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1. 发明申请

US20130062893A1 PRESSURE VESSEL SAFETY LOCK APPARATUS 有权
公开(公告)号：US20130062893A1
公开(公告)日：2013-03-14
申请号：US13598873
申请日：2012-08-30
申请人： Richard McLaughlin , Cliff LaFrenz , Chris Gramling
发明人： Richard McLaughlin , Cliff LaFrenz , Chris Gramling
IPC分类号： B65D45/34 , E05B65/00
CPC分类号： E05B65/001 , E05B51/02 , E05C19/18 , F16J13/24 , Y10T292/20 , Y10T292/205 , Y10T292/212 , Y10T292/228
摘要： The present disclosure provides a locking device for restricting access to a hatch of a pressure vessel, and, more specifically, a locking device that is responsive to the internal pressure in the pressure vessel so as to minimize the ability of one to open the hatch while the vessel is still pressurized. In some embodiments, the locking device comprises first and second portions of the locking device configurable between an open and a closed configuration and a pressure-responsive locking member in fluid communication with an outlet port of the pressure vessel and arranged to automatically retain the first and second portions in the closed configuration when the pressure inside of the pressure vessel is above a predetermined threshold, wherein in the closed configuration the first and second portions restrict manipulation of the hatch and/or a locking mechanism of the hatch.

2. 外观设计

USD829448S1 Patches for motorcycle jackets 有权
公开(公告)号：USD829448S1
公开(公告)日：2018-10-02
申请号：US35001047
申请日：2015-07-09
申请人： Richard McLaughlin
设计人： Richard McLaughlin

3. 发明申请

US20070259300A1 ORTHODONTIC BRACE WITH COORDINATED BRACKET PROFILES 审中-公开
标题翻译：具有协调支架轮廓的正齿面
公开(公告)号：US20070259300A1
公开(公告)日：2007-11-08
申请号：US11381565
申请日：2006-05-04
申请人： Richard McLaughlin , Ming-Lai Lai
发明人： Richard McLaughlin , Ming-Lai Lai
IPC分类号： A61C3/00
CPC分类号： A61C7/12 , A61C7/14
摘要： A set of orthodontic brackets is constructed according to preferred parameters of a Deviation Index in order to provide an orthodontic brace that facilitates movement of teeth to ideal positions. The brace also helps eliminate the need to manually bend the archwire during the final stages of treatment such that chair time is reduced.
摘要翻译：根据偏差指数的优选参数构建一组正畸托架，以提供便于牙齿移动到理想位置的正畸支架。支架还有助于消除在治疗的最后阶段期间手动弯曲弓丝的需要，从而减少椅子时间。

4. 发明申请

US20050215562A1 Methods for treating protein aggregation disorders 审中-公开
标题翻译：治疗蛋白质聚集障碍的方法
公开(公告)号：US20050215562A1
公开(公告)日：2005-09-29
申请号：US10874805
申请日：2004-06-22
申请人： Patrick Tremblay , Richard McLaughlin
发明人： Patrick Tremblay , Richard McLaughlin
IPC分类号： A61K31/205 , A61K31/445 , A61K31/495
CPC分类号： A61K31/205 , A61K31/445 , A61K31/495
摘要： The present invention is based, at least in part on the discovery of therapeutic agents capable of preventing, inhibiting or modulating abnormal processing, misfolding or aggregation of protein. The therapeutic agents of the invention may prevent, inhibit or modulate the formation of inclusions. The therapeutic agents of the invention may also be capable of facilitating clearance and/or blocking the cellular toxicity of inclusions to treat or ameliorate disorders characterized by protein aggregation. Compounds which bind to structural motifs commonly found in protein aggregates, such as β-sheets, would represent strong candidates for such compounds and are therefore desirable.
摘要翻译：本发明至少部分地基于能够预防，抑制或调节异常加工，蛋白质错误折叠或聚集的治疗剂的发现。本发明的治疗剂可以预防，抑制或调节夹杂物的形成。本发明的治疗剂还可以有助于清除和/或阻断夹杂物的细胞毒性，以治疗或改善以蛋白质聚集为特征的病症。通常在蛋白质聚集体中发现的结构基序结合的化合物，例如β-折叠片，将代表这些化合物的强候选物，因此是理想的。

5. 发明授权

US08985646B2 Pressure vessel safety lock apparatus 有权
标题翻译：压力容器安全锁装置
公开(公告)号：US08985646B2
公开(公告)日：2015-03-24
申请号：US13598873
申请日：2012-08-30
申请人： Richard McLaughlin , Cliff LaFrenz , Chris Gramling
发明人： Richard McLaughlin , Cliff LaFrenz , Chris Gramling
IPC分类号： B65D45/30 , F16J13/24 , E05B51/02 , E05B65/00 , E05C19/18
CPC分类号： E05B65/001 , E05B51/02 , E05C19/18 , F16J13/24 , Y10T292/20 , Y10T292/205 , Y10T292/212 , Y10T292/228
摘要： The present disclosure provides a locking device for restricting access to a hatch of a pressure vessel, and, more specifically, a locking device that is responsive to the internal pressure in the pressure vessel so as to minimize the ability of one to open the hatch while the vessel is still pressurized. In some embodiments, the locking device comprises first and second portions of the locking device configurable between an open and a closed configuration and a pressure-responsive locking member in fluid communication with an outlet port of the pressure vessel and arranged to automatically retain the first and second portions in the closed configuration when the pressure inside of the pressure vessel is above a predetermined threshold, wherein in the closed configuration the first and second portions restrict manipulation of the hatch and/or a locking mechanism of the hatch.
摘要翻译：本公开提供了一种用于限制进入压力容器的舱口的锁定装置，更具体地说，是一种响应压力容器内部压力的锁定装置，以便最小化打开舱口的能力，船只仍然受压。在一些实施例中，锁定装置包括锁定装置的第一和第二部分，其可配置在打开和闭合构型之间，以及压力响应锁定构件，其与压力容器的出口流体连通并被布置成自动保持第一和当所述压力容器内部的压力高于预定阈值时，所述第二部分处于所述封闭构造，其中在所述关闭构造中，所述第一和第二部分限制所述舱口盖和/或所述舱口的锁定机构的操纵。

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