位标签和叠加。

10. 发明申请

US20050240878A1 System and method for scaling icons 审中-公开
标题翻译：用于缩放图标的系统和方法
公开(公告)号：US20050240878A1
公开(公告)日：2005-10-27
申请号：US10831145
申请日：2004-04-26
申请人： Colin Anthony , Tyler Beam , Raymond Chen , Charles Cummins , Robert Day , Paul Gusmorino , Jenny Lam , Isaac Sheldon , David De Vorchik
发明人： Colin Anthony , Tyler Beam , Raymond Chen , Charles Cummins , Robert Day , Paul Gusmorino , Jenny Lam , Isaac Sheldon , David De Vorchik
IPC分类号： G06F3/00 , G06F3/048 , G06F9/00 , G06F17/00
CPC分类号： G06F3/04817
摘要： A method and system are provided for displaying icons in accordance with user preferences. The method includes providing a user with a size selection mechanism for selecting an icon size from a range of sizes. The method additionally includes searching a set of stored resources related to the underlying file and generating the icon in the selected size based upon the stored resources. The method may additionally include selecting an icon type including one of a traditional icon and thumbnail icon based on at least one of the user's size selection and the represented file. Furthermore, the icon display system of the invention positions labels and overlays in the vicinity of the icon based upon the selected size of the icon.
摘要翻译：提供了一种根据用户偏好来显示图标的方法和系统。该方法包括向用户提供用于从尺寸范围中选择图标尺寸的尺寸选择机构。该方法还包括搜索与底层文件相关的一组存储的资源，并且基于所存储的资源生成所选大小的图标。该方法可以另外包括基于用户的大小选择和所表示的文件中的至少一个来选择包括传统图标和缩略图图标之一的图标类型。此外，本发明的图标显示系统基于所选择的图标的尺寸，在图标附近定位标签和叠加。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式