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1. 发明授权

US10568655B2 Atherectomy catheters devices having multi-channel bushings 有权
公开(公告)号：US10568655B2
公开(公告)日：2020-02-25
申请号：US15457960
申请日：2017-03-13
申请人： John B. Simpson , Himanshu N. Patel , Anthony J. Fernandez , Richard R. Newhauser
发明人： John B. Simpson , Himanshu N. Patel , Anthony J. Fernandez , Richard R. Newhauser
IPC分类号： A61B17/3207 , A61B5/00 , A61M25/00 , A61B90/00
摘要： Atherectomy catheters and methods of using them are described herein. In particular, described herein are optical coherence tomography (OCT) catheters that may include a distal tip that can be deflected away from the long axis of the device using a multi-channel bushing. The bushing may include at a hinge point that is offset (e.g., located on a side of the elongate body near the distal end of the elongate body) and a rotatable cutter near an imaging assembly that can be driven against the wall with a high mechanical advantage.

2. 发明授权

US09060892B2 Stent with independent stent rings and transitional attachments 有权
标题翻译：支架具有独立的支架环和过渡附件
公开(公告)号：US09060892B2
公开(公告)日：2015-06-23
申请号：US13063911
申请日：2009-09-11
申请人： Randolf Von Oepen , Lorcan James Coffey , Richard R. Newhauser , Thomas Rieth , Travis R. Yribarren
发明人： Randolf Von Oepen , Lorcan James Coffey , Richard R. Newhauser , Thomas Rieth , Travis R. Yribarren
IPC分类号： A61F2/06 , A61F2/915 , A61F2/91 , A61F2/89 , A61F2/95 , A61F2/958 , A61F2/82
CPC分类号： A61F2/915 , A61F2/89 , A61F2/91 , A61F2/95 , A61F2/958 , A61F2002/30019 , A61F2002/30484 , A61F2002/826 , A61F2002/828 , A61F2002/91583 , A61F2002/91591 , A61F2210/0004 , A61F2210/0014 , A61F2210/0076 , A61F2250/0071
摘要： A vascular endoprosthesis (100, 200, 300, 400, 500, 600) includes a radially-expandable first segment and a radially expandable second segment. The vascular endoprosthesis further includes first and second coupling elements. The first coupling element extends from the proximal end of the first segment toward the distal end of the second segment, and the second coupling element extends from the distal end of the second segment toward the proximal end of the first segment. The first and second coupling elements cooperate one with another to couple the first and second segments together when the vascular endoprosthesis is in a delivery configuration and to decouple the first and second segments when the vascular endoprosthesis is in a deployed configuration.
摘要翻译：血管内假体（100,200,300,400,500,600）包括径向可扩张的第一段和可径向扩张的第二段。血管内假体进一步包括第一和第二联接元件。第一联接元件从第一段的近端延伸到第二段的远端，并且第二联接元件从第二段的远端朝向第一段的近端延伸。当血管内用假体处于输送构型中时，第一和第二联接元件彼此配合以将第一和第二段联接在一起，并且当血管内用假体处于展开构型时将第一和第二段分离。

3. 发明授权

US08452392B2 Systems and methods for anesthetizing ear tissue 有权
标题翻译：用于麻醉耳朵组织的系统和方法
公开(公告)号：US08452392B2
公开(公告)日：2013-05-28
申请号：US12510217
申请日：2009-07-27
申请人： John H. Morriss , Greg Liu , Rohit Girotra , Bernard H. Andreas , Scott J. Baron , Paul G. Hayter , Thomas Jenkins , Richard R. Newhauser, Jr. , Jeffrey A. Walker
发明人： John H. Morriss , Greg Liu , Rohit Girotra , Bernard H. Andreas , Scott J. Baron , Paul G. Hayter , Thomas Jenkins , Richard R. Newhauser, Jr. , Jeffrey A. Walker
IPC分类号： A61N1/30
CPC分类号： A61N1/306 , A61F11/00 , A61M1/0088 , A61M19/00 , A61M2205/3341 , A61M2210/0662 , A61N1/044 , A61N1/303 , A61N1/36021
摘要： A system and method for use in iontophoretic anesthesia of a tympanic membrane are disclosed. The system generally includes an earplug and an electrode device. The earplug includes at least one sealing member for sealing the earplug in an ear canal. The method involves using the system on a human or animal subject.
摘要翻译：公开了一种用于鼓膜离子电渗麻醉的系统和方法。该系统通常包括耳塞和电极装置。耳塞包括用于将耳塞密封在耳道中的至少一个密封构件。该方法涉及将该系统用于人或动物受试者。

4. 发明申请

US20120071856A1 Medical Device and Method for Treatment of a Sinus Opening 有权
标题翻译：治疗窦开口的医疗器械和方法
公开(公告)号：US20120071856A1
公开(公告)日：2012-03-22
申请号：US13222353
申请日：2011-08-31
申请人： Eric A. Goldfarb , Richard R. Newhauser, JR. , Thomas R. Jenkins , John W. White , Mina W.B. Chow , Serena Swei Loh , Mei Y. Pader , Scott O. Chamness , Luke W. Clauson , Matthew B. Newell , Arthur M. Lin
发明人： Eric A. Goldfarb , Richard R. Newhauser, JR. , Thomas R. Jenkins , John W. White , Mina W.B. Chow , Serena Swei Loh , Mei Y. Pader , Scott O. Chamness , Luke W. Clauson , Matthew B. Newell , Arthur M. Lin
IPC分类号： A61M25/10 , A61M1/00
CPC分类号： A61M25/09041 , A61B17/24 , A61B17/3207 , A61B2017/00292 , A61B2017/00331 , A61B2017/00535 , A61B2017/22042 , A61B2017/22069 , A61M3/0295 , A61M25/0113 , A61M29/00 , A61M29/02 , A61M2025/0681 , A61M2025/09125 , A61M2210/0618
摘要： A medical device and method for the treatment of a sinus opening includes a handle, a guide catheter, a guide wire, a balloon catheter, a guide wire movement mechanism and a balloon catheter movement mechanism. The handle has proximal and distal ends and a longitudinal axis along the length of the handle. The guide catheter is attached to the distal end of the handle and has a catheter lumen. The guide wire and balloon catheter are both disposed at least partially in the handle and catheter lumen. The guide wire movement mechanism and the balloon catheter movement mechanism are both operatively disposed on the handle. In addition, the guide wire movement mechanism is configured for advancement and retraction of the guide wire through the handle and catheter lumen by user operation of the guide wire movement mechanism. Moreover, the guide wire movement mechanism includes an integrated guide wire locking and rotation mechanism configured for rotation of the guide wire and for securely locking and unlocking the guide wire to the guide wire movement mechanism. Furthermore, the balloon catheter movement mechanism is configured for advancement and retraction of the balloon catheter through the handle and catheter lumen by user operation of the balloon catheter movement mechanism.
摘要翻译：用于治疗窦口的医疗装置和方法包括手柄，引导导管，导丝，气囊导管，导丝移动机构和气囊导管移动机构。手柄具有近端和远端以及沿手柄长度的纵向轴线。引导导管附接到手柄的远端并具有导管内腔。引导线和气囊导管至少部分地设置在手柄和导管腔中。引导线移动机构和气囊导管移动机构都可操作地设置在手柄上。此外，引导线移动机构构造成用于通过导丝运动机构的用户操作使导丝通过手柄和导管腔进行和缩回。此外，引导线移动机构包括被构造成用于旋转引导线并且用于将引导线牢固地锁定和解锁到引导线移动机构的一体的导丝线锁定和旋转机构。此外，球囊导管移动机构构造成用于通过球囊导管移动机构的用户操作通过手柄和导管腔进行和缩回气囊导管。

5. 发明申请

US20100198135A1 SYSTEMS AND METHODS FOR ANESTHETIZING EAR TISSUE 有权
标题翻译：用于麻醉组织的系统和方法
公开(公告)号：US20100198135A1
公开(公告)日：2010-08-05
申请号：US12650469
申请日：2009-12-30
申请人： John H. Morriss , Greg Liu , Rohit Girotra , Bernard H. Andreas , Scott J. Baron , Paul G. Hayter , Thomas Jenkins , Richard R. Newhauser, JR. , Jeffrey A. Walker
发明人： John H. Morriss , Greg Liu , Rohit Girotra , Bernard H. Andreas , Scott J. Baron , Paul G. Hayter , Thomas Jenkins , Richard R. Newhauser, JR. , Jeffrey A. Walker
IPC分类号： A61N1/30
CPC分类号： A61N1/325 , A61F11/00 , A61K9/0009 , A61K9/0046 , A61M1/0088 , A61M3/0254 , A61M3/0279 , A61M19/00 , A61M31/002 , A61M2202/048 , A61M2205/3341 , A61M2210/0662 , A61M2210/0668 , A61N1/0526 , A61N1/303 , A61N1/36021
摘要： A system and method for use in iontophoretic anesthesia of a tympanic membrane are disclosed. The system generally includes an earplug and an electrode device. The earplug includes at least one sealing member for sealing the earplug in an ear canal. The sealing member includes microholes which vent fluid above a certain pressure threshold. A headset may connect the earplug to a second earplug. The method involves using the system on a human or animal subject.
摘要翻译：公开了一种用于鼓膜离子电渗麻醉的系统和方法。该系统通常包括耳塞和电极装置。耳塞包括用于将耳塞密封在耳道中的至少一个密封构件。密封构件包括将流体排出高于特定压力阈值的微孔。耳机可以将耳塞连接到第二个耳塞。该方法涉及将该系统用于人或动物受试者。

6. 发明申请

US20100076377A1 Expandable Member Formed Of A Fibrous Matrix Having Hydrogel Polymer For Intraluminal Drug Delivery 有权
标题翻译：具有用于腔内药物递送的水凝胶聚合物的纤维基质的可膨胀构件
公开(公告)号：US20100076377A1
公开(公告)日：2010-03-25
申请号：US12238026
申请日：2008-09-25
申请人： Kevin J. Ehrenreich , Richard R. Newhauser , Randolf von Oepen , John Stankus
发明人： Kevin J. Ehrenreich , Richard R. Newhauser , Randolf von Oepen , John Stankus
IPC分类号： A61M29/00 , A61M31/00
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/606 , A61M25/104 , A61M2025/1031 , A61M2025/105 , A61M2025/1075 , A61M2025/1088
摘要： An intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent incorporated therein. The hydrogel polymer can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a second coating including a protective substance surrounding the hydrogel polymer having a therapeutic agent therein. The matrix of fiber elements can be formed by electrospinning. A process of delivering a therapeutic agent to a target site includes providing an intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent dispersed therein, and advancing the catheter device at a desired treatment site. Once at the desired treatment site, fluid is introduced into the inflation lumen to expand the expandable member from a first profile to a second profile, and the therapeutic agent is released from the hydrogel polymer and delivered to the desired treatment site.
摘要翻译：一种管腔内导管装置，其具有由纤维元件基质形成的可膨胀构件，所述可扩张构件包括其中结合有治疗剂的水凝胶聚合物。水凝胶聚合物可以以同轴构型涂覆在纤维元件上。纤维元件还可以具有包含围绕水凝胶聚合物的保护性物质的第二涂层，其中具有治疗剂。纤维元素的基质可以通过静电纺丝形成。将治疗剂递送到靶位置的过程包括提供具有由纤维元件基质形成的可扩张构件的管腔内导管装置，所述可扩张构件包括其中分散有治疗剂的水凝胶聚合物，并将导管装置推进到所需治疗部位。一旦在期望的治疗部位，将流体引入充气腔，以将可膨胀构件从第一轮廓扩张到第二轮廓，并且将治疗剂从水凝胶聚合物释放并递送到所需的治疗部位。

7. 发明申请

US20100010622A1 HYBRID SEGMENTED ENDOPROSTHESIS 审中-公开
标题翻译：混合内分泌肿瘤
公开(公告)号：US20100010622A1
公开(公告)日：2010-01-14
申请号：US12548268
申请日：2009-08-26
申请人： David Lowe , Rainer Bregulla , Richard R. Newhauser , Travis R. Yribarren
发明人： David Lowe , Rainer Bregulla , Richard R. Newhauser , Travis R. Yribarren
IPC分类号： A61F2/06 , B23P11/00 , B21D39/00
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/3008 , A61F2002/30329 , A61F2002/826 , A61F2002/828 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2220/0025 , A61F2220/005 , A61F2220/0058 , A61F2230/0054 , A61F2240/001 , A61F2250/0014 , A61F2250/0018 , A61F2250/0036 , A61F2250/0039 , A61F2250/0042 , A61F2250/0067 , A61F2250/0098 , Y10T29/49826 , Y10T29/49888 , Y10T29/49906
摘要： Generally, the present disclosure includes a hybrid segmented endoprosthesis for delivery into a lumen of a body. The hybrid segmented endoprosthesis has different types of segments that are joined together. The segments are typically distinct and distinguishable from each other by each segment having a unique configuration different from at least one other segment. Additionally, the segments can be coupled together by various processes well known for interconnecting the materials of endoprostheses. The segmented endoprosthesis can provide improved deliverability, strength, flexibility, and/or functionality during and after deployment. The use of a segmented endoprosthesis can combine the configurations of multiple small endoprostheses into a standard- or regular-sized endoprosthesis.
摘要翻译：通常，本公开包括用于输送到身体的内腔中的混合分段内用假体。混合分段内假体具有连接在一起的不同类型的段。通过每个段具有不同于至少一个其它段的独特构造，段通常是不同的和可区分的。另外，通过众所周知的用于互连内裤的材料的各种方法，片段可以联结在一起。分段内假体可以在部署期间和之后提供改进的可交付性，强度，灵活性和/或功能。使用分段内假体可以将多个小型内假体的构型组合成标准尺寸或正常大小的内置假体。

8. 发明申请

US20170273711A1 ATHERECTOMY CATHETERS DEVICES HAVING MULTI-CHANNEL BUSHINGS 审中-公开
公开(公告)号：US20170273711A1
公开(公告)日：2017-09-28
申请号：US15457960
申请日：2017-03-13
申请人： John B. SIMPSON , Himanshu N. PATEL , Anthony J. FERNANDEZ , Richard R. NEWHAUSER
发明人： John B. SIMPSON , Himanshu N. PATEL , Anthony J. FERNANDEZ , Richard R. NEWHAUSER
IPC分类号： A61B17/3207 , A61B5/00 , A61M25/00
摘要： Atherectomy catheters and methods of using them are described herein. In particular, described herein are optical coherence tomography (OCT) catheters that may include a distal tip that can be deflected away from the long axis of the device using a multi-channel bushing. The bushing may include at a hinge point that is offset (e.g., located on a side of the elongate body near the distal end of the elongate body) and a rotatable cutter near an imaging assembly that can be driven against the wall with a high mechanical advantage.

9. 发明申请

US20160192962A1 ATHERECTOMY CATHETERS DEVICES HAVING MULTI-CHANNEL BUSHINGS 有权
标题翻译：具有多通道布线的ATHERECTOMH导管装置
公开(公告)号：US20160192962A1
公开(公告)日：2016-07-07
申请号：US15072272
申请日：2016-03-16
申请人： John B. SIMPSON , Himanshu N. PATEL , Anthony J. FERNANDEZ , Richard R. NEWHAUSER
发明人： John B. SIMPSON , Himanshu N. PATEL , Anthony J. FERNANDEZ , Richard R. NEWHAUSER
IPC分类号： A61B17/3207 , A61B5/00 , A61M25/00
CPC分类号： A61B17/320783 , A61B5/0066 , A61B5/0084 , A61B17/320758 , A61B2017/320791 , A61B2090/3735 , A61M25/0043 , A61M25/0068 , A61M25/0074 , A61M25/0082
摘要： Atherectomy catheters and methods of using them are described herein. In particular, described herein are optical coherence tomography (OCT) catheters that may include a distal tip that can be deflected away from the long axis of the device using a multi-channel bushing. The bushing may include at a hinge point that is offset (e.g., located on a side of the elongate body near the distal end of the elongate body) and a rotatable cutter near an imaging assembly that can be driven against the wall with a high mechanical advantage.
摘要翻译：动脉粥样斑块切除术导管及其使用方法在本文中描述。特别地，这里描述的是光学相干断层摄影（OCT）导管，其可以包括可以使用多通道套管从装置的长轴偏转远端。衬套可以包括在偏移的铰链点处（例如，位于细长体的靠近细长主体的远端的一侧）以及靠近成像组件的可旋转切割器，其可以用高机械优点。

10. 发明授权

US08840602B2 Systems and methods for anesthetizing ear tissue 有权
标题翻译：用于麻醉耳朵组织的系统和方法
公开(公告)号：US08840602B2
公开(公告)日：2014-09-23
申请号：US12650469
申请日：2009-12-30
申请人： John H. Morriss , Greg Liu , Rohit Girotra , Bernard H. Andreas , Scott J. Baron , Paul G. Hayter , Thomas Jenkins , Richard R. Newhauser, Jr. , Jeffrey A. Walker
发明人： John H. Morriss , Greg Liu , Rohit Girotra , Bernard H. Andreas , Scott J. Baron , Paul G. Hayter , Thomas Jenkins , Richard R. Newhauser, Jr. , Jeffrey A. Walker
IPC分类号： A61M31/00 , A61F11/00 , A61K9/00 , A61M3/02 , A61N1/30 , A61M1/00 , A61M19/00 , A61F11/08 , A61N1/36
CPC分类号： A61N1/325 , A61F11/00 , A61K9/0009 , A61K9/0046 , A61M1/0088 , A61M3/0254 , A61M3/0279 , A61M19/00 , A61M31/002 , A61M2202/048 , A61M2205/3341 , A61M2210/0662 , A61M2210/0668 , A61N1/0526 , A61N1/303 , A61N1/36021
摘要： A system and method for use in iontophoretic anesthesia of a tympanic membrane are disclosed. The system generally includes an earplug and an electrode device. The earplug includes at least one sealing member for sealing the earplug in an ear canal. The sealing member includes microholes which vent fluid above a certain pressure threshold. A headset may connect the earplug to a second earplug. The method involves using the system on a human or animal subject.
摘要翻译：公开了一种用于鼓膜离子电渗麻醉的系统和方法。该系统通常包括耳塞和电极装置。耳塞包括用于将耳塞密封在耳道中的至少一个密封构件。密封构件包括将流体排出高于特定压力阈值的微孔。耳机可以将耳塞连接到第二个耳塞。该方法涉及将该系统用于人或动物受试者。

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